LOCUS       NM_001012464            2056 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus telomeric repeat binding factor 1 (Terf1), mRNA.
ACCESSION   NM_001012464 XM_238387
VERSION     NM_001012464.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2056)
  AUTHORS   Tong AS, Stern JL, Sfeir A, Kartawinata M, de Lange T, Zhu XD and
            Bryan TM.
  TITLE     ATM and ATR Signaling Regulate the Recruitment of Human Telomerase
            to Telomeres
  JOURNAL   Cell Rep 13 (8), 1633-1646 (2015)
   PUBMED   26586433
REFERENCE   2  (bases 1 to 2056)
  AUTHORS   Pandita RK, Chow TT, Udayakumar D, Bain AL, Cubeddu L, Hunt CR, Shi
            W, Horikoshi N, Zhao Y, Wright WE, Khanna KK, Shay JW and Pandita
            TK.
  TITLE     Single-strand DNA-binding protein SSB1 facilitates TERT recruitment
            to telomeres and maintains telomere G-overhangs
  JOURNAL   Cancer Res 75 (5), 858-869 (2015)
   PUBMED   25589350
REFERENCE   3  (bases 1 to 2056)
  AUTHORS   Ishiguro K, Kim J, Shibuya H, Hernandez-Hernandez A, Suzuki A,
            Fukagawa T, Shioi G, Kiyonari H, Li XC, Schimenti J, Hoog C and
            Watanabe Y.
  TITLE     Meiosis-specific cohesin mediates homolog recognition in mouse
            spermatocytes
  JOURNAL   Genes Dev 28 (6), 594-607 (2014)
   PUBMED   24589552
REFERENCE   4  (bases 1 to 2056)
  AUTHORS   Yoo JE, Park YN and Oh BK.
  TITLE     PinX1, a telomere repeat-binding factor 1 (TRF1)-interacting
            protein, maintains telomere integrity by modulating TRF1
            homeostasis, the process in which human telomerase reverse
            Transcriptase (hTERT) plays dual roles
  JOURNAL   J Biol Chem 289 (10), 6886-6898 (2014)
   PUBMED   24415760
REFERENCE   5  (bases 1 to 2056)
  AUTHORS   Grolimund L, Aeby E, Hamelin R, Armand F, Chiappe D, Moniatte M and
            Lingner J.
  TITLE     A quantitative telomeric chromatin isolation protocol identifies
            different telomeric states
  JOURNAL   Nat Commun 4, 2848 (2013)
   PUBMED   24270157
REFERENCE   6  (bases 1 to 2056)
  AUTHORS   Shen M, Haggblom C, Vogt M, Hunter T and Lu KP.
  TITLE     Characterization and cell cycle regulation of the related human
            telomeric proteins Pin2 and TRF1 suggest a role in mitosis
  JOURNAL   Proc Natl Acad Sci U S A 94 (25), 13618-13623 (1997)
   PUBMED   9391075
REFERENCE   7  (bases 1 to 2056)
  AUTHORS   Bianchi A, Smith S, Chong L, Elias P and de Lange T.
  TITLE     TRF1 is a dimer and bends telomeric DNA
  JOURNAL   EMBO J 16 (7), 1785-1794 (1997)
   PUBMED   9130722
REFERENCE   8  (bases 1 to 2056)
  AUTHORS   van Steensel B and de Lange T.
  TITLE     Control of telomere length by the human telomeric protein TRF1
  JOURNAL   Nature 385 (6618), 740-743 (1997)
   PUBMED   9034193
REFERENCE   9  (bases 1 to 2056)
  AUTHORS   Chong L, van Steensel B, Broccoli D, Erdjument-Bromage H, Hanish J,
            Tempst P and de Lange T.
  TITLE     A human telomeric protein
  JOURNAL   Science 270 (5242), 1663-1667 (1995)
   PUBMED   7502076
REFERENCE   10 (bases 1 to 2056)
  AUTHORS   Zhong Z, Shiue L, Kaplan S and de Lange T.
  TITLE     A mammalian factor that binds telomeric TTAGGG repeats in vitro
  JOURNAL   Mol Cell Biol 12 (11), 4834-4843 (1992)
   PUBMED   1406665
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC089888.1.
            
            On Apr 20, 2005 this sequence version replaced XM_238387.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC089888.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2056
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q11"
     gene            1..2056
                     /gene="Terf1"
                     /note="telomeric repeat binding factor 1"
                     /db_xref="GeneID:297758"
                     /db_xref="RGD:1311574"
     CDS             1..1266
                     /gene="Terf1"
                     /note="telomeric repeat binding factor (NIMA-interacting)
                     1"
                     /codon_start=1
                     /product="telomeric repeat-binding factor 1"
                     /protein_id="NP_001012482.1"
                     /db_xref="GeneID:297758"
                     /db_xref="RGD:1311574"
                     /translation="MAGTVTSAAPGARSNAGGTSADSPEKEAARDDAELFDCRVQLGP
                     PREEENAELVAEAEAVAAGWMLDFLCLSLCRAFRDGRCEDFRQTRDSAEAIIHGLPSL
                     TAYQLKTVYICQFLTRVAAGKSLDAQFEVDERITPLESALMIWDSIEKEHDKLHEEIQ
                     NLIKIQAVAVCMEMGSFKEAEEVFERIFGDPEFYTPLERKLLKIISQKDVFHVLFQRF
                     SYNLMMEKIQSYVECVLNEKSSTFLMKAATKVVENEKARTVASEDKAKATNTGTETEV
                     NSNKGESVNGQQSVETESLVDTGSSVRSHKNALSPLKSRRLQPDFNRNEARTGTLQCE
                     IATKRNRRTSGGNRLRISKNQPDTNEKHGRRKKQTWLWEEDRSLKCGVRKYGEGNWAK
                     ILSHYKFNNRTSVMLKDRWRTMRRLRLIS"
     exon            1..280
                     /gene="Terf1"
                     /inference="alignment:Splign:2.1.0"
     exon            281..376
                     /gene="Terf1"
                     /inference="alignment:Splign:2.1.0"
     exon            377..498
                     /gene="Terf1"
                     /inference="alignment:Splign:2.1.0"
     exon            499..585
                     /gene="Terf1"
                     /inference="alignment:Splign:2.1.0"
     exon            586..735
                     /gene="Terf1"
                     /inference="alignment:Splign:2.1.0"
     exon            736..848
                     /gene="Terf1"
                     /inference="alignment:Splign:2.1.0"
     exon            849..908
                     /gene="Terf1"
                     /inference="alignment:Splign:2.1.0"
     exon            909..997
                     /gene="Terf1"
                     /inference="alignment:Splign:2.1.0"
     exon            998..1104
                     /gene="Terf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1105..2022
                     /gene="Terf1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggcgggga ctgtcacctc agcagctccg ggcgcgcgga gcaatgcggg cgggacaagc
       61 gcggattctc cagagaagga ggcggcgaga gacgacgcag agttgttcga ctgccgggtg
      121 cagctggggc ccccgagaga ggaggagaac gcggagcttg tggccgaggc ggaggccgtg
      181 gctgcgggct ggatgctcga cttcctctgc ctgtctctgt gccgagcctt tcgcgacggc
      241 cgctgcgagg actttcgcca gactcgtgac agcgccgagg ctattattca tggactaccc
      301 agtcttacag cttaccagtt gaaaactgta tatatatgtc agtttttgac aagagttgca
      361 gcaggaaagt ctcttgatgc acagtttgaa gttgatgagc ggattacacc cttggaatca
      421 gccctgatga tttgggactc aattgaaaaa gaacatgaca aacttcatga agaaatacag
      481 aatttaatta aaattcaggc tgtagctgtg tgtatggaaa tgggcagctt taaggaagca
      541 gaagaagtgt ttgaaagaat atttggtgac ccagaatttt acacgccttt agaaagaaaa
      601 ttacttaaga taatctctca aaaagacgtc ttccacgtcc tttttcaacg cttcagttat
      661 aacctcatga tggagaaaat tcagagttat gtggagtgtg tgttaaatga gaaatcatca
      721 actttcctaa tgaaggcagc aacaaaagta gtggaaaatg aaaaagcaag gacagtagct
      781 tcggaggata aagcaaaggc caccaacact ggaacagaaa cggaagttaa ctcgaataaa
      841 ggagaaagtg ttaatggcca acagtctgta gaaactgaat ccttggtgga tacaggatcc
      901 tcagtaaggt ctcacaagaa tgccttatct ccgttgaaaa gcagacgtct tcagccagat
      961 ttcaatagga atgaagcaag aacaggaact cttcagtgtg aaatagcaac aaaacgaaac
     1021 agaagaacca gtggagggaa tagattacgt atttcaaaga atcagccgga cactaatgaa
     1081 aaacatgggc gcaggaaaaa acagacatgg ctttgggaag aagacagaag tttgaagtgt
     1141 ggtgtaagga aatatggaga gggaaattgg gctaaaatac tatcccatta taagttcaac
     1201 aaccgaacaa gtgtcatgtt aaaggatcgg tggagaacga tgaggaggct aaggctcatt
     1261 agctgagact ccgaaggctg cctgggttgg tttcagctca ctacaggaca gttaaatact
     1321 ggatcactgt gttgtttaaa acttcttggt cagtaaagat gaagcattat tgtgtgtgtg
     1381 tgtgagagag agagtgtgtg aaagagagag ggaatgtgtg ttttgttaca agagatttgt
     1441 actgtaaaag taaaattata tgttatcatt attttctata agaatcttta ttttcataag
     1501 acatagaacc ctaccaaact caagccccat cccatgttgt gttactacag aagcaagagc
     1561 ctaacaaata aagagtacat gactgtcact gcttgtctag tccatgactg taaactgacc
     1621 ttactgagtg ccacctagag atggaccaag ttggaaaaat ctttcgatgt gagtttgctg
     1681 ctggattaat gactagtgta ccacttacta aagagttact actagagggg tatgcaaaac
     1741 gacccatgag ttctaacaag cctggcttgg cttctcaaag tttcatttaa aggaagttgc
     1801 attttcacta aatatttatt cattgcaata tttagtcaaa gactaataat tagcatttga
     1861 gttttatgtg ccatgcttaa caagtaaaaa caagtctcaa cctattgaaa tattaacagg
     1921 aatattactc agcgttgtgt atttcctgca aagtgtcatc actgctttcc tgttctcttg
     1981 aatttgctgt ctgatatata ttaaacagaa tcattaataa ttaaaaaaaa aaaaaaaaaa
     2041 aaaaaaaaaa aaaaaa
//
