LOCUS       NM_001100729            2801 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus TEPSIN, adaptor related protein complex 4
            accessory protein (Tepsin), mRNA.
ACCESSION   NM_001100729 XM_001074705 XM_001081796 XM_001081797 XM_340946
VERSION     NM_001100729.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2801)
  AUTHORS   Frazier,M.N., Davies,A.K., Voehler,M., Kendall,A.K., Borner,G.H.,
            Chazin,W.J., Robinson,M.S. and Jackson,L.P.
  TITLE     Molecular Basis for the Interaction Between AP4 beta4 and its
            Accessory Protein, Tepsin
  JOURNAL   Traffic 17 (4), 400-415 (2016)
   PUBMED   26756312
REFERENCE   2  (bases 1 to 2801)
  AUTHORS   Mattera,R., Guardia,C.M., Sidhu,S.S. and Bonifacino,J.S.
  TITLE     Bivalent Motif-Ear Interactions Mediate the Association of the
            Accessory Protein Tepsin with the AP-4 Adaptor Complex
  JOURNAL   J Biol Chem 290 (52), 30736-30749 (2015)
   PUBMED   26542808
REFERENCE   3  (bases 1 to 2801)
  AUTHORS   Borner,G.H., Antrobus,R., Hirst,J., Bhumbra,G.S., Kozik,P.,
            Jackson,L.P., Sahlender,D.A. and Robinson,M.S.
  TITLE     Multivariate proteomic profiling identifies novel accessory
            proteins of coated vesicles
  JOURNAL   J Cell Biol 197 (1), 141-160 (2012)
   PUBMED   22472443
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1 and BC089956.1.
            
            On or before Feb 16, 2013 this sequence version replaced
            XM_340946.5, XM_001074705.2, XM_001081796.2, XM_001081797.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360172.272552.1,
                                           SRR26360176.302129.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-116               JAXUCZ010000010.1  105879591-105879706 c
            117-189             JAXUCZ010000010.1  105878809-105878881 c
            190-281             JAXUCZ010000010.1  105878344-105878435 c
            282-375             JAXUCZ010000010.1  105878165-105878258 c
            376-443             JAXUCZ010000010.1  105877386-105877453 c
            444-519             JAXUCZ010000010.1  105877099-105877174 c
            520-591             JAXUCZ010000010.1  105876909-105876980 c
            592-795             JAXUCZ010000010.1  105875853-105876056 c
            796-970             JAXUCZ010000010.1  105875447-105875621 c
            971-1061            JAXUCZ010000010.1  105875236-105875326 c
            1062-2801           BC089956.1         1-1740
FEATURES             Location/Qualifiers
     source          1..2801
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q32.3"
     gene            1..2801
                     /gene="Tepsin"
                     /gene_synonym="Enthd2; RGD1307410"
                     /note="TEPSIN, adaptor related protein complex 4 accessory
                     protein"
                     /db_xref="GeneID:360673"
                     /db_xref="RGD:1307410"
     exon            1..116
                     /gene="Tepsin"
                     /gene_synonym="Enthd2; RGD1307410"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..1778
                     /gene="Tepsin"
                     /gene_synonym="Enthd2; RGD1307410"
                     /note="tetra-epsin; ENTH domain-containing protein 2; ENTH
                     domain containing 2"
                     /codon_start=1
                     /product="AP-4 complex accessory subunit tepsin"
                     /protein_id="NP_001094199.1"
                     /db_xref="GeneID:360673"
                     /db_xref="RGD:1307410"
                     /translation="MAAVPPLRDRLSFLHRLPILLKGTSDDDIPCPGYLFEEIAKISH
                     ESLGSSQCLLEYLLNRLDSSSGHVKLKVLKILLYLCSHGSSSFMLILRRNSALIQEAT
                     AFAGPPDPLHGNSLYQKVRAAAQDLGSTLFSDALPQPPSQPPQILPPAGMGAQARPHS
                     ALQGFGYTKESSRTGSAGETFLSTIQRAAEVVVNAVRPGPDNPCTKGPLPHGDAYQPA
                     VTPSASHTHPNPGNLLPAAIQGTRAVKHQPGQAGGGWDEMDSSPSSQNSSCTSNLSRA
                     SDSVSRSGSDSHSGASREPGDLAERAEGMAPNDCQQELNLVRTVTQGPRVFLSREETQ
                     HFIKECGLLNCEAVLELLLQQLVGTSECEQMRALCAIASFGSADLLPQEHILLLCRQQ
                     LQELGAGSPGPVTNKATKILRHLEASCGQQFPTLRPCAQPNSAAAVVGPADLLTSPVP
                     PPGSQVFLQPLSSTAVVPRSPVPTPSPDTLPPALQDPGELRTQLVCSSEPGTGSEQRL
                     ENTDTPKDSSSPCPWSPNSLFAGMELVACTRLPCPSFQADLQKVTTEPPVSEPSAFAF
                     LNM"
     exon            117..189
                     /gene="Tepsin"
                     /gene_synonym="Enthd2; RGD1307410"
                     /inference="alignment:Splign:2.1.0"
     exon            190..281
                     /gene="Tepsin"
                     /gene_synonym="Enthd2; RGD1307410"
                     /inference="alignment:Splign:2.1.0"
     exon            282..375
                     /gene="Tepsin"
                     /gene_synonym="Enthd2; RGD1307410"
                     /inference="alignment:Splign:2.1.0"
     exon            376..443
                     /gene="Tepsin"
                     /gene_synonym="Enthd2; RGD1307410"
                     /inference="alignment:Splign:2.1.0"
     exon            444..519
                     /gene="Tepsin"
                     /gene_synonym="Enthd2; RGD1307410"
                     /inference="alignment:Splign:2.1.0"
     exon            520..591
                     /gene="Tepsin"
                     /gene_synonym="Enthd2; RGD1307410"
                     /inference="alignment:Splign:2.1.0"
     exon            592..795
                     /gene="Tepsin"
                     /gene_synonym="Enthd2; RGD1307410"
                     /inference="alignment:Splign:2.1.0"
     exon            796..970
                     /gene="Tepsin"
                     /gene_synonym="Enthd2; RGD1307410"
                     /inference="alignment:Splign:2.1.0"
     exon            971..1084
                     /gene="Tepsin"
                     /gene_synonym="Enthd2; RGD1307410"
                     /inference="alignment:Splign:2.1.0"
     exon            1085..1163
                     /gene="Tepsin"
                     /gene_synonym="Enthd2; RGD1307410"
                     /inference="alignment:Splign:2.1.0"
     exon            1164..1298
                     /gene="Tepsin"
                     /gene_synonym="Enthd2; RGD1307410"
                     /inference="alignment:Splign:2.1.0"
     exon            1299..2776
                     /gene="Tepsin"
                     /gene_synonym="Enthd2; RGD1307410"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agagaaacgc gacgattgga ggatcgaaac ctggcggaag cgtggcagac tgggaggtta
       61 cctggaccat ggcagccgtt ccgccgctgc gagaccgctt gagctttcta cataggctcc
      121 ccattctgtt gaaggggacc tcagatgatg acatcccatg cccaggctac ctgtttgaag
      181 agattgccaa gatttcccac gagtcactgg gcagcagcca gtgcctgctg gagtacctcc
      241 tgaaccgcct ggacagtagc tctggccacg tgaagctcaa ggtgctgaag atcttgcttt
      301 acctgtgcag tcacggctct tcctccttca tgctcatcct taggagaaac tctgctctca
      361 tccaagaagc cacagctttc gcggggcctc cggatcctct tcatggaaat agcttgtacc
      421 agaaagtgcg ggcggctgcc caggacctgg gtagcaccct cttctcagac gcactgccac
      481 agcctccctc ccagccgccc cagatcctgc ctcctgcagg catgggcgcc caggccaggc
      541 ctcatagtgc tctacaaggc ttcggttata ctaaggagag cagccggaca ggctctgcag
      601 gtgaaacctt cctctccacc atccagaggg ccgcagaggt agtggtgaat gctgtgcgtc
      661 ctgggcctga taatccttgt accaagggac ccctgccaca cggtgatgcc taccagcctg
      721 cagtgacacc ttcagctagc cacacacatc ccaaccccgg gaatctcctc cctgcggcta
      781 tccaggggac cagagctgtg aaacaccagc ccgggcaggc tggaggaggc tgggatgaga
      841 tggacagcag tcctagttcc cagaattcct cctgtaccag caacctgagc agggcctcag
      901 actcagtcag tcggtctggc agtgatagcc actctggtgc cagccgggag ccaggcgacc
      961 tggcagagag ggctgagggc atggccccaa atgactgcca gcaagaactg aatctagtga
     1021 ggactgtgac acaggggcca cgtgtcttcc tgagccgtga ggagacgcag cacttcatca
     1081 aagagtgcgg cctgctcaac tgtgaggctg tgctggagct gctcctccag cagctggtcg
     1141 ggaccagtga gtgtgagcag atgagggcac tgtgtgccat agcgtccttt ggaagtgctg
     1201 acctccttcc tcaggagcac attctcctcc tgtgccgaca gcagctgcag gaacttggtg
     1261 caggcagccc tgggcctgtg accaacaaag ccaccaagat cctgagacac ttggaagcct
     1321 cctgtggaca acagttccct accctaaggc cctgtgccca gcccaactct gcagctgctg
     1381 ttgtgggccc agctgatctg ctgaccagcc ctgtgcctcc ccctgggagc caagtcttcc
     1441 tccagcctct tagttccacc gcagttgtgc ccaggagtcc tgtgcccact ccatctccag
     1501 ataccttacc tcctgctctg caggatcccg gtgagctcag aacccaattg gtatgttcta
     1561 gtgaaccagg gacaggatct gaacagaggc tggagaacac agacacccca aaggatagct
     1621 ccagtccgtg tccgtggagc cccaactctc tgtttgctgg catggagctg gtagcttgca
     1681 cccgcctgcc ctgccccagc ttccaggcag atttgcagaa ggtgaccaca gagcctccag
     1741 tttcagagcc atccgctttt gcatttttaa acatgtgact ttctgggccc cgctgtacag
     1801 agtcccccct ggccctcata tggagttcac catggagtgt tccgtgggtg tcttctggct
     1861 gttcttttgc ccctctggcc ccttcctttc acctaggaaa ctggtacagc ggtctttgag
     1921 ccaggtgatc cctggatgga cctcccagtg ctcagaacag tcactgaaga agacatatgg
     1981 gccctgagtg ctaaccagcc aacctggaag tgtgaaaaat atggtcaact agtgcctcag
     2041 aagatgtctg cacatccact gcttcttggg aagtgactct ggccatgccc ctgagattga
     2101 cttctctcct cctggcaaga cccacacaga ccttcttagc agtctgtcca tagctgaaga
     2161 ccgcctcaga ggtttcccgc tttgtgcagt acatctgcag ggcagtactt ccccagggct
     2221 gctgaccaca gtccctctgc cccatgctgc tctgtctcta ggaggctgaa cactgaggcc
     2281 aactcccagg ctacctcagt cccaggcggg cctgtcccat tgctaggagc tggcaacgat
     2341 cgtatggact tgaactccta tggtgacaga tggcaggtag caaggctgca gctgggtacc
     2401 ctgggcaagc cttgttgggc tgaccctcag aaatgagcac ttgataaggg ttagaaacac
     2461 tgacttggtt cacagttatg ttctgatctc ctttccttcc ttatggaggt caaattagct
     2521 gggagcgaca gccttgagga cagggtgctg gaaaggtgcc tgtggcccag aaggcctcgt
     2581 tctcagcttc ctcagccaag tgccctgtgg ccattgccag tgtcagcccc tgtggggccc
     2641 aactctggat gcacaacttg ccacagtttt ctccagcaca cgggagagtc tcgtctagat
     2701 gaaccttcct gtccatctca gaagagcctg tgaagctgcg ccatgcactt tctcaataaa
     2761 tgcagatgtt tacacaaaaa aaaaaaaaaa aaaaaaaaaa a
//
