LOCUS       NM_019194               4165 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus TEF transcription factor, PAR bZIP family member
            (Tef), mRNA.
ACCESSION   NM_019194
VERSION     NM_019194.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4165)
  AUTHORS   Poon,K., Mandava,S., Chen,K., Barson,J.R., Buschlen,S. and
            Leibowitz,S.F.
  TITLE     Prenatal exposure to dietary fat induces changes in the
            transcriptional factors, TEF and YAP, which may stimulate
            differentiation of peptide neurons in rat hypothalamus
  JOURNAL   PLoS One 8 (10), e77668 (2013)
   PUBMED   24147051
  REMARK    GeneRIF: findings suggest that prenatal HFD exposure inactivates
            both hypothalamic TEF and YAP, by either decreasing their levels or
            increasing their inactive form, and that this contributes to the
            stimulatory effect of HFD on ENK expression.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4165)
  AUTHORS   Drolet,D.W., Scully,K.M., Simmons,D.M., Wegner,M., Chu,K.T.,
            Swanson,L.W. and Rosenfeld,M.G.
  TITLE     TEF, a transcription factor expressed specifically in the anterior
            pituitary during embryogenesis, defines a new class of leucine
            zipper proteins
  JOURNAL   Genes Dev 5 (10), 1739-1753 (1991)
   PUBMED   1916262
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Nov 27, 2020 this sequence version replaced NM_019194.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC101895.1, SRR22582416.1023420.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-239               JAXUCZ010000007.1  115206827-115207065
            240-557             JAXUCZ010000007.1  115210255-115210572
            558-778             JAXUCZ010000007.1  115216276-115216496
            779-4165            JAXUCZ010000007.1  115218544-115221930
FEATURES             Location/Qualifiers
     source          1..4165
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..4165
                     /gene="Tef"
                     /note="TEF transcription factor, PAR bZIP family member"
                     /db_xref="GeneID:29362"
                     /db_xref="RGD:3841"
     exon            1..239
                     /gene="Tef"
                     /inference="alignment:Splign:2.1.0"
     CDS             89..994
                     /gene="Tef"
                     /note="thyrotrophic embryonic factor; TEF, PAR bZIP
                     transcription factor"
                     /codon_start=1
                     /product="thyrotroph embryonic factor"
                     /protein_id="NP_062067.2"
                     /db_xref="GeneID:29362"
                     /db_xref="RGD:3841"
                     /translation="MSEAGGGKKPPVEPQAGPGPGRAAGERGLSGSFPLVLKKLMENP
                     PRETRLDKEKGKEKLEEDESAAASTMAVSASLMPPIWDKTIPYDGESFHLEYMDLDEF
                     LLENGIPASPTHLAQNLLLPVAELEGKESASSSTASPPSSSTAIFQPSETVSSTESSL
                     EKERETPSPIDPNCVEVDVNFNPDPADLVLSSVPGGELFNPRKHKFAEEDLKPQPMIK
                     KAKKVFVPDEQKDEKYWTRRKKNNVAAKRSRDARRLKENQITIRAAFLEKENTALRTE
                     VAELRKEVGKCKTIVSKYETKYGPL"
     exon            240..557
                     /gene="Tef"
                     /inference="alignment:Splign:2.1.0"
     exon            558..778
                     /gene="Tef"
                     /inference="alignment:Splign:2.1.0"
     exon            779..4165
                     /gene="Tef"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcagcagct gcggcgggtc gagccgctcc ggcccatctc ggggtgcggg cgggggaggc
       61 gaggcgcacg agtggggcgc agggcacgat gtccgaggcg ggcggcggga agaagccgcc
      121 tgtggagcct caggcggggc cgggcccggg gcgtgcagct ggagaacggg gcctgtcggg
      181 ctccttccct ctagtcctga agaagctgat ggagaacccc ccgcgcgaga cgcggctcga
      241 taaggaaaag gggaaggaaa agctggagga agacgagtct gcagcagcca gtaccatggc
      301 cgtctctgcc tccctcatgc cacccatctg ggacaagaca atcccctacg atggcgagtc
      361 tttccaccta gagtacatgg acctggatga gttcctgttg gagaatggca tccctgccag
      421 ccccacccac ctggcccaga acctgctgct gcctgtggca gagcttgagg ggaaggagtc
      481 tgccagctct tccacagcat caccaccatc ttcctctact gccatcttcc agccctcgga
      541 aaccgtgtcc agcacagaat catccttgga aaaggagagg gagacaccaa gtcccatcga
      601 ccccaactgt gtggaggttg atgtgaactt caatcctgac cctgctgacc tggtcctctc
      661 tagtgtacca ggtggggaac ttttcaaccc tcggaagcac aagtttgcag aggaagacct
      721 gaagccccag cctatgatca agaaagccaa gaaagtcttt gtccctgatg agcagaagga
      781 tgagaagtac tggacaaggc gtaagaagaa caatgtggca gctaaacgct cccgggacgc
      841 caggcgcctg aaggagaatc agatcaccat ccgggcagca tttctggaga aggagaacac
      901 agccctgcgg acggaggttg ctgagcttcg caaggaggtg ggcaagtgca agaccatcgt
      961 gtccaagtat gagaccaagt acgggccctt gtaacctgtg ccccttgccc cgcagggcac
     1021 tgcctgcacc tcagacctct gcctggggct tcctggaccc cactcgtgtg gagacttagg
     1081 actcttcatg ggcacatggt ggcgtacctg ctctaggagc actcacgtct cagcttcatt
     1141 ataacatggc cagcacatgt ggtgacttcc ccaggggacc agggtcctct ctgatgggga
     1201 acatgagtga atctctgtag ccgggtaaat ggcccaagtc tcttgttgga tgctccggcg
     1261 gaatcagaag gggccttctg gagtccaggt tctcctgtac agagtgctca ggctttccta
     1321 gcctccctca gtctccagtt tggactgaca agggctgtct acagaatgag tcatgattat
     1381 tgtcacccta atgtcgtctc aggtagcagg tgcatttcca cttggggtgt gtctgtcatg
     1441 tacctcaccc tccccaaaaa aatctttgag agaaacattc attcccatct gtctcagaac
     1501 caggacatgc taatactctg ttagtgtata catggtggtg ggccacagaa gtggggtctc
     1561 tgcatagcct ggagttaggg tggggtgtgg ggcttgcagt agatatgcac ccaaccattc
     1621 ttagctccgg cttctatctt gtggctctca ggcctgaagc agccctggaa tcaatttcct
     1681 ctacatctca cttgctatgg aagaaaaatt cgcaggatgg ctgggctctg ggctctaatt
     1741 gccagcgcct ttgtacctct gggccattct ggaggctctt gacatccact agcctggtct
     1801 ctgattattg tcacccagta tcccttctca gaccttaagt ttaaaaagaa aacccatcac
     1861 ctaggaagct tgagcttcct agccccaggg taccacttct gcatggtgtt taggaaactg
     1921 gcctccagtc tcctgttgtg ggcaccagac tgagggcttt tctcttggga agctccatgg
     1981 aacccttgct ctggctcacc aatgtaccca gaccagaatc cagtctccct gaaggcagaa
     2041 gagggcctgt cacttcacag attagactcc ctcccttgag tatcagcagg tcgccttcta
     2101 tgagttgtat ttgctgaagg tacagctctc atgggacagc gggctctgga gacattacac
     2161 tggcctgcag tccgtctgga gtcagaaggt gcccacatag gtctgaccat tgggtagagt
     2221 gatttcttgc agctttggct ccctctgtgt cacagctgca cctttctctt ctatttggct
     2281 ggattggaaa tcatggaacc ctctgctcat gtgggtcagt tagggtgccc tccaggaggg
     2341 tgtgtttatt tgctcagggt gggcagcctg tgtgaaggag gcagaggtga tgagggtgct
     2401 ttattatact taacactggc tttattttaa atggtggctt agtttggggc cccaatcttt
     2461 taagactttt cataatgatg ttaagaccag ggcagactat ctactggcca tggactgcag
     2521 ccaggagatg ccctgcccct cctgggacct gcacaccacc tctctgggga acttgacaaa
     2581 ggtccctaag gctaagggag gtctccttcc tactaggtcc ctgactttga ctctgtggtt
     2641 ctctaggaac cgtgtgcaca cttgtctctg ttgtaaccac aaagggcagt agcacctagc
     2701 atgtcagtgt cctgccccgg ctgcttgcct cccacccacc caggacttct ctgggctggc
     2761 tgttcaccca gaggcagttc ctcattttgt tattggtgga caagccttga cctgaaaatc
     2821 tcttcgtttt ctttggctag gaaatgtaag gtttgtgttt tttaagtttt agttttaagg
     2881 aatagatact taactctgga tgccatctgt gttctgaccc tagtgggtgg atggggctta
     2941 ctgtctcccc gtggtcccct ctctgccttg tggtgccctc ctttccttcc agaagtaggt
     3001 aggggttctg gctcctccta aagtgcttac agaaacagtg tctgcttgct tcttggagga
     3061 gcctttggaa tgaaaaccgg cagggaaaca aaccagaagg agcatgtctg gaggttgaca
     3121 tcttggcgag aaaaaaaagt attcatgtaa gcttggctcc tccgttggcc ttaggaccca
     3181 aggctgcaca gaaagagttg atctctgctg ttgttttgct gtggaagcct cctgactccc
     3241 ctaggagctg acagcagaag cctgaagctc ctctcttgga tctttgaatt ctaaggaata
     3301 ccaggctcca gaagccaact tcagtttggc ttttcatggg tttgtcttgg gatgagaaat
     3361 gttgtcactt cctagacatc ctgttctcag ctatggcagc cgcagcaaag acacctgaat
     3421 gagttagaac cttgcaggaa tgtacattca agcgatgtgt ggaagaagaa ctacatgctt
     3481 ttggaaagag ccagctgtgg gggacccgct cggtcacctt agcctcagcc caataagtta
     3541 tgtgggtctg actcctgtgg ttggggacag cactagacag tgaacctaac tcttggtcca
     3601 cactctctgc tgagagggtg ctgtggtctg ctttccactc tggcagctcc tacagtcctc
     3661 cagcctgggg acagatgaga agcttgcttt ccaggggccc tgagaggtat gctccctggg
     3721 aggggcctgt aagtggagct cttggtttcc agggcaaagc cccacccaca gcttctttaa
     3781 catctgttaa ttaagtgcaa taaatttttc tagaaaaagg caaagatgat ttccaggtag
     3841 agattgctgt cgtttggtgt tggatgccgg aacaccactt ggttttattt ttctaagtgc
     3901 atgtgattgg tagagtgttt ggggctctgc atcctccctg ggagccgcat tccagcaacc
     3961 cctctcccta cctttgctgg gggaaggagg ccaggaggaa acccctttgt cccagctgta
     4021 gaggcggaag cagacagcag cccattggcc ttatgtgtgt gtgtgcctgt gcgtgtgtca
     4081 ctgctggtgg gccggagtga tgtggtaggg agggaaggtg ggaatgtatc cttttcaaac
     4141 aaaattaaat attttgagac gagaa
//
