LOCUS       NM_001098216            2576 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus TEA domain transcription factor 3 (Tead3), mRNA.
ACCESSION   NM_001098216 XM_001078363 XM_215356
VERSION     NM_001098216.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2576)
  AUTHORS   Feng G, Yi P, Yang Y, Chai Y, Tian D, Zhu Z, Liu J, Zhou F, Cheng
            Z, Wang X, Li W and Ou G.
  TITLE     Developmental stage-dependent transcriptional regulatory pathways
            control neuroblast lineage progression
  JOURNAL   Development 140 (18), 3838-3847 (2013)
   PUBMED   23946438
REFERENCE   2  (bases 1 to 2576)
  AUTHORS   Lian I, Kim J, Okazawa H, Zhao J, Zhao B, Yu J, Chinnaiyan A,
            Israel MA, Goldstein LS, Abujarour R, Ding S and Guan KL.
  TITLE     The role of YAP transcription coactivator in regulating stem cell
            self-renewal and differentiation
  JOURNAL   Genes Dev 24 (11), 1106-1118 (2010)
   PUBMED   20516196
REFERENCE   3  (bases 1 to 2576)
  AUTHORS   Zhang H, Liu CY, Zha ZY, Zhao B, Yao J, Zhao S, Xiong Y, Lei QY and
            Guan KL.
  TITLE     TEAD transcription factors mediate the function of TAZ in cell
            growth and epithelial-mesenchymal transition
  JOURNAL   J Biol Chem 284 (20), 13355-13362 (2009)
   PUBMED   19324877
  REMARK    Erratum:[J Biol Chem. 2019 Apr 12;294(15):5808. PMID: 30979850]
REFERENCE   4  (bases 1 to 2576)
  AUTHORS   Zhao B, Ye X, Yu J, Li L, Li W, Li S, Yu J, Lin JD, Wang CY,
            Chinnaiyan AM, Lai ZC and Guan KL.
  TITLE     TEAD mediates YAP-dependent gene induction and growth control
  JOURNAL   Genes Dev 22 (14), 1962-1971 (2008)
   PUBMED   18579750
REFERENCE   5  (bases 1 to 2576)
  AUTHORS   Sawada A, Nishizaki Y, Sato H, Yada Y, Nakayama R, Yamamoto S,
            Nishioka N, Kondoh H and Sasaki H.
  TITLE     Tead proteins activate the Foxa2 enhancer in the node in
            cooperation with a second factor
  JOURNAL   Development 132 (21), 4719-4729 (2005)
   PUBMED   16207754
REFERENCE   6  (bases 1 to 2576)
  AUTHORS   Yockey CE and Shimizu N.
  TITLE     cDNA cloning and characterization of mouse DTEF-1 and ETF, members
            of the TEA/ATTS family of transcription factors
  JOURNAL   DNA Cell Biol 17 (2), 187-196 (1998)
   PUBMED   9502435
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BC099077.1, BC085938.1 and
            BF418871.1.
            
            On or before May 25, 2007 this sequence version replaced
            XM_215356.4, XM_001078363.1.
            
            Summary: This gene product is a member of the transcriptional
            enhancer factor (TEF) family of transcription factors, which
            contain the TEA/ATTS DNA-binding domain. It is predominantly
            expressed in the placenta and thought to play a role in placental
            gene regulation and development. Translation of this protein is
            initiated at a non-AUG (AUA) start codon. [provided by RefSeq, Jul
            2008].
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC099077.1, BC085938.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            non-AUG initiation codon :: PMID: 10379887, 9671946
            RefSeq Select criteria   :: based on single protein-coding
                                        transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2153              BC099077.1         1-2153
            2154-2525           BC085938.1         2107-2478
            2526-2576           BF418871.1         1-51                c
FEATURES             Location/Qualifiers
     source          1..2576
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..2576
                     /gene="Tead3"
                     /note="TEA domain transcription factor 3"
                     /db_xref="GeneID:294299"
                     /db_xref="RGD:1311583"
     exon            1..189
                     /gene="Tead3"
                     /inference="alignment:Splign:2.1.0"
     exon            190..441
                     /gene="Tead3"
                     /inference="alignment:Splign:2.1.0"
     CDS             240..1553
                     /gene="Tead3"
                     /exception="alternative start codon"
                     /note="non-AUG (AUA) translation initiation codon; TEA
                     domain family member 3"
                     /codon_start=1
                     /transl_except=(pos:240..242,aa:Met)
                     /product="transcriptional enhancer factor TEF-5"
                     /protein_id="NP_001091686.1"
                     /db_xref="GeneID:294299"
                     /db_xref="RGD:1311583"
                     /translation="MASNSWTANNSPGEAREDGSEGLDKGLDNDAEGVWSPDIEQSFQ
                     EALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKV
                     REYQVGIKAMNLDQVSKDKALQSMASMSSAQIVSASVLQNKFSPPSPLPQAVFSTSRF
                     WSSPPLLGQQPGPSQDIKPFAQPAYPIQPPLPPTLNSYESLAPLPPAAATAASVPAWQ
                     DRTIASSRLRLLEYSAFMEVQRDPDTYSKHLFVHIGQTNPAFSDPPLEAVDVRQIYDK
                     FPEKKGGLKELYEKGPPNAFFLVKFWADLNSTIQEGPGAFYGVSSQYSSADSMTISVS
                     TKVCSFGKQVVEKVETEYARLENGRFVYRIHRSPMCEYMINFIHKLKHLPEKYMMNSV
                     LENFTILQVVTSRDSQETLLVIAFVFEVSTSEHGAQHHVYKLVKD"
     exon            442..506
                     /gene="Tead3"
                     /inference="alignment:Splign:2.1.0"
     exon            507..569
                     /gene="Tead3"
                     /inference="alignment:Splign:2.1.0"
     exon            570..581
                     /gene="Tead3"
                     /inference="alignment:Splign:2.1.0"
     exon            582..716
                     /gene="Tead3"
                     /inference="alignment:Splign:2.1.0"
     exon            717..766
                     /gene="Tead3"
                     /inference="alignment:Splign:2.1.0"
     exon            767..828
                     /gene="Tead3"
                     /inference="alignment:Splign:2.1.0"
     exon            829..971
                     /gene="Tead3"
                     /inference="alignment:Splign:2.1.0"
     exon            972..1145
                     /gene="Tead3"
                     /inference="alignment:Splign:2.1.0"
     exon            1146..1286
                     /gene="Tead3"
                     /inference="alignment:Splign:2.1.0"
     exon            1287..1439
                     /gene="Tead3"
                     /inference="alignment:Splign:2.1.0"
     exon            1440..2558
                     /gene="Tead3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2511..2516
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tead3"
     polyA_site      2540
                     /gene="Tead3"
     polyA_site      2558
                     /gene="Tead3"
ORIGIN      
        1 ggctccctca acacaaactt tccgtcccgc tcgctccctc ctccgcgccc agcacctccc
       61 gctccggccc ggctcattcc gtacattccg gccatccccc tgcccacgac cccccttccc
      121 ggcccccctt actactccct cgggcccggc ggagcggccc ggcggagcgc cccccggagc
      181 tcggagcagg ctcaggccat ccagggggct caggcccaga gcccagagca accagcacaa
      241 tagcgtccaa cagctggacc gccaacaaca gccccgggga ggcccgggaa gatgggtccg
      301 agggcctgga taaagggctg gacaacgatg ccgagggagt gtggagccca gacatcgagc
      361 agagctttca ggaggccctg gccatctacc cgccttgtgg ccggcgcaag atcatcctgt
      421 cggatgaggg caagatgtac ggtcgaaatg agctgattgc ccgatacatc aagctgagga
      481 ctggaaaaac caggacgaga aaacaggtgt ccagccacat acaggttcta gctcggaaga
      541 aggttcggga ataccaggtt ggcattaagg ctatgaacct ggaccaggtc tccaaggaca
      601 aagctcttca gagcatggca tctatgtcgt ctgcccaaat cgtctctgcc agcgtcctac
      661 agaacaagtt cagcccaccc tcccctctgc cccaggctgt cttctccacc tcaaggttct
      721 ggagcagccc ccctctgcta ggacaacagc ctggaccgtc tcaggacatc aagccctttg
      781 cacagcctgc ctaccccatc cagcctcccc tgccgccaac actcaatagt tatgagtccc
      841 tggccccgct gcccccagcc gctgccactg ctgcctccgt gcctgcctgg caggaccgca
      901 ccatcgcctc ctcccggcta cgcctcctgg agtattctgc cttcatggag gtgcaaaggg
      961 accccgacac gtacagcaaa cacctgtttg tacacatcgg ccagacaaac cctgccttct
     1021 cagacccacc cctggaggca gtggatgttc gccagatcta cgacaagttc cccgagaaga
     1081 aaggggggct gaaggagctc tacgagaaag ggccccccaa tgccttcttc cttgtcaagt
     1141 tctgggctga cctcaacagc acaatccagg aaggccctgg ggccttctac ggggtcagct
     1201 cacagtacag ctcggcggac agcatgacca tcagtgtctc caccaaggtg tgttccttcg
     1261 gcaagcaggt ggtagagaaa gtagagacag agtatgcccg cctggagaac ggccgctttg
     1321 tgtaccgcat ccaccgctca cccatgtgcg agtacatgat caacttcatc cacaagctga
     1381 agcacctgcc cgagaagtac atgatgaaca gcgtgctgga gaacttcacc atcctgcagg
     1441 tggtcacgag tcgggactcg caggagaccc tgctggtcat tgcttttgtc tttgaagtgt
     1501 ccaccagtga gcatggggca cagcatcacg tctacaagct tgtgaaagac tagcatgccc
     1561 acaggatgca agtcggacct cctccgaaca cctgcctgcc tggtctccct gggtgtgggt
     1621 tggggggacc tacccaccca tgggtttctt caggctggga cctgggctgc ctccctggcc
     1681 ccagcacaca cactccctgc cactgttctg cgctttactg gagagaagag ggctccacgg
     1741 tggggtggct tgcctgggca ctgagccata gatgacctgg cctcaggtga tatcagaatt
     1801 gtactatgga ggacaccttg ggggcttagt gtgttgtccc tggccactag aggagtgtga
     1861 tgggcaggag agagggtagc attaagacta ggaagagaca gcttgcaagg aggccctggt
     1921 acaaggtgtc aaattggggg ataggttgag aagggcctac acttcttcgg accttctggg
     1981 taccagcccc ttaacacagc aagtctgggt ctcctgaaag tgccaagatg gaggccccca
     2041 gaagcagaca gagctggagg ctgggttcag ctacctcccc agcagagctg ggtgctggca
     2101 gggaaggggc gtgctgtgga atggtacagc tgggctggag cctagacagg gttctacttc
     2161 ctgttctccc agtgtgctag ccactaggca cccctccctc catgtcctgc agacaggtgg
     2221 cagggaacag gaggctgcct ctgccttctc tacatccagg tcccaaggtc gcctgggtat
     2281 ttatgagttt caaatgaagt actgtgcccc tcctcatcca gcccgagctc cctgaaggtc
     2341 ttcaccattg catactgctc aggccacccc taaaccccac ctaggtttta tatcatgtat
     2401 tatatatatt tttgtgtatt tttaaaatcc agctgtgacg ggctatatcg taaatggctc
     2461 taaggcaggg gccactcaag gcctggctcc tgcttaaaaa aaaaaaaaaa attaaaaaaa
     2521 aaaaagctgt ttctgggtca ggacagttgt gccacatgaa aaaaaaaaaa aaaaaa
//
