LOCUS       NM_001107512            2135 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus TEA domain transcription factor 2 (Tead2), mRNA.
ACCESSION   NM_001107512 XM_001080702 XM_218630
VERSION     NM_001107512.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2135)
  AUTHORS   Tamm,C., Bower,N. and Anneren,C.
  TITLE     Regulation of mouse embryonic stem cell self-renewal by a
            Yes-YAP-TEAD2 signaling pathway downstream of LIF
  JOURNAL   J Cell Sci 124 (Pt 7), 1136-1144 (2011)
   PUBMED   21385842
REFERENCE   2  (bases 1 to 2135)
  AUTHORS   Tian,W., Yu,J., Tomchick,D.R., Pan,D. and Luo,X.
  TITLE     Structural and functional analysis of the YAP-binding domain of
            human TEAD2
  JOURNAL   Proc Natl Acad Sci U S A 107 (16), 7293-7298 (2010)
   PUBMED   20368466
REFERENCE   3  (bases 1 to 2135)
  AUTHORS   Bhattaram,P., Penzo-Mendez,A., Sock,E., Colmenares,C., Kaneko,K.J.,
            Vassilev,A., Depamphilis,M.L., Wegner,M. and Lefebvre,V.
  TITLE     Organogenesis relies on SoxC transcription factors for the survival
            of neural and mesenchymal progenitors
  JOURNAL   Nat Commun 1 (1), 9 (2010)
   PUBMED   20596238
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2135)
  AUTHORS   Zhang,H., Liu,C.Y., Zha,Z.Y., Zhao,B., Yao,J., Zhao,S., Xiong,Y.,
            Lei,Q.Y. and Guan,K.L.
  TITLE     TEAD transcription factors mediate the function of TAZ in cell
            growth and epithelial-mesenchymal transition
  JOURNAL   J Biol Chem 284 (20), 13355-13362 (2009)
   PUBMED   19324877
  REMARK    Erratum:[J Biol Chem. 2019 Apr 12;294(15):5808. doi:
            10.1074/jbc.AAC119.008436. PMID: 30979850]
REFERENCE   5  (bases 1 to 2135)
  AUTHORS   Zhao,B., Ye,X., Yu,J., Li,L., Li,W., Li,S., Yu,J., Lin,J.D.,
            Wang,C.Y., Chinnaiyan,A.M., Lai,Z.C. and Guan,K.L.
  TITLE     TEAD mediates YAP-dependent gene induction and growth control
  JOURNAL   Genes Dev 22 (14), 1962-1971 (2008)
   PUBMED   18579750
REFERENCE   6  (bases 1 to 2135)
  AUTHORS   Sawada,A., Nishizaki,Y., Sato,H., Yada,Y., Nakayama,R.,
            Yamamoto,S., Nishioka,N., Kondoh,H. and Sasaki,H.
  TITLE     Tead proteins activate the Foxa2 enhancer in the node in
            cooperation with a second factor
  JOURNAL   Development 132 (21), 4719-4729 (2005)
   PUBMED   16207754
REFERENCE   7  (bases 1 to 2135)
  AUTHORS   Kaneko,K.J., Rein,T., Guo,Z.S., Latham,K. and DePamphilis,M.L.
  TITLE     DNA methylation may restrict but does not determine differential
            gene expression at the Sgy/Tead2 locus during mouse development
  JOURNAL   Mol Cell Biol 24 (5), 1968-1982 (2004)
   PUBMED   14966277
REFERENCE   8  (bases 1 to 2135)
  AUTHORS   Milewski,R.C., Chi,N.C., Li,J., Brown,C., Lu,M.M. and Epstein,J.A.
  TITLE     Identification of minimal enhancer elements sufficient for Pax3
            expression in neural crest and implication of Tead2 as a regulator
            of Pax3
  JOURNAL   Development 131 (4), 829-837 (2004)
   PUBMED   14736747
  REMARK    Erratum:[Development. 2004 Mar;131(5):1195]
REFERENCE   9  (bases 1 to 2135)
  AUTHORS   Yockey,C.E. and Shimizu,N.
  TITLE     cDNA cloning and characterization of mouse DTEF-1 and ETF, members
            of the TEA/ATTS family of transcription factors
  JOURNAL   DNA Cell Biol 17 (2), 187-196 (1998)
   PUBMED   9502435
REFERENCE   10 (bases 1 to 2135)
  AUTHORS   Yasunami,M., Suzuki,K., Houtani,T., Sugimoto,T. and Ohkubo,H.
  TITLE     Molecular characterization of cDNA encoding a novel protein related
            to transcriptional enhancer factor-1 from neural precursor cells
  JOURNAL   J Biol Chem 270 (31), 18649-18654 (1995)
   PUBMED   7629195
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473979.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_218630.4, XM_001080702.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            CDS exon combination :: BC168947.1 [ECO:0000331]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2135
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..2135
                     /gene="Tead2"
                     /note="TEA domain transcription factor 2"
                     /db_xref="GeneID:308582"
                     /db_xref="RGD:1593252"
     exon            1..110
                     /gene="Tead2"
                     /inference="alignment:Splign:2.1.0"
     exon            111..348
                     /gene="Tead2"
                     /inference="alignment:Splign:2.1.0"
     CDS             117..1454
                     /gene="Tead2"
                     /note="Embryonic TEA domain containing factor; TEA domain
                     family member 2"
                     /codon_start=1
                     /product="transcriptional enhancer factor TEF-4"
                     /protein_id="NP_001100982.1"
                     /db_xref="GeneID:308582"
                     /db_xref="RGD:1593252"
                     /translation="MGDPRTGAPLDDGGGWTGSEEGSEEGTGGSEGVGGDGSPDAEGV
                     WSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSS
                     HIQVLARRKSREIQSKLKDQVSKDKAFQTMATMSSAQLISAPSLQAKLGPSGPQATEL
                     FQFWSGSSGPTWNVPDVKPFSQAPFSMSLTPPATDLPGYEPPPALSPLPPPAPSPPAW
                     QARALGTARLQLVEFSAFVEPPDAVDSFQRHLFVHISQQCPSPGAPPLESVDVRQIYD
                     KFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSAEEAGNSGGAGGFYGVSSQYESR
                     ELMTLTCSSKVCSFGKQVVEKVETERAQLEGGRFVYRLLRSPMCEYLVNFLHKLRQLP
                     ERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERGAQHHIYRLVRD"
     exon            349..413
                     /gene="Tead2"
                     /inference="alignment:Splign:2.1.0"
     exon            414..476
                     /gene="Tead2"
                     /inference="alignment:Splign:2.1.0"
     exon            477..584
                     /gene="Tead2"
                     /inference="alignment:Splign:2.1.0"
     exon            585..643
                     /gene="Tead2"
                     /inference="alignment:Splign:2.1.0"
     exon            644..708
                     /gene="Tead2"
                     /inference="alignment:Splign:2.1.0"
     exon            709..851
                     /gene="Tead2"
                     /inference="alignment:Splign:2.1.0"
     exon            852..1025
                     /gene="Tead2"
                     /inference="alignment:Splign:2.1.0"
     exon            1026..1187
                     /gene="Tead2"
                     /inference="alignment:Splign:2.1.0"
     exon            1188..1340
                     /gene="Tead2"
                     /inference="alignment:Splign:2.1.0"
     exon            1341..2135
                     /gene="Tead2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcttgggctc tttgttctgt cctccagatg gctgggcgac tgagtcccaa ggcctgaagt
       61 ttgatgggcg ccccagcccc gcctccacct ggttctgtgg ttactttctg gcccagatgg
      121 gggatccccg gactggggcc cccctggatg atggcggggg ctggacaggt agtgaggaag
      181 gcagcgagga gggcactgga ggcagtgaag gtgttggagg tgatgggagc cccgatgcag
      241 aaggtgtgtg gagccctgac atcgagcaga gttttcagga ggccctggca atctaccctc
      301 cctgtggccg tcgcaagatc atcttgtcag atgagggcaa gatgtatggc cggaacgaac
      361 tcatcgcccg ttacatcaag ctgaggacag ggaagaccag aactcgaaag caggtctcta
      421 gtcacatcca ggttttggct cgaaggaaat cgagagaaat tcagtccaag ctgaaggacc
      481 aagtctccaa ggacaaggcc ttccagacga tggccaccat gtcttcggca cagctcatct
      541 ctgcaccttc tctccaggcc aagctgggtc cttctggccc tcaggccacc gagcttttcc
      601 agttctggtc agggagctct gggccaacat ggaatgttcc agacgtgaag cccttctcac
      661 aagcaccgtt ctccatgtca ctgacgcccc cagccactga cctaccaggg tacgagccgc
      721 ccccagccct ctcaccccta cccccacccg ccccatctcc cccagcctgg caggctcggg
      781 ccctgggcac tgcgcgcctg cagctggtag agttctcagc gtttgtggag ccgccagatg
      841 cagttgactc gttccagagg catctgtttg tccacatcag tcagcagtgc cccagccctg
      901 gagccccacc cctggagagt gtggacgtgc ggcagatcta cgacaaattc cctgagaaaa
      961 agggcggtct ccgggagctg tatgaccggg ggccaccaca tgcctttttc ctggtcaagt
     1021 tctgggcgga cctgaactgg ggcccaagtg ccgaggaggc agggaacagc ggaggtgctg
     1081 gtggcttcta cggagtgagc agccagtacg agagccgaga gctcatgaca ctgacctgct
     1141 cctccaaggt ctgctccttt ggcaagcaag tggtggagaa ggtggagaca gagcgggccc
     1201 agctggaggg cgggcgcttt gtgtaccgcc tgctgcgctc tcccatgtgt gagtacctgg
     1261 tcaacttcct gcacaagctc cgtcagctgc ctgagcgcta catgatgaac agcgtcctgg
     1321 agaacttcac catcctccag gttgtgacaa atagggacac tcaggaactg ctgctgtgta
     1381 ctgcctacgt ctttgaagtc tccaccagtg aacgcggagc ccagcaccac atctaccgcc
     1441 tggtcaggga ctgatggggc cccattgctg ctgtttatcc gaacaccccc ttcctaggaa
     1501 gggcccttct gctctccctg taagagagat gtggagaggg gcccatgatt tttaaaaagg
     1561 cctcatctca gaagcaatgg gggctggctt ctattagaaa ggcacccgaa gcttggcagc
     1621 gaagggagct gggtttgagt ttagatcccc aacacgagga cctcacagag aacctttgac
     1681 aggacacacc actcctgagc atcagggatt gaggatagga gtgcatgcgc acaggtacgc
     1741 ggcctctcca ctctacaggg gcccctcctt gctcttctgg aaaggggagc tcagctatgt
     1801 ggggcctctt actcattgcc ttataccctt cctgttttcc agtggtctca tgtctgcccc
     1861 tcccccacac cctttctctg ggatctgtaa tgttacaaac cgaagataat ggtttcccag
     1921 cttgaggtag agtgaagtgg gacctgaaaa attgttttaa tataaggaga tatttataca
     1981 cagtgttagg gatgtaatct tatctcagct aggcagtggg gtgggacttc ttaatctccc
     2041 cccaccccat tcaagtgagc cgtggaccac cctgccacct tcccttcccc aagagtgatg
     2101 gtttatgttt gaaggagaat aaaactattt ttacc
//
