LOCUS       NM_001198589            1564 bp    mRNA    linear   ROD 15-JAN-2025
DEFINITION  Rattus norvegicus TEA domain transcription factor 1 (Tead1),
            transcript variant 1, mRNA.
ACCESSION   NM_001198589 XM_001069402 XM_001069451 XM_001078008
VERSION     NM_001198589.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1564)
  AUTHORS   Kusumanchi,P., Liang,T., Zhang,T., Ross,R.A., Han,S., Chandler,K.,
            Oshodi,A., Jiang,Y., Dent,A.L., Skill,N.J., Huda,N., Ma,J., Yang,Z.
            and Liangpunsakul,S.
  TITLE     Stress-Responsive Gene FK506-Binding Protein 51 Mediates
            Alcohol-Induced Liver Injury Through the Hippo Pathway and
            Chemokine (C-X-C Motif) Ligand 1 Signaling
  JOURNAL   Hepatology 74 (3), 1234-1250 (2021)
   PUBMED   33710653
REFERENCE   2  (bases 1 to 1564)
  AUTHORS   Zhang,T., Li,W., Qiu,X., Liu,B., Li,G., Feng,C., Liao,J. and Lin,K.
  TITLE     [CRISPR/Cas9-mediated TEAD1 knockout induces phenotypic modulation
            of corpus cavernosum smooth muscle cells in diabetic rats with
            erectile dysfunction]
  JOURNAL   Nan Fang Yi Ke Da Xue Xue Bao 41 (4), 567-573 (2021)
   PUBMED   33963717
  REMARK    GeneRIF: [CRISPR/Cas9-mediated TEAD1 knockout induces phenotypic
            modulation of corpus cavernosum smooth muscle cells in diabetic
            rats with erectile dysfunction].
REFERENCE   3  (bases 1 to 1564)
  AUTHORS   Simile,M.M., Latte,G., Demartis,M.I., Brozzetti,S., Calvisi,D.F.,
            Porcu,A., Feo,C.F., Seddaiu,M.A., Daino,L., Berasain,C.,
            Tomasi,M.L., Avila,M.A., Feo,F. and Pascale,R.M.
  TITLE     Post-translational deregulation of YAP1 is genetically controlled
            in rat liver cancer and determines the fate and stem-like behavior
            of the human disease
  JOURNAL   Oncotarget 7 (31), 49194-49216 (2016)
   PUBMED   27359056
  REMARK    GeneRIF: Yap1 post-translational modifications favoring its
            ubiquitination and apoptosis characterize hepatocellular carcinoma
            (HCC) with better prognosis, whereas conditions favoring the
            formation of YAP1-TEAD complexes are associated with aggressiveness
            and acquisition of stemness features by HCC cells
REFERENCE   4  (bases 1 to 1564)
  AUTHORS   Lopez-Anido,C., Poitelon,Y., Gopinath,C., Moran,J.J., Ma,K.H.,
            Law,W.D., Antonellis,A., Feltri,M.L. and Svaren,J.
  TITLE     Tead1 regulates the expression of Peripheral Myelin Protein 22
            during Schwann cell development
  JOURNAL   Hum Mol Genet 25 (14), 3055-3069 (2016)
   PUBMED   27288457
REFERENCE   5  (bases 1 to 1564)
  AUTHORS   Yu,C., Ji,S.Y., Dang,Y.J., Sha,Q.Q., Yuan,Y.F., Zhou,J.J.,
            Yan,L.Y., Qiao,J., Tang,F. and Fan,H.Y.
  TITLE     Oocyte-expressed yes-associated protein is a key activator of the
            early zygotic genome in mouse
  JOURNAL   Cell Res 26 (3), 275-287 (2016)
   PUBMED   26902285
REFERENCE   6  (bases 1 to 1564)
  AUTHORS   Gunther,S., Mielcarek,M., Kruger,M. and Braun,T.
  TITLE     VITO-1 is an essential cofactor of TEF1-dependent muscle-specific
            gene regulation
  JOURNAL   Nucleic Acids Res 32 (2), 791-802 (2004)
   PUBMED   14762206
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 1564)
  AUTHORS   Karasseva,N., Tsika,G., Ji,J., Zhang,A., Mao,X. and Tsika,R.
  TITLE     Transcription enhancer factor 1 binds multiple muscle MEF2 and
            A/T-rich elements during fast-to-slow skeletal muscle fiber type
            transitions
  JOURNAL   Mol Cell Biol 23 (15), 5143-5164 (2003)
   PUBMED   12861002
  REMARK    GeneRIF: Transcription enhancer factor 1 (Tef-1)binds multiple
            muscle MEF2 and A/T-rich elements during fast-to-slow skeletal
            muscle fiber type transitions.
REFERENCE   8  (bases 1 to 1564)
  AUTHORS   O'Connell,T.D., Rokosh,D.G. and Simpson,P.C.
  TITLE     Cloning and characterization of the mouse alpha1C/A-adrenergic
            receptor gene and analysis of an alpha1C promoter in cardiac
            myocytes: role of an MCAT element that binds transcriptional
            enhancer factor-1 (TEF-1)
  JOURNAL   Mol Pharmacol 59 (5), 1225-1234 (2001)
   PUBMED   11306707
REFERENCE   9  (bases 1 to 1564)
  AUTHORS   Zuzarte,P.C., Farrance,I.K., Simpson,P.C. and Wildeman,A.G.
  TITLE     Tumor cell splice variants of the transcription factor TEF-1
            induced by SV40 T-antigen transformation
  JOURNAL   Biochim Biophys Acta 1517 (1), 82-90 (2000)
   PUBMED   11118619
REFERENCE   10 (bases 1 to 1564)
  AUTHORS   Chen,Z., Friedrich,G.A. and Soriano,P.
  TITLE     Transcriptional enhancer factor 1 disruption by a retroviral gene
            trap leads to heart defects and embryonic lethality in mice
  JOURNAL   Genes Dev 8 (19), 2293-2301 (1994)
   PUBMED   7958896
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Feb 10, 2021 this sequence version replaced NM_001198589.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            CDS exon combination :: AY529195.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMEA5760386, SAMN06621351 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-217               JAXUCZ010000001.1  176227175-176227391
            218-473             JAXUCZ010000001.1  176300367-176300622
            474-538             JAXUCZ010000001.1  176382111-176382175
            539-601             JAXUCZ010000001.1  176384720-176384782
            602-613             JAXUCZ010000001.1  176397751-176397762
            614-748             JAXUCZ010000001.1  176398545-176398679
            749-795             JAXUCZ010000001.1  176399551-176399597
            796-857             JAXUCZ010000001.1  176400429-176400490
            858-982             JAXUCZ010000001.1  176402222-176402346
            983-1156            JAXUCZ010000001.1  176415713-176415886
            1157-1297           JAXUCZ010000001.1  176429832-176429972
            1298-1450           JAXUCZ010000001.1  176432667-176432819
            1451-1564           JAXUCZ010000001.1  176437084-176437197
FEATURES             Location/Qualifiers
     source          1..1564
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q33"
     gene            1..1564
                     /gene="Tead1"
                     /gene_synonym="TEF-1"
                     /note="TEA domain transcription factor 1"
                     /db_xref="GeneID:361630"
                     /db_xref="RGD:1549742"
     exon            1..217
                     /gene="Tead1"
                     /gene_synonym="TEF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            218..473
                     /gene="Tead1"
                     /gene_synonym="TEF-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             317..1564
                     /gene="Tead1"
                     /gene_synonym="TEF-1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     transcriptional enhancer factor TEF-1; TEA domain family
                     member 1"
                     /codon_start=1
                     /product="transcriptional enhancer factor TEF-1 isoform 1"
                     /protein_id="NP_001185518.1"
                     /db_xref="GeneID:361630"
                     /db_xref="RGD:1549742"
                     /translation="MERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKII
                     LSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKVTSMDQT
                     AKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGGPGFWPGMIQTGQPGSSQD
                     VKPFVQQAYPIQPAVTAPIPGFEPASAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQR
                     DPDSYNKHLFVHIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFL
                     VKFWADLNCNIQDDAGAFYGVSSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFE
                     NGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCM
                     ACVFEVSNSEHGAQHHIYRLVKD"
     exon            474..538
                     /gene="Tead1"
                     /gene_synonym="TEF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            539..601
                     /gene="Tead1"
                     /gene_synonym="TEF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            602..613
                     /gene="Tead1"
                     /gene_synonym="TEF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            614..748
                     /gene="Tead1"
                     /gene_synonym="TEF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            749..795
                     /gene="Tead1"
                     /gene_synonym="TEF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            796..857
                     /gene="Tead1"
                     /gene_synonym="TEF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            858..982
                     /gene="Tead1"
                     /gene_synonym="TEF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            983..1156
                     /gene="Tead1"
                     /gene_synonym="TEF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1157..1297
                     /gene="Tead1"
                     /gene_synonym="TEF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1298..1450
                     /gene="Tead1"
                     /gene_synonym="TEF-1"
                     /inference="alignment:Splign:2.1.0"
     exon            1451..1564
                     /gene="Tead1"
                     /gene_synonym="TEF-1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggccgcgg cggggcgcag gccatgcgct gaccccccag cgcgcaacgt cgccggagcg
       61 cgggcagctg ccccggcgcg ccctgctggt ccggggagcc ggcgaggccg ggctggggcg
      121 gccgggcgcg ggagtaccgc ggggagtacc ggctggagta gcgcgggggc ggtggcccag
      181 cgccccgaag tttgccgcgc ccgctcgggc ggccgaggtt tgctttcttg aaaaggctcc
      241 aggcttcggc ttggaaaatc caaccgccaa gattgagccg agcagctgga gcggcagcga
      301 gagccctgcc gacaacatgg agaggatgag tgactcggca gacaagccga ttgacaacga
      361 cgcagagggg gtctggagtc cggacattga gcagagtttc caggaggccc tggctatcta
      421 tccgccctgt gggaggagga aaatcatctt atcagacgaa ggcaaaatgt atggtagaaa
      481 tgaattgata gccagataca tcaaactgag gacgggaaag acaaggacta ggaagcaggt
      541 gtctagtcac attcaggttc ttgccagaag gaaatctcgt gattttcatt ccaagctaaa
      601 ggtaacaagc atggatcaga ctgccaagga caaggccctg cagcacatgg ctgccatgtc
      661 atcagcccag atcgtctcag ctaccgccat ccacaacaag ctgggactgc ctgggattcc
      721 ccgccccacc ttcccagggg gcccggggtt ctggcctggg atgatacaga caggacagcc
      781 aggatcctca caagacgtca agccctttgt gcagcaggcc taccccatcc agccagcagt
      841 cacagccccc attccagggt ttgagcctgc atcagcccca gctccctcag ttcctgcctg
      901 gcagggccga tccattggca caaccaagct tcgcctggtg gaattctcag ctttccttga
      961 gcagcagaga gacccagact cgtacaacaa acacctcttc gtgcacatcg ggcatgccaa
     1021 ccattcttac agcgacccgt tgctcgaatc cgtggacatt cgtcagatat atgacaaatt
     1081 tcctgaaaag aaaggtggct tgaaagaact gtttggaaag ggccctcaaa acgccttctt
     1141 ccttgtcaaa ttctgggcgg acttaaactg caatatccaa gatgacgccg gggcctttta
     1201 tggtgtgagc agtcaatacg agagttctga aaacatgaca gttacctgtt ccaccaaagt
     1261 gtgctccttt gggaaacaag tagtagaaaa agtagagacg gagtatgcga ggttcgagaa
     1321 tggccgattc gtgtaccgaa taaaccgctc accaatgtgt gaatatatga tcaacttcat
     1381 ccacaagctt aaacacctac cagagaaata tatgatgaac agcgttttgg aaaacttcac
     1441 cattttattg gtggtaacaa acagggatac acaagagact ctgctctgca tggcctgtgt
     1501 gtttgaagta tcgaatagtg agcatggagc acagcatcac atctacaggc ttgtaaagga
     1561 ctga
//
