LOCUS       NM_001014038            1970 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus tudor and KH domain containing (Tdrkh), mRNA.
ACCESSION   NM_001014038 XM_347211
VERSION     NM_001014038.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1970)
  AUTHORS   Saxe,J.P., Chen,M., Zhao,H. and Lin,H.
  TITLE     Tdrkh is essential for spermatogenesis and participates in primary
            piRNA biogenesis in the germline
  JOURNAL   EMBO J 32 (13), 1869-1885 (2013)
   PUBMED   23714778
REFERENCE   2  (bases 1 to 1970)
  AUTHORS   Chen,C., Jin,J., James,D.A., Adams-Cioaba,M.A., Park,J.G., Guo,Y.,
            Tenaglia,E., Xu,C., Gish,G., Min,J. and Pawson,T.
  TITLE     Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor
            domain to arginine methylated Miwi
  JOURNAL   Proc Natl Acad Sci U S A 106 (48), 20336-20341 (2009)
   PUBMED   19918066
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Mar 16, 2010 this sequence version replaced NM_001014038.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643293.13165.1,
                                           SRR26360194.1298524.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-90                JAXUCZ010000002.1  184738247-184738336
            91-240              JAXUCZ010000002.1  184751770-184751919
            241-347             JAXUCZ010000002.1  184752639-184752745
            348-537             JAXUCZ010000002.1  184753452-184753641
            538-677             JAXUCZ010000002.1  184754508-184754647
            678-999             JAXUCZ010000002.1  184754741-184755062
            1000-1160           JAXUCZ010000002.1  184756827-184756987
            1161-1333           JAXUCZ010000002.1  184757124-184757296
            1334-1398           JAXUCZ010000002.1  184757444-184757508
            1399-1550           JAXUCZ010000002.1  184758131-184758282
            1551-1652           JAXUCZ010000002.1  184758426-184758527
            1653-1749           JAXUCZ010000002.1  184759086-184759182
            1750-1970           JAXUCZ010000002.1  184759565-184759785
FEATURES             Location/Qualifiers
     source          1..1970
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..1970
                     /gene="Tdrkh"
                     /gene_synonym="RGD1311196"
                     /note="tudor and KH domain containing"
                     /db_xref="GeneID:310652"
                     /db_xref="RGD:1311196"
     exon            1..90
                     /gene="Tdrkh"
                     /gene_synonym="RGD1311196"
                     /inference="alignment:Splign:2.1.0"
     exon            91..240
                     /gene="Tdrkh"
                     /gene_synonym="RGD1311196"
                     /inference="alignment:Splign:2.1.0"
     CDS             117..1799
                     /gene="Tdrkh"
                     /gene_synonym="RGD1311196"
                     /codon_start=1
                     /product="tudor and KH domain-containing protein"
                     /protein_id="NP_001014060.2"
                     /db_xref="GeneID:310652"
                     /db_xref="RGD:1311196"
                     /translation="MSTERTSWTNLSTIQKIALGLGIPASATVAYILYRRYRESREER
                     LTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLIS
                     GFPVQVCKAKAAIHQILTENTPVFEQLSVPQRSVGRIIGRGGETIRSICKASGAKITC
                     DKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPI
                     SVRREEVTEPGGAGEAALWKNTNSSMGPAAPLEVPLRKGGGDMVVVGPKEGSWEKPND
                     DSFQNSGAQSSPETSMFEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIIGSRSLQLD
                     KLVSEMTQHYENSLPEDLTVHVGDIVAAPLSTNGSWYRARVLGTLENGNLDLYFVDFG
                     DNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGEEWEEEALDEFDRLTHCADWKP
                     LVAKISSYVQTGISTWPKVYLYDTSNGKKLDIGLELVRKGYAVELPEDMEENRTVPDM
                     LKDMATETDDSLASILTETKKSPEEIPHTLSCLSLSEAASMSGDDNLEDDLF"
     exon            241..347
                     /gene="Tdrkh"
                     /gene_synonym="RGD1311196"
                     /inference="alignment:Splign:2.1.0"
     exon            348..537
                     /gene="Tdrkh"
                     /gene_synonym="RGD1311196"
                     /inference="alignment:Splign:2.1.0"
     exon            538..677
                     /gene="Tdrkh"
                     /gene_synonym="RGD1311196"
                     /inference="alignment:Splign:2.1.0"
     exon            678..999
                     /gene="Tdrkh"
                     /gene_synonym="RGD1311196"
                     /inference="alignment:Splign:2.1.0"
     exon            1000..1160
                     /gene="Tdrkh"
                     /gene_synonym="RGD1311196"
                     /inference="alignment:Splign:2.1.0"
     exon            1161..1333
                     /gene="Tdrkh"
                     /gene_synonym="RGD1311196"
                     /inference="alignment:Splign:2.1.0"
     exon            1334..1398
                     /gene="Tdrkh"
                     /gene_synonym="RGD1311196"
                     /inference="alignment:Splign:2.1.0"
     exon            1399..1550
                     /gene="Tdrkh"
                     /gene_synonym="RGD1311196"
                     /inference="alignment:Splign:2.1.0"
     exon            1551..1652
                     /gene="Tdrkh"
                     /gene_synonym="RGD1311196"
                     /inference="alignment:Splign:2.1.0"
     exon            1653..1749
                     /gene="Tdrkh"
                     /gene_synonym="RGD1311196"
                     /inference="alignment:Splign:2.1.0"
     exon            1750..1970
                     /gene="Tdrkh"
                     /gene_synonym="RGD1311196"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctaggcggc tgcgccgagg gagcgacggg gcggcggcgg tgcgggtgag gtgcgaggcg
       61 aagcgcgcag cgtgcaactc tggaggagcg gatgttaagt cggagtacag cagaaaatgt
      121 ccaccgaacg aacttcatgg acaaacctgt ccactattca gaaaatagcc ctgggcctgg
      181 gaattccagc aagtgcgaca gttgcctaca tcctgtatcg tcgatacagg gaaagtagag
      241 aagagagatt gacatttgtt ggagaagatg acattgaaat agagatgcga gttccccaag
      301 aagctgtgaa gctcatcatt ggtcgacaag gagccaatat taaacagctg cggaagcaga
      361 caggtgctcg gattgatgtg gacacggagg atgtaggcga tgagcgggtg ctgctgatca
      421 gtggttttcc tgttcaggtg tgcaaggcca aagcagcaat ccatcaaatc ctgacagaga
      481 acaccccagt gtttgagcaa ctctctgtcc cccagagatc tgtgggcaga atcataggga
      541 gaggcggtga gaccattcgt tctatctgta aggcttctgg agccaaaatc acttgcgaca
      601 aggaatcaga gggaacatta ctactctcac gacttataaa aatctcagga acacagaagg
      661 aagtggctgc agccaagcat ctgatactgg agaaagtttc agaagatgag gaacttcgga
      721 agagaattgc ccattctgca gaaaccagag tcccccgaaa gcagccaatc agcgtgagaa
      781 gagaggaagt gacagagcct ggtggagctg gagaagcagc tttatggaaa aatacaaatt
      841 ctagcatggg accagctgca cccctggaag ttcctctccg caaaggaggt ggtgatatgg
      901 ttgttgtagg accaaaagaa ggttcctggg agaaacctaa tgatgacagc tttcagaatt
      961 ctggtgccca gagcagtcca gagacgtcta tgtttgaaat tcccagtcct gacttcagtt
     1021 tccatgctga tgagtaccta gaagtctacg tttctgcttc tgaacaccct aaccacttct
     1081 ggatccagat cattggttcc cgcagcctac agttggataa acttgtcagt gagatgaccc
     1141 agcactatga gaatagtctg cctgaagacc tgactgtgca tgtaggagac attgtagcag
     1201 cacccttatc tacaaatggt tcctggtatc gagcccgggt tctgggaacc ttggaaaatg
     1261 gaaacttgga cctctacttt gttgactttg gagataatgg agattgccca ctaaaggatc
     1321 tcagggctct caggagtgac tttctaagtc tcccatttca agcaatagaa tgcagtctgg
     1381 cacggattgc cccctcaggt gaagagtggg aagaggaagc tctagatgag tttgacagac
     1441 tcactcactg tgctgactgg aagcccctgg tggccaagat ttctagctat gtccagactg
     1501 gaatttcaac ttggccaaag gtctatttat atgataccag caatggaaag aaacttgata
     1561 ttgggctaga attagttcgt aaaggatatg cagttgaact tcctgaagac atggaagaaa
     1621 atagaactgt cccagatatg ttgaaggaca tggccacaga aacagatgat tctcttgcaa
     1681 gcatactcac tgagacaaaa aagagccctg aagagatacc acataccctg tcctgcctca
     1741 gcttatcaga agctgcctct atgtctggtg atgataacct tgaagatgac ttattctgaa
     1801 atttgggctt cagctgctgg atcagccatc tgctttgctg tgtgagtggt gctgtcatct
     1861 gtctgtagca acaggaaagt agtgggggtg acaacaccct cttccctgtg ctcctacgtg
     1921 tgtacatttg tctgccgcat ctttgatgca gcttaacctg ctctcagtcc
//
