LOCUS       NM_001419577            4861 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus tudor domain containing 9 (Tdrd9), mRNA.
ACCESSION   NM_001419577 XM_008764986
VERSION     NM_001419577.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4861)
  AUTHORS   Arafat,M., Har-Vardi,I., Harlev,A., Levitas,E., Zeadna,A.,
            Abofoul-Azab,M., Dyomin,V., Sheffield,V.C., Lunenfeld,E.,
            Huleihel,M. and Parvari,R.
  TITLE     Mutation in TDRD9 causes non-obstructive azoospermia in infertile
            men
  JOURNAL   J Med Genet 54 (9), 633-639 (2017)
   PUBMED   28536242
REFERENCE   2  (bases 1 to 4861)
  AUTHORS   Wenda,J.M., Homolka,D., Yang,Z., Spinelli,P., Sachidanandam,R.,
            Pandey,R.R. and Pillai,R.S.
  TITLE     Distinct Roles of RNA Helicases MVH and TDRD9 in PIWI
            Slicing-Triggered Mammalian piRNA Biogenesis and Function
  JOURNAL   Dev Cell 41 (6), 623-637 (2017)
   PUBMED   28633017
REFERENCE   3  (bases 1 to 4861)
  AUTHORS   Inoue,H., Ogonuki,N., Hirose,M., Hatanaka,Y., Matoba,S., Chuma,S.,
            Kobayashi,K., Wakana,S., Noguchi,J., Inoue,K., Tanemura,K. and
            Ogura,A.
  TITLE     Mouse D1Pas1, a DEAD-box RNA helicase, is required for the
            completion of first meiotic prophase in male germ cells
  JOURNAL   Biochem Biophys Res Commun 478 (2), 592-598 (2016)
   PUBMED   27473657
REFERENCE   4  (bases 1 to 4861)
  AUTHORS   Shoji,M., Tanaka,T., Hosokawa,M., Reuter,M., Stark,A., Kato,Y.,
            Kondoh,G., Okawa,K., Chujo,T., Suzuki,T., Hata,K., Martin,S.L.,
            Noce,T., Kuramochi-Miyagawa,S., Nakano,T., Sasaki,H., Pillai,R.S.,
            Nakatsuji,N. and Chuma,S.
  TITLE     The TDRD9-MIWI2 complex is essential for piRNA-mediated
            retrotransposon silencing in the mouse male germline
  JOURNAL   Dev Cell 17 (6), 775-787 (2009)
   PUBMED   20059948
REFERENCE   5  (bases 1 to 4861)
  AUTHORS   Aravin,A.A., van der Heijden,G.W., Castaneda,J., Vagin,V.V.,
            Hannon,G.J. and Bortvin,A.
  TITLE     Cytoplasmic compartmentalization of the fetal piRNA pathway in mice
  JOURNAL   PLoS Genet 5 (12), e1000764 (2009)
   PUBMED   20011505
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Apr 12, 2023 this sequence version replaced XM_008764986.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643293.37635.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-305               JAXUCZ010000006.1  136850812-136851116
            306-412             JAXUCZ010000006.1  136873977-136874083
            413-510             JAXUCZ010000006.1  136881401-136881498
            511-732             JAXUCZ010000006.1  136884938-136885159
            733-855             JAXUCZ010000006.1  136885638-136885760
            856-936             JAXUCZ010000006.1  136888070-136888150
            937-1101            JAXUCZ010000006.1  136889116-136889280
            1102-1205           JAXUCZ010000006.1  136894744-136894847
            1206-1270           JAXUCZ010000006.1  136902641-136902705
            1271-1325           JAXUCZ010000006.1  136909532-136909586
            1326-1410           JAXUCZ010000006.1  136909728-136909812
            1411-1468           JAXUCZ010000006.1  136910632-136910689
            1469-1573           JAXUCZ010000006.1  136912001-136912105
            1574-1671           JAXUCZ010000006.1  136915116-136915213
            1672-1803           JAXUCZ010000006.1  136916443-136916574
            1804-1969           JAXUCZ010000006.1  136917226-136917391
            1970-2033           JAXUCZ010000006.1  136917479-136917542
            2034-2097           JAXUCZ010000006.1  136917612-136917675
            2098-2142           JAXUCZ010000006.1  136917962-136918006
            2143-2196           JAXUCZ010000006.1  136918686-136918739
            2197-2313           JAXUCZ010000006.1  136923873-136923989
            2314-2421           JAXUCZ010000006.1  136925550-136925657
            2422-2522           JAXUCZ010000006.1  136926978-136927078
            2523-2696           JAXUCZ010000006.1  136928278-136928451
            2697-2808           JAXUCZ010000006.1  136931361-136931472
            2809-3021           JAXUCZ010000006.1  136934059-136934271
            3022-3111           JAXUCZ010000006.1  136935257-136935346
            3112-3372           JAXUCZ010000006.1  136936784-136937044
            3373-3528           JAXUCZ010000006.1  136938967-136939122
            3529-3599           JAXUCZ010000006.1  136939528-136939598
            3600-3709           JAXUCZ010000006.1  136940854-136940963
            3710-3806           JAXUCZ010000006.1  136941904-136942000
            3807-3945           JAXUCZ010000006.1  136947242-136947380
            3946-4064           JAXUCZ010000006.1  136952257-136952375
            4065-4137           JAXUCZ010000006.1  136964289-136964361
            4138-4861           JAXUCZ010000006.1  136965502-136966225
FEATURES             Location/Qualifiers
     source          1..4861
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q32"
     gene            1..4861
                     /gene="Tdrd9"
                     /note="tudor domain containing 9"
                     /db_xref="GeneID:299343"
                     /db_xref="RGD:1306942"
     exon            1..305
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     CDS             85..4239
                     /gene="Tdrd9"
                     /EC_number="3.6.4.13"
                     /note="putative ATP-dependent RNA helicase TDRD9; tudor
                     domain-containing protein 9"
                     /codon_start=1
                     /product="ATP-dependent RNA helicase TDRD9"
                     /protein_id="NP_001406506.1"
                     /db_xref="GeneID:299343"
                     /db_xref="RGD:1306942"
                     /translation="MLRKLTVDQINDWFTIGKTVTNVELLGLPPAFPAEAPREEVQRS
                     EEVPSEAPTAQAQDPVKATALARPASAFGRSLSQRSSEVEYINKYRQLEAQELDIYGQ
                     DQPPSGPGLRSPLAKISNVACIPETTYKYPDLPINRCKEEVISLIESNSVVIIHGATG
                     SGKSTQLPQYVLDHYTQRSAFCNIVVTQPRKIGASSIARWISKERSWTLGGLVGYQVG
                     LEKTATEDTRLIYMTTGVLLQKIVSAKSLMEFTHVFIDEVHERTEEMDFLLLVVRKLL
                     RTNSRFVKVILMSATINCKQFADYFAVPVQNKMNPAYVFEVEGKPHTIEQYYLNDLGH
                     IYHSGLPPYRLEEPVITKDVYEVAVSLIQMFDDLDMKESGNKTWSGAQFVSERSSVLV
                     FLPGLGEINYMHELLTNMIHKRLQVYPLHSSVTLEEQNNVFLSPVPGYRKIILSTNIA
                     ESSVTVPDVKYVIDFCLTRTLVCDEDTNYQSLRLSWASKTSCDQRKGRAGRVSKGYCY
                     RLIHRDFWDSAIPDHVVPEMLRCPLGSTVLKVKLLDMGEPRALLATALSPPSLSDIER
                     TILLLKEVGALAVSGQREDENPHDGELTFLGRVLAQLPVSQQLGKLIVLGHVFGCLDE
                     CLIIAAALSLKNFFTMPFRQHLDGYRNKVHFSGSSRSDCLALVEAFRAWQACRQRGEL
                     RHPKDELDWGRLNYIQIKRIREVAELYEELKNRISQFNMFVDPRHPVLDQEYPYKQRF
                     ILQVVLAGAFYPNYFTFGQPDEEMAVRELAGRDPKTTVVLKHIPPYGFLYYKQLQSLF
                     RQCGQVKSIVFDGAKAFVEFSRNPTERFKTLPAVNLAVKMSQLKVSLELSIHAAEEIE
                     GKVQGGSVSKLRNTRVNVDFQKQTVDPMQVSFNTLDRPRTVADLLLTVDVTEVVEVGH
                     FWGYRIDERNAELLRQLTAEINRLELVPLPIHPHPDLVCLAPFTDYNKESYFRAQILY
                     VSGNSAEVFFVDYGNRSHVDLDLLREIPCQLLELPFQALEFKICKMRPSAKSLICGEH
                     WSGGANGRFAALVSGCPLLVKVFSIVHSVLHVDVYRYSGAQDAVNIRDVLIREGYAEL
                     AEESYESKQSYEVLKGFFAKSVDTMPDGSVSSPMKDDEKHLIQILLESFASNRLGAPN
                     CKAVLHGPFNPYELKCHSLTRISKFRCVWIEKESINSVVISDSPADLHQRMLVAASLS
                     VNETGSTMLLRETSLMPHIPGLPALLSMLFAPVMELRVDREGKCYTGVLCGLGWNSTT
                     EAPILPEHDIELAFDVCFNVEDIVEINILRAAINKLACDGPHGPKYLGPERIAQLQEN
                     ARQKLLGLFCRLKPREKITPQWHEKPYEWNQVDPRLVIEQAEREGGPGKSTCLYQLHT
                     PVVLSP"
     exon            306..412
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            413..510
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            511..732
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            733..855
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            856..936
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            937..1101
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            1102..1205
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            1206..1270
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            1271..1325
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            1326..1410
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            1411..1468
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            1469..1573
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            1574..1671
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            1672..1803
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            1804..1969
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            1970..2033
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            2034..2097
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            2098..2142
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            2143..2196
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            2197..2313
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            2314..2421
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            2422..2522
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            2523..2696
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            2697..2808
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            2809..3021
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            3022..3111
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            3112..3372
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            3373..3528
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            3529..3599
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            3600..3709
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            3710..3806
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            3807..3945
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            3946..4064
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            4065..4137
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
     exon            4138..4861
                     /gene="Tdrd9"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttgtgggag gccgggaggg ccgtgcccta aaggctttgc caccattgga gtcaggcagt
       61 tgaggcagct cttgggcacc gaggatgttg cgcaagctca cggtcgacca gataaatgac
      121 tggttcacca taggcaagac ggtgaccaat gtggagctgc tgggcttgcc gcctgccttc
      181 cctgcggagg cgccccggga ggaggtccag cgctcggagg aggtccccag cgaggcccct
      241 acggcccagg cccaggatcc agttaaggcc acagcactgg ccagaccagc ttcagccttt
      301 ggaaggtcgc tcagccagag gagctcagaa gtagagtata ttaacaaata cagacagctt
      361 gaagcacaag aacttgatat ttatggccaa gatcagccac ccagtgggcc aggtctgagg
      421 tcaccattgg ctaagataag taatgtggca tgcatcccag agacaactta caaatatcct
      481 gatttgccta taaatcggtg taaagaagag gttatttcct tgatagaaag caattctgtg
      541 gtgatcatac acggtgccac agggagcggc aagagcacac agcttccaca gtacgtcctg
      601 gaccactaca cacagcgctc tgccttctgc aacatcgtag tcacccagcc acggaaaata
      661 ggggccagca gcattgccag gtggatcagt aaggagcgct cctggactct gggtggcttg
      721 gtaggctatc aggtagggct ggagaaaaca gcaacagaag acactcggct gatttacatg
      781 accactggag tcctgcttca gaagatcgtt agtgccaaga gcttgatgga gttcacgcac
      841 gtcttcattg atgaggtgca cgaacgaact gaagagatgg atttcctgct cttggtagtc
      901 cgtaaactcc tgaggacaaa ctcacgtttt gtgaaggtga tcctcatgtc tgccaccatc
      961 aactgcaagc agtttgcaga ctactttgct gttcctgttc agaacaagat gaaccctgca
     1021 tatgtgtttg aggtggaagg caagccccac actatcgaac agtattacct taatgatttg
     1081 gggcacattt atcacagtgg gctccccccc taccgtctgg aggagccagt gataacgaag
     1141 gacgtctatg aagttgccgt ctccctcatc cagatgttcg atgacctgga catgaaggag
     1201 agtgggaaca agacctggtc cggggcccag tttgtgtcgg agcggagcag cgtgctggtg
     1261 tttctgccag gtctgggtga gatcaattat atgcatgagc ttctcacaaa catgattcac
     1321 aaaaggttac aggtctatcc actccattcc agtgtgactt tagaagaaca gaataatgta
     1381 tttttaagtc cagtccctgg gtacagaaag attatcctgt caaccaacat tgcagagagt
     1441 tctgtcacag ttcctgatgt caaatatgtt atagattttt gcctgacccg aactctggtt
     1501 tgtgatgaag atacaaatta tcagagtctg cggctaagct gggcctcgaa gaccagctgt
     1561 gaccagagaa aaggccgtgc tggacgagtg tctaaaggat attgctacag gctgatccac
     1621 agggacttct gggacagcgc catccctgac cacgttgttc ctgagatgtt gcgctgtccg
     1681 ctgggaagca ccgtattgaa ggtgaagttg ctcgacatgg gtgaacctag agctctgctg
     1741 gcaaccgcgc tgtctccacc cagcctgagt gacatcgagc gcaccattct tctgttgaag
     1801 gaggttggag cactggcagt tagtgggcag agagaggacg aaaaccctca tgatggtgaa
     1861 ttgaccttcc tgggaagagt gctggcacag ctccctgtca gtcagcagct gggtaaactc
     1921 attgtgctgg gacatgtatt tgggtgcctg gatgagtgtc tcatcatagc ggcagctctt
     1981 tctctgaaga actttttcac gatgcctttt cgacagcatc tggatggata taggaacaaa
     2041 gtgcacttct caggaagtag caggagtgac tgcctggcac ttgtggaggc gttcagggcc
     2101 tggcaggctt gcagacagcg aggagagctg cggcatccca aggatgaact tgactgggga
     2161 cggctgaatt acattcaaat aaagagaatc agagaggtgg ctgagttata tgaagaattg
     2221 aagaatagaa tctcacagtt caacatgttt gtggatcctc gccatcctgt cttggatcag
     2281 gagtatccat ataagcagcg cttcatcctg caggttgtac tagctggtgc tttttatccg
     2341 aattacttta cttttggaca gccagacgag gagatggcag taagggagct ggcaggcaga
     2401 gacccaaaga caacagtcgt gctgaagcac atccccccct atggatttct ttactacaag
     2461 caactgcagt ctctcttcag acagtgcggt caagtcaaat ccattgtgtt tgatggcgca
     2521 aaagcctttg tggagttttc acggaatccg acagaaagat ttaagaccct ccctgctgtg
     2581 aacttggcag tcaagatgtc ccagttaaaa gtgtcccttg agctcagtat ccatgccgca
     2641 gaggagatcg aggggaaggt gcaaggcggg tcggtgtcaa agctcaggaa cacaagggtg
     2701 aatgtggact tccagaagca gacagtagac cccatgcaag tgtcattcaa caccctggac
     2761 agaccccgga cagtagcaga tctcctcctg acagttgatg tcactgaggt ggtagaagtg
     2821 gggcacttct gggggtacag gatcgacgag aggaacgcag agctgctgag acaactgact
     2881 gctgagataa accgcctaga gctggttcct ctgcctatcc acccgcatcc ggacttagtc
     2941 tgcctggcac ctttcactga ttacaacaag gagagctact ttagagctca aattctttat
     3001 gtttcgggaa attctgctga ggtattcttt gtagactatg ggaataggtc tcatgtagac
     3061 ctagatctcc tgagggagat cccctgtcag cttttggagc ttccatttca ggctttggaa
     3121 ttcaagattt gcaaaatgcg accatcagca aagtctctca tctgtggaga gcactggagt
     3181 ggaggcgcca atgggcggtt tgccgccctg gtcagcggct gccctctcct ggtgaaggtg
     3241 ttctccattg tacacagcgt cctgcacgtg gacgtgtacc gatactcggg cgcccaggat
     3301 gccgtcaaca tcagagacgt tctcatcagg gagggctatg ctgagcttgc agaggagtcc
     3361 tatgagtcca aacaaagcta tgaagtcctc aagggtttct ttgctaagtc agtggacacc
     3421 atgccggatg gctctgtgtc ctctcctatg aaggacgacg agaagcatct catccagatt
     3481 ctgttggaga gctttgcttc caatcggctg ggtgctccaa actgcaaggc tgtcctccac
     3541 gggcctttta atccttatga gctgaagtgt catagtctga ccagaatatc caagttcaga
     3601 tgtgtgtgga ttgagaagga gagcatcaat tctgtggtca tcagcgacag ccctgccgac
     3661 ctgcaccaga ggatgctggt tgcagcttca ctctcagtta acgagactgg gtccaccatg
     3721 ctcctgagag agacttccct gatgcctcac atcccaggcc tccccgcact cctcagcatg
     3781 ctgttcgcac cggtgatgga gttaagagtt gaccgtgaag gaaagtgtta cactggggtg
     3841 ctttgtggtt tggggtggaa ttcaactacg gaggccccta tactgccaga gcatgacatt
     3901 gagctggcct ttgatgtgtg cttcaacgtg gaggacatcg ttgagattaa tattctcagg
     3961 gctgctatca acaagctagc gtgtgatggg ccacatggac ccaagtatct tgggcctgag
     4021 agaattgctc agttgcagga gaatgcacgt cagaaacttc taggcttgtt ctgtcggttg
     4081 aaaccacgag agaagattac tcctcagtgg catgagaaac cctacgagtg gaaccaggtg
     4141 gacccaaggc tggtcatcga gcaggctgag cgggagggcg gcccagggaa gagcacttgc
     4201 ctgtaccagc tgcacacgcc tgtggtgctc agcccctgag acgctggtcc ccagctgccc
     4261 tccctgtggg cagtggcaga ggtctcctgc agctgcttcc tacccctgct accctcaggg
     4321 gcttctcctt cttgctgcct ttgctcagag tggagagtgg tgcttctgtt tgggtgggaa
     4381 aaatcagaaa gtctaatctt ctccagaaat gggggtcgtg gtattaaata ctttgcaaaa
     4441 agttgttctg aaagaagatt ttgtattctt ctttaaatat atgagggtaa atctaagtag
     4501 tcagtcccag aagaaaaggt tccagaatgt gtttgtatgc ctctcctgtc acagtttagc
     4561 tgttgtgcag gagagagcca gacacatgtg aaccccaccc ccagtgtgtg tgtgcgtgca
     4621 catgtcggtg caggcgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg cgcgcgcgcg
     4681 cgcattttct gatgttcctt tttcttcatt gaaaagatgt ggttttggta aaacttgagc
     4741 tttctgtgtt tgggacttgt ggttaaatta aacctcttgg cctgtgtttt ggaaattagg
     4801 agatgtgacc cgacaactgg catatctgca agacaataaa ggcattgacg ttgtgttctg
     4861 a
//
