LOCUS       NM_138871               3871 bp    mRNA    linear   ROD 13-NOV-2024
DEFINITION  Rattus norvegicus tudor domain containing 7 (Tdrd7), transcript
            variant 1, mRNA.
ACCESSION   NM_138871
VERSION     NM_138871.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3871)
  AUTHORS   Lachke,S.A., Alkuraya,F.S., Kneeland,S.C., Ohn,T., Aboukhalil,A.,
            Howell,G.R., Saadi,I., Cavallesco,R., Yue,Y., Tsai,A.C., Nair,K.S.,
            Cosma,M.I., Smith,R.S., Hodges,E., Alfadhli,S.M., Al-Hajeri,A.,
            Shamseldin,H.E., Behbehani,A., Hannon,G.J., Bulyk,M.L., Drack,A.V.,
            Anderson,P.J., John,S.W. and Maas,R.L.
  TITLE     Mutations in the RNA granule component TDRD7 cause cataract and
            glaucoma
  JOURNAL   Science 331 (6024), 1571-1576 (2011)
   PUBMED   21436445
REFERENCE   2  (bases 1 to 3871)
  AUTHORS   Hosokawa,M., Shoji,M., Kitamura,K., Tanaka,T., Noce,T., Chuma,S.
            and Nakatsuji,N.
  TITLE     Tudor-related proteins TDRD1/MTR-1, TDRD6 and TDRD7/TRAP: domain
            composition, intracellular localization, and function in male germ
            cells in mice
  JOURNAL   Dev Biol 301 (1), 38-52 (2007)
   PUBMED   17141210
REFERENCE   3  (bases 1 to 3871)
  AUTHORS   Hirose,T., Kawabuchi,M., Tamaru,T., Okumura,N., Nagai,K. and
            Okada,M.
  TITLE     Identification of tudor repeat associator with PCTAIRE 2 (Trap). A
            novel protein that interacts with the N-terminal domain of PCTAIRE
            2 in rat brain
  JOURNAL   Eur J Biochem 267 (7), 2113-2121 (2000)
   PUBMED   10727952
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Nov 27, 2020 this sequence version replaced NM_138871.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB030644.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760386, SAMEA5760393
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-277               JAXUCZ010000005.1  65041316-65041592
            278-490             JAXUCZ010000005.1  65061798-65062010
            491-632             JAXUCZ010000005.1  65063144-65063285
            633-813             JAXUCZ010000005.1  65064117-65064297
            814-894             JAXUCZ010000005.1  65064864-65064944
            895-968             JAXUCZ010000005.1  65066269-65066342
            969-1186            JAXUCZ010000005.1  65068418-65068635
            1187-1770           JAXUCZ010000005.1  65080305-65080888
            1771-1957           JAXUCZ010000005.1  65083244-65083430
            1958-2069           JAXUCZ010000005.1  65085999-65086110
            2070-2272           JAXUCZ010000005.1  65088846-65089048
            2273-2407           JAXUCZ010000005.1  65090039-65090173
            2408-2494           JAXUCZ010000005.1  65091628-65091714
            2495-2629           JAXUCZ010000005.1  65093832-65093966
            2630-2740           JAXUCZ010000005.1  65096417-65096527
            2741-3243           JAXUCZ010000005.1  65098279-65098781
            3244-3404           JAXUCZ010000005.1  65101791-65101951
            3405-3871           JAXUCZ010000005.1  65107699-65108165
FEATURES             Location/Qualifiers
     source          1..3871
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q22"
     gene            1..3871
                     /gene="Tdrd7"
                     /gene_synonym="Pctaire2bp"
                     /note="tudor domain containing 7"
                     /db_xref="GeneID:85425"
                     /db_xref="RGD:619724"
     exon            1..277
                     /gene="Tdrd7"
                     /gene_synonym="Pctaire2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            278..490
                     /gene="Tdrd7"
                     /gene_synonym="Pctaire2bp"
                     /inference="alignment:Splign:2.1.0"
     CDS             284..3625
                     /gene="Tdrd7"
                     /gene_synonym="Pctaire2bp"
                     /note="isoform 1 is encoded by transcript variant 1; tudor
                     domain-containing protein 7; trap; PCTAIRE2-binding
                     protein; tudor repeat associator with PCTAIRE-2"
                     /codon_start=1
                     /product="tudor domain-containing protein 7 isoform 1"
                     /protein_id="NP_620226.1"
                     /db_xref="GeneID:85425"
                     /db_xref="RGD:619724"
                     /translation="MLEADLVSKMLRAVLQSHKNGIVLPRLQGEYRSLTGDWIPFKQL
                     GYPTLEAYLRSVPAVVRIEASRSGEIVCYAVACTETARIAQLVARQRTSKRKTGRQIN
                     CQMRVKKTMPFFLEGKPKATLRQPGFASDYSISKKPNPTLLREKGSTLGAKADVDMPP
                     YPDAPVQRHVSMSANSSVTVLRSHPEASKLQFMGYSPKPHCLLLFSPKSSLPAPFQTH
                     ISRACPKEVNDNLNQTVEKPNVTPPASYTNKMDEVQNRIKEILDKHNNGIWISKLPHF
                     YKEFYKEDLNQGVLQQFEHWPHICTVEKPCGGGQDLLLYPAKREQPLRSDQDPEKERP
                     PPPPAPRQEVPSKGSPAVMPDVKEKVAELLGKYSSGLWASALPKAFEDMYKVKFPEDA
                     LKNLASLSDVCTINYISGNTQKAILYAKLPLPTDKILKDEAQAQGDFDIKSMIEQEYL
                     QIEKNMAESADDFVEDITVPPLVIPTEASPSVLVVELSNTNDVVIRYVGKDYSAAQEL
                     MEDEMKEYYSRNPRVTPIQTVHVGQLLAVNAEEDAWLRAQIISTDENKIKVCYVDYGF
                     CENIEKSKAYRLNPRFCSLSFQATKCKLAGLEILNDDPNLVKVVESLTCGKIFAVEIL
                     DKSDIPLVVLYDTSGEDDININATCLKAICDRSLEVHLQVDAMYTNVKVTNICSDGTL
                     YCQVPCKGLNKLNDLLHKTEDYFHCKHMTSEYFISLPFCGKICLFHCKGKWLRVEITN
                     VHSSRALDVQFLDSGNSTSVKVSELREIPPRFLQEMLAIPPQAIKCCLADLPQSIGMW
                     TPDAVLWLRDSVLNCSDCSIKVTKVDEARGVAYVYLFTPKNFPDPHRSINRQITNADL
                     WKHQKDVFLSAVSAAASSPGNRNASTPAPGSPAESLRKSHPEVLRKSVLDHTSSFSLE
                     ELPPPVHLSKSGEHMDVYVPVACHPGHFVIQPWQEIHKLEVLMEEMILYYSVSEERHI
                     AVERDQVYAAKVENKWYRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDVFRKL
                     PFQAVTAQLAGVKCSQWSEEASMVFRNHVEKKPLVALVQTVIEHANPWDRKVVVYLVD
                     TSLPDTDTWIHDFMSQYLVELSKAN"
     exon            491..632
                     /gene="Tdrd7"
                     /gene_synonym="Pctaire2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            633..813
                     /gene="Tdrd7"
                     /gene_synonym="Pctaire2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            814..894
                     /gene="Tdrd7"
                     /gene_synonym="Pctaire2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            895..968
                     /gene="Tdrd7"
                     /gene_synonym="Pctaire2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            969..1186
                     /gene="Tdrd7"
                     /gene_synonym="Pctaire2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            1187..1770
                     /gene="Tdrd7"
                     /gene_synonym="Pctaire2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            1771..1957
                     /gene="Tdrd7"
                     /gene_synonym="Pctaire2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            1958..2069
                     /gene="Tdrd7"
                     /gene_synonym="Pctaire2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            2070..2272
                     /gene="Tdrd7"
                     /gene_synonym="Pctaire2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            2273..2407
                     /gene="Tdrd7"
                     /gene_synonym="Pctaire2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            2408..2494
                     /gene="Tdrd7"
                     /gene_synonym="Pctaire2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            2495..2629
                     /gene="Tdrd7"
                     /gene_synonym="Pctaire2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            2630..2740
                     /gene="Tdrd7"
                     /gene_synonym="Pctaire2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            2741..3243
                     /gene="Tdrd7"
                     /gene_synonym="Pctaire2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            3244..3404
                     /gene="Tdrd7"
                     /gene_synonym="Pctaire2bp"
                     /inference="alignment:Splign:2.1.0"
     exon            3405..3871
                     /gene="Tdrd7"
                     /gene_synonym="Pctaire2bp"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggcgtcggt ttcccctctt acacgcggaa ctcgaagtgg gcggccgtgg ccgcagtgct
       61 tgcgtctgcg cagagctgag ccggccggct aaggggcggg gcgtggtgcg acagggcgtg
      121 gcctagaagg cggggcttta ggtgattccc aagccgcggc tcaggccgtg ctggggaaac
      181 cgaaagtggg cggcggccgc gtccggggcc ctggcggagg tggcggaggg agccgggccc
      241 agaggcgcgg gcgtgggccg cgggcccccg ggacgaggca aagatgctgg aggcagatct
      301 ggtctccaag atgctacggg ctgtcctgca gtctcataag aacgggatag tactgccccg
      361 gctccaagga gagtaccgct ctttgactgg agactggatc cccttcaaac agctgggcta
      421 cccaactctg gaagcgtatc tgaggagcgt gccagcggtt gtcaggatag aggctagtag
      481 atctggagag attgtctgct atgctgtagc ctgcacagag actgcgagga ttgctcagct
      541 tgtggctcgt cagaggacct ctaaaaggaa aacagggcga caaattaatt gtcagatgag
      601 agtgaagaaa accatgccat tctttctaga agggaaaccc aaggcaaccc tcagacaacc
      661 aggatttgct tcagactatt ctatcagcaa gaaacccaat ccaacgctgt taagagaaaa
      721 aggaagcacc ttgggagcta aggctgatgt ggacatgcca ccttacccag acgctccagt
      781 gcagaggcac gtgagcatgt ctgccaacag cagtgttacg gttttaagaa gtcacccaga
      841 ggccagcaag ctacaattta tgggctacag tccaaaacct cactgtctgc ttttgttcag
      901 tccaaagtca tccctgccag cacctttcca gacacacatc tcacgggcct gccctaagga
      961 agtgaatgat aatttaaatc agactgttga gaaaccaaat gtcacgcctc ctgcctctta
     1021 cactaataag atggatgagg ttcaaaaccg cataaaggaa atattagaca agcataacaa
     1081 tggcatttgg atctctaagc ttccacattt ttacaaagag ttttataaag aagaccttaa
     1141 ccaaggagtt ttacagcagt ttgaacactg gcctcacatt tgcacggtgg aaaaaccttg
     1201 tggtggtggt caagatttac ttctttatcc tgccaagaga gagcagccct tgagaagtga
     1261 ccaggacccc gagaaggagc gcccacctcc accacctgct cccaggcagg aggtgccatc
     1321 aaaggggagc ccagcagtga tgccggatgt caaagagaaa gtggccgagc tgctggggaa
     1381 atactcaagc ggcctttggg caagtgcact ccctaaagca tttgaggaca tgtacaaagt
     1441 caagttccct gaggatgcct taaaaaatct tgcctcactc tctgatgtgt gcaccataaa
     1501 ctacatttct ggaaataccc agaaggcaat tctctatgca aaactcccat tgcccacaga
     1561 caagatctta aaggatgaag cgcaggcaca aggagatttt gacatcaagt caatgattga
     1621 acaagagtat ttgcagatag aaaaaaacat ggctgagagt gctgatgact ttgtggagga
     1681 cataactgtg ccgcctctgg taattcctac cgaggcttca ccgtctgtgt tggtggtgga
     1741 gctgagcaac acaaatgatg tggttatcag gtatgtaggc aaagactact cggctgccca
     1801 ggagctcatg gaagacgaga tgaaggagta ttacagtagg aaccccagag tcacaccaat
     1861 ccagaccgtg cacgtggggc agctgctggc agtcaatgca gaggaggatg cctggttacg
     1921 agcacagatc atctccacgg acgagaacaa gataaaggtg tgctatgttg actatggctt
     1981 ttgtgaaaac attgagaaga gtaaagcata ccgactgaac ccacggttct gctctctgtc
     2041 ctttcaagct acaaagtgca aactagcagg gctggagatt ctgaatgatg atcccaacct
     2101 cgtgaaggtg gtggagtcat taacgtgcgg gaagatcttt gctgtggaga tactggacaa
     2161 gtcagatatc ccactggttg tgctgtatga cacttcagga gaggatgaca tcaacatcaa
     2221 tgccacctgc ctgaaggcca tatgtgacag atctctagaa gttcatctcc aggtggacgc
     2281 catgtacaca aatgtcaaag tgactaacat ttgctctgat ggaacactct actgccaggt
     2341 gccatgcaag ggtctgaaca aactcaatga ccttctgcat aagacggagg actacttcca
     2401 ctgcaagcac atgacctctg agtacttcat ctcgctaccc ttctgtggga agatctgcct
     2461 cttccattgc aaagggaaat ggttacgagt ggagatcaca aatgttcaca gcagccgagc
     2521 cctcgacgtt cagttcctgg actctggcaa ttcgacatcc gtgaaagtgt cggaactcag
     2581 agaaattcca ccacggttcc tgcaggaaat gcttgccatc ccccctcagg ctatcaagtg
     2641 ctgtttggct gatcttccac agtccattgg catgtggaca ccagacgctg ttctttggct
     2701 aagagattct gttttgaatt gctcggactg tagtattaag gttacgaaag tggatgaggc
     2761 caggggcgtg gcctacgtgt atttattcac ccccaagaac ttcccggatc cccaccgcag
     2821 catcaaccgg cagatcacaa acgcagacct gtggaagcac cagaaggatg tgtttctgag
     2881 cgctgtgtct gctgcagcca gctctcccgg caacaggaat gccagcacac ctgctccagg
     2941 cagccctgcg gagagcctca gaaagagcca cccggaggtc ctcagaaagt ctgttctgga
     3001 ccacaccagc tctttctcct tggaggaact gccccctcct gtccacctgt caaagtcagg
     3061 ggaacacatg gatgtgtatg tgcctgtggc ctgtcaccca ggccatttcg tcatccagcc
     3121 ttggcaggag atccacaagc tggaggtgct gatggaagag atgatcctgt actacagcgt
     3181 gtctgaggag cgccacatag cggtggagag agaccaagtg tatgcagcca aagtggagaa
     3241 caagtggtac agggtgctgt taaaaggaat cctgacaaat gggctggtgt ctgtgtacga
     3301 gctggactat ggcaaacatg agctagtcaa cataaggaag gtgcagcccc tagtggacgt
     3361 gttccggaag ctgccattcc aggcagtcac tgctcaactt gcaggagtga agtgcagcca
     3421 atggtcggaa gaggcttcaa tggtgtttcg aaatcacgtg gagaagaaac ccctggtggc
     3481 actggtgcag acagttattg aacacgctaa cccttgggac cggaaagtag tggtctatct
     3541 agtagacaca tcgctgccag acactgacac ctggattcat gactttatgt cacagtatct
     3601 ggtagagctt tcaaaagcta attaatcact gcttgagacc ttgaccgtta atgcagattg
     3661 ttctctaagc aataatacaa aatgtgtagt agggtcttaa aacatcttat ttttactaca
     3721 tggctctgac tgttgtggag gattgaaaag aatatgcttt gtttgatgaa agatatttaa
     3781 caagttttgt ttaacgcagt tgacttttca aagaaaaatt gcacttgaat tattaatata
     3841 atattagaat aaaatgttta gcaatgtaaa a
//
