LOCUS       NM_001191583            6908 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus tudor domain containing 6 (Tdrd6), mRNA.
ACCESSION   NM_001191583 XM_002730003
VERSION     NM_001191583.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6908)
  AUTHORS   Akpinar,M., Lesche,M., Fanourgakis,G., Fu,J., Anastassiadis,K.,
            Dahl,A. and Jessberger,R.
  TITLE     TDRD6 mediates early steps of spliceosome maturation in primary
            spermatocytes
  JOURNAL   PLoS Genet 13 (3), e1006660 (2017)
   PUBMED   28263986
  REMARK    Erratum:[PLoS Genet. 2017 Sep 1;13(9):e1006989. doi:
            10.1371/journal.pgen.1006989. PMID: 28863135]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6908)
  AUTHORS   Vasileva,A., Tiedau,D., Firooznia,A., Muller-Reichert,T. and
            Jessberger,R.
  TITLE     Tdrd6 is required for spermiogenesis, chromatoid body architecture,
            and regulation of miRNA expression
  JOURNAL   Curr Biol 19 (8), 630-639 (2009)
   PUBMED   19345099
REFERENCE   3  (bases 1 to 6908)
  AUTHORS   Choi,E., Lee,J., Oh,J., Park,I., Han,C., Yi,C., Kim,D.H., Cho,B.N.,
            Eddy,E.M. and Cho,C.
  TITLE     Integrative characterization of germ cell-specific genes from mouse
            spermatocyte UniGene library
  JOURNAL   BMC Genomics 8, 256 (2007)
   PUBMED   17662146
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6908)
  AUTHORS   Hosokawa,M., Shoji,M., Kitamura,K., Tanaka,T., Noce,T., Chuma,S.
            and Nakatsuji,N.
  TITLE     Tudor-related proteins TDRD1/MTR-1, TDRD6 and TDRD7/TRAP: domain
            composition, intracellular localization, and function in male germ
            cells in mice
  JOURNAL   Dev Biol 301 (1), 38-52 (2007)
   PUBMED   17141210
REFERENCE   5  (bases 1 to 6908)
  AUTHORS   Pan,J., Goodheart,M., Chuma,S., Nakatsuji,N., Page,D.C. and
            Wang,P.J.
  TITLE     RNF17, a component of the mammalian germ cell nuage, is essential
            for spermiogenesis
  JOURNAL   Development 132 (18), 4029-4039 (2005)
   PUBMED   16093322
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Jul 17, 2010 this sequence version replaced XM_002730003.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-6061              JAXUCZ010000009.1  24841454-24847514
            6062-6189           JAXUCZ010000009.1  24849502-24849629
            6190-6279           JAXUCZ010000009.1  24851259-24851348
            6280-6343           JAXUCZ010000009.1  24854685-24854748
            6344-6908           JAXUCZ010000009.1  24856057-24856621
FEATURES             Location/Qualifiers
     source          1..6908
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q13"
     gene            1..6908
                     /gene="Tdrd6"
                     /note="tudor domain containing 6"
                     /db_xref="GeneID:316254"
                     /db_xref="RGD:1305956"
     CDS             1..6411
                     /gene="Tdrd6"
                     /codon_start=1
                     /product="tudor domain-containing protein 6"
                     /protein_id="NP_001178512.1"
                     /db_xref="GeneID:316254"
                     /db_xref="RGD:1305956"
                     /translation="MSSTPGLPTPGASLALRVSFVDVHPEVIPVQLWGLVGQRREEYV
                     RLSREIQEAAATRGPWALGGASASPGELCLVQVGLMWHRCRVVSRQAQDSRVFLLDEG
                     RTITAGAGSLAPGRSEFFHLPSEVLGCVLAGLVPAGGGGAGGGEPQHWSPNAVDFLSN
                     LQGKEVHGRVLDVLLLHRLVLLEVPVVSQQMEELGLARHVPDSLFCSLLKRYLTAAGL
                     GSSGAPVLPRAAPKQEHPGLDYFYPQLQLGVTEPVVVTQVCHPHRIHCQLRSLSQEIH
                     RLSESMAQVYRAPTGTEDEDSGSATWEEREESPDKPGSPCASCGLDGQWYRALLLETF
                     RPQRCAQVLHVDYGRKELVSCSSLRYLLPEYFRMPVVTYPCALYGLWDCGRGWSRSQV
                     GDLKALILGQAVNAKIEFYCSFEHMYYVTLYGEDGINLNSAFGVQSCCLADRFLQSQG
                     IEEEEDEDEDEMEAAFQSQSPAEEMEEEVSLPSLRSIRLKMNTFYDAQVEFVKSPSEF
                     WIRLRKHKNTFSKLTKRMCSFYSSASKLDGVILKPEPDDLCCVKWKENGYYRAMVTRL
                     DSKSVDVFLVDRGNSENVDWCDVRMLLPQFRQLPILALKCTLADIWPLGKTWSQEAIS
                     FFKKTVLHKELVVHILDKQDRQYVIEILDESRTGEENISKVIAQAGYAKFQEFETKEN
                     IRLSAHSPGHVSGHFIAESSKIPSVKKVEGDQKAKNDNKTLSDPEALATVSLSNISTG
                     QTAQDKEKVTSDPTLLMLNLLKTKPDCCGKGELEVGSTVEVKVSHIENPGSFWCQLMR
                     NAQGFRTLMCDIEDYCKSEPSPYEGDTRACLAKRTANGRWSRALISGAQSLEHVRVVF
                     VDYGDKDVVSMKDILSVSDVFFKVRAQAFRCSLYNLIQPTGENPFVWDERAIQAFTGF
                     IDNAWQNNLELKCTIFALASRHEEECFNVVDLLTPFQSACHFLVEKRLARPVKLQKPL
                     EPSVQLHSYYYSTHDLKIGSEELVYITHADDPWTFYCQLARNTNILEQLSYHIMQLSK
                     VLLNLRTSTLVPGTLCLAKYTDGNWYRGIIIEKEPSKVFFVDFGNTYVASDHLLPIPR
                     DAYDVLLLPMQAVKCSLSDIPHHIPEEVTAWFQETVLDKSLKALVVAKDPDGRLIIEL
                     YDESVQINASINEKLGLLGYKNRTRRKDKENEIILRETETLQDKAEIMKPSPTDYLGK
                     SGDSKAHGVEIMGESCKPKLSPACKELKYLQGSGKAHLVTPYQDSMGNKNDGGFLLTR
                     EKREDMFASSPMSATKLESALPERRMGEASGKDLPPKFCEFPQKTIAPGFKTSVYVSH
                     INDLSDFYIQLIEDETEINRLSERLNDVRTRPQYHTGPPWQSGDVICAVFPEDNLWYR
                     AVVLEQQHNDLLSVQFIDYGNMSVVHTNRTGRLGPIDAVLPALCLHCSLRGIVVPDIV
                     GTKEMVAYFSQRTDEAQIRCEFVKFQGTWEVILADEHGIIAEDIINRFPFNGKSQAGL
                     TTQSMKGDCSKTALKTNMDTSVFLNWYNPKMKLIKAYATVIDGPEYFWCQFADSEKLQ
                     YVETEVQNAAKQLADRKSCTQCPQIGDPCIVRYREDGHYYRALITNICDDHLASVRLV
                     DFGNVEDCVDTNALWSIPSELLLVPMQAFPCCLSGFTVSGGVCPQEGNDYFYDIVTED
                     VLEITILEIKRDVCDIPLAVVELRSKGENINEKMKKYAKTGTPKSGLYSEKHGAERKG
                     GLSSPDLGLKKPSHKIAQEKTFYMEARASELSERFEKDLNIETRPSKFYERSPRNIFN
                     AFEHSCQGKMGSQRLEGGMDYHFVDRVKYDDTYLMTGFNPILAHASEPKELLELNSLE
                     VPLSPDDECKEFLELESIDLQHSPAGEEDKEELGLGSPMAPLSPGCQAGATLEPFMVQ
                     LPLDCEAEKQLELELPTPQLSLEDSISPLSATVSQNMPESRSAEDERKSSCVGSSDDD
                     DDHSASPLPHHGKGGDSPAHDEMNLSEEEFPQFENRDSAALLAPLFSEEEARGGRKGR
                     SEVPAVELQNTYTLKGFSVGSKCVVWSSLRNTWSKCEILALAEEGTRVLNLANGVEET
                     VSPENVWNGIPKVDKRPSEAAFQTVGKDLPFTPSDDTTIEGFFCSVSEEECGGDADSA
                     KLNV"
     exon            1..6061
                     /gene="Tdrd6"
                     /inference="alignment:Splign:2.1.0"
     exon            6062..6189
                     /gene="Tdrd6"
                     /inference="alignment:Splign:2.1.0"
     exon            6190..6279
                     /gene="Tdrd6"
                     /inference="alignment:Splign:2.1.0"
     exon            6280..6343
                     /gene="Tdrd6"
                     /inference="alignment:Splign:2.1.0"
     exon            6344..6908
                     /gene="Tdrd6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgagttcga ctccggggct gcccactccg ggggcctcgc tggccctgcg ggtgtccttc
       61 gtggacgtgc atcccgaggt gatcccggtg cagctgtggg gactggtggg tcagcggcgg
      121 gaggagtacg tgaggctgag ccgggagatc caggaggcgg cagccacgcg gggtccctgg
      181 gcgctgggtg gggcgtcggc atcgcccggg gagttgtgcc tggtgcaggt ggggctcatg
      241 tggcaccgct gccgcgtggt cagccgccag gcgcaagaca gccgcgtctt cctgctggat
      301 gagggccgca ccatcacggc gggcgcgggc tcgctggccc cagggcgcag cgagttcttc
      361 cacctgccct ccgaagtgtt gggctgtgtg ctagcgggcc tggtgcccgc gggtggcggt
      421 ggcgctggcg gtggcgaacc ccagcactgg tcccccaacg ctgtggactt ccttagcaac
      481 cttcagggta aggaggtgca cggacgggtc ctggacgtgc tgctcctcca tcgcctggtg
      541 ctgctggagg tgccggttgt gtctcagcag atggaggagc tgggtctggc ccggcacgtg
      601 cccgacagcc tcttctgttc gctgctcaaa cgctatctga cggcggccgg gttggggagc
      661 tccggagctc cagttctccc gcgagccgcg cccaaacaag agcatcctgg cttggattac
      721 ttttatcccc aactgcagct gggagtgacg gagccggtgg tggtaaccca agtatgccat
      781 ccccaccgaa ttcactgcca actccggagt ctctcgcagg agatccaccg tctctctgag
      841 agcatggctc aggtataccg ggcgcccacg gggacagagg atgaggactc tggcagtgcc
      901 acctgggagg agagggagga gagtcctgac aagccggggt ctccatgtgc ttcctgtggc
      961 ttggatggac agtggtatcg ggctctcttg cttgagacct tcaggcctca gcgctgtgcc
     1021 caggtgcttc acgtcgatta cggaaggaaa gaactagtaa gctgcagcag ccttcgctat
     1081 ctgctgccgg agtatttccg aatgcccgtg gtgacctacc cttgtgcact gtatggactg
     1141 tgggactgcg gaagaggctg gtcccggtca caagtaggcg atctgaaagc tctgatcctg
     1201 ggccaggcag tgaatgcaaa gattgaattt tactgttcct ttgagcacat gtattatgtc
     1261 accctgtatg gggaagatgg gattaatctg aacagtgcgt tcggagtgca atcctgttgc
     1321 ctggctgacc gctttcttca gagccagggg atagaggagg aagaggatga agatgaggat
     1381 gaaatggagg cagcgtttca gtctcagtcc cccgctgagg aaatggaaga ggaagtttcc
     1441 ctcccgtcct tgagatctat caggttgaag atgaatactt tctatgacgc ccaggtggag
     1501 ttcgtgaaga gcccttccga gttctggatt cgccttagaa agcacaagaa tacgttcagc
     1561 aagctgacga agagaatgtg cagtttttat tcttctgcca gtaagctgga tggggttatt
     1621 ttgaaaccgg aaccggatga cctttgctgt gtgaaatgga aagaaaatgg ctattaccgg
     1681 gccatggtca cccgattgga cagcaagagt gtagatgtgt tcctggtgga ccggggcaac
     1741 tctgagaacg ttgactggtg tgatgtgaga atgttgctgc ctcagtttag gcagctacca
     1801 atattggctc tgaagtgcac cctggctgac atctggcctc tggggaaaac ttggagccag
     1861 gaggcgattt cattttttaa aaagacggtg ctacacaaag aattggtggt ccacattctc
     1921 gataagcagg atcgccagta tgtcatagag attctggatg aatccaggac cggggaggaa
     1981 aacattagta aggtcatcgc tcaagctgga tatgccaagt tccaggaatt tgaaaccaaa
     2041 gaaaacatca gactcagtgc ccactccccc ggccatgttt cgggtcattt tattgcagag
     2101 tctagcaaaa taccttctgt caagaaggtc gaaggagacc agaaagccaa gaacgacaat
     2161 aaaaccctct ctgatccaga agctctggcc acggtaagcc tttctaacat ttccactgga
     2221 caaactgcac aggacaaaga gaaggtaaca tctgacccaa cgctcctcat gctgaattta
     2281 ctgaaaacaa aaccagactg ctgtggtaaa ggggaactgg aggtaggcag cactgttgaa
     2341 gtcaaagtgt ctcacattga aaaccctggc tccttctggt gtcagctgat gaggaacgcc
     2401 caaggcttca gaactctgat gtgcgacatt gaggactatt gcaaaagtga gccgtctccc
     2461 tatgaggggg acacgcgtgc ttgtctggca aagcgaacag ccaacgggag atggtccaga
     2521 gctctgatta gtggggcaca atctttagag catgttagag tggtgtttgt ggactatgga
     2581 gataaggatg tggtatctat gaaggacata ctctccgtca gtgatgtgtt cttcaaggtt
     2641 agagctcagg ccttccggtg cagtctttat aatttaattc aaccaactgg tgaaaacccg
     2701 tttgtctggg atgaaagggc aatacaggct tttactgggt tcatcgacaa cgcttggcag
     2761 aataacttag aattaaaatg cacaatcttt gctttggcat caaggcatga ggaagagtgc
     2821 ttcaatgttg tggacctgct aacaccgttt cagagcgcct gccatttttt ggtagaaaag
     2881 agacttgcta ggcccgtaaa gcttcagaag cccctggaac cttcagttca gctgcactcg
     2941 tactactatt ccacccatga cctaaaaatt ggaagtgaag aattggtgta cataacgcac
     3001 gccgatgacc cctggacatt ttattgccag cttgcaagaa acacaaacat tttagaacaa
     3061 ttatcctacc acatcatgca gttaagcaaa gtcttactga atttaaggac atccaccttg
     3121 gtccccggaa ccttgtgtct tgccaaatac acggatggaa actggtatag gggaataata
     3181 atagaaaaag aaccaagtaa ggtctttttt gttgattttg ggaacacgta cgtagcaagt
     3241 gaccacctgc tccccatccc ccgagatgcc tatgatgttt tacttctacc catgcaagct
     3301 gtgaaatgct ccttatccga catccctcat catatccccg aagaagtcac agcatggttc
     3361 caggagaccg ttttagataa gtcactgaag gctttagtcg tagccaagga cccagatggg
     3421 agactgatta tagagctcta cgacgagagt gtccaaatca atgccagtat taacgagaag
     3481 cttgggctcc ttggttacaa aaacagaaca agaagaaaag acaaagagaa tgaaataata
     3541 ctccgtgaga ccgagactct tcaagataaa gctgagatca tgaagccatc acctacagat
     3601 tatttgggta aatcgggaga cagcaaagca cacggtgtag agattatggg ggaatcgtgc
     3661 aaacccaagc tcagcccagc gtgtaaggaa ctcaaatatt tacaaggctc aggaaaggcc
     3721 cacctagtca caccatatca ggactctatg ggaaacaaaa atgacggagg gtttctatta
     3781 acgagggaga agagagaaga catgtttgcc agctcaccca tgagtgccac caaactagag
     3841 tctgctcttc ctgagagaag aatgggagaa gccagtggca aagatctgcc tcccaagttt
     3901 tgtgaattcc cacaaaagac aatagcgcct ggttttaaga cctctgtgta tgtttcgcat
     3961 attaacgacc tttcagattt ttacatccag ctgatagaag atgaaactga gatcaatcgc
     4021 ctttcggaga gactgaacga tgtcagaacg cggccccagt accacacagg tccaccatgg
     4081 caaagcggag acgtaatatg tgccgttttc ccagaggata acttgtggta ccgagcggta
     4141 gtcttggaac agcaacacaa cgaccttctc tctgtacagt ttatagatta tggcaacatg
     4201 tctgtggtcc acactaacag aaccggtcgg cttggcccca ttgatgcggt gttacctgcg
     4261 ctgtgcctcc actgctccct gagggggata gtggtacctg acatcgtagg cactaaggaa
     4321 atggtggcct acttttccca aaggacagac gaggctcaga tcagatgtga atttgttaaa
     4381 ttccaaggca cctgggaagt gattctcgcg gatgaacatg gaatcatagc tgaagatata
     4441 attaataggt ttccgttcaa tggaaaatct caagcggggc ttaccaccca atccatgaaa
     4501 ggggactgtt cgaagactgc tctcaaaacc aacatggata catcagtgtt tctcaactgg
     4561 tataacccca aaatgaaact gataaaagcc tacgccactg tgatagacgg gcccgagtac
     4621 ttttggtgcc agtttgccga ttctgagaag ttgcagtacg tagaaacgga ggtccaaaat
     4681 gctgccaagc agctggcaga caggaaaagc tgcacccagt gtccacaaat tggagatccg
     4741 tgtatcgtga ggtacagaga ggatgggcac tactatagag ccctcatcac taatatctgt
     4801 gacgatcacc tcgcatcggt cagacttgtg gactttggga atgtggaaga ttgtgtggac
     4861 accaacgcac tttggagcat cccttctgaa ctcctgctgg tccccatgca agcgtttcca
     4921 tgctgccttt ctggattcac tgtttctggc ggtgtgtgcc ctcaggaggg aaatgattat
     4981 ttctatgaca tagtcacaga ggatgtgtta gaaataacaa tattggagat taaaagagat
     5041 gtttgcgaca tccccttagc agttgtggag ctaaggagca aaggcgagaa cattaacgag
     5101 aagatgaaga agtatgctaa aacgggcaca cccaagagtg gcctgtactc cgagaagcac
     5161 ggcgcagaga gaaagggagg ccttagcagt cctgatcttg gcctcaagaa accaagccat
     5221 aaaatagcac aagagaagac attctacatg gaagcccggg caagtgagct ctcggagaga
     5281 ttcgaaaagg atttaaacat tgaaaccagg ccaagcaagt tctatgaacg cagcccccgt
     5341 aacatcttca atgcttttga gcactcgtgc cagggtaaaa tgggttctca gaggctggaa
     5401 ggtggcatgg attaccactt cgtggacaga gtcaagtatg acgataccta cctcatgacg
     5461 ggattcaatc cgatattggc ccatgctagt gaaccaaagg agctactgga actgaattct
     5521 ctcgaggtac cactctcccc cgatgacgaa tgcaaagagt tcttagaact ggagtccatt
     5581 gacttacaac actcccctgc tggggaggaa gacaaagagg agctaggcct ggggtctccg
     5641 atggcgcctc tgtccccagg ctgccaggcg ggagccaccc tggaaccatt tatggtgcag
     5701 cttcccctgg actgtgaggc cgagaagcag ctggagctgg aactccccac cccccagctg
     5761 tctctggagg acagcataag tcctctatcc gcaaccgtca gtcagaacat gccggaatcc
     5821 aggagtgcgg aggatgagag gaagtccagc tgcgtgggct cttctgatga cgatgacgac
     5881 cacagcgctt ccccactccc ccaccacggg aaggggggag attccccggc acacgacgaa
     5941 atgaacctgt ctgaagagga gtttccacaa tttgaaaaca gagacagcgc tgccttattg
     6001 gcacccttgt tctctgagga agaagccaga ggaggaagga agggcaggag cgaagtacca
     6061 gcagttgagc tacagaacac ctacactctg aaaggcttct ctgttggatc gaaatgtgtc
     6121 gtgtggtcga gcctaagaaa cacctggtct aagtgtgaga ttctggcact agcagaagaa
     6181 ggaacaaggg ttttgaacct tgcaaatggt gtggaggaga cagtaagccc tgagaatgtc
     6241 tggaatggta ttcccaaggt agataagaga ccctctgagg ctgcattcca aacagtagga
     6301 aaggaccttc ccttcacgcc atcggatgac accaccatcg aaggcttttt ttgttctgtt
     6361 tcagaggagg agtgcggagg tgacgcagat tcggccaagc tgaacgtata aactcggcca
     6421 atcagaagct gctttgaaca agtcacgtgc tacgcagacc aaacatgcta gaagaaatgt
     6481 aaagcatgtg acccctggaa cttgtccttt gggggacaaa ttgatttgtg gagaaactga
     6541 taggttgacg aaacagcctg tttgttgcta tttagaggaa tctggccttt tccctcagtc
     6601 tatatagcct cgtgtttctt ctcaggcagg ataatttatt ttgctaaaca atttgctaac
     6661 atattactat atccctaaag gggctacctt ttcaatagat tgtttatatt aaaatcgaaa
     6721 cttctaggtt ctcaatgagc atgataggat gccaccaagt gccacggctt tgttagacag
     6781 actgtccgag ccttgtttgt cttttgaagc ttcgcctcgt gtatctactg aaataggtgg
     6841 caacttctct gtttgaacct ggaatgcaac acgtgcaacc caagatttga ataaagttta
     6901 tccttaaa
//
