LOCUS       NM_001012043            2660 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus tudor domain containing 3 (Tdrd3), mRNA.
ACCESSION   NM_001012043 XM_224400
VERSION     NM_001012043.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2660)
  AUTHORS   Lu,R. and Wang,G.G.
  TITLE     Tudor: a versatile family of histone methylation 'readers'
  JOURNAL   Trends Biochem Sci 38 (11), 546-555 (2013)
   PUBMED   24035451
  REMARK    Review article
REFERENCE   2  (bases 1 to 2660)
  AUTHORS   Musselman,C.A., Lalonde,M.E., Cote,J. and Kutateladze,T.G.
  TITLE     Perceiving the epigenetic landscape through histone readers
  JOURNAL   Nat Struct Mol Biol 19 (12), 1218-1227 (2012)
   PUBMED   23211769
  REMARK    Review article
REFERENCE   3  (bases 1 to 2660)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (bases 1 to 2660)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (bases 1 to 2660)
  AUTHORS   Yang,Y., Lu,Y., Espejo,A., Wu,J., Xu,W., Liang,S. and Bedford,M.T.
  TITLE     TDRD3 is an effector molecule for arginine-methylated histone marks
  JOURNAL   Mol Cell 40 (6), 1016-1023 (2010)
   PUBMED   21172665
REFERENCE   6  (bases 1 to 2660)
  AUTHORS   Kashima,I., Jonas,S., Jayachandran,U., Buchwald,G., Conti,E.,
            Lupas,A.N. and Izaurralde,E.
  TITLE     SMG6 interacts with the exon junction complex via two conserved
            EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decay
  JOURNAL   Genes Dev 24 (21), 2440-2450 (2010)
   PUBMED   20930030
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC081929.1.
            
            [WARNING] On Jul 17, 2024 this sequence was replaced by
            NM_001012043.2.
            
            On Feb 11, 2005 this sequence version replaced XM_224400.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC081929.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132274, SAMD00132291
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2660
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15q12"
     gene            1..2660
                     /gene="Tdrd3"
                     /note="tudor domain containing 3"
                     /db_xref="GeneID:306066"
                     /db_xref="RGD:1310126"
     exon            1..191
                     /gene="Tdrd3"
                     /inference="alignment:Splign:2.1.0"
     exon            192..276
                     /gene="Tdrd3"
                     /inference="alignment:Splign:2.1.0"
     exon            277..338
                     /gene="Tdrd3"
                     /inference="alignment:Splign:2.1.0"
     exon            339..499
                     /gene="Tdrd3"
                     /inference="alignment:Splign:2.1.0"
     CDS             426..2381
                     /gene="Tdrd3"
                     /codon_start=1
                     /product="tudor domain-containing protein 3"
                     /protein_id="NP_001012043.1"
                     /db_xref="GeneID:306066"
                     /db_xref="RGD:1310126"
                     /translation="MLRVQMTDGHTSCTAVEFSYISKISLNTPPGTKVKLSGTVDIKN
                     GFLLLSDSNTTVLGGEVEHLIDKWALQRSLLKHNRSNIGAEGGPPPFLPFGQKCASTV
                     QVDSRELDRRKTLQVSLPAKPTNDNDEFEKQRTAAIAEVAKSKETKTFGGGGGGVRSH
                     LNIGAGGHRNREVSQKEKASKSESKNEGVYRELVDEKALKHITEMGFSKEASRQALMD
                     NANNLEAALNVLLNSSKQKPVVGPPPRGRGKGRGRVRSEDEEDLGNARPSAPSTLFDF
                     LESKMGTLNMEEPRSQPQHLYQGQHRVSNTEQNGIKDGNQSRHLPRNDPRQPRNEKPP
                     RFQRDTPNLKSALENSVLSRNRGSERPSSSSGSDVWAEERIKCDRPYSRYDRTKDASY
                     PLGFQHNDGAFKRRDNSMQNRSGRGPLYAEAKENPHPSEFVDYNNQKRGKRENQTSNP
                     DHFYDRKSRTMNSEAFSGLKIEKHFSANTDYQNPVQSNSFVGVPNGETDMPMKGRRVG
                     PIKPAGPVTAVPYDDKIFYNSGPKRRSGPIKPEKVIESSIPVEYAKMWKPGDECFALY
                     WEDNKFYRAEVEALHSSGMTAVVKFTDYGNYEEVLLSNIKPVQTEAWEEEGTYDHTIE
                     FRRGGDGQPRRSTRPTQQFYQPPRARN"
     exon            500..641
                     /gene="Tdrd3"
                     /inference="alignment:Splign:2.1.0"
     exon            642..713
                     /gene="Tdrd3"
                     /inference="alignment:Splign:2.1.0"
     exon            714..863
                     /gene="Tdrd3"
                     /inference="alignment:Splign:2.1.0"
     exon            864..1004
                     /gene="Tdrd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1005..1161
                     /gene="Tdrd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1287
                     /gene="Tdrd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1288..2138
                     /gene="Tdrd3"
                     /inference="alignment:Splign:2.1.0"
     exon            2139..2264
                     /gene="Tdrd3"
                     /inference="alignment:Splign:2.1.0"
     exon            2265..2389
                     /gene="Tdrd3"
                     /inference="alignment:Splign:2.1.0"
     exon            2390..2636
                     /gene="Tdrd3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cacagtcgaa cagaggagtt ttttttcttt ttcttttctt tcttcttttt tctctctttc
       61 ttctttttct tttttctggg tctccagcag gaggcctgtc ccccaccctc agttcagacc
      121 cccgccgtcc ccgagcctga gcagctaacc atggccgagg tgtccggcgc cgcgttgtcc
      181 caggcgggtt ggtatctttc agatgaaggc attgaagctt gtacaagctc tcctgggaaa
      241 gtcaatataa atgacatcat cctgattgct ctcaatattt gagaacaatt ggcaagaagt
      301 tcctccccag tgacatcagc ggtggaaagg tagaaaagct cgaaggtcca tgtgttttac
      361 aaattcagaa ggtccgcaat gtggctgcgc cgagggataa tgaggagtcc caagctgcgc
      421 caaggatgct gcgtgtgcag atgacggacg ggcacacgag ttgtactgca gtagaattca
      481 gttacatttc aaagataagc ctgaacacac cacctggcac aaaagtgaag ctctccggca
      541 ctgtggacat aaagaacgga ttcctgctgt taagtgactc taataccaca gttcttggtg
      601 gtgaagtgga acacctaatt gacaagtggg cgttacagag aagcttacta aaacacaaca
      661 gaagcaatat tggagctgaa ggtggcccgc ctcctttttt acctttcgga cagaaatgtg
      721 catctactgt ccaagtggat agcagagaac ttgatcgaag aaagacatta caagtttcat
      781 tgcctgccaa acctacaaat gataatgatg agtttgaaaa gcaaaggact gctgccattg
      841 cagaggtcgc aaagagcaaa gagaccaaga catttggagg aggtggaggt ggagtcagaa
      901 gtcatctcaa tattggtgct ggcgggcacc gaaatcggga ggtttcacag aaggaaaagg
      961 cttccaagtc agagagcaaa aatgaaggtg tctatagaga actggttgat gagaaagcgc
     1021 tgaagcacat aacggaaatg ggcttcagta aggaggcgtc gaggcaagca ctgatggata
     1081 atgccaacaa cctagaggca gccttgaacg tacttctgaa cagcagtaaa cagaagcctg
     1141 tcgtgggtcc tcctcccaga ggtagaggga aaggcagggg gcgagtacga tcagaagatg
     1201 aagaagacct aggaaacgca agaccgtcag caccaagcac attatttgat ttcttggagt
     1261 ctaaaatggg aactctgaat atggaagaac ctaggtcaca gccacagcac ctttatcaag
     1321 gacagcacag agtatcgaat actgagcaaa atgggataaa ggatggcaat caatcaagac
     1381 atcttcctcg gaacgacccc aggcagccga gaaatgagaa acctcctcgc tttcaaagag
     1441 acacccccaa tttgaagtca gccttagaaa acagcgtatt atctagaaat agaggctccg
     1501 aaagaccaag cagttcttca ggttctgatg tgtgggcaga agagaggatc aagtgtgata
     1561 ggccgtattc tagatatgac agaactaaag acgcttcgta tcctttaggt tttcagcaca
     1621 atgatggtgc ttttaaaagg agagataact ctatgcaaaa cagatcagga agaggcccgt
     1681 tgtatgcaga ggcaaaagaa aacccacatc cttcagaatt tgtagattat aataatcaaa
     1741 aacgtgggaa aagagaaaac caaaccagta atcctgatca tttttatgac aggaaatcac
     1801 gaacaatgaa tagtgaagcg tttagtggtc taaaaattga aaaacatttt agtgcaaata
     1861 ctgattatca gaatcctgtc caaagtaata gttttgttgg tgttccaaat ggagaaacag
     1921 atatgcctat gaaaggaaga cgagtaggac caattaagcc agcaggacct gtcacagctg
     1981 tgccctacga tgataaaata ttttataata gtgggcccaa aagaagatct gggccaatta
     2041 agcctgaaaa ggtgatagaa tcatctattc ctgtggagta tgcaaaaatg tggaaacctg
     2101 gagatgaatg ttttgcactt tattgggaag acaacaagtt ttaccgagca gaagttgaag
     2161 ccctgcattc ttcgggcatg acagcggttg tgaagttcac ggactacgga aactacgaag
     2221 aggtgcttct aagcaacatc aagcctgttc agacagaggc atgggaagaa gagggtacct
     2281 atgatcacac cattgagttc cggagagggg gtgacggaca gcctcgaagg tccactcggc
     2341 caacacagca gttttaccag cctcctcgag ctcggaacta atgtgaaagg gtttttgtga
     2401 aggaagaacc actgactgaa agatcctggc agcccattca tagatttcca cttcttcaga
     2461 ctgtgactca acgtgctgga tatgattttt agagaaagaa aaaaaaaata aggaaatttt
     2521 aggggaaaga ttcaacctac acaaagcaag gggggaaata ctgagtctga tagagcaaat
     2581 atctttacaa tggaaaactt ttcttctgcc atcaataaaa ccagtgtgtt attataaaaa
     2641 aaaaaaaaaa aaaaaaaaaa
//
