LOCUS       NM_001106202            4905 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus tudor domain containing 1 (Tdrd1), mRNA.
ACCESSION   NM_001106202 XM_001063929 XM_217641
VERSION     NM_001106202.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4905)
  AUTHORS   Kuramochi-Miyagawa,S., Watanabe,T., Gotoh,K., Takamatsu,K.,
            Chuma,S., Kojima-Kita,K., Shiromoto,Y., Asada,N., Toyoda,A.,
            Fujiyama,A., Totoki,Y., Shibata,T., Kimura,T., Nakatsuji,N.,
            Noce,T., Sasaki,H. and Nakano,T.
  TITLE     MVH in piRNA processing and gene silencing of retrotransposons
  JOURNAL   Genes Dev 24 (9), 887-892 (2010)
   PUBMED   20439430
REFERENCE   2  (bases 1 to 4905)
  AUTHORS   Yamaji,M., Tanaka,T., Shigeta,M., Chuma,S., Saga,Y. and Saitou,M.
  TITLE     Functional reconstruction of NANOS3 expression in the germ cell
            lineage by a novel transgenic reporter reveals distinct subcellular
            localizations of NANOS3
  JOURNAL   Reproduction 139 (2), 381-393 (2010)
   PUBMED   19861488
REFERENCE   3  (bases 1 to 4905)
  AUTHORS   Shoji,M., Tanaka,T., Hosokawa,M., Reuter,M., Stark,A., Kato,Y.,
            Kondoh,G., Okawa,K., Chujo,T., Suzuki,T., Hata,K., Martin,S.L.,
            Noce,T., Kuramochi-Miyagawa,S., Nakano,T., Sasaki,H., Pillai,R.S.,
            Nakatsuji,N. and Chuma,S.
  TITLE     The TDRD9-MIWI2 complex is essential for piRNA-mediated
            retrotransposon silencing in the mouse male germline
  JOURNAL   Dev Cell 17 (6), 775-787 (2009)
   PUBMED   20059948
REFERENCE   4  (bases 1 to 4905)
  AUTHORS   Aravin,A.A., van der Heijden,G.W., Castaneda,J., Vagin,V.V.,
            Hannon,G.J. and Bortvin,A.
  TITLE     Cytoplasmic compartmentalization of the fetal piRNA pathway in mice
  JOURNAL   PLoS Genet 5 (12), e1000764 (2009)
   PUBMED   20011505
REFERENCE   5  (bases 1 to 4905)
  AUTHORS   Reuter,M., Chuma,S., Tanaka,T., Franz,T., Stark,A. and Pillai,R.S.
  TITLE     Loss of the Mili-interacting Tudor domain-containing protein-1
            activates transposons and alters the Mili-associated small RNA
            profile
  JOURNAL   Nat Struct Mol Biol 16 (6), 639-646 (2009)
   PUBMED   19465913
REFERENCE   6  (bases 1 to 4905)
  AUTHORS   Hosokawa,M., Shoji,M., Kitamura,K., Tanaka,T., Noce,T., Chuma,S.
            and Nakatsuji,N.
  TITLE     Tudor-related proteins TDRD1/MTR-1, TDRD6 and TDRD7/TRAP: domain
            composition, intracellular localization, and function in male germ
            cells in mice
  JOURNAL   Dev Biol 301 (1), 38-52 (2007)
   PUBMED   17141210
REFERENCE   7  (bases 1 to 4905)
  AUTHORS   Chuma,S., Hosokawa,M., Kitamura,K., Kasai,S., Fujioka,M.,
            Hiyoshi,M., Takamune,K., Noce,T. and Nakatsuji,N.
  TITLE     Tdrd1/Mtr-1, a tudor-related gene, is essential for male germ-cell
            differentiation and nuage/germinal granule formation in mice
  JOURNAL   Proc Natl Acad Sci U S A 103 (43), 15894-15899 (2006)
   PUBMED   17038506
REFERENCE   8  (bases 1 to 4905)
  AUTHORS   Chuma,S., Hiyoshi,M., Yamamoto,A., Hosokawa,M., Takamune,K. and
            Nakatsuji,N.
  TITLE     Mouse Tudor Repeat-1 (MTR-1) is a novel component of chromatoid
            bodies/nuages in male germ cells and forms a complex with snRNPs
  JOURNAL   Mech Dev 120 (9), 979-990 (2003)
   PUBMED   14550528
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473986.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_217641.4, XM_001063929.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..4905
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q55"
     gene            1..4905
                     /gene="Tdrd1"
                     /note="tudor domain containing 1"
                     /db_xref="GeneID:292129"
                     /db_xref="RGD:1306140"
     exon            1..188
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
     exon            189..521
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
     CDS             218..3739
                     /gene="Tdrd1"
                     /codon_start=1
                     /product="tudor domain-containing protein 1"
                     /protein_id="NP_001099672.1"
                     /db_xref="GeneID:292129"
                     /db_xref="RGD:1306140"
                     /translation="MMPRNNLEASTCKMAEPFNFEKKESKLPPHDSLRSPVPQHNHPN
                     FRLKSPENGNKKNNFLLCEQNKQYLASQEDNSVVSSNPAGINGEVGGSKGDRKTLPTG
                     NPVSLSLGNNSPPNQVKTKPSNAVTPEKSKKSHKLFENALSVNNPALFNSLGPPLRST
                     TCHRCGLFGSLRCSQCKQTYYCSTACQRRDWSSHSTICRPVQQSLHKLEDNKSPFETK
                     TIDVKNEVACPLGVTKEMTAGAERVMFSDLRSLQLRKSMEIKGTVTEFKHPGHFYVQL
                     YSSEVLEYMNQLSASLKETYANMVPEDGYLPVKGEVCVAKYTVDQTWNRAVVEGVDVL
                     QKKAHVLYIDYGNEEIIPVDRIHQLSRSISLFPPSAIKCYVSGVVPAAGEWTEDCVVA
                     VKALLFEQYCSIKVVDISEEEGLTCAVDVVLQSSGKQLDHVLVEMGYGVKPDEPSSKK
                     QSMDPGTSEDTGRLTAENRIGAERNALVPTVLTLNVGDEFCGVVAHIQTPEDFFCQQL
                     QSGHKLAELQESLSEYCSHVTPRSDFYPTIGDMCCAQFSEDDQWYRASVLAYASEESV
                     LVGYVDYGNFEILSLKRLCPIIPKLLDLPMQALNCVLAGVKPSLGMWTPEAICVMRKA
                     VQNRMVTVRVVGMQGTRALVELVDKSVAPHLSASKALLDSGFAIEEKDIVADKGSSAR
                     ASNVPLAVEGAVEVLEWTWVEFTVDETVDVMVCMMHSPGEFYCHCLKDDALKKLDDLN
                     KSLADYCAQKPPNGFKAEVGRPCCACFAGDGNWYRALVKEILPSGNVKVHFVDYGNVE
                     EVTTDQLHAIAPQFLLLPFQGMQCWLVDIQPKNKHWTKEATARFQACVVGLKLQARVV
                     EITENGVGVELTDLSTPYPKIISDVLITEHLVLRCGSPQKDELMSRPANKHNQIDSQS
                     VQASPPAEQWKTIELPVNKTVPANVLEIISPTLFYAIPSEMPENQEKLCVLTAELLEH
                     CNAQKGQPPYRPRTGEACCAKYTNDDFWYRAIVLEASDSDVKVLYADYGNVERLPFSR
                     VQPITASHLQLPFRIIRCSLEGLTELNGSSSQPVMELLRNAMLNQSVALSVKAVSKNV
                     HAVSVEKCSENGMINIAENLVMCGLAENLSSKRESASTKETPHSTDCCCTELQKQIEK
                     HEQILLFLLNNPTNQNKFIEMKKLLQS"
     exon            522..577
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
     exon            578..722
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
     exon            723..828
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
     exon            829..892
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
     exon            893..997
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
     exon            998..1180
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1181..1324
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1325..1496
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1497..1583
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1584..1751
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1752..1859
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1860..2030
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2031..2273
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2274..2411
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2412..2522
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2523..2693
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2694..2966
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2967..3086
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
     exon            3087..3203
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
     exon            3204..3371
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
     exon            3372..3599
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
     exon            3600..3646
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
     exon            3647..3739
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
     exon            3740..4905
                     /gene="Tdrd1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tggacttcgg ggctgcgggg tatggcaaac accggcgtga gtgattagcc ttagagaccg
       61 atcagggcca gcgccctttc gcctttttct gggtcaggcg gcctggtcgc caaggcgcgg
      121 gagctcggtg tcaagatcgc ctcgggcgtg gatcgttagg agccggaagt ccagagctgg
      181 acgttgagac gtcagtgaat gttaagttac atctaatatg atgccacgaa ataatttgga
      241 agcctctact tgtaaaatgg cagaaccatt taattttgag aaaaaggaaa gcaaacttcc
      301 accccacgat tctctaagaa gtcctgtacc acagcataac catcccaatt tcagactgaa
      361 aagcccagag aacggaaata aaaagaacaa ttttttgctt tgtgaacaaa acaaacagta
      421 cttggctagt caggaagaca attcggtggt ctcttcaaac cctgctggta tcaatggaga
      481 agtaggtggg tccaaaggag acaggaagac attaccaaca ggaaacccag tatcattaag
      541 tcttggaaac aattcaccac ctaaccaagt aaaaactaag cccagcaatg ctgtgactcc
      601 tgaaaaatca aaaaaatctc acaagctgtt tgagaatgcc ttgtccgtaa ataacccagc
      661 tctcttcaac tcgttaggac cgcccctgcg gtccacaacc tgccatcgct gtggcctgtt
      721 cgggtcgctg aggtgttccc agtgcaagca gacatattac tgctccacag catgccagag
      781 gagagactgg tcttcccata gcaccatctg tagacctgtg cagcaaagtc tgcataagct
      841 tgaagataat aagtcaccat ttgaaacaaa gaccattgac gtgaagaatg aggttgcctg
      901 tcccctggga gttactaaag aaatgacagc tggtgcagag agagtaatgt tttctgatct
      961 gaggagtctc caactgagga aatccatgga aataaagggc acagttactg aattcaagca
     1021 cccgggtcat ttttatgtcc agttgtattc ctcagaggtt ttagagtaca tgaaccaact
     1081 ctctgcaagt ttgaaagaga catatgcaaa tatggtgcct gaagacggat atcttcctgt
     1141 taagggggaa gtctgtgttg ccaagtacac ggttgatcag acctggaacc gagccgtagt
     1201 agaaggcgtg gacgtgctgc agaagaaggc acatgtcttg tacatcgact acggaaatga
     1261 agagatcatc ccagtcgaca gaatccacca gctaagcaga agtatcagcc tgtttccccc
     1321 ttccgccata aagtgctatg tgtcaggagt cgtccccgct gcgggtgagt ggactgaaga
     1381 ctgtgttgta gctgtcaagg ctctgctgtt cgagcagtac tgctctatca aggtcgtgga
     1441 catctcagag gaggaggggc tcacctgtgc tgtcgacgtc gtgctgcaga gttcaggaaa
     1501 acagctggac catgtgcttg tggaaatggg atatggtgtg aaacctgatg agccgagctc
     1561 caagaagcaa agtatggacc caggcacttc ggaggacact ggaagactga cagctgagaa
     1621 caggatcggg gcagagagaa atgccctggt ccccacagtg ctgactttga atgtgggtga
     1681 cgagttctgt ggtgtagttg cccacatcca gacaccagag gacttctttt gtcagcagct
     1741 gcagagtggc cacaagctcg ccgagcttca ggagtccctc agtgagtact gtagccacgt
     1801 gactccacgc tcagactttt atccaaccat tggggacatg tgttgtgctc agttctcaga
     1861 ggatgaccaa tggtaccgcg cctcggttct ggcctatgct tcagaagaat ctgtcctggt
     1921 tggatatgtc gattatggaa actttgaaat tcttagtttg aaaagacttt gtcccataat
     1981 tccaaagttg ttggatttgc cgatgcaagc tttaaattgt gtgctggcag gagtgaagcc
     2041 atctttagga atgtggactc cagaagccat ttgtgtcatg aggaaggctg tgcagaacag
     2101 gatggtgacc gtgagagtgg tgggcatgca ggggaccagg gccctggtgg agctcgtaga
     2161 caaatcggtg gctcctcacc tcagcgcttc taaagctctg ctagactccg gctttgccat
     2221 cgaggaaaag gacatagtgg cagataaagg cagcagtgcg cgtgcctcga atgttccctt
     2281 ggctgtagaa ggagcagtgg aggtgctgga gtggacgtgg gtcgagttca ccgttgacga
     2341 gactgtggac gtgatggtct gcatgatgca cagccctggg gagttctact gccactgtct
     2401 caaagacgac gccttaaaga agctcgatga cttgaacaag tccttagcag actactgtgc
     2461 acaaaaaccg cccaatggct tcaaggcaga ggtagggcgg ccttgctgtg cctgttttgc
     2521 aggtgacggc aactggtacc gggctctggt caaggagatc ctaccaagtg ggaacgtcaa
     2581 agtacacttt gtggactacg gcaatgttga agaggttacc acagaccaac tgcacgcaat
     2641 agccccccag ttcttactac ttccgttcca agggatgcag tgctggctag tagatataca
     2701 gcccaaaaac aagcattgga caaaagaagc cacagcaaga tttcaagcat gtgtcgtggg
     2761 gcttaaactt caagccagag ttgtggaaat cacggagaat ggggtgggcg ttgaactcac
     2821 cgatctttcc accccctacc ccaaaatcat tagtgacgtt ctcatcacag aacatctggt
     2881 cttaaggtgt ggttcaccac agaaggacga gttgatgagc agacctgcta ataaacataa
     2941 ccagatcgac tcccagagcg tgcaagccag ccctcctgca gagcagtgga agaccataga
     3001 gttgccagtt aacaagactg taccagcaaa tgtactagaa atcataagcc caaccttgtt
     3061 ttatgccatc cccagtgaaa tgccagaaaa tcaagaaaaa ctgtgtgtgt tgacagctga
     3121 attgttagaa cactgtaacg ctcagaaagg ccagccaccc tacagaccac ggacgggaga
     3181 agcctgctgt gctaaataca caaatgatga cttctggtac cgggccattg ttctggaagc
     3241 gtcagactct gatgtgaaag ttctctatgc agattatgga aacgtggaaa gactgccttt
     3301 ttccagagtg cagcccatca ctgccagcca cctgcagctg cccttccgca tcattagatg
     3361 ctcacttgag gggctgacgg agctgaacgg aagcagttcg cagccagtga tggagctgct
     3421 gaggaacgcc atgctgaacc agagtgtggc tctctctgtg aaagcagtct cgaagaatgt
     3481 ccatgcagtg tcagttgaaa aatgttctga aaatggaatg atcaatatag ctgagaatct
     3541 ggtgatgtgt ggcctggcag aaaacctctc atctaaaagg gaaagtgctt caactaaaga
     3601 aacaccgcac agcaccgatt gctgctgcac agagttacag aaacagattg agaaacacga
     3661 acagattctc ctcttcctct taaacaatcc aaccaaccaa aataaattta tagagatgaa
     3721 aaagctgctg caaagctaaa aacatcatcc ctggggaaaa acactcggga agaaggagac
     3781 cacaaaagcc agactagaga aagaattgta tcttgtgttt gttcgctgga actgttgctt
     3841 cctctccttt ccttagtgac ctttgacctc accaccccta cttacttacc ttgttctgtt
     3901 gggtttgttg ccctctccct gattctttcc acaaaataca tgaatcttgc ataagaggtt
     3961 catgtactag ctaggcgtgg tggtgcacac ctgtaatccc agccatgagc agaatgaggc
     4021 aagaagacct caagttcaag gccagcatgg gctacataga tagtttctca ttacaaacaa
     4081 aaccaaacat caagattcaa aaaatgtatg agacgactag gaaggaacat gaggtatctt
     4141 ctactaagag tgcgtgcatg agtgcgcgta tgcgtgtgtg tgtgtgtgta tttgctctac
     4201 tgagtataga agctagagcc tcccgtgtgt taggcaagct ttccctctga gctacagtcc
     4261 cagctctagc atctcgctgt ccttgaaagg ctgggtggct gccctgggcg ggcgggcttc
     4321 agcatggtct gaacatcaca ggcctctgct aatgagatgc tcttggtcat ctgccgcctc
     4381 gtcccctgct gggatctgat tggttctttg cttctgggtg ccatgcttcc tttgtgactt
     4441 gtggccaagg atgtgtgctg ctgctctcat ctgtgctgag acagcttggc ttttcatctt
     4501 cgatcacagc ttcagtcttg gcactaggag gacactttct gcccctgccc tcagaggccc
     4561 tcctgggatt gtctcactag tctgtagtca ttcagactta agctctagaa ataattcact
     4621 attttctcaa acacaaactc cagatatcga tttaaaaatg gagagcacat ttgtcatagt
     4681 tcatgatcac agattgtccc aaccttagcc atgggcagca gtgtgtgcct tcctgacagt
     4741 cccatagtcg ctctggcaat tgtcccacgg tttcagtgct gtgcggcact gtgacaactt
     4801 aatacaacat ccccagcact gatattgatg tgggtgggtt tgttccattt ccttttactg
     4861 gcaatgtgtg tcagctcttc tgttaaatag gacttctcac gtaaa
//
