LOCUS       NM_001401130            4168 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus tectonic family member 1 (Tctn1), mRNA.
ACCESSION   NM_001401130 XM_017598329
VERSION     NM_001401130.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4168)
  AUTHORS   Li,C., Jensen,V.L., Park,K., Kennedy,J., Garcia-Gonzalo,F.R.,
            Romani,M., De Mori,R., Bruel,A.L., Gaillard,D., Doray,B., Lopez,E.,
            Riviere,J.B., Faivre,L., Thauvin-Robinet,C., Reiter,J.F.,
            Blacque,O.E., Valente,E.M. and Leroux,M.R.
  TITLE     MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary
            Transition Zone
  JOURNAL   PLoS Biol 14 (3), e1002416 (2016)
   PUBMED   26982032
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4168)
  AUTHORS   Chih,B., Liu,P., Chinn,Y., Chalouni,C., Komuves,L.G., Hass,P.E.,
            Sandoval,W. and Peterson,A.S.
  TITLE     A ciliopathy complex at the transition zone protects the cilia as a
            privileged membrane domain
  JOURNAL   Nat Cell Biol 14 (1), 61-72 (2011)
   PUBMED   22179047
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4168)
  AUTHORS   Garcia-Gonzalo,F.R., Corbit,K.C., Sirerol-Piquer,M.S.,
            Ramaswami,G., Otto,E.A., Noriega,T.R., Seol,A.D., Robinson,J.F.,
            Bennett,C.L., Josifova,D.J., Garcia-Verdugo,J.M., Katsanis,N.,
            Hildebrandt,F. and Reiter,J.F.
  TITLE     A transition zone complex regulates mammalian ciliogenesis and
            ciliary membrane composition
  JOURNAL   Nat Genet 43 (8), 776-784 (2011)
   PUBMED   21725307
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4168)
  AUTHORS   Reiter,J.F. and Skarnes,W.C.
  TITLE     Tectonic, a novel regulator of the Hedgehog pathway required for
            both activation and inhibition
  JOURNAL   Genes Dev 20 (1), 22-27 (2006)
   PUBMED   16357211
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000012.1.
            
            On Feb 2, 2022 this sequence version replaced XM_017598329.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-429               JAXUCZ010000012.1  39970594-39971022
            430-550             JAXUCZ010000012.1  39974012-39974132
            551-681             JAXUCZ010000012.1  39984164-39984294
            682-833             JAXUCZ010000012.1  39985821-39985972
            834-933             JAXUCZ010000012.1  39988120-39988219
            934-1043            JAXUCZ010000012.1  39990686-39990795
            1044-1064           JAXUCZ010000012.1  39991891-39991911
            1065-1199           JAXUCZ010000012.1  39994495-39994629
            1200-1325           JAXUCZ010000012.1  39995475-39995600
            1326-1411           JAXUCZ010000012.1  39995880-39995965
            1412-1552           JAXUCZ010000012.1  39996741-39996881
            1553-1715           JAXUCZ010000012.1  39997477-39997639
            1716-1835           JAXUCZ010000012.1  40000595-40000714
            1836-4168           JAXUCZ010000012.1  40001395-40003727
FEATURES             Location/Qualifiers
     source          1..4168
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q16"
     gene            1..4168
                     /gene="Tctn1"
                     /gene_synonym="RGD1566266"
                     /note="tectonic family member 1"
                     /db_xref="GeneID:304486"
                     /db_xref="RGD:1566266"
     exon            1..429
                     /gene="Tctn1"
                     /gene_synonym="RGD1566266"
                     /inference="alignment:Splign:2.1.0"
     CDS             72..1979
                     /gene="Tctn1"
                     /gene_synonym="RGD1566266"
                     /note="tectonic-1"
                     /codon_start=1
                     /product="tectonic-1 precursor"
                     /protein_id="NP_001388059.1"
                     /db_xref="GeneID:304486"
                     /db_xref="RGD:1566266"
                     /translation="MGSRCLPPLLLVLLNCCTSSSTQVVATPAAATPVVTNEDLNFTE
                     ATPVVTNEDLNFTEATPVVTNEDLNFTEATPVVTNEDLNFTEATPATLRPSWSPRTPG
                     TPRPPELSGPRPTPVTDVAALCVCDLLPAQCDINCCCDPDCSPGDFSVFSACSIPVVT
                     GDRQFCSQKAAFYSMNLTADPPHRDFKLIDQINPSIFCIHISNYKPALSFANPEVPDE
                     NNFDRLMGASGGFTLSAESGVPSTATSDDPQPTKYEYGALLQTAGESSGSFLKLPSPL
                     TSSLCADENPAAFLVNQAFECSRRVAIEECERMEALSMAHYSSPAILRVPNSTTQVSI
                     KIQSIMYRSLNHTLTQLEGRGILRPSLVSTGQDRLCSNVVLQVKYSLLYTASGQIQEA
                     GLSLVLGTLISTVSLLQQKFEIHFIQHGTKPVPLSGNPGYRVGLPLAAGFQPQKGSGI
                     IQTTNRQGQLTILRSTGKQDCLASHGQRAPVLFGYNVQSGCQLRLTGTIPCGLLAQKM
                     QDLLRGQAFPDYVAAFGNSRAQDVQDWVPVHFVTHSSNTKGSCQLPVALGIEVKWTKY
                     GSLLNPQARIVNVTAQLISIPEPLPGPERTMVISTAVTFVDVSAPAEAGFRAPPTINA
                     RLPFSFFFPFV"
     exon            430..550
                     /gene="Tctn1"
                     /gene_synonym="RGD1566266"
                     /inference="alignment:Splign:2.1.0"
     exon            551..681
                     /gene="Tctn1"
                     /gene_synonym="RGD1566266"
                     /inference="alignment:Splign:2.1.0"
     exon            682..833
                     /gene="Tctn1"
                     /gene_synonym="RGD1566266"
                     /inference="alignment:Splign:2.1.0"
     exon            834..933
                     /gene="Tctn1"
                     /gene_synonym="RGD1566266"
                     /inference="alignment:Splign:2.1.0"
     exon            934..1043
                     /gene="Tctn1"
                     /gene_synonym="RGD1566266"
                     /inference="alignment:Splign:2.1.0"
     exon            1044..1064
                     /gene="Tctn1"
                     /gene_synonym="RGD1566266"
                     /inference="alignment:Splign:2.1.0"
     exon            1065..1199
                     /gene="Tctn1"
                     /gene_synonym="RGD1566266"
                     /inference="alignment:Splign:2.1.0"
     exon            1200..1325
                     /gene="Tctn1"
                     /gene_synonym="RGD1566266"
                     /inference="alignment:Splign:2.1.0"
     exon            1326..1411
                     /gene="Tctn1"
                     /gene_synonym="RGD1566266"
                     /inference="alignment:Splign:2.1.0"
     exon            1412..1552
                     /gene="Tctn1"
                     /gene_synonym="RGD1566266"
                     /inference="alignment:Splign:2.1.0"
     exon            1553..1715
                     /gene="Tctn1"
                     /gene_synonym="RGD1566266"
                     /inference="alignment:Splign:2.1.0"
     exon            1716..1835
                     /gene="Tctn1"
                     /gene_synonym="RGD1566266"
                     /inference="alignment:Splign:2.1.0"
     exon            1836..4168
                     /gene="Tctn1"
                     /gene_synonym="RGD1566266"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcgctcggc tgtgactgtt gcccggcaac agacaggcct agctctctgg cgcgggatag
       61 tatgctagtc catggggtcg cggtgtcttc cgccgctcct gctggtgctc ctaaactgct
      121 gcacctcttc gagcacccag gtcgttgcca ccccggctgc ggccaccccg gtggtgacga
      181 atgaggatct caacttcacc gaggccaccc cggtggtgac gaatgaggat ctcaacttca
      241 ccgaggccac cccggtggtg acgaatgagg atctcaactt caccgaggcc accccggtgg
      301 tgacgaatga ggatctcaac ttcaccgagg ccacccccgc cactctcaga ccctcctggt
      361 ctcctaggac cccgggaact cccaggccac cggagctctc tggccccagg cccaccccgg
      421 tcacggacgt tgctgctctg tgtgtctgcg acctgcttcc tgcacagtgt gatatcaact
      481 gctgttgtga ccctgactgc agccctgggg atttcagcgt cttctctgcc tgctccatcc
      541 cagttgtcac gggtgatcgg cagttttgta gtcagaaggc agccttctac tcaatgaatt
      601 tgacagcaga cccacctcac cgcgacttta aactcattga ccagatcaac ccttccatct
      661 tctgtattca tatttcaaac tacaagccgg cgctgtcttt tgccaatccg gaagtgccag
      721 atgaaaacaa ttttgataga ctgatgggag catcaggtgg ctttacactg agtgccgagt
      781 caggagttcc ttccacagcc acctcagatg acccacagcc cactaaatat gagtatggag
      841 cccttctgca gaccgcaggt gaatcttcag ggtcatttct gaaactgcct tcacctctca
      901 cttcatctct gtgtgcagat gagaaccctg cagcattcct ggtgaaccag gccttcgaat
      961 gcagccgaag ggtggccata gaagagtgtg aaagaatgga agctctcagc atggctcact
     1021 acagcagccc tgccattctg agggtgccta attcaacgac acaggtctcc atcaagatcc
     1081 agtctataat gtatcggtct ctgaatcaca cactgaccca gttagaaggc cgtggtatcc
     1141 tgcggccatc tctggtcagc actgggcaag acagactctg cagcaacgtt gttctccagg
     1201 taaagtacag tctgctatac acagccagcg gccagatcca ggaagccggc ctctccctcg
     1261 tgctggggac gctcatcagc accgtgagtc tcctgcagca gaagtttgag attcacttta
     1321 ttcagcatgg caccaagcct gttcctctca gtggcaaccc tggttacaga gtgggactcc
     1381 cgctggccgc tggctttcag cctcagaagg ggtctgggat tattcagaca acgaacagac
     1441 aaggccagct tactattctt cgtagcacag gcaagcagga ctgcctggcc agccacgggc
     1501 agcgggctcc tgtgctgttt ggctacaatg tgcagtctgg ctgtcagctc aggttgacag
     1561 gcaccatccc atgcgggctt ctggcacaga agatgcagga tctgctgaga ggccaggcct
     1621 tccctgacta cgtggctgcg tttgggaact cacgagccca ggatgtgcag gactgggtgc
     1681 ctgtgcactt tgtcacccac tcctccaaca cgaagggctc ttgccagctt cctgtggctt
     1741 tgggtataga agtaaaatgg actaagtatg ggtccctgct gaacccccag gccaggatag
     1801 taaatgtcac tgcccagctc atctcaattc cagagcccct cccagggcct gagaggacca
     1861 tggtcatttc cactgcagtg acatttgtgg atgtgtcagc ccctgcagag gcaggcttcc
     1921 gagccccacc caccatcaat gccaggctgc ccttcagctt cttcttccca tttgtatgat
     1981 gaggtggccc ccacacgggt gagtacccat catgagggct tccctttggc agcagtgggc
     2041 acctgggccc caagctcagg aggacaggaa cctcgctgcc acttccctta aagcagccct
     2101 ctgccctgtc cactgccttc tccctctcag aagctttgct ctgctgggca ttgggtcaga
     2161 tggtccagca cacacaggtc aaaggcggag tcacctctgg gagacaggag ggagcaagcc
     2221 tgatgcagca gtgcgtggga cgcctcctcg gtgcatcatt cctggtctag tgggagctga
     2281 ctttagaacg cccgtcagca tctgaagtac agacctgcaa gaggctgtgt aaaaccatgt
     2341 gccccaaggg agttgtaccc caagagcatg ctaattgcag ggcagtcttg gggccctgcc
     2401 gtgagctggc tggataactg gtgggctggt gtgggctgcc actgaggaga atgtggtagg
     2461 cgagccctgg ggaaggagag cctattatac attaattgta cagtaactga aagatgctgg
     2521 tgggtgcaga gccagttcga agctgacggt acagccggat gctgcagtgg ggctgggtac
     2581 catgatggct ccccagggac tgcagcagga gaagctgtgg accgtctagt aaagaaaggg
     2641 tttgcaggat gggctggcac agggcacagg ctccagcccc atcccagatg tgtgtcaagt
     2701 tggtttgcaa gtccagcttt ctccatttcc aagcaacaga gtccagcttg agaaaaggtt
     2761 gttatgattc ctttgctgca ggcgtagggc atggacacgg aggagacagc tgtggccatg
     2821 aagatttgtc cccagcatcc aggagtgcaa gccaaggcag agatgggtgg ggactggacc
     2881 tcaaaccaca cagttgctct ctggacacag cccagctctg gatggagctt ctggaaggct
     2941 tagttcacgt tcacgtcctc aagaagtccg ttctgtctca acagcttgct cagtcgctca
     3001 atttcttgtt cctattgtaa aagcaaacgc acacagggtg atgaccttct gagctacatt
     3061 tcccccaggc ccagggctgc agatagctag aagctacagt ctgtggcatt ctggctgctg
     3121 aaggaaaccc ctttcaggaa gggccctggg cagtgatagc aggagcaaga tgcccagagg
     3181 agggactgga cctggctctt gaagcccata ctgaagctga aaagaccaag aagagggagc
     3241 tacatgtcag catgggctgg aggggaccgc agtggaacca cttgtctcac cttctcggag
     3301 cagctgaatt ccagatgctg gatcttggtg gccagttgga ggtttatctg ctttaaccgt
     3361 aagatctgcc gttcagagcg tgtcttcact gagatgatga tacctagaag ggagaggagg
     3421 gttttggtga tgcaacaact tcattgtaaa cgtgtgagag aggggtaggg ggatggggtg
     3481 catgtgcacc acagagtctg tggacgtcaa aggacaagac ctgggaagtc tgtctttcct
     3541 gtcaccatgt gtgtcctatg gctaaactca ggtcaccaag cctagtggca agagtcagcc
     3601 ccacaacttg tgctgactca cacatagagt tgggcatgta gacaactgtc actgggcagc
     3661 ctcggtgaga aagacaaggc ggttatttct gagctcagag taagcagcta ggcagtattt
     3721 ccctatggcc tgcatgggtg ctgagtctct acaagctagc tgtgttcccg ttccccaagg
     3781 acatttgtcc ctagcagtaa gagaaagctg cttgtcttcc ctggtcagag tccatccaga
     3841 gtgtggagat aaaaggcagg agttaaggca gggactccct gccgtaggcc agccctgact
     3901 ggctgacacc tggcctgctg gcttggggaa gccttgcacg gctccagaga cccagctcct
     3961 gccccactag cagtgctgcc cctcatgcag acccagagag gcccaggcgt gcacccgagt
     4021 tacctgaccc agctgcagtg ggaggcttcc acccatctca gccaaggcac ccctgtcagg
     4081 gagcctactc tgtggctgca ctatgtgata aatgtaataa atctttatgt ctgccttttg
     4141 ataaattcat taaaaccttt ttttttaa
//
