LOCUS       NM_001109601            1324 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus Tcl1 family Akt coactivator A (Tcl1a), mRNA.
ACCESSION   NM_001109601 XM_001074847
VERSION     NM_001109601.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1324)
  AUTHORS   Nishimura K, Aizawa S, Nugroho FL, Shiomitsu E, Tran YTH, Bui PL,
            Borisova E, Sakuragi Y, Takada H, Kurisaki A, Hayashi Y, Fukuda A,
            Nakanishi M and Hisatake K.
  TITLE     A Role for KLF4 in Promoting the Metabolic Shift via TCL1 during
            Induced Pluripotent Stem Cell Generation
  JOURNAL   Stem Cell Reports 8 (3), 787-801 (2017)
   PUBMED   28262547
REFERENCE   2  (bases 1 to 1324)
  AUTHORS   Loh YH, Zhang W, Chen X, George J and Ng HH.
  TITLE     Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate
            self-renewal in embryonic stem cells
  JOURNAL   Genes Dev 21 (20), 2545-2557 (2007)
   PUBMED   17938240
REFERENCE   3  (bases 1 to 1324)
  AUTHORS   Ivanova N, Dobrin R, Lu R, Kotenko I, Levorse J, DeCoste C, Schafer
            X, Lun Y and Lemischka IR.
  TITLE     Dissecting self-renewal in stem cells with RNA interference
  JOURNAL   Nature 442 (7102), 533-538 (2006)
   PUBMED   16767105
REFERENCE   4  (bases 1 to 1324)
  AUTHORS   Narducci MG, Fiorenza MT, Kang SM, Bevilacqua A, Di Giacomo M,
            Remotti D, Picchio MC, Fidanza V, Cooper MD, Croce CM, Mangia F and
            Russo G.
  TITLE     TCL1 participates in early embryonic development and is
            overexpressed in human seminomas
  JOURNAL   Proc Natl Acad Sci U S A 99 (18), 11712-11717 (2002)
   PUBMED   12181493
REFERENCE   5  (bases 1 to 1324)
  AUTHORS   Laine J, Kunstle G, Obata T, Sha M and Noguchi M.
  TITLE     The protooncogene TCL1 is an Akt kinase coactivator
  JOURNAL   Mol Cell 6 (2), 395-407 (2000)
   PUBMED   10983986
REFERENCE   6  (bases 1 to 1324)
  AUTHORS   Pekarsky Y, Hallas C, Isobe M, Russo G and Croce CM.
  TITLE     Abnormalities at 14q32.1 in T cell malignancies involve two
            oncogenes
  JOURNAL   Proc Natl Acad Sci U S A 96 (6), 2949-2951 (1999)
   PUBMED   10077617
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473982.1.
            
            On Oct 4, 2007 this sequence version replaced XM_001074847.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760383 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1324
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q32"
     gene            1..1324
                     /gene="Tcl1a"
                     /gene_synonym="Tcl1"
                     /note="Tcl1 family Akt coactivator A"
                     /db_xref="GeneID:690575"
                     /db_xref="RGD:1594686"
     exon            1..181
                     /gene="Tcl1a"
                     /gene_synonym="Tcl1"
                     /inference="alignment:Splign:2.1.0"
     CDS             62..400
                     /gene="Tcl1a"
                     /gene_synonym="Tcl1"
                     /note="T-cell leukemia/lymphoma protein 1A (P14 TCL1
                     protein) (TCL1 oncogene) (TCL-1 protein); T-cell lymphoma
                     breakpoint 1; T-cell leukemia/lymphoma 1A"
                     /codon_start=1
                     /product="T-cell leukemia/lymphoma protein 1A"
                     /protein_id="NP_001103071.1"
                     /db_xref="GeneID:690575"
                     /db_xref="RGD:1594686"
                     /translation="MANQLAYRPETPPHPDRLWLWEKHVYLDEFRRSWLPIVIKSNGK
                     FQVIMRQKDVILGDSMTPSQLVPYELPLMWQLYPEERYRSSNSEFWQIVYHIKFKDDE
                     DMLLELLDSE"
     exon            182..352
                     /gene="Tcl1a"
                     /gene_synonym="Tcl1"
                     /inference="alignment:Splign:2.1.0"
     exon            353..412
                     /gene="Tcl1a"
                     /gene_synonym="Tcl1"
                     /inference="alignment:Splign:2.1.0"
     exon            413..1324
                     /gene="Tcl1a"
                     /gene_synonym="Tcl1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaagtcgct ttatcacgga ctggcattgc aattttttgc ttcttgctcc gaccggatgc
       61 catggctaac cagctggcat acaggccaga gacaccccca caccccgacc gcctgtggct
      121 ctgggagaag cacgtgtact tggatgaatt tcgtcgcagc tggttgccga tagtcatcaa
      181 gagtaacgga aaattccagg tgatcatgcg acagaaagat gtcatcttgg gggattccat
      241 gaccccaagt cagctggtgc cgtatgagct gcctttaatg tggcagctat accctgagga
      301 aaggtaccga agcagtaact ccgagttctg gcagatagtg taccacatca agttcaaaga
      361 tgatgaggac atgctacttg aactgttgga ctctgagtaa cgttgagaca tggccctgca
      421 gctcctgtct cccttgccca ggcctgagcc cacaggggag atgctggtac ttacatttgc
      481 tctgttggct aggcatgttc tttctcctcc acactgggct ccaagaagaa aagtccatcc
      541 agaggctgcc ccttcccatg ttcctgtcgc ccgctctgct gccttggttg gcccttccac
      601 tctaccggct ccctggcaag gggttcaggg aagatcccca ttctcctcac ctcctctagg
      661 tgcccagtgg tgtctgcacc tctgatcttc tcagctgatt gatttttttt ttctgccttt
      721 cccttttgcc tctcaagaca actagtgtct ggcttgccag tttgccttcc caaggggccc
      781 tcagttgtac atatgccatg agggacgaga ccaagtcatt tgaatccggc agaccccagg
      841 tccgccatct ctcaaggtgt gctgtggcgc ctgtacccac ctggcctgtg aaccgtcacc
      901 tacccaacaa atgcagacgt ggttggaaag cagtttaaga ccagagagct ccatttccct
      961 gtcgtagaac ccgggtgctt gcagccaggg atatgcaaac ctcactagag caggaggcca
     1021 gggaatggag ctgatttaga tgagccctta gcttgcccac tcttggcctc tctcccttgg
     1081 tgttcagata ctgtattgaa tataagcact tcctgttaac cgattaaata tctcactcac
     1141 ctaagttggg ccgaactggc ttctatcctt gaccaagatg ccaagaaata agagagaaga
     1201 ctgctctggg ttctcccaga gaagccgtgg tcttccagta agaatgttga aagggaatgt
     1261 gtgggatttt atatgtttct attttagaga taaggccaga cttaataaag ctttatagaa
     1321 ctct
//
