LOCUS       NM_001400950            5042 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus transcription factor 25 (Tcf25), transcript
            variant 1, mRNA.
ACCESSION   NM_001400950 XM_214707
VERSION     NM_001400950.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5042)
  AUTHORS   Cai,Z., Wang,Y., Yu,W., Xiao,J., Li,Y., Liu,L., Zhu,C., Tan,K.,
            Deng,Y., Yuan,W., Liu,M. and Wu,X.
  TITLE     hnulp1, a basic helix-loop-helix protein with a novel
            transcriptional repressive domain, inhibits transcriptional
            activity of serum response factor
  JOURNAL   Biochem Biophys Res Commun 343 (3), 973-981 (2006)
   PUBMED   16574069
REFERENCE   2  (bases 1 to 5042)
  AUTHORS   Olsson,M., Durbeej,M., Ekblom,P. and Hjalt,T.
  TITLE     Nulp1, a novel basic helix-loop-helix protein expressed broadly
            during early embryonic organogenesis and prominently in developing
            dorsal root ganglia
  JOURNAL   Cell Tissue Res 308 (3), 361-370 (2002)
   PUBMED   12107429
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000313.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001400950.2.
            
            On Jan 31, 2022 this sequence version replaced XM_214707.10.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ215148.1, SRR8487227.151581.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-242               JACYVU010000313.1  28460965-28461206
            243-407             JACYVU010000313.1  28468538-28468702
            408-482             JACYVU010000313.1  28469709-28469783
            483-601             JACYVU010000313.1  28470490-28470608
            602-667             JACYVU010000313.1  28471560-28471625
            668-750             JACYVU010000313.1  28475915-28475997
            751-881             JACYVU010000313.1  28476951-28477081
            882-981             JACYVU010000313.1  28477996-28478095
            982-1075            JACYVU010000313.1  28478780-28478873
            1076-1168           JACYVU010000313.1  28480220-28480312
            1169-1274           JACYVU010000313.1  28480431-28480536
            1275-1434           JACYVU010000313.1  28482470-28482629
            1435-1522           JACYVU010000313.1  28483671-28483758
            1523-1681           JACYVU010000313.1  28488328-28488486
            1682-1772           JACYVU010000313.1  28489506-28489596
            1773-1852           JACYVU010000313.1  28490215-28490294
            1853-1925           JACYVU010000313.1  28491540-28491612
            1926-5042           JACYVU010000313.1  28491977-28495093
FEATURES             Location/Qualifiers
     source          1..5042
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q12"
     gene            1..5042
                     /gene="Tcf25"
                     /gene_synonym="RGD1309054"
                     /note="transcription factor 25"
                     /db_xref="GeneID:292082"
                     /db_xref="RGD:1309054"
     exon            1..242
                     /gene="Tcf25"
                     /gene_synonym="RGD1309054"
                     /inference="alignment:Splign:2.1.0"
     CDS             51..2084
                     /gene="Tcf25"
                     /gene_synonym="RGD1309054"
                     /note="isoform 1 is encoded by transcript variant 1;
                     transcription factor 25 (basic helix-loop-helix)"
                     /codon_start=1
                     /product="ribosome quality control complex subunit TCF25
                     isoform 1"
                     /protein_id="NP_001387879.1"
                     /db_xref="GeneID:292082"
                     /db_xref="RGD:1309054"
                     /translation="MSRRALRRLRGEQRGQEPLGPDALQFVLLDDDDAEEEGPKTGLG
                     GRRPGGAGKEGVRVNNRFELINIEDLEDDLVVNGERSDCTLPDSASSGNKGRAKHGNP
                     ENKQDGDAAAKAGSSEQSNASGKLRKKKKKQKNKKSCTGESSENGLEDIDRILERIED
                     SSGFSHPGPPPLSSRKHVLYVEHRHLNPDTELKRYFGARAVLGEQRPRQRQRVYPKCT
                     WLTTPKSTWPRYSKPGLSMRLLESKKGLSFFAFEHSEEYQQAQHKFLVAVESMEPNNI
                     VALLQTSPYHVDSLLQLSDACRFQEDQEMARDLIERALYSMECVFHPLFSLTSGTCRL
                     DYRRPENRSFYLALYKQMSFLEKRGCPRTALEYCKLILSLEPDEDPLCMLLLIDHMAL
                     RARNYEYLIRLFQEWEAHRNLSQLPNFAFSVPLAYFLLSQQTDLPDHELSSARQQASL
                     LIQQALTMFPGVLMPLLEYCSVRPDATVSNHRFFGPDAEISQPPALSQLVSLYLGRSH
                     FLWKEPAIMSWLEENVHEVLEAVDSGDPAVEACENRRKVLYQRAPRNIHRHVILSEIK
                     EAVAALPSDVTTQSVMGFDPLPPVDTIYSYVRPERLSPVSHGNTIALFFRSLLPNYTT
                     EGERLEEGVAGGPNRNQGLNRLMLAVRDMMANFHFNDLEVPREDNPEGEGDWD"
     exon            243..407
                     /gene="Tcf25"
                     /gene_synonym="RGD1309054"
                     /inference="alignment:Splign:2.1.0"
     exon            408..482
                     /gene="Tcf25"
                     /gene_synonym="RGD1309054"
                     /inference="alignment:Splign:2.1.0"
     exon            483..601
                     /gene="Tcf25"
                     /gene_synonym="RGD1309054"
                     /inference="alignment:Splign:2.1.0"
     exon            602..667
                     /gene="Tcf25"
                     /gene_synonym="RGD1309054"
                     /inference="alignment:Splign:2.1.0"
     exon            668..750
                     /gene="Tcf25"
                     /gene_synonym="RGD1309054"
                     /inference="alignment:Splign:2.1.0"
     exon            751..881
                     /gene="Tcf25"
                     /gene_synonym="RGD1309054"
                     /inference="alignment:Splign:2.1.0"
     exon            882..981
                     /gene="Tcf25"
                     /gene_synonym="RGD1309054"
                     /inference="alignment:Splign:2.1.0"
     exon            982..1075
                     /gene="Tcf25"
                     /gene_synonym="RGD1309054"
                     /inference="alignment:Splign:2.1.0"
     exon            1076..1168
                     /gene="Tcf25"
                     /gene_synonym="RGD1309054"
                     /inference="alignment:Splign:2.1.0"
     exon            1169..1274
                     /gene="Tcf25"
                     /gene_synonym="RGD1309054"
                     /inference="alignment:Splign:2.1.0"
     exon            1275..1434
                     /gene="Tcf25"
                     /gene_synonym="RGD1309054"
                     /inference="alignment:Splign:2.1.0"
     exon            1435..1522
                     /gene="Tcf25"
                     /gene_synonym="RGD1309054"
                     /inference="alignment:Splign:2.1.0"
     exon            1523..1681
                     /gene="Tcf25"
                     /gene_synonym="RGD1309054"
                     /inference="alignment:Splign:2.1.0"
     exon            1682..1772
                     /gene="Tcf25"
                     /gene_synonym="RGD1309054"
                     /inference="alignment:Splign:2.1.0"
     exon            1773..1852
                     /gene="Tcf25"
                     /gene_synonym="RGD1309054"
                     /inference="alignment:Splign:2.1.0"
     exon            1853..1925
                     /gene="Tcf25"
                     /gene_synonym="RGD1309054"
                     /inference="alignment:Splign:2.1.0"
     exon            1926..5042
                     /gene="Tcf25"
                     /gene_synonym="RGD1309054"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actctgctgc tcttcctcgt ccctctgcct acatctggtt gtcgggtcct atgtcgcgcc
       61 gggccctccg gagactgagg ggggaacagc gcggccagga acccctaggg cccgacgccc
      121 tgcagtttgt cctccttgat gacgatgacg cagaggaaga gggaccaaaa acggggctgg
      181 gtggccggcg ccccgggggt gcagggaagg aaggagtccg tgtcaacaac cggttcgagc
      241 tgataaacat tgaggacctt gaggatgacc ttgtggtaaa tggggagagg tctgactgta
      301 ccctgccaga ctctgcatca tcagggaaca aaggaagggc taaacatgga aacccagaga
      361 acaagcagga tggagatgct gcagccaaag cagggtcctc ggaacagtct aatgcaagtg
      421 gcaaactccg aaagaagaaa aagaagcaga aaaataagaa aagctgcaca ggagaatcct
      481 cggagaatgg actagaagac attgatcgca tcttagagag gattgaagac agcagtgggt
      541 tcagccaccc aggcccccct ccactgagct ccaggaagca tgtcctgtat gtggagcaca
      601 gacacttgaa tccagacacc gaactgaaga gatattttgg tgctcgagcg gtcctgggtg
      661 agcaaagacc tcggcagaga cagcgcgtgt atcccaagtg tacatggctg acgaccccta
      721 agagcacctg gccccgatac agcaaaccag gtctgtcaat gcggctgctg gagtccaaga
      781 aaggcctttc tttctttgca tttgagcaca gtgaagaata ccaacaagca cagcacaagt
      841 tcctggtggc tgtggagtcc atggagccaa acaacatcgt ggctctgctc cagacaagcc
      901 cctatcatgt cgactcactt cttcagctca gtgatgcctg ccgctttcag gaggatcagg
      961 agatggctcg agacctgatc gagagagccc tgtacagcat ggagtgtgtg ttccacccct
     1021 tgttcagcct caccagtggg acttgcaggc tggattaccg cagacctgag aacaggagct
     1081 tctacctggc cctctacaag cagatgagct tcttggagaa gcgtggctgc ccacgtactg
     1141 cactcgagta ctgcaagctc atcctgagcc ttgagccgga tgaggacccc ctgtgcatgc
     1201 tgctgctcat tgaccacatg gccttgcggg cccggaatta tgagtacctg atccgcctct
     1261 tccaggagtg ggaggcccat cggaacctgt cccagctccc aaattttgcc ttctcagttc
     1321 cattggcgta tttccttctg agtcagcaaa cagacttacc tgatcatgag ctcagctctg
     1381 ccaggcaaca ggcttccctc ctgatacagc aggcgctcac catgttccct ggagttctta
     1441 tgccattgct ggagtattgc agtgtacgac ctgacgccac agtctcaaac caccgcttct
     1501 ttgggccgga tgccgagatc agccagcctc ctgccctgag ccagctggtg agtctgtacc
     1561 ttgggaggtc acactttctt tggaaagagc ccgctatcat gagctggctg gaggaaaatg
     1621 tccacgaagt tctggaagca gtggattctg gagaccctgc cgtggaggcc tgtgagaaca
     1681 ggcggaaagt gctgtaccag cgtgcaccca gaaacatcca ccgccatgtg atcctgtctg
     1741 agatcaagga ggctgtcgct gccctaccct cggatgtgac cacacagtct gttatggggt
     1801 ttgaccctct gcctcccgtg gacaccatct actcctacgt cagaccggag aggctgagtc
     1861 cagtcagcca cggaaacaca atcgccctct tcttccggtc attattgcca aattacacca
     1921 cagaggggga gaggctggag gaaggagtgg ccgggggtcc gaaccgcaat caaggcttga
     1981 acaggctgat gttggccgtg cgtgacatga tggccaactt ccacttcaac gacctggagg
     2041 tgcctcggga ggacaatcct gagggcgagg gggactggga ctgaactgtt cagacactgt
     2101 gcccagagct gtgcaatcat gttcctgatt tcgtttctgg ttggagttaa ccagttccca
     2161 agtagaaatg ctgaccatgc catcacgtgt gtttttttct ccctctaaat ggagtgggtt
     2221 atgctctgtg agtgagcgtc ctccagtgtc ctcggaaata gccccagaag ccgtgagccc
     2281 cacactgaat gaaccatgtg cctcacactt tggagttggt aacatggtgc agagaagggt
     2341 tttccccgag tccgcagtac caggacccta cctgctcctt gctaagggca ctgaaccttc
     2401 acacatgcta cacccagcat gttggcagtg ctggggtcaa acccagggcc tggcacacaa
     2461 tctaccactg aatgacagtc ccagcctgag gatcttacta gaaaacttgg agggctggaa
     2521 atgtgtctca gctagtagac tgtttgcttc gtgtgcacaa cccttaggat tcgatctcca
     2581 gcacagcaca aaccagcagt gtgagtgttc atgtgtactc agcacccaag cacagagcgc
     2641 aagaggatta agagttcaga accatcctct gctatagtga gctcagagcc ggtcttagtt
     2701 ccatgagatc ccatctcaac aaagggttgg ggcatgaggg gcctaggata ggaagagaag
     2761 taaaaaaaaa aaaaaaaaaa aaaagtttga agcaggaaat tgtcctaagc aggtaagaaa
     2821 tactttacag agattaaagg gtgtttgatc tagggatgag tggagaaccc tgaccaagaa
     2881 ccccagtcca gggacggacg aagactacag ccaggcaagg cctgaggccc gtgtctcata
     2941 agccatctgt ctgtggaaag atccaggctg ccgaggttac aggctgtcag gtctctctag
     3001 gcagtgctga gggtttgcac cccagcagag gctggaggag gcacccatgg gctcttgtct
     3061 gggagcaggg tcttagctgt gtgagggcca gtgagggctc ctaagccttg gtccaatgat
     3121 gccttcctgg gagtctacat gtttccgata tcactggatg atttactatg gagtaggaac
     3181 aaataaagca tgatttagga gtgtcctgag ctatcacaat ggctcagtga gtataggcac
     3241 tggctgcgtc caatccccag gcctcccaca gtggacagtg agagccaact cctgtagctt
     3301 gtcttctgac ctccacacac atgcacatgt gcacaccgac ggaaatacac ccaagaaatg
     3361 gaaaagggat ggcttgggtt aaagcactgt gcagaggacc aggctgggaa cttaagcaca
     3421 catggtaggt gactcataac tacccataat tccagctcca gcgaacaaac aagggcatag
     3481 aaattaagaa aaatactttt aggggttggg gatttagctc agtggtagag cgcttgccta
     3541 gcaagcgcaa ggccctgggt ttggtcccca gctccggaaa aaaaaaaaaa aaaaaaagat
     3601 tttaacaggt gctctggggc aaggggtcct agatgtgact gaacagggtc ccagagcact
     3661 gccccttcta caggatatcg agggctgact ggtacccatc tatagtcagc ctatgtgtca
     3721 tagcccattt ttttttaagt ttatttattt attatattta agtacactgt agctgtcttc
     3781 agacacacca gaagagggca tcagatctca ttccagatgg ctgtgagcca ccatgtggtt
     3841 gctgggattt gaactcagga cctctggaag agcagttagt gctcttaacc actgagccat
     3901 ctctccagcc ctcatagccc atttctaagt tggccatttg caggagggac tccgtgttca
     3961 acgtgcattc ttggtaagag gtcacaggtc acaggtcaca tgaattggtg ctgtatctct
     4021 gtgtttttct ccagcatgag ttggcaaggc catgaagtct ggatgcaggt tctgctactt
     4081 ttgctcgtgg gtcagcagga cctggggaag gcaggcctga ggggcatagc tcctaccatt
     4141 tgcctaccca ctcctgggtt tggtgggatg gtcataccct gtcccaggga gggttactgc
     4201 ggagatagat ggtcctaact caatgtgtaa atcccagttt ccgagttgga atgccctgtg
     4261 gtgagtttga gctgagggga ggagggaggg attgcctagg aatggggtgt gttctggaaa
     4321 tgacaagcaa gcacagaaaa cctggcatcc tgcctcttcc tttcagcagc tgtaagtcca
     4381 tccagatgag gatgtgacat ctggagctgc agcagctgtt ctgcaacctc gagacaacac
     4441 attccaaaat gaagagtcac actctagaaa cagtgaagca gaggatgccc taggccttcg
     4501 gaaccatccc acctccaggc ctgtctcctg agaggccgtc gatggtcagc ctcagcctca
     4561 gaactgttgc tcagactttc aactgaatcc atttctaatg gtgaaaaata aaaccagtcc
     4621 ctcacaccat ctgtggatca tcatcgggaa aagtaacttt ttgagacagg gtctcactgt
     4681 gtagcccgta gtggcctgga gcttgctctg tagtccaggc tgcccttgct ctgtagacca
     4741 ggctggcctc agatcagcct gcctctgtct cccaaatgtt aggattaaaa gagtgtacca
     4801 ccacacctaa cctgcatgtc atcgaaacag ctttaaagtc tggcctgtcg cccaggtagg
     4861 ggcgatagtg tatcccgctc ctcccgctcc tccctggtcc ctcctcagtc tcacaagagg
     4921 tgcctgccta tgtgtcctgt gcagaattgt gggttctttg tgcatttcca tgtagtcagg
     4981 gagaaaactt gtttgttgcc tctcagagaa agttcaaaag aaatgaaaga ctttcaaaca
     5041 aa
//
