LOCUS       NM_001032397            1245 bp    mRNA    linear   ROD 02-MAY-2023
DEFINITION  Rattus norvegicus transcription factor 21 (Tcf21), mRNA.
ACCESSION   NM_001032397 XM_341737
VERSION     NM_001032397.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1245)
  AUTHORS   Zhang X, Huang J, Li J, Lu Q, Huang Y, Lu D, Tang Y, Zhu J and
            Zhuang J.
  TITLE     Association Between TCF21 Gene Polymorphism with the Incidence of
            Paroxysmal Atrial Fibrillation and the Efficacy of Radiofrequency
            Ablation for Patients with Paroxysmal Atrial Fibrillation
  JOURNAL   Int J Gen Med 15, 4975-4983 (2022)
   PUBMED   35601004
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1245)
  AUTHORS   Usui J, Yaguchi M, Yamazaki S, Takahashi-Kobayashi M, Kawamura T,
            Kaneko S, Seshan SV, Ronco P and Yamagata K.
  TITLE     Transcription factor 21 expression in injured podocytes of
            glomerular diseases
  JOURNAL   Sci Rep 10 (1), 11516 (2020)
   PUBMED   32661376
  REMARK    GeneRIF: Transcription factor 21 expression in injured podocytes of
            glomerular diseases.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1245)
  AUTHORS   Yang L, Gao X, Luo H, Huang Q, Su D, Tan X and Lu C.
  TITLE     TCF21 rs12190287 Polymorphisms Are Associated with Ventricular
            Septal Defects in a Chinese Population
  JOURNAL   Genet Test Mol Biomarkers 21 (5), 312-315 (2017)
   PUBMED   28346832
REFERENCE   4  (bases 1 to 1245)
  AUTHORS   Bastami M, Ghaderian SM, Omrani MD, Mirfakhraie R, Vakili H, Parsa
            SA, Nariman-Saleh-Fam Z and Masotti A.
  TITLE     MiRNA-Related Polymorphisms in miR-146a and TCF21 Are Associated
            with Increased Susceptibility to Coronary Artery Disease in an
            Iranian Population
  JOURNAL   Genet Test Mol Biomarkers 20 (5), 241-248 (2016)
   PUBMED   26909569
REFERENCE   5  (bases 1 to 1245)
  AUTHORS   Bhandari RK, Schinke EN, Haque MM, Sadler-Riggleman I and Skinner
            MK.
  TITLE     SRY induced TCF21 genome-wide targets and cascade of bHLH factors
            during Sertoli cell differentiation and male sex determination in
            rats
  JOURNAL   Biol Reprod 87 (6), 131 (2012)
   PUBMED   23034159
  REMARK    GeneRIF: Data suggest that Sry (sex determining region Y) and Tcf21
            induce initial stages of embryonic Sertoli cell differentiation;
            Scx (scleraxis) induces later stages. This
            cascade--Sry>Tcf21>Scx--appears to promote subsequent sex
            differentiation.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1245)
  AUTHORS   Quaggin SE, Schwartz L, Cui S, Igarashi P, Deimling J, Post M and
            Rossant J.
  TITLE     The basic-helix-loop-helix protein pod1 is critically important for
            kidney and lung organogenesis
  JOURNAL   Development 126 (24), 5771-5783 (1999)
   PUBMED   10572052
REFERENCE   7  (bases 1 to 1245)
  AUTHORS   Familari M and Giraud AS.
  TITLE     Identification of the rat homologue of the mouse capsulin gene by
            cDNA representational difference analysis
  JOURNAL   Gene 222 (2), 245-248 (1998)
   PUBMED   9831659
REFERENCE   8  (bases 1 to 1245)
  AUTHORS   Hidai H, Bardales R, Goodwin R, Quertermous T and Quertermous EE.
  TITLE     Cloning of capsulin, a basic helix-loop-helix factor expressed in
            progenitor cells of the pericardium and the coronary arteries
  JOURNAL   Mech Dev 73 (1), 33-43 (1998)
   PUBMED   9545526
REFERENCE   9  (bases 1 to 1245)
  AUTHORS   Lu J, Richardson JA and Olson EN.
  TITLE     Capsulin: a novel bHLH transcription factor expressed in epicardial
            progenitors and mesenchyme of visceral organs
  JOURNAL   Mech Dev 73 (1), 23-32 (1998)
   PUBMED   9545521
REFERENCE   10 (bases 1 to 1245)
  AUTHORS   Quaggin SE, Vanden Heuvel GB and Igarashi P.
  TITLE     Pod-1, a mesoderm-specific basic-helix-loop-helix protein expressed
            in mesenchymal and glomerular epithelial cells in the developing
            kidney
  JOURNAL   Mech Dev 71 (1-2), 37-48 (1998)
   PUBMED   9507058
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC100106.1.
            
            On Sep 2, 2005 this sequence version replaced XM_341737.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC100106.1, EV780087.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1245
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1p12"
     gene            1..1245
                     /gene="Tcf21"
                     /gene_synonym="Capsulin; Msf-1; Pod1"
                     /note="transcription factor 21"
                     /db_xref="GeneID:252856"
                     /db_xref="RGD:620523"
     exon            1..675
                     /gene="Tcf21"
                     /gene_synonym="Capsulin; Msf-1; Pod1"
                     /inference="alignment:Splign:2.1.0"
     CDS             226..765
                     /gene="Tcf21"
                     /gene_synonym="Capsulin; Msf-1; Pod1"
                     /codon_start=1
                     /product="transcription factor 21"
                     /protein_id="NP_001027569.1"
                     /db_xref="GeneID:252856"
                     /db_xref="RGD:620523"
                     /translation="MSTGSLSDVEDLQEVEMLDCDSLKVDSNKEFGTSNESTEEGSNC
                     ENGSPQKGRGGLGKRRKAPTKKSPLSGVSQEGKQVQRNAANARERARMRVLSKAFSRL
                     KTTLPWVPPDTKLSKLDTLRLASSYIAHLRQILANDKYENGYIHPVNLTWPFMVAGKP
                     ESDLKEVVTASRLCGTTAS"
     exon            676..1232
                     /gene="Tcf21"
                     /gene_synonym="Capsulin; Msf-1; Pod1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttaaggcca ggactccagg ggtggggaga taaagctcta gtttccctgt cgcgggaatc
       61 cttttggtcg ttttcacaac tctgtgaagg ggaagctgtg agacaaggct gccagatccc
      121 atctggaaac ccaacacaca gaagtggcaa ctccgtactt tagagaccct ttcatttccg
      181 tttcggtgtc tctctctctc tccctcctcc acctcctctc taaacatgtc cactggctcc
      241 ctcagcgatg tagaagacct tcaagaggtg gagatgctgg actgtgactc cctgaaagtg
      301 gattccaaca aggagtttgg aacttccaat gagagcaccg aggagggttc caactgcgag
      361 aacgggtctc cacagaaggg tcgtggtggc ctgggcaaga ggaggaaggc gcccaccaag
      421 aaaagcccgc tgagcggggt cagccaggag ggcaagcagg tccagcgcaa cgcggccaat
      481 gcacgcgagc gggcccgcat gcgggtgctg agcaaggcct tctccaggct caagactacc
      541 cttccctggg tgcccccgga caccaagctc tccaagctgg acactctcag gctggcgtcc
      601 agctacatcg cgcacctgag gcagatcctg gccaacgaca agtacgagaa tggttacatt
      661 cacccagtca acctgacttg gccctttatg gtggccggca aacctgagag tgacctaaag
      721 gaagtggtga ccgcgagccg cttgtgtgga accaccgcat cctgaccttg gaggtgtgag
      781 tctgggaacc ctgcgctctc gagggcagtg ggccggtgag ggtgacgacc cctgccctcc
      841 cctccccgtc tctgctgccg ccttgcatcg ctcctctccc tatcccaccc cgcaagaaca
      901 cttaactgcg acgaggagat tcgtttccaa accgaaggag accaactgta cttacagatt
      961 cccatctatt taacttgatt aacttctgcc ctgaatgact gtgagcctgg ctggtccaag
     1021 tgcaatatgt aattatatat agtatatata aatagataat aagagcctat caatgtgtat
     1081 cttttgtaca atatgttgta aaatgtagat catagaatag ctgactttga cagtcacatt
     1141 tataaaataa atcactcaaa gaaatatatt tttttcaaac aggttttgct atttccgaaa
     1201 ataaatcttt ctttatattg ctaaaaaaaa aaaaaaaaaa aaaaa
//
