LOCUS       NM_001025735            2390 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus transcription elongation factor A1 (Tcea1), mRNA.
ACCESSION   NM_001025735 XM_342799
VERSION     NM_001025735.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2390)
  AUTHORS   He,Y., Yan,C., Fang,J., Inouye,C., Tjian,R., Ivanov,I. and
            Nogales,E.
  TITLE     Near-atomic resolution visualization of human transcription
            promoter opening
  JOURNAL   Nature 533 (7603), 359-365 (2016)
   PUBMED   27193682
REFERENCE   2  (bases 1 to 2390)
  AUTHORS   Kwak,H. and Lis,J.T.
  TITLE     Control of transcriptional elongation
  JOURNAL   Annu Rev Genet 47, 483-508 (2013)
   PUBMED   24050178
  REMARK    Review article
REFERENCE   3  (bases 1 to 2390)
  AUTHORS   Ito,T., Arimitsu,N., Takeuchi,M., Kawamura,N., Nagata,M., Saso,K.,
            Akimitsu,N., Hamamoto,H., Natori,S., Miyajima,A. and Sekimizu,K.
  TITLE     Transcription elongation factor S-II is required for definitive
            hematopoiesis
  JOURNAL   Mol Cell Biol 26 (8), 3194-3203 (2006)
   PUBMED   16581793
REFERENCE   4  (bases 1 to 2390)
  AUTHORS   Kalogeraki,V.S., Tornaletti,S., Cooper,P.K. and Hanawalt,P.C.
  TITLE     Comparative TFIIS-mediated transcript cleavage by mammalian RNA
            polymerase II arrested at a lesion in different transcription
            systems
  JOURNAL   DNA Repair (Amst) 4 (10), 1075-1087 (2005)
   PUBMED   16046193
REFERENCE   5  (bases 1 to 2390)
  AUTHORS   Tamura,K., Miyata,K., Sugahara,K., Onishi,S., Shuin,T. and Aso,T.
  TITLE     Identification of EloA-BP1, a novel Elongin A binding protein with
            an exonuclease homology domain
  JOURNAL   Biochem Biophys Res Commun 309 (1), 189-195 (2003)
   PUBMED   12943681
REFERENCE   6  (bases 1 to 2390)
  AUTHORS   Saso,K., Ito,T., Natori,S. and Sekimizu,K.
  TITLE     Identification of a novel tissue-specific transcriptional activator
            FESTA as a protein that interacts with the transcription elongation
            factor S-II
  JOURNAL   J Biochem 133 (4), 493-500 (2003)
   PUBMED   12761297
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC099141.1.
            
            On Jul 22, 2005 this sequence version replaced XM_342799.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC099141.1, FQ227501.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2390
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q12"
     gene            1..2390
                     /gene="Tcea1"
                     /note="transcription elongation factor A1"
                     /db_xref="GeneID:362479"
                     /db_xref="RGD:1309880"
     exon            1..146
                     /gene="Tcea1"
                     /inference="alignment:Splign:2.1.0"
     CDS             84..989
                     /gene="Tcea1"
                     /note="transcription elongation factor S-II protein 1;
                     transcription elongation factor A (SII) 1"
                     /codon_start=1
                     /product="transcription elongation factor A protein 1"
                     /protein_id="NP_001020906.1"
                     /db_xref="GeneID:362479"
                     /db_xref="RGD:1309880"
                     /translation="MEDEVVRIAKKMDKMVQKKNAAGALDLLKELKNIPMTLELLQST
                     RIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLDGPSTDKDSEEKKKEPAISSQNSPE
                     AREESSSSSHVSSRKDETNARDTYVSSFPRAPSTSDSVRLKCREMLAAALRTGDDYVA
                     IGADEEELGSQIEEAIYQEIRNTDMKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPD
                     LFARMTAEEMASDELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQV
                     QTRSADEPMTTFVVCNECGNRWKFC"
     exon            147..209
                     /gene="Tcea1"
                     /inference="alignment:Splign:2.1.0"
     exon            210..315
                     /gene="Tcea1"
                     /inference="alignment:Splign:2.1.0"
     exon            316..403
                     /gene="Tcea1"
                     /inference="alignment:Splign:2.1.0"
     exon            404..549
                     /gene="Tcea1"
                     /inference="alignment:Splign:2.1.0"
     exon            550..606
                     /gene="Tcea1"
                     /inference="alignment:Splign:2.1.0"
     exon            607..761
                     /gene="Tcea1"
                     /inference="alignment:Splign:2.1.0"
     exon            762..908
                     /gene="Tcea1"
                     /inference="alignment:Splign:2.1.0"
     exon            909..980
                     /gene="Tcea1"
                     /inference="alignment:Splign:2.1.0"
     exon            981..2358
                     /gene="Tcea1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggcttcggg gctcgtcgag cgtctgcgca gcttctctcg cttcccgtcc gctgtggccg
       61 ggcgagaggg gccttccgga gccatggagg acgaggtggt tcgcattgcc aagaagatgg
      121 acaaaatggt gcagaaaaag aacgcggccg gtgcattgga tttgctgaaa gagcttaaga
      181 atattcccat gaccctggaa ttattacagt ccacgagaat tggaatgtct gtcaatgcta
      241 ttcgcaagca gagtacagat gaagaagtca catctctagc caaatcactc atcaaatcct
      301 ggaaaaaatt actagatgga ccatcaactg ataaagactc tgaagaaaag aaaaaagaac
      361 ctgcaatttc atcacagaat agccctgaag caagagaaga aagtagttct agcagccatg
      421 taagcagcag aaaggatgag acaaatgctc gagatactta tgtttcatct tttcctcggg
      481 caccaagcac ttctgattct gtgcggctca agtgtaggga gatgcttgcc gcagctctcc
      541 ggacaggaga tgattatgtt gctattggag ctgatgagga agaactggga tctcagattg
      601 aggaagctat atatcaagaa ataaggaata cagacatgaa atacaaaaac agagtacgaa
      661 gtaggatatc aaatcttaaa gatgcaaaga atccaaattt aaggaaaaat gtgctgtgtg
      721 ggaatattcc tcctgacctg tttgctagaa tgacagcaga ggaaatggct agtgatgagc
      781 tcaaagagat gaggaaaaac ctgaccaaag aagccatcag ggagcatcag atggccaaga
      841 ccggtgggac ccagactgac ttgttcactt gtggcaaatg taaaaagaag aactgcactt
      901 acacacaggt gcaaactcgt agtgctgatg aaccaatgac aacttttgtt gtatgtaatg
      961 aatgtggaaa tcggtggaag ttctgttgag tttggaagaa ttggcaaggt atctggacca
     1021 ttaagaaaaa ccaattttgt aattagcttt aaaattaagc caggctactc gtttccctgc
     1081 aagtgaaatt cgtaaacagt atacatccca tgggttggtc tttgttgttt acctgacagt
     1141 ctttcttaaa tgccttctgt ggtctcagat cagctgggag accataaaat aattatataa
     1201 tgtgttgctt tgttcttctt ttttataagt tgatgttgca ttttattaaa tattaacttt
     1261 ttatagtcta gaacacaaaa attctgttga tcttacatac agataaattg cttttctcat
     1321 tggtatgtac ctaaaaatat taaaggaaaa ggaataatat aaattttaga gttaccaact
     1381 atactatgtt ttctagtagt acttgaccgg cttctcaaag ttgtgcacac aattggaact
     1441 cgcatattac tttactctta attactgtgt tcacaagcct cggatcctta gatctcttgc
     1501 gtctatgact aaccacagtg accacttctt gtatttctca cacatgtata ttaccatttt
     1561 ttaatagatt ttactttgaa aactgacttg gttgccatca gtttatttta tttgattttg
     1621 tgatgtattt tagttttaca gagctaagct tttcacaaag cccctcacag gcatacttct
     1681 ggtgaatttt cccccatagg aagccatgct gtgaagaaaa tattagtatc tgagtagagt
     1741 tcctggaggc aacatgactg tacttgcact tggaaaccta ctgaccaagg attaagcctg
     1801 agaactatgt aaattactaa gctgtgctct ttgcatatgg aggatgcgaa aaaaatcctt
     1861 tagactgaat cttttgtgct aaattttttc ttacatgatg atgtcaagcc aactgaaatg
     1921 taggccgtag caagtagttt tacaaaacat acttcacaat taagttttac ttttgtttaa
     1981 atgtgtccca cttgttttgc tagtactaag cagtggcttt cacatcgttt tcttgacaca
     2041 gacgtcctat tgcacagagc aaaggccact atttaaagtt tacaacttaa gtgcctctgc
     2101 ctgtgttcag acttctgtgt aaagaccact gcacaagctt tgcgctctgc tctgctctgc
     2161 tctgctctgc agaccgtttg acataacata gaaaacaata tgctaaaagg attggtccat
     2221 gggtaattgc tgtcacttta aaaataaagt acattttgaa agaattagtt taaaagtaat
     2281 aaggttaaaa tagccccact tttaagtgat ccattttaaa atttgtaaat caataaaatt
     2341 ttttgttgtt aaatataaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
