LOCUS       NM_001399348            5261 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus TRPM8 channel-associated factor 1 (Tcaf1),
            transcript variant 1, mRNA.
ACCESSION   NM_001399348 XM_342675
VERSION     NM_001399348.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5261)
  AUTHORS   Gkika,D., Lemonnier,L., Shapovalov,G., Gordienko,D., Poux,C.,
            Bernardini,M., Bokhobza,A., Bidaux,G., Degerny,C., Verreman,K.,
            Guarmit,B., Benahmed,M., de Launoit,Y., Bindels,R.J., Fiorio Pla,A.
            and Prevarskaya,N.
  TITLE     TRP channel-associated factors are a novel protein family that
            regulates TRPM8 trafficking and activity
  JOURNAL   J Cell Biol 208 (1), 89-107 (2015)
   PUBMED   25559186
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Jan 6, 2022 this sequence version replaced XM_342675.8.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360176.2103738.1,
                                           SRR26643298.22744.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-145               JAXUCZ010000004.1  72613267-72613411   c
            146-779             JAXUCZ010000004.1  72606745-72607378   c
            780-1774            JAXUCZ010000004.1  72599761-72600755   c
            1775-1872           JAXUCZ010000004.1  72599410-72599507   c
            1873-2086           JAXUCZ010000004.1  72598669-72598882   c
            2087-2326           JAXUCZ010000004.1  72598123-72598362   c
            2327-2664           JAXUCZ010000004.1  72596536-72596873   c
            2665-2962           JAXUCZ010000004.1  72594744-72595041   c
            2963-5261           JAXUCZ010000004.1  72589710-72592008   c
FEATURES             Location/Qualifiers
     source          1..5261
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q24"
     gene            1..5261
                     /gene="Tcaf1"
                     /gene_synonym="Fam115a; RGD1565474"
                     /note="TRPM8 channel-associated factor 1"
                     /db_xref="GeneID:362353"
                     /db_xref="RGD:1565474"
     exon            1..145
                     /gene="Tcaf1"
                     /gene_synonym="Fam115a; RGD1565474"
                     /inference="alignment:Splign:2.1.0"
     exon            146..779
                     /gene="Tcaf1"
                     /gene_synonym="Fam115a; RGD1565474"
                     /inference="alignment:Splign:2.1.0"
     CDS             160..2922
                     /gene="Tcaf1"
                     /gene_synonym="Fam115a; RGD1565474"
                     /note="family with sequence similarity 115, member A"
                     /codon_start=1
                     /product="TRPM8 channel-associated factor 1"
                     /protein_id="NP_001386277.1"
                     /db_xref="GeneID:362353"
                     /db_xref="RGD:1565474"
                     /translation="MATPSATFEALMNGVTSWDIPDDSVPCELLLIGEASFPIMVNDV
                     GQVLIAASSYGRGRMVVASHEDFLVESQLFVFLVNAVGWLRSSSESTIGVHSSLAPLV
                     KILESCGIESKIEPEVNDSLGVYCIDAYNETMTDKLLQFVKRGGGLLIGGQAWDWDNL
                     GEDDRVLFSFPGNLVTSVAGVYFTDNKADTNCYKVSKKMPKIPILVRCEDDLSEDRDE
                     LLHGISDLDITNSDCFPSQLLVHGSLAFPLGLDTHHGCVIAAARYGRGRVVVTGHKVL
                     FTVGKLGPFLLNAVRWLDGGRRGKIVVQTELRTLSGLLAVGGIDTSIEPQLTSDASVY
                     CFEPTSDVGVKELQEFVAEGGGLFVGTQAWWWAFKNPGVSPLARFPGNLLLNAFGISI
                     TSQSLNPGPFHIPKAGTRTYHFRSTLAEFQVIMGRKRGNVEKGWLAKLGPDGAAFLQI
                     PAEEIPAYMSVHRLLRKLLSRYRLPVATRENPVINDCCRGAMLSLATGLAHSGSDLSL
                     LIPEIEDVYSSCYLRPSESPITVDVNCTNPGTRYCWMSTGLYIPGRQVIDVSLPEDAA
                     SADLKIQIGCHTDDLTRASKLFRGPLVINRCCLDKPMKSINCLWGGLLYIIVPQNSKL
                     GTVPLTVKGAVRAPFYKLGETSKEEWKRRLLEYPGPWGELATDNLILTVPTANLRTLE
                     NPEPLLRLWDEVMQAVAKLGGEPFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQE
                     LISEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRSRA
                     NIALWPPVREKRVRMYLSKGPNVKNWNAWTALETYLQLQEAFGWEPFIRLFTEYRNQT
                     TNSPTDNVNKMNLWVKMFSQQVQKNLAPFFEAWAWPIQKEVATSLAYLPEWKENIMKL
                     YLLTQL"
     exon            780..1774
                     /gene="Tcaf1"
                     /gene_synonym="Fam115a; RGD1565474"
                     /inference="alignment:Splign:2.1.0"
     exon            1775..1872
                     /gene="Tcaf1"
                     /gene_synonym="Fam115a; RGD1565474"
                     /inference="alignment:Splign:2.1.0"
     exon            1873..2086
                     /gene="Tcaf1"
                     /gene_synonym="Fam115a; RGD1565474"
                     /inference="alignment:Splign:2.1.0"
     exon            2087..2326
                     /gene="Tcaf1"
                     /gene_synonym="Fam115a; RGD1565474"
                     /inference="alignment:Splign:2.1.0"
     exon            2327..2664
                     /gene="Tcaf1"
                     /gene_synonym="Fam115a; RGD1565474"
                     /inference="alignment:Splign:2.1.0"
     exon            2665..2962
                     /gene="Tcaf1"
                     /gene_synonym="Fam115a; RGD1565474"
                     /inference="alignment:Splign:2.1.0"
     exon            2963..5261
                     /gene="Tcaf1"
                     /gene_synonym="Fam115a; RGD1565474"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaacccctcc tctcctcccg ctcggatctc ctccccgtta agctccaagc tttcggtggc
       61 tgctcggggg cgccttggtg ctccacagag aagcccctgt tcagccctcc tggtgcggtc
      121 ctagaagcgc caagacagct gcctggaacc aacagaacca tggcaactcc atctgctacc
      181 tttgaggcgc ttatgaatgg agtaacaagt tgggatatcc ctgatgattc cgttccatgt
      241 gaactgcttc ttattggaga ggcttctttt cctataatgg tgaatgatgt aggccaggtc
      301 ctcattgctg cctcttccta tggcagaggt cgcatggtgg tagcatctca tgaggacttc
      361 ttggtggaaa gccagctctt tgtctttctt gtcaatgctg ttggatggct tcgttcctct
      421 tctgagtcaa ccattggtgt gcactcatct ttagcaccat tggtgaaaat cctcgagagc
      481 tgtggaatag agtcaaagat tgaaccagaa gtgaatgact ctctgggggt ttactgcatc
      541 gatgcctaca atgaaaccat gacggataag ctactccagt ttgtgaaacg tggcgggggc
      601 ttgctcatag gaggccaagc ctgggattgg gataacctgg gtgaagatga tagagtactg
      661 ttctcctttc ctgggaatct ggtgaccagt gtggctggtg tgtacttcac tgacaacaaa
      721 gcggacacga attgctataa agtctccaag aagatgccta agatacccat cttagttcgt
      781 tgtgaagatg acctctcaga agacagagat gagcttctac atggcatctc agacctggat
      841 atcaccaact cggactgctt cccatcccag ctactagtgc atgggtcttt ggcttttcct
      901 ttggggctag atacccacca tggctgtgtg atagctgctg cccgctatgg ccggggacgg
      961 gtggttgtaa ctggtcataa ggtattattc actgtgggta aactcggccc ctttctgctc
     1021 aatgctgtcc gctggctaga tggcggccgc agaggcaaga ttgtggtaca gaccgagctg
     1081 agaacactaa gtggtctgct tgcagtaggg ggtatagaca ccagcattga gccccaactg
     1141 accagtgacg caagtgtcta ttgcttcgaa cccacaagtg atgtgggagt taaggaacta
     1201 caggagtttg tagctgaggg tggtgggctg tttgttggaa cccaagcctg gtggtgggct
     1261 tttaagaacc caggagtgtc cccactggct cgattcccag gaaacctgct cctcaatgcc
     1321 tttggtatca gcatcacaag ccaaagcctc aatccaggac ctttccatat cccaaaagca
     1381 ggaacaagga cctatcactt ccgctctacc ctggcagagt tccaggtgat aatgggcagg
     1441 aaaagaggaa atgtggagaa gggctggcta gccaagctgg gcccagatgg ggcagctttc
     1501 ctgcagattc ctgcagagga gatccctgct tacatgtccg tgcacagact cctgcggaag
     1561 ctgctgagtc gctaccggct tccagtggca accagagaga acccggtcat caatgactgt
     1621 tgtagggggg ccatgctttc cctggccaca ggtctggccc actctggaag tgacctctca
     1681 ctgctaatcc cagaaattga agatgtgtac agcagctgct acctacgccc ctcagagtct
     1741 cccatcaccg tggatgtcaa ctgcaccaat ccaggcaccc gatactgctg gatgagcact
     1801 ggactctaca tacctggaag gcaagtcata gatgtttcct tgcctgaaga tgctgcctct
     1861 gctgatctga agatacaaat tggctgtcac actgatgacc tgaccagggc cagcaagctc
     1921 ttccgaggcc cccttgtgat taaccggtgt tgcttggata aacccatgaa atcaatcaac
     1981 tgcctctggg gtggtctcct ctatatcatt gtgcctcaga atagcaaact gggtactgtg
     2041 cccctcacag tgaagggagc cgttcgtgcc ccattctaca agctagggga gacatccaag
     2101 gaagagtgga agaggcgtct cctggaatat ccaggtccgt ggggagaact ggccactgac
     2161 aacctcatct tgactgtgcc tactgcaaat cttcgaactc tggagaaccc tgagccactg
     2221 ctccgcctct gggatgaggt gatgcaggct gtggctaagt tgggaggcga gcccttccct
     2281 ttgcggctgc cacagaggat agtggctgat gttcagatct cagtaggctg gatgcatgca
     2341 gggtacccca tcatgtgcca tctggagtca gtgcaggagc tcattagtga gaagctcatc
     2401 cggaccaagg gactgtgggg tcctgtgcat gagctgggcc gcaaccagca gaggcaggag
     2461 tgggagttcc ccccacatac tacggaagcc acatgcaacc tgtggtgtgt ttatgtgcat
     2521 gaaacagttc tgggcatacc tcgaagccgt gccaacattg cgctatggcc ccctgttcgg
     2581 gagaagagag tccgaatgta tttaagcaag ggacccaatg tgaaaaactg gaatgcctgg
     2641 actgcgttgg aaacgtacct acagcttcaa gaggcctttg gttgggagcc atttattcgt
     2701 ctcttcactg agtacagaaa ccagacaacg aactcgccca cagacaacgt caacaaaatg
     2761 aatctctggg tcaagatgtt ctcccagcaa gtgcagaaga atctggctcc gttctttgag
     2821 gcctgggcct ggcctatcca gaaagaagtg gctacaagct tagcctatct gcctgaatgg
     2881 aaagaaaata taatgaaatt gtatcttctc acacagttgt aaggagtgcc catcgaggtg
     2941 gcagatagag aggtttgggg aggcctcact gaaactgaag tccaagaata cagtccagga
     3001 aaactgagac ctctcagcaa aggaaactaa aagcatttgg ttggagaaga tctcaacaaa
     3061 tttctggaag agagaaagta aatgaagaga aataatgagt gggaaacatg gccgcccatt
     3121 tcagacagaa tacactgatc cgaacactgg aaccccaaag agacttgagc acttctagct
     3181 actaaataat tgtaccagtt gtaaattaac ccccgttcta ctcagcccta actcttgtac
     3241 atagaacaca gaaaacctac cattgatact agtgaaactg ttattgttat tgttgtttga
     3301 ataaagaaat caaataaacc acctgaggag aggtaaagaa ttagtgctcc aaatgatact
     3361 cttttcatgg aacaatgtgc cccactagcc tgtcaggtaa ttttcttctc agagttggga
     3421 ctcttactca catgcctaaa gcttctaggc atagcagaga tttgctggac aaacaggagt
     3481 catttaacag acgatagtta acagaggttc tcaatgtgga ttttctgata caaatattca
     3541 tacatagaag ggaccaagga agaagcatat gggaaataaa cacttagaca taaaagggtt
     3601 gaaaaaatat aaactaaaag aaatacaatt tatacagaaa aaaatctgta agattctgac
     3661 cctctctcca gagagacttg agatgcattt gttaaaaata tatactaaga gaaaatcctg
     3721 aacattttaa gagcaaaact agactgacat aaatattcag cagataggct ggaaaacaaa
     3781 atagaaagaa tcctcccaga ggcgcaacaa caaacaatag gaaagaagga aaggggaaca
     3841 gacaaccact gtttaactgt tgggagtttc cagaagacgg gacagagaga atgtggacaa
     3901 taaaacaata agaaacagtt gacgagcacc agtttgaggg gaccagtact gaccacatct
     3961 aggcacagtc ctaaataaaa ttggaacaat agggttagaa ggaacatgtt ggaagtgccc
     4021 agggaaggaa aaccaactga agtaaatctt agaatagtct ggcaacttca gtagcagtgc
     4081 tgaatgctag aagtcaagga accaatgatt gacttttgaa aacttttgtt cccagaactc
     4141 catatagtac agaatgtcaa gagtaatgca aaaagaaaaa cgtttttggg caagtgagtc
     4201 tttagaaact ctccctcctt cctttgtacc cttattacag aagttttcca tttaaaagaa
     4261 aatatatgtg tgtgtgtata catgtgtgtg tgtatacatg tgtgtgtgtg tgtgtgtgtg
     4321 tgtgtgtgta agtccaaaga ataagaggaa agaagagagc actactctga gctttgtgaa
     4381 gaatgtgcca gagtagccct gagaaaatag gacatttgga gataatggaa ggcatagagc
     4441 ctttaatcac aaatattaaa caaatgtcaa gaaattgtgg ctgaaccatg aatagaatgg
     4501 gataggatgt caaactctca tgaagtatga gaaaagactt gactgggcac tggtggtagg
     4561 tatgtttcct ttcccttata cgggcatcat ggcattggga gtgtagagaa aataaatttc
     4621 ttccacttgg cttgataaag gtattttaat attccaagta atatagatgc cacttatgga
     4681 tggtcaaagt tttgattagc ttattaacaa agcctaaaag atttaatgtt acacccagaa
     4741 tagagctgga aagggatgtt gaccagatga tgcagaaaat gaaggctgaa ttagttgaga
     4801 gaagagaagt agaagaaaaa tggggctact taaatattca aagtggggat gaaaagatgc
     4861 tgccttcaga taatggaaca cagttgcatg gttagtttgc tggtccatgc tataaatcag
     4921 accctcaaaa gaatatctac caagcatttg gacaagggta ggcaggggaa aggtgaaggt
     4981 ggtgtatgtt atatccttat cttttgtaat ggtgaaagat taaaaattgt ctaaagttaa
     5041 taagtcaaga aattattgtt caaacatgtt gtttaaaagt aggaagttag ccaccagaag
     5101 atccaaaaat agatattatt aaaagcatct aggaaatgag actagagaaa gagggtgggt
     5161 gggaaaccat ttttatttca agttcctctg tactatttaa atttttttac cttgtgcatg
     5221 tattatttgg gaaagttttt aataaactca aataaaacat c
//
