LOCUS       NM_001025152            2545 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus tandem C2 domains, nuclear (Tc2n), mRNA.
ACCESSION   NM_001025152 XM_576089
VERSION     NM_001025152.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2545)
  AUTHORS   Antoni,G., Oudot-Mellakh,T., Dimitromanolakis,A., Germain,M.,
            Cohen,W., Wells,P., Lathrop,M., Gagnon,F., Morange,P.E. and
            Tregouet,D.A.
  TITLE     Combined analysis of three genome-wide association studies on vWF
            and FVIII plasma levels
  JOURNAL   BMC Med Genet 12, 102 (2011)
   PUBMED   21810271
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2545)
  AUTHORS   Fukuda,M. and Mikoshiba,K.
  TITLE     Tac2-N, an atypical C-type tandem C2 protein localized in the
            nucleus
  JOURNAL   FEBS Lett 503 (2-3), 217-218 (2001)
   PUBMED   11526914
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC088432.1.
            
            On Jul 1, 2005 this sequence version replaced XM_576089.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088432.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5756307,
                                           SAMEA5760383 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2545
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q32"
     gene            1..2545
                     /gene="Tc2n"
                     /gene_synonym="Mtac2d1; Tac2-N"
                     /note="tandem C2 domains, nuclear"
                     /db_xref="GeneID:500707"
                     /db_xref="RGD:1563876"
     exon            1..82
                     /gene="Tc2n"
                     /gene_synonym="Mtac2d1; Tac2-N"
                     /inference="alignment:Splign:2.1.0"
     exon            83..215
                     /gene="Tc2n"
                     /gene_synonym="Mtac2d1; Tac2-N"
                     /inference="alignment:Splign:2.1.0"
     exon            216..246
                     /gene="Tc2n"
                     /gene_synonym="Mtac2d1; Tac2-N"
                     /inference="alignment:Splign:2.1.0"
     exon            247..359
                     /gene="Tc2n"
                     /gene_synonym="Mtac2d1; Tac2-N"
                     /inference="alignment:Splign:2.1.0"
     CDS             293..1762
                     /gene="Tc2n"
                     /gene_synonym="Mtac2d1; Tac2-N"
                     /note="membrane targeting (tandem) C2 domain containing 1"
                     /codon_start=1
                     /product="tandem C2 domains nuclear protein"
                     /protein_id="NP_001020323.1"
                     /db_xref="GeneID:500707"
                     /db_xref="RGD:1563876"
                     /translation="MAAEFIKSCCRGCFYGETEKHKFSVEKEFKASASNSQNTIGITQ
                     LTSVLAKPQVGCNEDYLLSKLPCDGKEVQFVVPRFKLSYIQPRTQGTPSHLDELEGSA
                     RASFGDQKTELCSSFYHGSIYDVYNPCYMYQHFSPDLSRRFLPHCETKTLYGSVCDLR
                     TSKLPGSPGLSKSMLDLTTSSQRFIQRHDSFSSVPSSSSSRKNSQGSNRSLDTITLSG
                     DERDLGRLNVKLFYNSSAEQIWITILQCRDISWPSSYGDTPTISIKGILTLSKPIHFK
                     SSAKEGSNAIDFMETFVFAIKLQNLQAVRLAFKIQTQTPKKKTIGECSLSLRTLSTQE
                     MDYSLEIIPPSKFSVCQAELELGTCFQAVNSRIQLQILEAQYLPSSSTPLALSFFVKV
                     GMFSSGELIYKKKTRLLKASSGRVKWGETMIFPLIQTEKEIVFLIKLYSRSSVRRKHF
                     VGQLWISEDSNNVEAVNQWKETVTNPEKVVIKWHKLNPS"
     exon            360..590
                     /gene="Tc2n"
                     /gene_synonym="Mtac2d1; Tac2-N"
                     /inference="alignment:Splign:2.1.0"
     exon            591..758
                     /gene="Tc2n"
                     /gene_synonym="Mtac2d1; Tac2-N"
                     /inference="alignment:Splign:2.1.0"
     exon            759..850
                     /gene="Tc2n"
                     /gene_synonym="Mtac2d1; Tac2-N"
                     /inference="alignment:Splign:2.1.0"
     exon            851..926
                     /gene="Tc2n"
                     /gene_synonym="Mtac2d1; Tac2-N"
                     /inference="alignment:Splign:2.1.0"
     exon            927..1027
                     /gene="Tc2n"
                     /gene_synonym="Mtac2d1; Tac2-N"
                     /inference="alignment:Splign:2.1.0"
     exon            1028..1144
                     /gene="Tc2n"
                     /gene_synonym="Mtac2d1; Tac2-N"
                     /inference="alignment:Splign:2.1.0"
     exon            1145..1336
                     /gene="Tc2n"
                     /gene_synonym="Mtac2d1; Tac2-N"
                     /inference="alignment:Splign:2.1.0"
     exon            1337..1451
                     /gene="Tc2n"
                     /gene_synonym="Mtac2d1; Tac2-N"
                     /inference="alignment:Splign:2.1.0"
     exon            1452..1651
                     /gene="Tc2n"
                     /gene_synonym="Mtac2d1; Tac2-N"
                     /inference="alignment:Splign:2.1.0"
     exon            1652..2517
                     /gene="Tc2n"
                     /gene_synonym="Mtac2d1; Tac2-N"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgcctccta ggcggtgggt gcagcgaggg tgcccgcgcc tcaggggccg tgagtgagga
       61 gcgcgagacc tcggcgacgc agcttctagc aaccacttat ttatcttgtg tctctggatt
      121 tgcctacgaa cagaatcatg taatctgatc tccatgtttt acttctttta cctaacatac
      181 tgtgtccaag gtttctccac gatagaacat gagagaggat caaatcttgg actttgcaca
      241 ttctaggttg atatcaaaat tggaaatttt ctagttatta gaaatcgaaa gtatggcagc
      301 agaatttata aagagttgtt gtagaggatg tttctatggt gaaacggaaa agcacaagtt
      361 ttctgtggaa aaagagttta aagcatcagc ctcaaatagc caaaacacca tcggtataac
      421 tcaattgact tctgttttag caaagcccca agttggctgt aatgaggatt acttgctttc
      481 caaattacca tgtgatggta aagaagtaca atttgtggtg cccaggttta aattatctta
      541 tattcagcct aggacacaag gaactccttc acatctggat gaactggaag gatctgccag
      601 agcatctttt ggagatcaaa agacagaact ttgtagttca ttctaccatg gatccatcta
      661 tgatgtgtat aatccatgct atatgtatca acacttttca cctgatttaa gtaggcgctt
      721 tcttcctcat tgtgaaacga aaacgttata tggatctgtt tgtgatttaa ggaccagtaa
      781 acttcctggt tctcctgggc taagcaaatc tatgctagat cttacaactt catctcagcg
      841 attcatccag agacatgact cattttccag tgtgcctagt agttcttctt caagaaaaaa
      901 ttctcagggc agtaacagaa gcctggatac aattaccctg tcaggagatg aacgagactt
      961 ggggagattg aatgtgaaat tgttttataa ttcttcagca gagcagattt ggatcacaat
     1021 tttgcagtgc agagatataa gttggccctc tagttatgga gatactccta caatttctat
     1081 aaaaggaatt ttaacattat ccaaaccaat acatttcaaa tcttcagcca aagaaggttc
     1141 caatgctatt gactttatgg aaacgtttgt atttgctatc aaactacaaa atctacaagc
     1201 tgtgagactt gcatttaaga ttcaaactca aactcccaag aagaaaacca ttggagaatg
     1261 ttctctttca ctcagaactc ttagtaccca ggaaatggat tactcattgg aaataatacc
     1321 accttcaaaa ttttctgttt gccaagcaga acttgaactg gggacttgtt ttcaagcagt
     1381 aaatagcagg attcagctgc aaatcctcga ggcacaatac cttccaagtt catcaacacc
     1441 tctggctttg agtttttttg tgaaggtagg gatgtttagc tcaggagagc tgatttataa
     1501 gaagaagaca cgcttactga aggcctccag tggaagagta aaatggggag aaactatgat
     1561 ttttccactc atacagactg aaaaagaaat tgttttcctt attaaacttt acagtcggag
     1621 ctctgtaaga agaaaacatt ttgtaggcca gctctggata agtgaagaca gtaataacgt
     1681 tgaagcagtg aaccaatgga aagagacagt tacaaatcca gaaaaggttg ttatcaagtg
     1741 gcacaagtta aatccatctt gaaaacttcg gacattaatt tagtgaagag acagcttgat
     1801 gatcttttag aagaaacaaa tttctaaaac ttgcaatgag ttttaccagg tatacaaagt
     1861 gaatgaaatg ttttaaaatg gtgccaaaat atgataaaat aaaagggtaa tagtagtagg
     1921 tcaatgtaat ggattataaa atctataaaa atatgaatca tagatagata tttctatatt
     1981 tgttttgctt ttgtttttaa gatactcaaa tcacatcagt ctagacatca gtctttttaa
     2041 aagtactatt agatatttac aagactttac tacttttcca gtgctagaca tgattaatta
     2101 gatttggtta cactgtttat atctttatat gtattcttct cacatcaaaa atgaatagaa
     2161 acatcccatt aattttttcc tatatttgag gaaaattgat agccttactt ctttttatct
     2221 gtaaactatt gcatggtcat tttataagct gcttatttcc tggagaatta gagaattatc
     2281 tagatttttt aaagagtaaa caaagcttgg agctagcagg attgcctggt gcgtaaagga
     2341 gcttgtcagc acactgacaa tttgagttcc atccctgtaa tgcaacatga tggaaggaaa
     2401 gaaccaattt gtccatattg ttcactgtca ttaacatgta tgccatcaca cacacaaaat
     2461 aaataaataa ataacttaaa agagattaaa taaaggtaaa ctgaagatca aaatataaaa
     2521 aaaaaaaaaa aaaaaaaaaa aaaaa
//
