LOCUS       NM_001012154            2153 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus transforming growth factor beta regulator 4
            (Tbrg4), mRNA.
ACCESSION   NM_001012154 XM_341253
VERSION     NM_001012154.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2153)
  AUTHORS   Boehm,E., Zaganelli,S., Maundrell,K., Jourdain,A.A., Thore,S. and
            Martinou,J.C.
  TITLE     FASTKD1 and FASTKD4 have opposite effects on expression of specific
            mitochondrial RNAs, depending upon their endonuclease-like RAP
            domain
  JOURNAL   Nucleic Acids Res 45 (10), 6135-6146 (2017)
   PUBMED   28335001
REFERENCE   2  (bases 1 to 2153)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   3  (bases 1 to 2153)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   4  (bases 1 to 2153)
  AUTHORS   Simarro,M., Gimenez-Cassina,A., Kedersha,N., Lazaro,J.B.,
            Adelmant,G.O., Marto,J.A., Rhee,K., Tisdale,S., Danial,N.,
            Benarafa,C., Orduna,A. and Anderson,P.
  TITLE     Fast kinase domain-containing protein 3 is a mitochondrial protein
            essential for cellular respiration
  JOURNAL   Biochem Biophys Res Commun 401 (3), 440-446 (2010)
   PUBMED   20869947
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC087073.1.
            
            On Feb 11, 2005 this sequence version replaced XM_341253.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC087073.1, FQ217643.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2153
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14q21"
     gene            1..2153
                     /gene="Tbrg4"
                     /note="transforming growth factor beta regulator 4"
                     /db_xref="GeneID:360977"
                     /db_xref="RGD:1309737"
     exon            1..453
                     /gene="Tbrg4"
                     /inference="alignment:Splign:2.1.0"
     CDS             49..1938
                     /gene="Tbrg4"
                     /note="protein TBRG4; transforming growth factor beta
                     regulated gene 4"
                     /codon_start=1
                     /product="FAST kinase domain-containing protein 4"
                     /protein_id="NP_001012154.1"
                     /db_xref="GeneID:360977"
                     /db_xref="RGD:1309737"
                     /translation="MAVRLMKQCTCLLREATRLVPTVAPVGRLRLAGVACKTLTSSVS
                     SPSSGSLTELLGKEQVFTPYPEHQEVDYLIEKATRPEELLELLGGDHSLHHNHAALIL
                     IRLSYLLSEKPKEKALLVEDARFQQLVRLVDSQITSVWHGTLVKLLRSLYTLVLPQGS
                     KELRSVEQEVRWRLRRLKYKHLVFLAESCAPFMKEQHSKELLAELLRHLERRWTEISD
                     SRTLVSMMTMAGHLSESLMNRLEDKCLELVEQFGPDELRKVLMTLAAQSRRSVPLLRA
                     ISYHLVQKPFPMTKGMLLDLAYAYGKLSFHQTQVAQRLAADLLPFIPSMTPGEVARCA
                     KSFAFLKWLNLPLFEAFTQHLLNSAQDVSLSHLCSVLLAFARLNFHPEQEDQFFNLVH
                     EKLDSVLGSLEPALQVDLVWALCVLQQVQVAELQTVLHPGLHTRFLESKSPKDQSTFQ
                     KLVHINSTALLEYPEYKGPFLPASAVAPSPSPSNKKMTPLQKELQDALKALLGNNDTG
                     SLEVATQYGWVLDAEVLLDAEGHFLPLRDFVAPHLAQPVGNQPLPPGAKRIAFLRWEF
                     PNFNSRSKDLLGRFVLARRHVLAAGFLVVDVPYYEWLDLKSEWQKTAYLKDKMRKAVA
                     EELAK"
     exon            454..777
                     /gene="Tbrg4"
                     /inference="alignment:Splign:2.1.0"
     exon            778..949
                     /gene="Tbrg4"
                     /inference="alignment:Splign:2.1.0"
     exon            950..1107
                     /gene="Tbrg4"
                     /inference="alignment:Splign:2.1.0"
     exon            1108..1218
                     /gene="Tbrg4"
                     /inference="alignment:Splign:2.1.0"
     exon            1219..1363
                     /gene="Tbrg4"
                     /inference="alignment:Splign:2.1.0"
     exon            1364..1609
                     /gene="Tbrg4"
                     /inference="alignment:Splign:2.1.0"
     exon            1610..1721
                     /gene="Tbrg4"
                     /inference="alignment:Splign:2.1.0"
     exon            1722..1836
                     /gene="Tbrg4"
                     /inference="alignment:Splign:2.1.0"
     exon            1837..2128
                     /gene="Tbrg4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acttactagg agtcttaacc tccctccctc ttccctgtgc ccaccatcat ggcagttcgc
       61 ctgatgaagc agtgcacatg cctacttaga gaagccaccc gcctagttcc taccgttgct
      121 ccagttggcc gactgagact tgctggggtg gcctgtaaga ctttgacttc ctccgtcagt
      181 tccccctctt caggttcctt gacggagttg ttgggaaaag agcaggtgtt tactccctac
      241 ccagagcacc aagaggtgga ctacctcatt gagaaagcca ccaggccaga ggagctgctg
      301 gaactgctag gtggtgatca tagtctgcac cacaatcatg cagccctcat tctcatccgg
      361 ctgtcctacc tgctgtctga gaagccaaag gaaaaggcct tgcttgtaga ggatgctcgc
      421 tttcagcaac ttgtcaggct agttgacagt cagataactt ctgtctggca tgggaccctc
      481 gtgaagctgc tgcgaagtct gtacacacta gtgcttcctc agggctccaa ggagctgcgg
      541 tccgtggaac aggaagtacg ctggcgtctg cggaggctaa agtataagca cttggtcttc
      601 ctggctgagt cctgtgcccc cttcatgaaa gagcagcact caaaggagct gctggctgag
      661 ctgctaaggc acctggagag gcgctggaca gagatcagcg acagccgcac attggtgtcc
      721 atgatgacca tggcagggca cttgtcagag tcactgatga accgcttgga agacaagtgc
      781 ctggagctgg tggagcagtt tggccctgat gagctgcgga aggtgctaat gacgctggca
      841 gcccagagcc ggcggtcggt gcccttgctg cgggccattt cctaccacct ggtacagaag
      901 cccttcccca tgacgaaagg catgctcctg gacctggcct acgcctatgg taagctcagt
      961 ttccaccaaa cccaagtggc ccagcgcctc gctgctgacc tcctgccctt cattcccagc
     1021 atgacgcctg gagaggtggc ccgctgcgcc aagtcctttg ccttcctcaa gtggctcaac
     1081 ctgcctttgt ttgaagcctt tactcagcac ctcctgaaca gcgctcagga tgtctccctg
     1141 tcccatctgt gcagcgttct tcttgccttt gcccggctga actttcatcc tgaacaagag
     1201 gatcagtttt tcaacttggt gcatgagaag ctggactccg tgctggggag cctggagcca
     1261 gccctgcagg tggacctggt gtgggccctg tgtgtgctac agcaagtgca ggtagcagag
     1321 ctgcaaacag ttctccatcc tgggctccac acacgctttc tagagagcaa gtctccaaag
     1381 gaccagagta ccttccagaa attggtccac atcaacagca ctgccctgct ggagtaccct
     1441 gaatataaag gccctttcct gccagcctca gctgtagccc ccagtccctc accctccaac
     1501 aagaagatga cacccctaca gaaggagctg caagacgcac tgaaggcact gctggggaac
     1561 aatgacacag gcagcctgga ggtggccaca cagtatggct gggtgctgga tgcagaggtg
     1621 ctgctggatg ctgagggcca cttcctgccc ctgagagatt ttgttgctcc tcaccttgcc
     1681 cagccagttg ggaaccagcc actacccccg ggagctaaaa gaatcgcttt cctacgctgg
     1741 gagttcccca acttcaacag cagaagcaag gacttgttgg ggcgttttgt cctggcccgt
     1801 cgacatgtgc tggctgcagg cttcctagtg gtggatgtcc catattatga gtggctggat
     1861 ttgaagtctg aatggcagaa aaccgcctac ctcaaggaca agatgcgaaa agcagtggct
     1921 gaggagctgg ccaagtgacc tttcccatct gttcagactg catctcaaga cctgagggct
     1981 cagggaccca gacccagcag tgagtgctgg gccggccaga gttgtcaccc atcagcgaga
     2041 tgaactctct gtaggacctt ggccacagta gggggtgctc agcagctccc agggcaggcg
     2101 gtcctaataa atcacttgtt ttggtggaaa aaaaaaaaaa aaaaaaaaaa aaa
//
