LOCUS       NP_001009344             406 aa            linear   ROD 02-JUN-2024
DEFINITION  transforming growth factor beta regulator 1 [Rattus norvegicus].
ACCESSION   NP_001009344 XP_006226427 XP_217108
VERSION     NP_001009344.2
DBSOURCE    REFSEQ: accession NM_001009344.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 406)
  AUTHORS   Tompkins,V.S., Hagen,J., Frazier,A.A., Lushnikova,T.,
            Fitzgerald,M.P., di Tommaso,A., Ladeveze,V., Domann,F.E.,
            Eischen,C.M. and Quelle,D.E.
  TITLE     A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains
            chromosomal stability
  JOURNAL   J Biol Chem 282 (2), 1322-1333 (2007)
   PUBMED   17110379
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CO572447.1, BC087142.1 and BI285514.1.
            
            On or before Dec 15, 2013 this sequence version replaced
            XP_006226427.1, NP_001009344.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC087142.1, FQ219023.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Rattus norvegicus"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q22"
     Protein         1..406
                     /product="transforming growth factor beta regulator 1"
                     /note="transforming growth factor beta regulated gene 1"
                     /calculated_mol_wt=44654
     Region          1..26
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5PQK8.2)"
     Site            2
                     /site_type="acetylation"
                     /note="N-acetylserine.
                     /evidence=ECO:0000250|UniProtKB:Q3YBR2; propagated from
                     UniProtKB/Swiss-Prot (Q5PQK8.2)"
     Site            13
                     /site_type="phosphorylation"
                     /note="Phosphothreonine.
                     /evidence=ECO:0000250|UniProtKB:Q3UB74; propagated from
                     UniProtKB/Swiss-Prot (Q5PQK8.2)"
     Region          116..144
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5PQK8.2)"
     Region          183..233
                     /region_name="FYRN"
                     /note="F/Y-rich N-terminus; pfam05964"
                     /db_xref="CDD:461787"
     Region          239..320
                     /region_name="FYRC"
                     /note="F/Y rich C-terminus; pfam05965"
                     /db_xref="CDD:461788"
     CDS             1..406
                     /gene="Tbrg1"
                     /coded_by="NM_001009344.2:86..1306"
                     /db_xref="GeneID:300521"
                     /db_xref="RGD:1305123"
ORIGIN      
        1 msvlsglase prtplsskar mkrlpkknqn ekyrlkylrl rraakatvfe naavcdeiar
       61 leekflkake erryllkkll qihaltegep qaaapshsss lplaygvtss vgtiqgagps
      121 tgaeepfakk skkekkekgk ensklevlkk tskrkkmegg arklvrpial dpsgqpvfpi
      181 glggltvysl geiitnrpgf hdenaiypvg ycstrvyasm kcpdqkclyt cqikdggvqp
      241 qfeivpeddp rntivgssad acyeellrai saatgklmpn plscgadffg fshptihnli
      301 qscpeaqncv nyqwvkfdac kprkgqlsqe lpendaamsl eafptqtfdd dhedsilpgs
      361 ldlpelqhea fvssyqpefl theplvdtdl qhlkspsqcs piqssd
//
