LOCUS       NM_001004198            1923 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus TATA box binding protein (Tbp), mRNA.
ACCESSION   NM_001004198 XM_217785
VERSION     NM_001004198.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1923)
  AUTHORS   Sanguesa,G., Shaligram,S., Akther,F., Roglans,N., Laguna,J.C.,
            Rahimian,R. and Alegret,M.
  TITLE     Type of supplemented simple sugar, not merely calorie intake,
            determines adverse effects on metabolism and aortic function in
            female rats
  JOURNAL   Am J Physiol Heart Circ Physiol 312 (2), H289-H304 (2017)
   PUBMED   27923787
REFERENCE   2  (bases 1 to 1923)
  AUTHORS   Wang,Y., Shan,Q., Meng,Y., Pan,J. and Yi,S.
  TITLE     Mrpl10 and Tbp Are Suitable Reference Genes for Peripheral Nerve
            Crush Injury
  JOURNAL   Int J Mol Sci 18 (2), 263 (2017)
   PUBMED   28134789
  REMARK    GeneRIF: Mrpl10 and Tbp might be used as suitable reference genes
            for sciatic nerve stump and dorsal root ganglions, respectively.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1923)
  AUTHORS   He,Y., Yan,C., Fang,J., Inouye,C., Tjian,R., Ivanov,I. and
            Nogales,E.
  TITLE     Near-atomic resolution visualization of human transcription
            promoter opening
  JOURNAL   Nature 533 (7603), 359-365 (2016)
   PUBMED   27193682
REFERENCE   4  (bases 1 to 1923)
  AUTHORS   Louder,R.K., He,Y., Lopez-Blanco,J.R., Fang,J., Chacon,P. and
            Nogales,E.
  TITLE     Structure of promoter-bound TFIID and model of human pre-initiation
            complex assembly
  JOURNAL   Nature 531 (7596), 604-609 (2016)
   PUBMED   27007846
  REMARK    Erratum:[Nature. 2016 Aug 4;536(7614):112. doi:
            10.1038/nature17984. PMID: 27096372]
REFERENCE   5  (bases 1 to 1923)
  AUTHORS   Gouge,J., Satia,K., Guthertz,N., Widya,M., Thompson,A.J.,
            Cousin,P., Dergai,O., Hernandez,N. and Vannini,A.
  TITLE     Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2
  JOURNAL   Cell 163 (6), 1375-1387 (2015)
   PUBMED   26638071
REFERENCE   6  (bases 1 to 1923)
  AUTHORS   Ozer,J., Bolden,A.H. and Lieberman,P.M.
  TITLE     Transcription factor IIA mutations show activator-specific defects
            and reveal a IIA function distinct from stimulation of TBP-DNA
            binding
  JOURNAL   J Biol Chem 271 (19), 11182-11190 (1996)
   PUBMED   8626665
REFERENCE   7  (bases 1 to 1923)
  AUTHORS   DeJong,J., Bernstein,R. and Roeder,R.G.
  TITLE     Human general transcription factor TFIIA: characterization of a
            cDNA encoding the small subunit and requirement for basal and
            activated transcription
  JOURNAL   Proc Natl Acad Sci U S A 92 (8), 3313-3317 (1995)
   PUBMED   7724559
REFERENCE   8  (bases 1 to 1923)
  AUTHORS   Mengus,G., May,M., Jacq,X., Staub,A., Tora,L., Chambon,P. and
            Davidson,I.
  TITLE     Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28:
            three subunits of the human transcription factor TFIID
  JOURNAL   EMBO J 14 (7), 1520-1531 (1995)
   PUBMED   7729427
REFERENCE   9  (bases 1 to 1923)
  AUTHORS   Igarashi,A., Makino,Y., Tamura,T. and Nohara,H.
  TITLE     Isolation of rat TATA factor as an active 75kDa protein complex
  JOURNAL   Biochem Biophys Res Commun 204 (3), 1125-1130 (1994)
   PUBMED   7980586
REFERENCE   10 (bases 1 to 1923)
  AUTHORS   Ou,S.H., Garcia-Martinez,L.F., Paulssen,E.J. and Gaynor,R.B.
  TITLE     Role of flanking E box motifs in human immunodeficiency virus type
            1 TATA element function
  JOURNAL   J Virol 68 (11), 7188-7199 (1994)
   PUBMED   7933101
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC081939.1.
            
            On Sep 10, 2004 this sequence version replaced XM_217785.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC081939.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132275, SAMD00132295
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1923
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q12"
     gene            1..1923
                     /gene="Tbp"
                     /gene_synonym="TFIID"
                     /note="TATA box binding protein"
                     /db_xref="GeneID:117526"
                     /db_xref="RGD:67398"
     exon            1..158
                     /gene="Tbp"
                     /gene_synonym="TFIID"
                     /inference="alignment:Splign:2.1.0"
     exon            159..319
                     /gene="Tbp"
                     /gene_synonym="TFIID"
                     /inference="alignment:Splign:2.1.0"
     CDS             266..1222
                     /gene="Tbp"
                     /gene_synonym="TFIID"
                     /codon_start=1
                     /product="TATA-box-binding protein"
                     /protein_id="NP_001004198.1"
                     /db_xref="GeneID:117526"
                     /db_xref="RGD:67398"
                     /translation="MDQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPVQ
                     NTNSLSILEEQQRQQQQQQQQQQQQQQQAVATAAASVQQSTSQQPTQGASGQTPQLFH
                     SQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDLK
                     TIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYAR
                     VVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIK
                     PRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKTT"
     exon            320..699
                     /gene="Tbp"
                     /gene_synonym="TFIID"
                     /inference="alignment:Splign:2.1.0"
     exon            700..787
                     /gene="Tbp"
                     /gene_synonym="TFIID"
                     /inference="alignment:Splign:2.1.0"
     exon            788..879
                     /gene="Tbp"
                     /gene_synonym="TFIID"
                     /inference="alignment:Splign:2.1.0"
     exon            880..1047
                     /gene="Tbp"
                     /gene_synonym="TFIID"
                     /inference="alignment:Splign:2.1.0"
     exon            1048..1142
                     /gene="Tbp"
                     /gene_synonym="TFIID"
                     /inference="alignment:Splign:2.1.0"
     exon            1143..1868
                     /gene="Tbp"
                     /gene_synonym="TFIID"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctctggacca ccgcctcggc ggggtcatga aatccagtgc caagtgtgag cctctccaag
       61 gggctggcac cggacagctc ggcgcaccgt acatctcagc tgcttccccc ggtggaagac
      121 agttttaccc aggcctgcgg ctgctcgttt tgtccccaca tcactgtttc atggtgcgtg
      181 acgataaccc agaaagtcga agacgtttct aaggagataa gaggatgctc taggaaaaat
      241 ctgagtaccg aagaaagtga gagtcatgga ccagaacaac agccttccac cttatgctca
      301 gggcttggcc tccccacagg gtgccatgac tcctggaatt cccatcttca gtccaatgat
      361 gccttacggc acagggctta ctccacagcc tgttcagaac accaatagtt tatctatttt
      421 ggaagagcaa caaagacagc agcagcagca gcagcagcag caacagcagc agcaacagca
      481 ggcagtagca actgcagcag cctcagtaca gcaatcaaca tctcagcagc ccacacaggg
      541 tgcctcaggc cagaccccac aactcttcca ttctcaaact ctaaccacag caccattgcc
      601 aggcaccacc cccttgtatc cttcaccaat gactcctatg acccctatca ctcctgccac
      661 accagcctct gagagctctg ggattgtacc acagctccaa aatattgtat ccaccgtgaa
      721 tcttggctgt aaacttgacc taaagaccat tgcacttcgt gccagaaatg ctgaatataa
      781 tcccaagcgg tttgctgcag tcatcatgag aataagagag ccacgaacaa ctgcgttgat
      841 cttcagttct gggaaaatgg tgtgcacagg agccaagagt gaagaacaat ccagactagc
      901 agcaagaaaa tacgctagag ttgtgcagaa gctgggcttc ccagctaagt tcttagactt
      961 caagatccag aacatggtgg ggagctgtga tgtgaagttc cccataaggc tggaaggcct
     1021 tgtgttgacc caccagcagt tcagtagcta tgagccagaa ttatttcctg gattaatcta
     1081 cagaatgatc aaacccagaa ttgttctcct tatttttgtt tctggaaaag ttgtattaac
     1141 aggtgctaaa gttagagcag agatttatga agcatttgaa aacatctacc ccatcttaaa
     1201 gggattcagg aagaccacat agttgtctgc catggactcc tgtctcccct acccacgtgt
     1261 tttttttttt aaaaccagtc agttttggta ccactgaagg tacagttgtg aggacactca
     1321 gttacaggtg gcagcatgaa gtgacactgt gtgtcctact gcaggatact agaaaggttc
     1381 cctcctctgc actgagatca ccctgcagca tcactgtgag ttgcttgctc tgtgctgcta
     1441 cttgggcggc actgcccatt tatttatatt tagattgtaa acactgctgc tggtgattgt
     1501 tggtttaagg gacagaactt ttaagtgttc aagccacctg tacaattgga ctttttattt
     1561 taacctttcc cacacaagca agtttttata tttctaccag aaaagtaaaa atctttttta
     1621 aaagtgttgt ttttctagtt tgtaactctt aggagttctt tttgtgccag atacattccg
     1681 ccttcccagt attgcaggac tgaatagtgg tattcatcaa aacaaatgac tgtacatact
     1741 tttctttcct gagtactctg cacaaaagtg cagctgtaaa ttgttagatt tttgttataa
     1801 atgatacctt gtaagtcatg tgatcatact gtcaaagaaa tttattttag atataatgcc
     1861 tgagaccaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1921 aaa
//
