LOCUS       XM_039093968            6551 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus TBC1 domain family, member 4 (Tbc1d4),
            transcript variant X1, mRNA.
ACCESSION   XM_039093968
VERSION     XM_039093968.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051350.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Jan 16, 2024 this sequence was replaced by
            NM_001427219.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6551
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6551
                     /gene="Tbc1d4"
                     /note="TBC1 domain family, member 4; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 39 ESTs, 3 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     7 samples with support for all annotated introns"
                     /db_xref="GeneID:306117"
                     /db_xref="RGD:1561609"
     CDS             586..4488
                     /gene="Tbc1d4"
                     /codon_start=1
                     /product="TBC1 domain family member 4 isoform X1"
                     /protein_id="XP_038949896.1"
                     /db_xref="GeneID:306117"
                     /db_xref="RGD:1561609"
                     /translation="MESPSCIQDEPFPHPLEPEPIALAQPGATKPGDKRFRLWYVGGS
                     CLDRRTTLPMLPWLMAEIRRRSLKPEAGGCGAPAAREVLLVLSAPFLRCVPAPGVGVG
                     GGAGSGAVQPNTGVFIFEHKAQHISRFIHNSHDLTYFAYLIKAQPDDPESQMACHVFR
                     ATDPNQVPDVISSIRQLSKAAMKEDAKPSKDNEDAFYNSQKFEVLYCGRVIVTHKKAP
                     SSLIDDCKDKFSLHEQQRLKLQGERGGDPGDGDEMGVLEAESPVSPDDGLPEKPDGLV
                     NCPRALPSLASLPALASQPALASSRVCFPERILEDCGFDEQQEFRSRCSSVTGVMQKK
                     VHENNQKTQPRRRHASAPSHVQPSDSEKNRTMLFQVGRFEINLISPDTKSVVLEKNFK
                     DISSCSQGIKHVDHFGFICRESLEPGLSQYICYVFQCANESLVDEVMLTLKQAFSTAA
                     ALQSAKTQIKLCEACPMHSLHKLCERIEGLYPPRAKLVIQRHLSSLTDNEQADIFERV
                     QKMKPISDQEENELVILHLRQLCEAKQKTHVHIGEGQAIISNSTIPENSTSGGRFKLD
                     VLKNKAKRSLTSSLENIFSRGANRMRGRLGSVDSFERSNSLASEKDFSPGGSPPGTPP
                     ASPLSSAWHTFPEEDSDSPQFRRRAHTFSHPPSSSRRKLNLQDGKAHGLRSPLLRQNS
                     SEQCSVLPSARRMCKESNSSSSLPSLHTSFSAPSFTASSFLKSFYQSSGRLSPQYENE
                     ISDGEGRKRTSSTCSNESLSAGGTPVTPRRISWRQRIFLRVASPVNKSPSAMQQQKDG
                     LDRTELLPLSPLSPTMEEEPLVIFLSGDEDTEKVEEKKKSKEIKSLWKKAIHQQILLL
                     RMEKENQKLEARRDELQSRKVKLDYEEVGTCQKEVLIAWDKKLLNCRTKIRCDMEDIH
                     TSLKEGVPKSRRGEIWQFLALQYRLRHRLPNKHQPPDTSYKELLKQLTAQQHAILVDL
                     GRTFPTQPYFSVQLGAGQLSLFNLLKAYSLLDKEVGYCQGISFVAGVLLLHMSEEQAF
                     EMLKFLMYDLGFRKQYRPDMMSLQIQMYQLSRLLHDYHRDLYNHLEENEISPSLYAAP
                     WFLTLFASQFPLGFVARVFDIIFLQGTEVIFKVALSLLSSQEALVMECENFENIVEFL
                     KSTLPDMNTTEMEKIITQVFEMDISKQLHAYEVEYHVLQDELLESSYACEDNESLEKL
                     ERANNQLKRQNMDLLEKLQVAHAKIQALESNLETLLTRETKMKALIRTLEQDKMAYQK
                     TVEQIRKLLPADALANCELLLKDLSYPTNDKAKAGNKP"
ORIGIN      
        1 gtcggcgggt gcaggagccg cccgcgcgag gccacgtttg tttttgttat tttccattgg
       61 agtagttctc cgagactgag cgggccgtgc gggcaccccc gaccttccag gtgacagccg
      121 gtcaccctgc taggagtcag ctccgccccg agtcgcccct tcccgcccac agcttcactc
      181 tccgcccagc cttccagtgc cagcccaggg cgagcgcgcc ggccgcagcg ggctgcagga
      241 gtaggagcag gagcaggagc aggagctgga gcaggagacc gcggctgccc tggtccctga
      301 ccccgaggac ggacgggcgg cgggaggaca gaccggcccc gggacgcgat ttccaggaag
      361 gaggatgcgc gcgtgagcct gtgtctcccg ctagtctact gagctgcagc cagaggctct
      421 gagccgtgcc cggggaagtg tcgcatgggg cagggccgct gaagcacgga ctttaaaggc
      481 tggtggcacc gagtcaggcg cgggggcctg ggacgacagt tagcagtttc ctccgctcct
      541 gcacagtgag agttgggggc gcggtgccct cgctaggcgc gagttatgga gtcgcctagc
      601 tgcattcagg atgagccttt cccgcacccc ctagagccgg agccgattgc cctagcgcag
      661 ccaggtgcca ccaagcctgg cgacaagcgc ttccggctat ggtacgtggg agggtcttgc
      721 ttggatcgca ggaccacgct gcctatgctc ccgtggctca tggccgagat ccgtcggcgc
      781 agcctgaagc ccgaggcggg cggctgcggg gcgcccgcgg cccgggaggt gctcctggtg
      841 ctcagcgccc ccttcctgcg ttgcgtcccc gcgccaggtg tcggggtcgg cgggggcgca
      901 ggctccggag ccgtacagcc caacaccggg gtgttcatct tcgagcacaa ggctcagcac
      961 atctcgcgct tcatccacaa cagccacgac ctcacctact ttgcctattt gatcaaggcg
     1021 cagcccgacg accccgagtc acagatggcc tgccacgttt tccgtgccac ggaccctaac
     1081 caggttccag atgtgatcag tagcatccgg caattatcca aggctgccat gaaggaggac
     1141 gccaaaccca gcaaagataa tgaggacgcc ttctacaact ctcagaagtt cgaagtgctc
     1201 tattgtgggc gggtgatcgt gacccacaag aaggcacctt ccagcctcat tgatgactgc
     1261 aaggacaagt tcagcctgca tgagcagcag cgactgaagt tgcagggcga gagaggtggt
     1321 gaccccgggg acggggacga gatgggtgtc cttgaggctg agtctcctgt gtctccagat
     1381 gacggcctgc ctgagaagcc agatggtcta gtcaactgcc cccgtgctct gccctccctg
     1441 gctagcctcc ctgcgttggc cagccaaccc gcactggcca gctctcgggt ttgtttccca
     1501 gagaggattt tggaagactg tggctttgat gagcagcagg agttccgatc tcggtgcagc
     1561 agtgtcacag gcgtcatgca aaagaaggtt cacgagaaca accagaaaac ccagccaaga
     1621 aggcggcacg caagcgcacc cagtcacgtg cagccctcag actcggagaa gaaccgcacc
     1681 atgctcttcc aggtcggccg ctttgagatt aacctcatca gtccagacac taagtcagtc
     1741 gtgctcgaga agaatttcaa agacatctcc tcttgctctc aggggataaa gcatgtggat
     1801 cactttggct tcatctgccg ggagtctctg gagccggggc tcagccagta catctgttat
     1861 gtgttccagt gtgccaacga atctctggtg gatgaggtca tgctgactct gaagcaagct
     1921 ttcagcacgg ccgctgcact gcagagcgcc aagacgcaga tcaagctgtg tgaggcctgc
     1981 cccatgcact ctttgcataa gctctgtgag agaatcgaag gtctctaccc gcctcgagcc
     2041 aagctggtaa tccagaggca tctctcttca ctgacggata atgagcaagc tgacatcttt
     2101 gaacgggttc agaaaatgaa gcccattagc gaccaggagg agaatgaact tgtgattctg
     2161 cacctgaggc agctttgtga agccaagcag aagacccacg tgcacatcgg ggaaggccag
     2221 gcgattattt caaatagtac aatcccagaa aattcgacaa gcggtgggag gttcaagctt
     2281 gatgttctga aaaacaaagc gaagaggtcc ttaacttcct ccttggaaaa tatcttctcc
     2341 aggggagcta acagaatgag agggcggctc ggaagtgtgg acagcttcga acggtccaac
     2401 agtcttgctt cagagaagga cttttcacca gggggctctc ctcctgggac accgccagcc
     2461 tctccactgt cctccgcctg gcacaccttt cccgaggagg attctgactc gccgcagttt
     2521 cgaagacggg ctcacacgtt cagccaccca ccttcaagtt caaggaggaa gctgaacttg
     2581 caagatggga aggcccacgg actgcggtcc cctctactga ggcagaactc cagtgagcaa
     2641 tgcagtgttc tcccgtcagc ccggcgcatg tgcaaggaga gtaattcttc ctccagcctt
     2701 ccaagccttc acacctcctt ctctgcccct tccttcactg cttcctcttt cctgaaaagc
     2761 ttttaccaga gttcaggtag actgtcccca cagtatgaaa atgaaatcag tgatggagaa
     2821 gggaggaaga ggacctcatc cacctgcagc aacgagtccc taagcgctgg aggaacccct
     2881 gtcactcctc gcagaatttc gtggaggcag cggattttcc tccgggtggc atctcctgtg
     2941 aacaagtccc cctcagctat gcagcagcag aaagatgggc tagaccggac tgagctgctc
     3001 ccgttgtctc ctctctctcc caccatggag gaagagcctc tcgttatatt cttgtctggt
     3061 gacgaggaca cagaaaaagt tgaagagaaa aagaaatcga aggagataaa gagtctgtgg
     3121 aagaaagcta tacaccagca aatcctgttg cttcgaatgg agaaggaaaa ccagaaactg
     3181 gaagcgagaa gagatgaact ccagtctagg aaagttaagt tagactatga agaagttggt
     3241 acgtgtcaga aggaggtctt gatagcatgg gataagaagt tgttaaattg cagaactaag
     3301 atcagatgcg atatggaaga tatccacacg tcccttaaag aaggggtccc taaaagtcgg
     3361 cgaggggaaa tttggcaatt tctagcttta caataccgcc tgagacacag attgcccaac
     3421 aaacaccagc ctccggacac ctcctataag gaacttctga agcagctcac ggctcagcaa
     3481 cacgccatcc tcgtggattt ggggaggact tttcccactc agccttactt ttcagtgcag
     3541 ctcggggcag ggcagctgtc cctcttcaac ctgctgaagg cctactctct gttggacaag
     3601 gaggtaggct actgtcaggg gatcagcttc gtggccggcg tcctgcttct gcacatgagt
     3661 gaggagcaag cctttgaaat gctcaagttc ctcatgtacg acctgggctt ccgcaagcag
     3721 taccgaccgg atatgatgtc actgcagatt caaatgtacc agctgtccag actccttcat
     3781 gactaccacc gggatctcta caatcatctt gaggaaaatg agatcagccc cagtctgtat
     3841 gctgcaccct ggttcctcac actctttgcc tctcagtttc ccttaggatt tgtagccaga
     3901 gtttttgata ttatttttct tcaaggaact gaagttatat ttaaggttgc tctcagttta
     3961 ctgagcagcc aagaggcact ggtaatggag tgtgaaaact ttgaaaacat tgttgaattt
     4021 ctcaaaagta cattacccga tatgaacacc actgaaatgg aaaaaattat tacccaggtt
     4081 tttgagatgg atatttctaa acagttacat gcctatgagg tagaatatca cgtgctgcag
     4141 gatgagcttc tggaatcttc ctatgcctgt gaggataatg agtctctgga gaagctggag
     4201 agagcgaata accaattgaa aagacagaac atggacctct tagaaaaact ccaggtggct
     4261 cacgctaaaa ttcaggcctt ggaatccaac ctagaaactc ttttgaccag agaaaccaaa
     4321 atgaaggctt taatccggac cctggaacaa gataaaatgg cttatcaaaa gacagtggaa
     4381 caaatccgga agctgctacc agcagatgca ctggctaact gtgaattgct gttgaaagac
     4441 ctaagttacc caaccaacga taaagccaag gcgggaaata agccatagtt tcagacagag
     4501 cctccacaga tgacggcttc cttaaaatac ccggaaaaag gaccctgtgt aaaatcgacc
     4561 agaaagctgg taggacagct actactggtg ctgaggtcat cagtaggcga cgtagctctc
     4621 ctcagagcac tctactctta agccatcaca gacacccaga ctgtattttc ttctggttgt
     4681 tgccaactat gtacataacc atatataagt ggacataaag attcatgctt tcaaatcaaa
     4741 cagtaggtgt atattcagag caattttttc tttttttttt ttcagccaga acttcatgaa
     4801 attcacctcc aagggggagt tcaagtaagc ttctccttgg atacacacga aatccttttt
     4861 ctagtgaaac aaatctagaa catctttgta tattgaaata tacttgaaaa aaaaatgaat
     4921 gtattccccc gccccccaaa gactagcatg cttcactcag tgtggtagac agacacattt
     4981 ctttagctct gtgtctgtgt ctataaggga catgatgggc tgccagtctc ccttctgagt
     5041 cttcgaggaa ggtggggctc ttctgccctg cctgctgtgt gacagccttc gagcatcttg
     5101 agtgcggtta ggctatgctt tagatacatg tagggagaaa gcaggacatt gtggctgagt
     5161 caacccacct caaggtgaag aggaatgttg ctaattttct agcagattag accagcattg
     5221 atattcaaac tgaaaatact aggcctcaaa agacaccatt aagctcctgg atagcttttt
     5281 gcctttttat ttaagggact tctatagtgg caaacagttg cttggtgctg tatttaccaa
     5341 gtgagagggt ttgctttttt ttttctcaca aaattatggg agcattctag gtagttctcg
     5401 agaccttcgg ttttagaaga gggaaataaa attaggattt cccaaagatg atatatacca
     5461 cgttcagttg cttttctatc ttttgctcaa tgatagaaca cattttttaa atctctttac
     5521 cctttcatgt gaaaaattta gaactgtgaa atatttagga acaaaccatg gaaagcacac
     5581 tggagtggaa gggaatgtct ccaacccagg taaagcttac ggctctgtgt ttggactccg
     5641 gacttctgct gcgcacccat aggttaccag agaatgtaat tttcccagga catgttgagt
     5701 ccctacagca gagacgatgg attttacaat agtgcctccg aacacagaca cagcagggtt
     5761 ttctttgcct ttccaagcag tgtttaccgt cgctgctctt tcagcccttg tctttttgca
     5821 gatgggttac ttgggggtaa ttttcctcag agagagttta ttgcacacaa gatgaagttt
     5881 tattacaggg cttataggag tcaaggtgta aagtctccaa agacatcgaa gagtggatgc
     5941 cgagcatcta ggctgttccc cgctcgaatg tcagaggtct cacagggtca gaggatcctt
     6001 ggatctaggg ggtgtttctc cgaaaaaaaa aaacaaagtc ttattagcta ggagaggtga
     6061 tgtacacatt ctagattcta ggaagtgctc attatcgatt ctccattcgg ttgagggcca
     6121 ttagttgatc tgtcgcttgg atcttctgga aatgtcttca tttgtagcat cctttattct
     6181 cctaccagga tgaagaggag ttcagcgttt ctgtctgatg gttgtgattg ccttgtgggt
     6241 gtgatacatg ggtggtggtt gagggatcct tatgttgggg aaggaactat tttctttcca
     6301 tttcttcatt aaaagttgac tatgttccgg atgttggggg tccgcagtat gggttgttta
     6361 tggtattcag tgattaagac catgtggata tggtattttt ttttcttttg tgaaaatgat
     6421 ttttctttct ctttggtgat ttaaaaaaat ttgttacacc tgtttcgctt tgtaacttta
     6481 catcttcatc accttcatgt aacgtctagg atcatttcca ataaatatgt tgctgccgtt
     6541 tcctgagctt t
//
