LOCUS       NM_001413794            5944 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus TBC1 domain family, member 2B (Tbc1d2b), mRNA.
ACCESSION   NM_001413794 XM_006243528
VERSION     NM_001413794.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5944)
  AUTHORS   Yoshimura,S., Egerer,J., Fuchs,E., Haas,A.K. and Barr,F.A.
  TITLE     Functional dissection of Rab GTPases involved in primary cilium
            formation
  JOURNAL   J Cell Biol 178 (3), 363-369 (2007)
   PUBMED   17646400
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Nov 9, 2022 this sequence version replaced XM_006243528.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR22582419.1690723.1,
                                           SRR26643292.34942.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN12840106,
                                           SAMN12840107 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-425               JAXUCZ010000008.1  99694213-99694637   c
            426-579             JAXUCZ010000008.1  99675437-99675590   c
            580-748             JAXUCZ010000008.1  99666290-99666458   c
            749-912             JAXUCZ010000008.1  99654108-99654271   c
            913-1151            JAXUCZ010000008.1  99652229-99652467   c
            1152-1535           JAXUCZ010000008.1  99650350-99650733   c
            1536-1646           JAXUCZ010000008.1  99646250-99646360   c
            1647-1840           JAXUCZ010000008.1  99645104-99645297   c
            1841-2335           JAXUCZ010000008.1  99641876-99642370   c
            2336-2453           JAXUCZ010000008.1  99638768-99638885   c
            2454-2639           JAXUCZ010000008.1  99632876-99633061   c
            2640-2761           JAXUCZ010000008.1  99631178-99631299   c
            2762-5944           JAXUCZ010000008.1  99626019-99629201   c
FEATURES             Location/Qualifiers
     source          1..5944
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q31"
     gene            1..5944
                     /gene="Tbc1d2b"
                     /gene_synonym="RGD1307436"
                     /note="TBC1 domain family, member 2B"
                     /db_xref="GeneID:315880"
                     /db_xref="RGD:1307436"
     exon            1..425
                     /gene="Tbc1d2b"
                     /gene_synonym="RGD1307436"
                     /inference="alignment:Splign:2.1.0"
     CDS             66..2957
                     /gene="Tbc1d2b"
                     /gene_synonym="RGD1307436"
                     /codon_start=1
                     /product="TBC1 domain family member 2B"
                     /protein_id="NP_001400723.1"
                     /db_xref="GeneID:315880"
                     /db_xref="RGD:1307436"
                     /translation="MPGAGAGAEESCSGGEGVVPGTGSEAGAVAGREPSRLCGYLQKL
                     SGKGPLRGYRSRWFVFDSRRCYLYYFKSPQDALPLGHLDIADACFSYQGRDEAAEPGA
                     DPPTHFQVHSAGVVTVLKAPNRELMTYWLQELQQKRWEYCNSLDMVKWDSRTSPTPGD
                     FPKGLVARDNTDIISQHPNPSAEKARTVLAVEAAPGELVGDRAAHHPAPGHPNSINFY
                     SLKQWGNEIKNSMSSFRPGRGHSESRRTVFYTNEEWELLDPPPKDLEESLAQEDRKKP
                     VPEGSKGVTSSGFPFEFGRNPYKGKRPLKDIIGSYKNRHSSSDPLIEGTSSGSSGGLA
                     KPVPEMQLQIQSQQEELEQLKKDLSSQKELVQLLQQTVRSSQYDKYFMSHQISQGVPR
                     DTLELLHQKDEQILGLSGQLERFGLEKESLQQEVRTLKSKVGELNERLGMLMETIQAK
                     DEVIIKLSECEGSVSSPTMGPSSPLATPASRDQLELDRLKDSLQGYKSQNKFLNKEIL
                     ELSALRRNAERRERDLMAKYSSLEAKLCQVESKYLILLQEMKTPVCSEEQGPARDVIA
                     QLLEDALQVESQEQPEQAFVKPHLVSEFDIYGFRTVPDDDEEEKLVAKVRALDLKTLY
                     LTENQEVSTGVKWENYFASTMNREMVCSPELKNLIRAGIPHEHRSKVWKWCVDRHTRK
                     FKDSMEPGYFQALLQKALEKQNPASKQIELDLLRTLPNNKHYSSPTSEGIQKLRNVLL
                     AFSWRNPDIGYCQGLNRLVAVALLYLEQEDAFWCLVTIVEVFMPRDYYTKTLLGSQVD
                     QRVFRDLLSEKLPRLHTHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEG
                     PKVIFRFALALFKYKEEEILKLQDSMSIFKYLRYFTRTILDARKLTSISFGDLNPFPL
                     RQIRNRRAYHLEKVRLELTELEAIREDFLRERDTSPDKGELVSDEEEDT"
     exon            426..579
                     /gene="Tbc1d2b"
                     /gene_synonym="RGD1307436"
                     /inference="alignment:Splign:2.1.0"
     exon            580..748
                     /gene="Tbc1d2b"
                     /gene_synonym="RGD1307436"
                     /inference="alignment:Splign:2.1.0"
     exon            749..912
                     /gene="Tbc1d2b"
                     /gene_synonym="RGD1307436"
                     /inference="alignment:Splign:2.1.0"
     exon            913..1151
                     /gene="Tbc1d2b"
                     /gene_synonym="RGD1307436"
                     /inference="alignment:Splign:2.1.0"
     exon            1152..1535
                     /gene="Tbc1d2b"
                     /gene_synonym="RGD1307436"
                     /inference="alignment:Splign:2.1.0"
     exon            1536..1646
                     /gene="Tbc1d2b"
                     /gene_synonym="RGD1307436"
                     /inference="alignment:Splign:2.1.0"
     exon            1647..1840
                     /gene="Tbc1d2b"
                     /gene_synonym="RGD1307436"
                     /inference="alignment:Splign:2.1.0"
     exon            1841..2335
                     /gene="Tbc1d2b"
                     /gene_synonym="RGD1307436"
                     /inference="alignment:Splign:2.1.0"
     exon            2336..2453
                     /gene="Tbc1d2b"
                     /gene_synonym="RGD1307436"
                     /inference="alignment:Splign:2.1.0"
     exon            2454..2639
                     /gene="Tbc1d2b"
                     /gene_synonym="RGD1307436"
                     /inference="alignment:Splign:2.1.0"
     exon            2640..2761
                     /gene="Tbc1d2b"
                     /gene_synonym="RGD1307436"
                     /inference="alignment:Splign:2.1.0"
     exon            2762..5944
                     /gene="Tbc1d2b"
                     /gene_synonym="RGD1307436"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggcgctgcg gcggcggccc ggaggcgcgg ggcgcgaacg cgggcgcggg cgccggcggc
       61 gggccatgcc aggggccggg gctggcgcgg aggagagctg cagtggtgga gagggagtgg
      121 tgccgggaac aggctcggag gctggagcgg tggcgggacg ggagccctcg cggctgtgcg
      181 gctacttgca gaagctctcg ggtaagggcc cgctgcgcgg ctaccgcagc cgctggttcg
      241 tgtttgactc gcgccgctgc tacctctact acttcaagag cccgcaggac gctctaccgc
      301 tcggccacct agacatcgcc gacgcctgct tcagctacca gggccgcgat gaggctgcgg
      361 agccaggagc cgatccgccc acgcacttcc aggtgcacag cgccggtgtg gtcacggtgc
      421 tcaaggctcc taatcgggag ctcatgactt actggctaca ggagcttcag cagaaaagat
      481 gggaatactg caacagcctt gacatggtca agtgggacag caggacgtcc ccaacgccag
      541 gggacttccc caagggcctc gtggcccgag ataacacaga tataatttcc cagcacccaa
      601 atccttctgc agaaaaagcc agaactgtgc tcgccgtgga agctgcccct ggagagctgg
      661 tgggggaccg ggctgctcat catccagccc ccgggcaccc gaattccatt aacttttact
      721 ctctgaagca gtggggaaat gagatcaaaa attcaatgtc gtcattccgt cctgggagag
      781 ggcacagtga gagtcgcagg actgtgtttt acaccaatga agagtgggaa cttctagacc
      841 cgcctcctaa ggacctggag gagtccctcg cacaggaaga caggaaaaag ccagtgcctg
      901 aggggagtaa aggagtcact agttcaggat tcccctttga gtttggacgg aatccttaca
      961 aaggaaagcg ccccttgaaa gacataattg ggtcatacaa aaaccgccac agcagtagtg
     1021 accctttgat cgagggaaca tcatcaggca gcagtggggg tctcgctaag ccagtccctg
     1081 aaatgcagct gcagattcaa agccagcagg aggagctgga gcaactcaag aaggacctat
     1141 ccagtcagaa ggagctcgtt caactgctcc aacagacggt ccgatcctca caatatgaca
     1201 agtattttat gagccaccag atcagccagg gggtcccaag ggacacactg gagctcctcc
     1261 accaaaagga cgagcagatc ttgggcctca gcggccagct ggagcggttc ggcctggaga
     1321 aggaaagtct ccagcaggaa gtgaggactc tgaagagcaa ggtgggagag ctcaatgagc
     1381 ggctggggat gctaatggag accatccagg ccaaggacga ggtcatcatc aagctcagcg
     1441 aatgtgaggg cagcgtgtct tcgcccacca tgggacccag ctctcctttg gccaccccag
     1501 ccagccggga ccagctggag ctggacaggc taaaagacag tctacaaggg tacaaaagcc
     1561 aaaataaatt tctaaacaag gaaattttgg aactctcagc tctacgaaga aatgcagaaa
     1621 ggagagagag ggatctgatg gcgaagtact ctagcctgga agccaagctc tgccaggttg
     1681 aaagtaaata cttgatactg ctccaagaaa tgaagacacc agtttgctca gaagaacagg
     1741 gccctgccag ggatgtcata gcccagttgt tggaggacgc tctgcaggtt gagagccaag
     1801 agcagccaga gcaagcgttt gtcaagcctc atctggtcag tgagttcgat atctacgggt
     1861 ttaggactgt ccctgacgat gatgaggaag agaaattggt cgccaaggtc cgagcattgg
     1921 acctgaagac tctgtacctc acagaaaacc aggaagtttc cactggggtc aagtgggaaa
     1981 actattttgc aagcacaatg aacagggaga tggtgtgctc tcctgagctg aaaaacctga
     2041 tccgagcagg cattccccat gagcaccgct ccaaggtgtg gaagtggtgt gttgaccgtc
     2101 acaccaggaa gttcaaggac agcatggagc caggctactt ccaggcctta ctccagaagg
     2161 ctctagagaa acagaacccg gcctccaagc agattgagct ggacctgctt cggactctgc
     2221 ccaataacaa acattactcc agccccacgt cagagggcat acagaagctt cgcaatgtcc
     2281 tgcttgcctt ctcatggagg aatccggata ttggctactg ccaaggccta aacaggttgg
     2341 tggcagtggc gctcctttac ctggaacaag aggatgcttt ctggtgtctc gttaccattg
     2401 tggaagtctt catgcctcga gactattaca caaagactct attaggatcc caggtggacc
     2461 agcgggtgtt cagagacctc ctgagtgaga agctgcctcg actgcacacc cattttgagc
     2521 agtacaaagt ggactacacc ctcatcacct tcaactggtt tctggtggta ttcgtggaca
     2581 gcgttgtcag cgacatcctc tttaagatat gggactcttt cctttatgag ggaccaaagg
     2641 ttattttccg ttttgccctg gcacttttta aatacaagga agaggagatc ctgaagctgc
     2701 aggattcgat gtccattttc aagtatctcc gatacttcac tcgcactatc cttgatgcca
     2761 ggaagctgac cagcatctcc tttggggatc tgaacccctt ccccctgcgc cagatccgga
     2821 accggagagc ctaccacttg gagaaggtcc ggctggagct gacagagctg gaggccattc
     2881 gagaggactt cctgcgtgag cgggacacta gccctgacaa aggcgagctg gttagcgatg
     2941 aggaggaaga cacttgaatg aatccccacc ccaggatgct gccttccttc ttgccttcct
     3001 tcataaccaa aagtagcaaa ggcgcatctg cacatcagct gtcagaatga aacatctaca
     3061 gcctctgggc acctgcgggg cagatgtcca aagctaagct gcactttctc gtctgccatg
     3121 agggcagggg tctgatggct ttacagccat ttccatgccg tggcattcag tcatatgcgt
     3181 catatgcttg ctgcctgatg ggtgagtcac caggcgactg tttccaaggg cctgtttaca
     3241 tcatctgcca gttgtatgtt tcacctacag aaactgtttg acatttccct gtgcgctttc
     3301 tttttatcca agggcaactc tgtggaggag tgcacatgga gctgcagcgt ggctgcatcc
     3361 aggggtaaaa ggtcaccata agaagaggga cctctttaaa aaaaagcgag cacagaactg
     3421 gcctccctag agagcgtggg agccctctgc tggtggcttc gcactgccag ccactatccc
     3481 ttctggacta acctttgccc tcctatacag ccttttcaga ttgtagcact cacgctgctc
     3541 tgcagccagc cccacacttc tcattgccag ctattctgcc agatgtctgt cccagcttac
     3601 agtggggcta gcgcatctgg gaggtgactt atagacaaca ttctccaact gtggctagat
     3661 tggcgttcca aaggaacctt acagtaaccc acccctgcat aaaggaacac aggaaactcc
     3721 tatctgtggc ttgtgggctc ctggatggca gtggccaggg ctctagaatc tcttctgccc
     3781 aacagctggg tggggagtag agctgactgc cagcttccta catctggaag cacctttgct
     3841 tgggaacaag agtaatgagt tctcctagtc tctgtgttgc ctggatcatc cttgtcctta
     3901 acagggatct gaggacactg tggcctctgg tatagcagac tctggggact tggaacactt
     3961 ccttcttgaa gcccagagag ggtctgaaca aaaaaggtta tttttgctca gtcccagagc
     4021 atccctaatg gtggctgtta tgagaaaaca tcttcttaca cagtattatg ggaacacaag
     4081 ggaaacagcc tcaagtggac tactttacac tacctaggga aaagaaatta gaaacaatcc
     4141 ttagtgtaaa cacactcaga ctgaggagtg gagcaagaca gtttcgagaa acgctttttc
     4201 catgacccgt tttcctgttt ttgctgtctg ctttctagca cttgaatggc tgagtccatt
     4261 ttcagcatct aaatttgctt cacttctcta aagttgcttc atatattacc atgtaaaagg
     4321 agctggtctc tatatttagc caatagcccg tctcttttca ggtatcagaa atgtcatcct
     4381 tgtgtctttg agatgatggt ttgaggcccg gcttcttgaa gaagctgtct ggagctggac
     4441 agtgatctat ctcaccactg ttcctaggcc tccctgagac caaatgctgg aagatgcccc
     4501 accccctgta agatgccggc tgtcagcctt ggggacagct gttaggaggt tagagttgga
     4561 gccccatggc ttagctccag ccgctctgat ttcggttgtc atgtcaattt cctaccagaa
     4621 gatccagtcc aaataagtat ttggtgtgga tgctctcagt ggagcatttg gtgtggatgc
     4681 tctcagtggt gggttgcttt cgccctggca ccagtggagg catctttaag tacttggtga
     4741 tgctgaggac aggaccatgt tcctggcatg cggggccctg ggttccatcc cagtgatgaa
     4801 aaaaaatctt cagtatgtgg ggattgtggg gaggcgctgt tctgccatcc cctgagagac
     4861 agcattagtt tctcaggcag ttagtatcag tgcccaggta aaagtctcaa gaggtcccaa
     4921 agggactctc ctccctggaa taaatgactc gatgtctgca gagcggagaa gggacggttg
     4981 ccctctttcc agtttgggga cagaataaca gagattcatc ccagaggcac agccccagtg
     5041 gttgagccat cgtctctcat gccctcgtca ctgagattgt ctttaccctc cagtactcct
     5101 gagactccag acttctacca gacaccatgg caggtacccc taaggtcagt ggctgcctca
     5161 ggctgctttt catctaaacc tttacccagc atgcaaccca tggctcctgc ctggtgagcc
     5221 ttgtgggctg agaaacccaa agcacagcct ccagcgcgtg ggtccaaatg cgtgtgccac
     5281 agtaggggag caccctgccc tcagcacccc atatggtggg acttgccagt atttcaactg
     5341 ttgatacttt tatattttca ctacatttta tatttttata gactatttta tattaaggtt
     5401 ttttctagat tctgtacaac ttttatataa caagttctat tttgtgtgca catctcccct
     5461 gtatgtattt atagcaaccc aagcctctca aattccaggt ccctcttgtg ccaccttttc
     5521 cccttagcct tgactgtcac tctcttctgc tcaccgaggt agcctcgggg gctacttcta
     5581 gccaccatga cagccagaca gcaggaactg gtgtttgtca gctgtggtct gttgatacag
     5641 gaagtactct gggcagtaac ccagtagcta tgttactgca caagcccttc tcgcttagtg
     5701 cagtgatgtc ctggtgcagc cacctgtggg cgggtggctg gacccatcac gaaagtcctt
     5761 gaagacagag gctagatgaa agcccagtgt ctgaggtcct tctgtgggca actggaggac
     5821 ttgagggcac actgccaagt gactgtcctt ttatatccta gcagcttctg tgctcaccct
     5881 tgagttaaat gttagacttt taaaggaaga aataaactaa tttgtattac attctgcctc
     5941 gaaa
//
