LOCUS       NM_001106955            2378 bp    mRNA    linear   ROD 04-JAN-2024
DEFINITION  Rattus norvegicus TBC1 domain family, member 25 (Tbc1d25), mRNA.
ACCESSION   NM_001106955 XM_001063148 XM_217595
VERSION     NM_001106955.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2378)
  AUTHORS   Liu Z, Shang F, Li N and Dong W.
  TITLE     TBC1 domain family member 25 protects against myocardial apoptosis
            and the proinflammatory response triggered by ischemia-reperfusion
            injury through suppression of the TAK1-JNK/p38 MAPK signaling
            cascade
  JOURNAL   In Vitro Cell Dev Biol Anim 59 (10), 796-810 (2023)
   PUBMED   38100060
  REMARK    GeneRIF: TBC1 domain family member 25 protects against myocardial
            apoptosis and the proinflammatory response triggered by
            ischemia-reperfusion injury through suppression of the TAK1-JNK/p38
            MAPK signaling cascade.
REFERENCE   2  (bases 1 to 2378)
  AUTHORS   Itoh T, Kanno E, Uemura T, Waguri S and Fukuda M.
  TITLE     OATL1, a novel autophagosome-resident Rab33B-GAP, regulates
            autophagosomal maturation
  JOURNAL   J Cell Biol 192 (5), 839-853 (2011)
   PUBMED   21383079
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC161862.1.
            
            On Apr 6, 2008 this sequence version replaced NM_001106955.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC161862.1, SRR8487227.118838.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132262, SAMD00132263
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2378
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq12"
     gene            1..2378
                     /gene="Tbc1d25"
                     /gene_synonym="Oatl1; RGD1559711"
                     /note="TBC1 domain family, member 25"
                     /db_xref="GeneID:302552"
                     /db_xref="RGD:1559711"
     exon            1..177
                     /gene="Tbc1d25"
                     /gene_synonym="Oatl1; RGD1559711"
                     /inference="alignment:Splign:2.1.0"
     CDS             55..2121
                     /gene="Tbc1d25"
                     /gene_synonym="Oatl1; RGD1559711"
                     /note="ornithine aminotransferase-like 1"
                     /codon_start=1
                     /product="TBC1 domain family member 25"
                     /protein_id="NP_001100425.1"
                     /db_xref="GeneID:302552"
                     /db_xref="RGD:1559711"
                     /translation="MATTSAASDLACSAAPSPVGGASAAAAVEEEEREVVRVRVKKCE
                     SFLSPEFRSFAVDPQITSLDVLQHILIRAFDLNGKKNFGISYLARDRLGQEAFLSLLS
                     DWDLSTAFATASKPYLQLRVDIRPSEDSPLLEDWDIISPKDVIGSDVLLADKRSSLTT
                     AALPFTQSILSQVGRTLSKVQQVLSWSYGEDVKPFKPPLSDAEFHTYLNHEGQLSRPE
                     ELRLRIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKSREYEQLKSEWAQRV
                     NPEDLEFIRSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLTTYAVTHPQVSYCQGM
                     SDLASPILAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAHLKLLLRHADPDFY
                     QYLQEAGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSSLPPDPPEHEVELVGPPS
                     QVADTGFGSHRGRPVRQRHMLRPAGGGSSAFEDAVVHLATSSQGPSSGGRLLRQASLD
                     GLQQLRDNMSPRKDLLVQLSHPATLISSKSLSEPLLNSPDPLLSSSSRPDSPSSSSPP
                     STQEASPSGDVAVGSPSMPEVGSPRDPGKSVPPPPPMGLPPPQEFGRGNPFMLFLCLA
                     ILLEHRDHIMRNGLDYNELAMHFDRLVRKHHLGRVLRRAKALFADYLQSEVWDSEEGA
                     EATAPS"
     exon            178..287
                     /gene="Tbc1d25"
                     /gene_synonym="Oatl1; RGD1559711"
                     /inference="alignment:Splign:2.1.0"
     exon            288..442
                     /gene="Tbc1d25"
                     /gene_synonym="Oatl1; RGD1559711"
                     /inference="alignment:Splign:2.1.0"
     exon            443..570
                     /gene="Tbc1d25"
                     /gene_synonym="Oatl1; RGD1559711"
                     /inference="alignment:Splign:2.1.0"
     exon            571..759
                     /gene="Tbc1d25"
                     /gene_synonym="Oatl1; RGD1559711"
                     /inference="alignment:Splign:2.1.0"
     exon            760..2342
                     /gene="Tbc1d25"
                     /gene_synonym="Oatl1; RGD1559711"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctggggaag gggcaactat cagttgtcac cgggacagat aagatagcgg cgggatggca
       61 acaacctccg cggcctcgga cttagcgtgc tcggcagcgc cctcgcccgt cggaggtgcc
      121 tcggcagcag cggcggttga agaggaggag cgtgaggtgg tacgggtccg agtcaagaaa
      181 tgtgagagct tcttgtctcc cgagttccgc tcttttgctg tagatcctca gatcacctcg
      241 ctggacgtgt tgcagcatat cctcatccga gcctttgact tgaatgggaa gaagaacttt
      301 ggcatcagct acctggcccg agaccggctc ggacaggaag ctttcctctc cctcctttct
      361 gattgggacc tcagcacagc tttcgccacc gcctccaaac cttatttgca gttgcgtgta
      421 gacattcggc cctcagagga cagcccattg ctggaggact gggacatcat tagccccaaa
      481 gatgtcattg gatctgatgt gctactggcc gacaagcggt cctcactgac gacagccgcc
      541 ttgcctttca cacagtccat cctgtctcag gtgggccgta cactgtctaa ggtccagcaa
      601 gtgctgagtt ggtcttatgg agaagatgtc aagcctttca agccacctct gagtgatgcc
      661 gagttccaca cgtatctgaa tcatgaaggt cagctctccc ggcctgagga gttgcgcttg
      721 aggatctacc acggcggtgt ggagccttca cttcgaaaag tggtatggcg ctacctcctg
      781 aatgtgtacc cagatgggct gacaggccgt gagcggatgg actacatgaa acgtaagagc
      841 cgcgagtacg agcagctcaa aagcgagtgg gcccagcgag tgaaccctga ggacctggaa
      901 ttcatccgaa gcacagtcct caaggatgtg cttcgcacag accgagccca tccctactat
      961 gcagggcctg aggatggccc acatctacgg gccctccatg acttgctcac tacctacgcc
     1021 gttacccacc cacaggtatc gtactgccag ggtatgagtg acctggcctc accaattctt
     1081 gccgtcatgg accacgaagg ccatgccttt gtatgcttct gtggcatcat gaagcgccta
     1141 gctgccaact tccaccctga tggtcgtgcc atggccacca agtttgccca cctcaagctg
     1201 ctgttgagac atgctgaccc agacttctac cagtacctgc aggaagcggg tgccgatgac
     1261 ctctttttct gttaccgctg gctgctgttg gaacttaagc gggagttcgc ctttgatgat
     1321 gctctccgaa tgctagaagt cacctggagt tcactgcctc ctgaccctcc tgaacatgaa
     1381 gtggaactcg ttggaccgcc cagccaagta gcagacactg gctttggtag ccacagggga
     1441 cggccagtac gtcagaggca catgctgagg cctgctggtg gaggaagcag tgcttttgaa
     1501 gacgctgttg tccacttagc tacatctagc cagggaccta gtagtggggg acgtctccta
     1561 agacaggcca gcctagatgg tctccaacaa ctcagggata acatgagccc caggaaggac
     1621 cttctggtcc aactatctca cccagctacc ctcattagct ccaagtccct gtccgagccc
     1681 ttgctgaatt ccccagatcc actcctctcc tcctcttctc ggcccgattc cccatcttcg
     1741 tcgtctcctc catctaccca ggaggcttcc ccttctggtg acgtagctgt aggatccccc
     1801 tcgatgccag aggtagggtc tcccagagac cctgggaagt ctgtaccacc tccacctcca
     1861 atgggccttc ccccacccca ggagtttggc cgagggaacc cattcatgct cttcctctgc
     1921 ctcgctatcc tgctggagca tcgtgaccac atcatgcgca atgggctgga ttacaatgag
     1981 ctagccatgc attttgaccg cctggtgcgg aaacaccatc tagggcgagt cttgcgcaga
     2041 gccaaggctc tctttgctga ttacctacag tctgaagtgt gggactctga ggagggggct
     2101 gaggccacag ctccatcttg attatatccc ctccagcctt ccatccccag tggtactcca
     2161 ttctttgcca tgagggccta cacatgagac cttatttcct gcctgccatc ccagacatgt
     2221 tggagcctgg ggcctcctct ccccaggttt gagtatgtgt ggctcagcgt tggcactgcc
     2281 ccacagaggc catggcctct ttctgttttt gttgtttcta aactatactt tccatacaca
     2341 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//
