LOCUS       NM_001401878            3225 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus TBC1 domain family, member 22a (Tbc1d22a), mRNA.
ACCESSION   NM_001401878 XM_039080324
VERSION     NM_001401878.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3225)
  AUTHORS   Greninger,A.L., Knudsen,G.M., Betegon,M., Burlingame,A.L. and
            DeRisi,J.L.
  TITLE     ACBD3 interaction with TBC1 domain 22 protein is differentially
            affected by enteroviral and kobuviral 3A protein binding
  JOURNAL   mBio 4 (2), e00098-e00013 (2013)
   PUBMED   23572552
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3225)
  AUTHORS   Tempel,W., Tong,Y., Dimov,S., Bochkarev,A. and Park,H.
  TITLE     First crystallographic models of human TBC domains in the context
            of a family-wide structural analysis
  JOURNAL   Proteins 71 (1), 497-502 (2008)
   PUBMED   18186464
REFERENCE   3  (bases 1 to 3225)
  AUTHORS   Yoshimura,S., Egerer,J., Fuchs,E., Haas,A.K. and Barr,F.A.
  TITLE     Functional dissection of Rab GTPases involved in primary cilium
            formation
  JOURNAL   J Cell Biol 178 (3), 363-369 (2007)
   PUBMED   17646400
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Jul 12, 2022 this sequence version replaced NM_001401878.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.28372.1,
                                           SRR26360190.723039.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-189               JAXUCZ010000007.1  119172365-119172553
            190-246             JAXUCZ010000007.1  119190104-119190160
            247-578             JAXUCZ010000007.1  119190897-119191228
            579-755             JAXUCZ010000007.1  119194624-119194800
            756-826             JAXUCZ010000007.1  119251655-119251725
            827-955             JAXUCZ010000007.1  119261392-119261520
            956-1018            JAXUCZ010000007.1  119263291-119263353
            1019-1133           JAXUCZ010000007.1  119271874-119271988
            1134-1243           JAXUCZ010000007.1  119305847-119305956
            1244-1319           JAXUCZ010000007.1  119323329-119323404
            1320-1447           JAXUCZ010000007.1  119350983-119351110
            1448-1543           JAXUCZ010000007.1  119406334-119406429
            1544-3225           JAXUCZ010000007.1  119455590-119457271
FEATURES             Location/Qualifiers
     source          1..3225
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..3225
                     /gene="Tbc1d22a"
                     /gene_synonym="RGD1306588"
                     /note="TBC1 domain family, member 22a"
                     /db_xref="GeneID:689443"
                     /db_xref="RGD:1306588"
     exon            1..189
                     /gene="Tbc1d22a"
                     /gene_synonym="RGD1306588"
                     /inference="alignment:Splign:2.1.0"
     CDS             128..1672
                     /gene="Tbc1d22a"
                     /gene_synonym="RGD1306588"
                     /note="TBC1 domain family member 22A-like"
                     /codon_start=1
                     /product="TBC1 domain family member 22A"
                     /protein_id="NP_001388807.1"
                     /db_xref="GeneID:689443"
                     /db_xref="RGD:1306588"
                     /translation="MASDGARKQFWKRSNSKVPGSIQHVYGAQHPPFDPLLHGTLLKS
                     TPKVPTTPVKAKRVSTFQEFESNTSDAWDAGEDDDELLAMATESLNSEVVMETAHRVL
                     RNHSQRQNQPSQKKPEPEPQPIAEPPVAPSGDLRLVKSVSESHTPCPSESTSDTVPLQ
                     RSQSLPHSATVTLSGTSDTHALGGSALSKRETSRLDKFKQLLAGPNTDLEELRKLSWS
                     GIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYYNSRNDEVHQDTYRQ
                     IHIDIPRMSPEALILQPKVTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEY
                     TDQEDVDKVDVSSVPAEVLRNIEADTYWCMSKLLDGIQDNYTFAQPGIQMKVKMLEEL
                     VSRIDERVHRHLDGHEVRYLQFAFRWMNNLLMRELPLRCTIRLWDTYQSEPEGFSHFH
                     LYVCAAFLVRWRREILEERDFQELLLFLQNLPTARWDDQDVSLLLAEAYRLKFAFADA
                     PNHYKK"
     exon            190..246
                     /gene="Tbc1d22a"
                     /gene_synonym="RGD1306588"
                     /inference="alignment:Splign:2.1.0"
     exon            247..578
                     /gene="Tbc1d22a"
                     /gene_synonym="RGD1306588"
                     /inference="alignment:Splign:2.1.0"
     exon            579..755
                     /gene="Tbc1d22a"
                     /gene_synonym="RGD1306588"
                     /inference="alignment:Splign:2.1.0"
     exon            756..826
                     /gene="Tbc1d22a"
                     /gene_synonym="RGD1306588"
                     /inference="alignment:Splign:2.1.0"
     exon            827..955
                     /gene="Tbc1d22a"
                     /gene_synonym="RGD1306588"
                     /inference="alignment:Splign:2.1.0"
     exon            956..1018
                     /gene="Tbc1d22a"
                     /gene_synonym="RGD1306588"
                     /inference="alignment:Splign:2.1.0"
     exon            1019..1133
                     /gene="Tbc1d22a"
                     /gene_synonym="RGD1306588"
                     /inference="alignment:Splign:2.1.0"
     exon            1134..1243
                     /gene="Tbc1d22a"
                     /gene_synonym="RGD1306588"
                     /inference="alignment:Splign:2.1.0"
     exon            1244..1319
                     /gene="Tbc1d22a"
                     /gene_synonym="RGD1306588"
                     /inference="alignment:Splign:2.1.0"
     exon            1320..1447
                     /gene="Tbc1d22a"
                     /gene_synonym="RGD1306588"
                     /inference="alignment:Splign:2.1.0"
     exon            1448..1543
                     /gene="Tbc1d22a"
                     /gene_synonym="RGD1306588"
                     /inference="alignment:Splign:2.1.0"
     exon            1544..3225
                     /gene="Tbc1d22a"
                     /gene_synonym="RGD1306588"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctctcgggtc tacgctccgg agtcctggta tctctgaggg gccaaccggg cacaggagag
       61 ggccgctgga ggttggccgg ccgctctcgg gtgtcagggt tgcggatctg agggatgagg
      121 agcggccatg gccagcgacg gggccaggaa gcagttctgg aagcgcagca acagcaaggt
      181 cccgggcagc atccagcatg tgtatggagc ccagcaccca ccttttgatc cgctgttaca
      241 cggcaccttg ctcaagtcca cgcccaaggt gcccaccacc ccagtgaagg ccaagcgggt
      301 cagcaccttc caggagtttg agagcaatac cagtgacgct tgggatgcgg gagaagatga
      361 cgatgagctc ctggcaatgg cgacagagag cctgaactct gaggtggtca tggagacagc
      421 acatcgtgtc ctgcgcaatc acagccagag gcagaaccag ccctcacaga agaagccaga
      481 gccagagcct cagcccatag cagagcctcc tgtagctccc agtggcgacc ttcgcctggt
      541 gaagtctgtc agtgagagcc acactccttg tccttcagag agcaccagtg atacagtccc
      601 tctgcagcgg tcccagtctc ttccccactc agccactgtg acactgagtg ggacatctga
      661 cactcatgcc cttggtggct cagccctgag taagagagag acctctcgac tggacaagtt
      721 caaacagctg cttgctggcc ccaacacaga ccttgaggaa ttacggaagc tgagctggtc
      781 cggaatccca aagccagttc gtccaatgac atggaaactt ctctcaggtt accttcctgc
      841 caatgttgac cgaagaccag ccacgctgca gaggaaacag aaggaatact ttgctttcat
      901 tgagcactat tacaactcta ggaatgacga agttcaccag gacacctatc gccagatcca
      961 tattgacatc cctcggatga gcccagaagc actgattctt cagcccaagg tgacagagat
     1021 tttcgaaagg atcttgttta tctgggccat ccgacaccct gccagtggat acgttcaggg
     1081 aataaatgac ctggtcactc cgttcttcgt ggtcttcatt tgcgagtaca cagaccagga
     1141 ggacgtagac aaggtcgatg tctccagcgt gcctgcagag gtgcttcgca acattgaggc
     1201 tgatacctac tggtgcatga gcaagctgct ggatggcatt caggacaact acacctttgc
     1261 ccaaccaggg attcagatga aagtaaagat gctggaagag cttgtgagcc ggattgacga
     1321 gcgagtccac cggcatctgg acgggcacga ggtgaggtac ctgcagtttg cctttcgctg
     1381 gatgaacaac ctgctgatgc gggagctgcc cctgcgctgc accatccgcc tgtgggacac
     1441 ctatcagtct gaacccgagg gcttttctca tttccactta tatgtttgtg ctgctttcct
     1501 cgtgagatgg aggagagaaa ttctagaaga aagagatttt caagagttgc tgctcttcct
     1561 ccagaacctg cctactgccc gctgggatga tcaggacgtc agcctgctgc tggctgaggc
     1621 ctatcgcctc aagtttgcct tcgcagacgc ccccaatcac tacaagaagt gagcctgggg
     1681 cccatggcag tggccttacc ctggggatag tacccctccc tgcctgggca gctgctggcc
     1741 tccggactgg ccctttcctg gtttgaccta gagaatgggc cccagcatgg tccagggctg
     1801 gcaggatagg cagcctcgtt tgatgagata ccaaagagag cccaggagag aatcctagct
     1861 tcagaagctc agtgtggcca ggagttccct cactctggcc ctaccttgcc aaatgccctc
     1921 cctacagccc ccagtccagt cagccaagag gaagtttccc tcagagagcc ctgctatatg
     1981 ggtgccaggc agaggtgggc tgccatctca agcctgctct cgattgcaca aatctgttct
     2041 gtcaagtgaa agaataaagt ccaggaaaaa gtgctgagca tgagttaggc taagctagga
     2101 tttctgcaca cagagccttt gatggccgcc atgcttaggc ttgacttggt ttaaatacag
     2161 ctagatcagg agttggatcc tgggaggctg tggaacaata aaaggccagg gcaggctgag
     2221 gcttctcatg gtcaccttac tttctgtctt taattgcccc actccctgcc cttgtgagga
     2281 gaagggtcaa agaaccccca ggtaggcagg ggcttttgtc agtcagggcc ccagagatta
     2341 tcccaaactt ggccatgaca gggcaggagt tggtggttct agagccccag ctttgtgtag
     2401 ggaggttcct cccaccacca tctggatggc aatagccagg agctgctggg ctggcacccc
     2461 ttcatgccct atggcccctt tccagagcca ctgggttgga gcatttgccc cccattactg
     2521 ggcttctcca gggccctcag actggcttcc cacacgtatt tcccacatat gcccccaggc
     2581 agtctggcct ctgtgatgtg ggatccccaa ggaccaccag gccacctggg gcaagagccg
     2641 caaactcctg tcctcagtta cccactacag cccactctct ggcccgtccc ttcttcagga
     2701 gcagcacacc actgcccagg cactaggact gtgcccagag gctgtgggga agacataggg
     2761 aagagtgtgc ctgcttctgt tcagatcatc ctgggtcaca tggggcgtga catcaacaga
     2821 gtgctgtgca ggcaatccaa tgtcctcgat cagcagaggg acatgcttcc tcagaccagt
     2881 gcctgtcctg ggtaaggagc acccagttat aaggaatgct gcctcggtgg ctctgtggag
     2941 aagcgccatc cttcctgatc cttccatggt gcagatcacc cctcagccag aagggtagac
     3001 ccagaaagat ctgccccatg gtgttttttt tttttaatga gatgacaagg acccatgagg
     3061 ttaacttaag ccctgaatgt atttttatgt gtgcaaatgc ttgactgggt gtacgagacg
     3121 ctggcgacag tcctgtgtct gagccatgag ctgagccggg caggatgtgt gctttgaatg
     3181 tgatgtgttg gaaacacgaa ataaagatgc ttcatatggc ctgtg
//
