LOCUS       NM_001108921            3728 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus TBC1 domain family, member 10b (Tbc1d10b), mRNA.
ACCESSION   NM_001108921 XM_001078373 XM_344965
VERSION     NM_001108921.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3728)
  AUTHORS   Ishibashi K, Kanno E, Itoh T and Fukuda M.
  TITLE     Identification and characterization of a novel Tre-2/Bub2/Cdc16
            (TBC) protein that possesses Rab3A-GAP activity
  JOURNAL   Genes Cells 14 (1), 41-52 (2009)
   PUBMED   19077034
  REMARK    GeneRIF: FLJ13130 is a novel type of Rab-GAP that exhibits broad
            GAP specificity and inactivates several distinct Rab isoforms,
            including Rab3A, just near the plasma membrane.
REFERENCE   2  (bases 1 to 3728)
  AUTHORS   Yoshimura S, Egerer J, Fuchs E, Haas AK and Barr FA.
  TITLE     Functional dissection of Rab GTPases involved in primary cilium
            formation
  JOURNAL   J Cell Biol 178 (3), 363-369 (2007)
   PUBMED   17646400
REFERENCE   3  (bases 1 to 3728)
  AUTHORS   Fuchs E, Haas AK, Spooner RA, Yoshimura S, Lord JM and Barr FA.
  TITLE     Specific Rab GTPase-activating proteins define the Shiga toxin and
            epidermal growth factor uptake pathways
  JOURNAL   J Cell Biol 177 (6), 1133-1143 (2007)
   PUBMED   17562788
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473956.2.
            
            On or before Sep 9, 2010 this sequence version replaced
            XM_001078373.2, XM_344965.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760389,
                              SAMEA5760393 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3728
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q37"
     gene            1..3728
                     /gene="Tbc1d10b"
                     /gene_synonym="RGD1309191"
                     /note="TBC1 domain family, member 10b"
                     /db_xref="GeneID:365372"
                     /db_xref="RGD:1309191"
     exon            1..962
                     /gene="Tbc1d10b"
                     /gene_synonym="RGD1309191"
                     /inference="alignment:Splign:2.1.0"
     CDS             58..2445
                     /gene="Tbc1d10b"
                     /gene_synonym="RGD1309191"
                     /codon_start=1
                     /product="TBC1 domain family member 10B"
                     /protein_id="NP_001102391.1"
                     /db_xref="GeneID:365372"
                     /db_xref="RGD:1309191"
                     /translation="METGPAPLVAPPRRHGASAAPSPPPRGSRAGSVLVVAPGPPVTT
                     ATSAPVDLVVPGEARPAWVPGSLQTSASTPTTATGSTVELTLEASPEAAKTQEFPAPA
                     AEAGAETSVALVLGTDTPKTEEARASPVPGPGTPTRTPSRTASGALTAKPPLAPKPGT
                     TVASGVTARGGAGQVAGGHGAATSASAGPVPEDPSGPVTGPPGTCEASAPVARVTVTP
                     APETTENFQDLGSTSSLGPGISGPRGQAPDTLSYLDSVSLMSGTLESLTDDVSSVGSD
                     SEINGLALRKTDKYGFLGGSQYSGSLESSIPVDVARQRELKWLEMFSNWDKWLSRRFQ
                     KVKLRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEELERAPGDPKWLDVIEKDLHR
                     QFPFHEMFAARGGHGQQDLYRILKAYTIYRPDEGYCQAQAPVAAVLLMHMPAEQAFWC
                     LVQICDKYLPGYYSAGLEAIQLDGEIFFALLRRASPLAHRHLRRQRIDPVLYMTEWFM
                     CIFARTLPWASVLRVWDMFFCEGVKIIFRVALVLLRHTLGSVEKLRSCQGMYETMEQL
                     RNLPQQCMQEDFLVHEVTTLPVTEALIERENAAQLKKWRETRGELQYRPSRRLHGSRA
                     IHEERRRQQPPLGPSSSLLSLPSLKSRGSRAVGGAPSPPPPVRRASAGPVPGAVVIAE
                     GLHPSLPSPTGNSTPLGTSKEIRRQEKERQKQEKEREKERQRQEKEREKQEKERQKWE
                     KEQEKEQQKQEKERQKLEKKGQGRKLSLRRKADGPPAPQDGGDRSAAEARQDAYF"
     exon            963..1062
                     /gene="Tbc1d10b"
                     /gene_synonym="RGD1309191"
                     /inference="alignment:Splign:2.1.0"
     exon            1063..1170
                     /gene="Tbc1d10b"
                     /gene_synonym="RGD1309191"
                     /inference="alignment:Splign:2.1.0"
     exon            1171..1277
                     /gene="Tbc1d10b"
                     /gene_synonym="RGD1309191"
                     /inference="alignment:Splign:2.1.0"
     exon            1278..1392
                     /gene="Tbc1d10b"
                     /gene_synonym="RGD1309191"
                     /inference="alignment:Splign:2.1.0"
     exon            1393..1458
                     /gene="Tbc1d10b"
                     /gene_synonym="RGD1309191"
                     /inference="alignment:Splign:2.1.0"
     exon            1459..1648
                     /gene="Tbc1d10b"
                     /gene_synonym="RGD1309191"
                     /inference="alignment:Splign:2.1.0"
     exon            1649..1803
                     /gene="Tbc1d10b"
                     /gene_synonym="RGD1309191"
                     /inference="alignment:Splign:2.1.0"
     exon            1804..3728
                     /gene="Tbc1d10b"
                     /gene_synonym="RGD1309191"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggggcggcgc cttctgcggc ctccccggcg gggggatgtg aggggcggcc cgcagctatg
       61 gagacgggcc cggcgcccct tgtggccccg ccgcgccgtc acggcgcctc cgctgcccct
      121 tcgcctccgc cccggggttc ccgggccggg tcggtcctag tggtggcacc aggaccgcca
      181 gtgactacgg ccacttcggc ccccgtcgac ctggtggtcc ccggggaggc tcggcccgcc
      241 tgggtcccag gatcgttaca gacctcggcc tcgacaccca cgacagctac aggcagcacg
      301 gtagagctaa ccctggaggc ctcacccgaa gccgcgaaga cgcaagagtt ccccgcacca
      361 gcggcagagg caggagccga gacgtccgtg gccttggttt tggggacaga cactccaaag
      421 acggaagagg ctcgagcctc gcctgtccca ggaccaggga cccccactcg gaccccttcc
      481 agaacggcgt ctggagccct gactgccaaa cccccgcttg cccccaagcc gggaaccaca
      541 gtggcttcag gagtgactgc acggggtgga gcagggcagg tggcaggtgg acatggagct
      601 gctacatcag catcagcagg gccggtgcct gaggaccctt cagggcctgt cacaggccct
      661 cccgggacgt gcgaggcttc ggctccggtg gctagggtga cagtgacccc agctccggag
      721 actactgaaa actttcaaga cctgggttcc acgtccagtc taggacctgg catctctggg
      781 cctcgagggc aggccccgga caccctgagc tacttggact ccgtgagcct catgtctggg
      841 accttggagt ccttgacgga tgatgtgagc tccgtgggtt cagactcgga gataaatggg
      901 ctggccctgc gcaagacgga caagtatggt ttccttgggg gcagccagta ctcaggcagc
      961 ctagagagct ctattcctgt ggatgtggct cggcagcggg agctcaagtg gctggagatg
     1021 ttcagtaact gggataagtg gctgtcacgg cgtttccaga aggtaaagct acgttgccgg
     1081 aaaggaatcc cctcctctct cagagccaag gcctggcagt acctgtctaa tagcaaggaa
     1141 ctcctggagc agaacccggg caagtttgag gagctggaac gggctcctgg ggaccccaag
     1201 tggctggatg tgattgaaaa agacctgcac cgccagttcc ctttccatga gatgtttgct
     1261 gctcgaggag ggcatgggca acaggacctg taccgaatcc tgaaggccta taccatctac
     1321 aggcctgacg agggctactg tcaggcccag gccccagtgg ctgctgtgtt gctcatgcac
     1381 atgcctgctg agcaagcgtt ttggtgcctg gtacagatct gcgacaagta cctcccaggt
     1441 tactacagtg cagggctgga ggccattcag ttggatggag aaattttttt tgcactcctg
     1501 cgccgggctt ctccgctggc acatcgtcac cttcggcgtc agcgcattga cccagtactc
     1561 tacatgacag agtggttcat gtgcatcttt gcccgcaccc tcccctgggc ttcagtgctg
     1621 cgtgtctggg acatgttttt ctgtgaaggc gttaagatca tcttccgagt ggctctggtc
     1681 ttactgcgac acacactggg ctctgtggaa aagctgcgct catgtcaagg catgtatgaa
     1741 accatggagc agcttcggaa cctgccacag cagtgtatgc aggaggactt cctagtgcat
     1801 gaggtaacca ccctccctgt gacagaagca ttgattgagc gggagaatgc agcccaactg
     1861 aagaagtggc gagaaactag gggagagctg cagtatcggc cctccaggcg actacatggc
     1921 tcccgagcca tccatgagga acgcaggcgg cagcagccac ccctgggtcc ttcttctagc
     1981 ctcctcagcc tccctagtct caagagcaga ggctcccggg cagttggagg ggctccttcc
     2041 ccaccacctc ctgtccgcag ggctagtgct gggcctgtcc ctggggctgt cgtcattgct
     2101 gagggactgc atccatccct tccttcacct actggcaaca gcaccccact aggcaccagc
     2161 aaggagatca ggcgacagga gaaagagcgg cagaaacagg agaaagagcg agagaaggag
     2221 cggcagagac aggagaagga gcgggaaaag caagagaagg agcggcagaa gtgggagaaa
     2281 gagcaagaga aggaacagca gaagcaggaa aaggaacggc agaagctgga gaagaagggc
     2341 caaggccgga aactttcctt gcgtcgaaag gcagatgggc ccccagcacc ccaggatggt
     2401 ggggacaggt cagcagctga ggcccggcag gatgcttact tttgacctct tgttgggtct
     2461 ggatggcatg accctcctcc tctccctcag ccaacagcag ccctggcagg gctctcccag
     2521 ctcccttggc aggctcttcc tttttctaag gaaagtggct tgattcccct gactccttgc
     2581 cagctgctga tccctacatg gccgggacag ccacagtgca tgggacagct acatttccta
     2641 gggtaacagt gaccaagtct ggagactctt tcgtccagtt aggctcagct tgggtctctg
     2701 tcacgcctat gaagttcttc tggggtgctg tcttaatttg cctttggtca ccacagtgac
     2761 tcttggcaat ggcagttagc agattcttac actccagtgg cttcccttag atggtggagc
     2821 taggttcctt ttcctgtctt ggggccctgc ctgtcatccc actgttttct gggggccaag
     2881 gctgttttct ctcctggata tccttgtgtt gtaattatgt acagaaggtc agattggcct
     2941 ggggtgggtg ctctgtcctt tccccattcc acagtgcgtc tacgctccag tttatttaag
     3001 aggatatgtt aggaagtgtc ctccgtttcc ttcccaccca tgtcctgctc tttcctagcc
     3061 cacttgctct gtatgttcag gcctctctgc tgagagtcag aaagcctatc tttcattttg
     3121 ttcccttcca gccatcaagc ccctctctga ataagggtct tcccttgagt ccagggggtg
     3181 gaacccaatg tttacattct cttctgtctt ggtcccaccc cagtggcagt ttcgtggcgc
     3241 tttgaggaac cggaaaaaga acctgctgtt ctatctggat ctgtctcctg ccttgttatt
     3301 tgaagagtgc tatagagtaa gggggaagga gccaggaaga aagtctgact ctccataggt
     3361 tcagtctgct gatcttggca ggaacatcta gaccactggt tctcaacctt cttttttttt
     3421 ttttttgttc ttttttttcg gagctgggga ccgaacccag ggccttgcgc ttcctaggta
     3481 agcgctctac cactgagcta aatccccagc ccctctcaac cttcttaatg ctgtgaccct
     3541 ttaatacagt tcttcacatt gtggtgactc caaccataaa actattttca ttattactta
     3601 ataacagttt actactgctg tgaatcataa tataagtttc tgtgttttct gatagtctta
     3661 ggcaacccct gtgaatagta ttcgaccccc aaaatgagtc acagtaaacc cttgctccat
     3721 ctctcatc
//
