LOCUS       XM_006251004            4802 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus TBC1 domain family member 1 (Tbc1d1),
            transcript variant X1, mRNA.
ACCESSION   XM_006251004
VERSION     XM_006251004.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051349.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006251004.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006251004.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4802
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4802
                     /gene="Tbc1d1"
                     /note="TBC1 domain family member 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 17
                     ESTs, 4 long SRA reads, 7 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 15 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:360937"
                     /db_xref="RGD:1304562"
     CDS             752..4525
                     /gene="Tbc1d1"
                     /codon_start=1
                     /product="TBC1 domain family member 1 isoform X1"
                     /protein_id="XP_006251066.1"
                     /db_xref="GeneID:360937"
                     /db_xref="RGD:1304562"
                     /translation="MEAITFTARKHPFPNEVSVDFGLQLVGSLPVHSLTTMPMLPWVV
                     AEVRRLSGQCSKKEPGMKQVRLWVSPSGLRCEPDLRKSQPWDPLICSSIFECKPQRVH
                     KLIHNSQDPSYFACLIKEDAAHQQSLCYVFKADDQTKVPEIISSIRQAGKIARQEELR
                     CPSEFDDTFAKKFEVLFCGRVTVAHKKAPPALIDECIEKFNHVSCGRRIDWDAPTGQP
                     SAPGARPMRKSFSQPGLRSLAFRKEFQDASLRSSTFSSFDNDIENHLIGGHNVVQPTD
                     MEENRTMLFTIGQSEVYLISPDTKKIALEKNFKEISFCSQGIRHVDHFGFICRECSGG
                     GGAGFHFVCYVFQCTNEALVDEIMMTLKQAFTVAAVQQTAKAPAQLCEGCPLQGLHKL
                     CERIEGMNSSKTKLELQKHLTTLTNQEQAMIFEEVQKLRPRNEQRENELIISFLRCLY
                     EEKQKEHSHTGEPKQTLQVAAENIGSELPPSASRFRLDSLKNRAKRSLTESLESILSR
                     GNKARGLQDHSASVDLDSSTSSTLSNTSKELSMGDKEALPISESSFKLLGSSDDLSSD
                     SESHIAEESALLSPQQAFRRRANTLSHFPVECPAPPEPAQTSPGVSQRKLMRYHSVST
                     ETPHERNVDHLPGGESRCCPGQPSDPPPLPPRLNPSASSPNFFKYLKHNSSGEQSGNA
                     VPKSVSYRNALRKKLHSSSSVPNFLKFLAPVDENNTCDFKNTNRDFESKANHLGDTDG
                     TPVKARRHSWRQQIFLRVATPQKACDSPSRYEDYSELGELPPRSPLEPVCEDGPFGPV
                     QEEKKKTSRELRELWKKAILQQILLLRMEKENQKLQASENDLLNKRLKLDYEEITPCL
                     KEVTTVWEKMLSTPGRSKIKFDMEKVHSAVGQGVPRHHRGEIWKFLAEQFHLKHPFPS
                     KQQPKDVPYKELLKKLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLL
                     DQEVGYCQGLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLS
                     RLLHDYHRDLYNHLEEYEIGPSLYAAPWFLTVFASQFPLGFVARVFDMIFLQGSEVIF
                     KVALSLLGSHKPLILQHENLETIVDFIKNTLPNLGLVQMEKTISQVFEMDIAKQLQAY
                     EVEYHVLQEELIDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANARIQSLEVTV
                     EKLLTSESKLKQAVLTLEMERSALLQMVEELRRQMAQPSTAEPDCTRLEPTGD"
ORIGIN      
        1 gtccgtttcg gaggagtgcg tgcagagaag caggattcct gcgggagcgc gggctccact
       61 accacctgct gagagcctcg caggccaaag cagccccagg cagggctacc tgctataaat
      121 aagcggtcaa gaacccggtg tgtgactaca catcccgccg cgagggccgt aatcacttgt
      181 gagcacgcag ggaatattct gggccaggac ttcgcgctga ggctggatgg agcggcgatc
      241 gttgcacctt ccccgagctc tcgtggggtg gcgccaggtg gcccctgggc cggctgagga
      301 tggaccgctg gggagcaagg ggagggaggc cgcggaggac ccgcactgca gcagctgttg
      361 ctcgcctgtg actcgccagt ctgggctgag tcccttagcc agagtcgcgt gctactgctg
      421 tcgccgccgc gggccacacc gcggagcctg ttgctgcaag ccacctcgta cccgccgtct
      481 cttcaacccg caagagaagc agatactgtg gagcggtccc catcccaaca gcgtggggcc
      541 gcaagagcgc agccagctga ggaccataga cgccccgccc gcccaggcca tcttctgggt
      601 gccccggagc acctgagcgc cccagatcag ccccgagttc tgagcgcgcc accacactgg
      661 atgctgccct cagaagcatg tgaaatagat tacttcattt atagtaggaa aatagtagca
      721 agctttcttg gctttccaga cctctcccaa gatggaggca atcacattca cagcgaggaa
      781 gcatccgttc cctaacgagg tttcggtgga cttcggcttg cagctagtgg gctccttacc
      841 cgtgcattct ctcactacaa tgcccatgct gccgtgggtg gtagccgagg tacgaagact
      901 cagtggccag tgctccaaaa aggagcctgg gatgaagcaa gtccgccttt gggtttcgcc
      961 ctccggacta cggtgcgaac ctgacctgag gaaaagtcaa ccgtgggacc ccctgatctg
     1021 ttccagcatc tttgagtgca agcctcagcg tgttcacaaa ctgattcaca acagtcagga
     1081 cccgagctac ttcgcttgtc tcattaagga ggacgctgcc caccagcaga gcctctgcta
     1141 tgtatttaaa gcagatgatc aaacaaaagt gcctgagatc attagctcca tccggcaggc
     1201 agggaagatt gcccgccagg aagagctgcg ctgcccctcg gagttcgatg acaccttcgc
     1261 caaaaagttt gaggtgctct tctgtggccg ggtcactgtg gcccacaaga aggcaccacc
     1321 tgcactgatc gacgagtgta tcgagaagtt caaccatgtg agctgtggcc gcagaataga
     1381 ctgggatgcg cccacggggc aaccatcagc gcctggggcc cggcccatgc gcaaatcctt
     1441 ctcacagcct ggactgcgct cgctggcctt caggaaggag ttccaggatg ctagcctccg
     1501 cagtagcacc tttagctcct tcgataacga catcgaaaat cacctaatcg gcgggcacaa
     1561 tgtagttcag cccacagaca tggaggagaa ccgaactatg ctcttcacga ttggccaatc
     1621 tgaagtttac ctcatcagtc ctgacaccaa aaagattgca ttggagaaaa attttaagga
     1681 gatatccttt tgctctcagg gcatcaggca cgtggaccac tttggattta tctgccgaga
     1741 gtgctcaggt ggcggtggcg ccggctttca ttttgtctgt tacgtgttcc agtgcacaaa
     1801 tgaagctctg gttgacgaga tcatgatgac tctgaagcag gctttcacgg tagctgcagt
     1861 gcagcagact gctaaggcac cagcccagct gtgtgagggc tgccccttgc agggcctaca
     1921 caagctctgc gagaggatag agggaatgaa ttcatctaaa accaaattag aactccagaa
     1981 gcacctgacc acactgacca atcaggagca ggcaatgata tttgaggaag ttcagaaatt
     2041 gagaccaaga aacgagcagc gagagaatga attaattatt tcttttctga ggtgtttata
     2101 cgaagagaaa caaaaggaac acagccatac tggggagcca aagcagacac tgcaggtggc
     2161 agcagagaat attgggagtg aactaccacc cagtgctagc cggttcaggt tagattcact
     2221 gaagaacaga gcaaagaggt ccttaacaga gtccttagag agcattctgt cccggggcaa
     2281 taaagccagg ggccttcagg accattccgc cagtgtggat ctggacagct ccacttctag
     2341 tactctaagt aacaccagca aagagctgtc catgggtgac aaggaggcct tgcccatctc
     2401 tgaaagctcc ttcaaactcc ttggctcctc agatgaccta tccagtgact cagagagcca
     2461 cattgcagaa gagtctgctc tgttgtcacc ccagcaggca ttcagaagga gagccaacac
     2521 cctgagtcat ttcccagttg agtgccctgc acctccagaa cctgcccaga cctctccagg
     2581 ggtgtctcaa agaaaactca tgcggtatca ctccgtgagc acagagacgc ctcatgaacg
     2641 caatgtggac catcttcctg ggggtgagtc tcggtgctgc ccagggcagc cttcagatcc
     2701 gcctcctctt ccccctcgtc ttaacccttc cgcctcctca ccaaactttt ttaagtacct
     2761 aaaacacaat tccagtggag aacagagtgg aaatgctgtg ccaaaaagtg tctcctaccg
     2821 taatgccctg cggaaaaaac tccattcttc ctcttctgtg ccaaattttc taaaatttct
     2881 ggctcctgta gatgaaaata acacctgtga ctttaagaac acaaacaggg actttgaatc
     2941 caaagcaaac cacctgggtg acacagatgg gaccccagtg aaggcccggc ggcattcatg
     3001 gagacagcag atattcctcc gagtggccac tccacagaag gcttgtgatt ctccaagcag
     3061 atatgaagat tattcagagc tgggagagct ccctccacgt tcccctttag aaccagtgtg
     3121 tgaagatgga ccatttggtc cagtacaaga ggagaagaag aaaacgtctc gtgagcttag
     3181 agagctgtgg aaaaaggcca tcttgcagca gatcctgctg ctgaggatgg agaaggagaa
     3241 ccagaagcta caagcctctg agaatgattt gctgaacaaa cgcctgaagc ttgattatga
     3301 ggaaatcact ccttgtctta aagaagtaac tacagtgtgg gaaaagatgc ttagcactcc
     3361 aggaagatcc aaaattaagt ttgatatgga aaaagtgcac tcagctgttg ggcaaggtgt
     3421 gccacgtcat caccggggtg agatctggaa gtttctagct gagcagttcc accttaaaca
     3481 tccatttccc agtaaacagc agccaaagga tgtgccctac aaagagctct tgaagaagct
     3541 gacctcccag cagcacgcca tcctcattga cctcgggcga acctttccaa cacatccata
     3601 cttctctgcc cagcttggag caggtcagct gtcactttac aacattctga aggcctactc
     3661 acttctggac caggaagttg gatactgtca aggtctcagc ttcgtggcag gcattttgct
     3721 ccttcatatg agtgaggaag aagcattcaa gatgctcaag ttcctgatgt ttgacatggg
     3781 gctgcggaaa cagtatcggc cagacatgat tattttacag atccagatgt accagctgtc
     3841 acggctcctc catgattacc acagagacct ctacaaccac ctggaagagt atgagatcgg
     3901 ccccagcctc tacgcagctc cctggtttct caccgtgttc gcctcacagt tcccacttgg
     3961 ctttgtagcc agagtctttg atatgatctt ccttcaggga tcagaggtca tatttaaagt
     4021 agctttaagt cttttgggga gccataaacc cttgattctg cagcatgaga acctggaaac
     4081 catagtggac ttcataaaga acacactccc caacctaggc ttggtgcaga tggagaagac
     4141 catcagtcag gtgtttgaga tggacatcgc caaacagcta caagcctatg aggttgagta
     4201 ccatgtgctc caagaagaac ttattgattc ctctcctctc agtgacaacc aaagaatgga
     4261 taaattggag aaaaccaata gcagcttgcg caaacagaac cttgacctcc tggaacaatt
     4321 gcaggtggca aatgctagga tccaaagcct cgaagtcacg gtggagaagc ttcttaccag
     4381 cgagagtaag ctgaaacagg ctgtgctgac cctggagatg gagcgctccg ccctgctgca
     4441 gatggtggag gagctacgga ggcaaatggc ccagcccagc actgcagagc cggactgcac
     4501 ccggctggaa cctacaggtg actgacagct gccaggagag actgcgcgtg caccacttac
     4561 actgtccggg ccttaatgga gagagggaag ctggaagcag agaagagaga gcttctcagg
     4621 gaggaaactg gctgaccagc ctgcagattc ttttgagctc agaatttgga attggaggac
     4681 aaaagtctca gagttattgt tgtttttggt tctaattcgt cccctttcca gtcctggttg
     4741 ttgtagcttt agatggtgtg ggcgtgaata aattacatgt atggttcctc ctccttcagg
     4801 ga
//
