LOCUS       NM_001025150             960 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus taste receptor, type 2, member 144 (Tas2r144),
            mRNA.
ACCESSION   NM_001025150 XM_575452
VERSION     NM_001025150.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 960)
  AUTHORS   Tomas,J., Santos,C.R.A., Duarte,A.C., Maltez,M., Quintela,T.,
            Lemos,M.C. and Goncalves,I.
  TITLE     Bitter taste signaling mediated by Tas2r144 is down-regulated by
            17beta-estradiol and progesterone in the rat choroid plexus
  JOURNAL   Mol Cell Endocrinol 495, 110521 (2019)
   PUBMED   31352039
  REMARK    GeneRIF: the bitter receptors Tas2r109, Tas2r144, and the
            taste-related genes Plcb2 and Trpm5 were down-regulated by ovarian
            hormones
REFERENCE   2  (bases 1 to 960)
  AUTHORS   Meyerhof,W., Batram,C., Kuhn,C., Brockhoff,A., Chudoba,E., Bufe,B.,
            Appendino,G. and Behrens,M.
  TITLE     The molecular receptive ranges of human TAS2R bitter taste
            receptors
  JOURNAL   Chem Senses 35 (2), 157-170 (2010)
   PUBMED   20022913
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY362738.1.
            
            On Jul 1, 2005 this sequence version replaced XM_575452.1.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..960
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q24"
     gene            1..960
                     /gene="Tas2r144"
                     /gene_synonym="RGD1562314; Tas2r40"
                     /note="taste receptor, type 2, member 144"
                     /db_xref="GeneID:500101"
                     /db_xref="RGD:1562314"
     CDS             1..960
                     /gene="Tas2r144"
                     /gene_synonym="RGD1562314; Tas2r40"
                     /note="T2R18; T2R40; taste receptor type 2 member 18;
                     taste receptor, type 2, member 40"
                     /codon_start=1
                     /product="taste receptor type 2 member 40"
                     /protein_id="NP_001020321.1"
                     /db_xref="GeneID:500101"
                     /db_xref="RGD:1562314"
                     /translation="MAIITTDSDYYTHRYEVIIPFVVSTIDCIVGIIGNGFITVIYGT
                     ELVRSKRLPTGEHLMLMLSFSRLLLQIWIMVEITYQLFFPMIYNHNAMYKLFKTISVF
                     LNYCNLWFAAWLNVFYCLKIVNFAHPLFLMMKQKIVVLMPRLMSLSVLVSISLSSFFS
                     KDIFNVYMNTSVPIPFSNSTKMKYFFKTNVLNLAFLYYMGIFIPLFMFIMAAILLITS
                     LKRHTLNMESSTTGSRDSSMEAHLGAIKSTSYSLILYIINALALFISMSNIFGAYSTW
                     NSVCSFILTAYPAGQSVHLILRNPGLRRAWRRFQHHVRLYLKR"
     exon            1..960
                     /gene="Tas2r144"
                     /gene_synonym="RGD1562314; Tas2r40"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggcaataa taaccacaga ttccgactac tatactcaca ggtatgaagt gataatccct
       61 ttcgtggtct cgaccataga ttgtatcgtc ggcatcattg gcaatggctt catcacagtc
      121 atatatggga ctgaattggt caggagcaaa agactcccca ctggtgagca ccttatgttg
      181 atgttgagtt tttccaggct cttgctacag atctggataa tggtagagat tacctatcaa
      241 ctatttttcc ccatgattta taaccataat gccatgtata aactattcaa aaccatctct
      301 gtgtttctga actactgtaa cctctggttt gccgcgtggc tcaatgtctt ctattgtctt
      361 aaaattgtga actttgctca ccctctgttt cttatgatga agcagaaaat cgtagtgttg
      421 atgcctcggc tcatgagtct gtcagtgttg gtttccatca gcttaagctc cttcttctct
      481 aaagacatct tcaatgtgta tatgaatact tcagttccca tccctttctc caactccaca
      541 aagatgaagt acttctttaa gaccaatgta ctcaacctgg ctttcttata ttatatgggg
      601 atcttcattc ctttgttcat gttcatcatg gcagccattc tgctcatcac ctcactcaag
      661 aggcacaccc tgaacatgga aagcagcacc acaggctcta gggactccag catggaggct
      721 cacttgggtg ccatcaaatc gaccagctac tctctcattc tctacattat caatgcactg
      781 gctctattta tttccatgtc aaatatcttt ggtgcctata gtacctggaa tagtgtgtgc
      841 agctttatcc tgaccgccta tccagctgga cagtcagtgc atctgatctt gagaaaccca
      901 gggctgagaa gagcctggag gcggtttcag caccacgttc gactttacct taaaagatag
//
