LOCUS       NM_023993               1008 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus taste receptor, type 2, member 119 (Tas2r119),
            mRNA.
ACCESSION   NM_023993
VERSION     NM_023993.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1008)
  AUTHORS   Dehkordi,O., Rose,J.E., Fatemi,M., Allard,J.S., Balan,K.V.,
            Young,J.K., Fatima,S., Millis,R.M. and Jayam-Trouth,A.
  TITLE     Neuronal expression of bitter taste receptors and downstream
            signaling molecules in the rat brainstem
  JOURNAL   Brain Res 1475, 1-10 (2012)
   PUBMED   22836012
  REMARK    GeneRIF: T2R1, a receptor for bitter taste, is expressed in
            brainstem.
REFERENCE   2  (bases 1 to 1008)
  AUTHORS   Meyerhof,W., Batram,C., Kuhn,C., Brockhoff,A., Chudoba,E., Bufe,B.,
            Appendino,G. and Behrens,M.
  TITLE     The molecular receptive ranges of human TAS2R bitter taste
            receptors
  JOURNAL   Chem Senses 35 (2), 157-170 (2010)
   PUBMED   20022913
REFERENCE   3  (bases 1 to 1008)
  AUTHORS   Zhang,Y., Hoon,M.A., Chandrashekar,J., Mueller,K.L., Cook,B.,
            Wu,D., Zuker,C.S. and Ryba,N.J.
  TITLE     Coding of sweet, bitter, and umami tastes: different receptor cells
            sharing similar signaling pathways
  JOURNAL   Cell 112 (3), 293-301 (2003)
   PUBMED   12581520
REFERENCE   4  (bases 1 to 1008)
  AUTHORS   Montmayeur,J.P. and Matsunami,H.
  TITLE     Receptors for bitter and sweet taste
  JOURNAL   Curr Opin Neurobiol 12 (4), 366-371 (2002)
   PUBMED   12139982
  REMARK    Review article
REFERENCE   5  (bases 1 to 1008)
  AUTHORS   Wu,S.V., Rozengurt,N., Yang,M., Young,S.H., Sinnett-Smith,J. and
            Rozengurt,E.
  TITLE     Expression of bitter taste receptors of the T2R family in the
            gastrointestinal tract and enteroendocrine STC-1 cells
  JOURNAL   Proc Natl Acad Sci U S A 99 (4), 2392-2397 (2002)
   PUBMED   11854532
REFERENCE   6  (bases 1 to 1008)
  AUTHORS   Margolskee,R.F.
  TITLE     Molecular mechanisms of bitter and sweet taste transduction
  JOURNAL   J Biol Chem 277 (1), 1-4 (2002)
   PUBMED   11696554
  REMARK    Review article
REFERENCE   7  (bases 1 to 1008)
  AUTHORS   Chandrashekar,J., Mueller,K.L., Hoon,M.A., Adler,E., Feng,L.,
            Guo,W., Zuker,C.S. and Ryba,N.J.
  TITLE     T2Rs function as bitter taste receptors
  JOURNAL   Cell 100 (6), 703-711 (2000)
   PUBMED   10761935
REFERENCE   8  (bases 1 to 1008)
  AUTHORS   Adler,E., Hoon,M.A., Mueller,K.L., Chandrashekar,J., Ryba,N.J. and
            Zuker,C.S.
  TITLE     A novel family of mammalian taste receptors
  JOURNAL   Cell 100 (6), 693-702 (2000)
   PUBMED   10761934
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF227140.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AF227140.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1008
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q23"
     gene            1..1008
                     /gene="Tas2r119"
                     /gene_synonym="T2R1; Tas2r1"
                     /note="taste receptor, type 2, member 119"
                     /db_xref="GeneID:78979"
                     /db_xref="RGD:620733"
     CDS             1..1008
                     /gene="Tas2r119"
                     /gene_synonym="T2R1; Tas2r1"
                     /note="T2R19; T2R119; taste receptor type 2 member 1;
                     taste receptor type 2 member 19"
                     /codon_start=1
                     /product="taste receptor type 2 member 119"
                     /protein_id="NP_076483.1"
                     /db_xref="GeneID:78979"
                     /db_xref="RGD:620733"
                     /translation="MMEGHILFFFLVVMVQFVTGVLANGLIVVVHAIDLIMWKKMAPL
                     DLLLFCLATSRIILQLCILFAQLCLFSLVRHTLFEDNITFVFIINELSLWFATWLGVF
                     YCAKIATIPHPLFLWLKMRISRLVPWLILGSVLYVIITTFIHSRETSAILKPIFISLF
                     PKNATQVGTGHATLLSVLVLGLTLPLFIFTVAVLLLIYSLWNYSRQMRTMVGTREYSG
                     HAHISAMLSILSFLILYLSHYMVAVLISTQVLYLGSRTFVFCLLVIGMYPSIHSIVLI
                     LGNPKLKRNAKMFIVHCKCCHCTRAWVTSRSPRLSDLPVPPTHPSANKTSCSEACIMP
                     S"
     exon            1..1008
                     /gene="Tas2r119"
                     /gene_synonym="T2R1; Tas2r1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgatggaag ggcatatact cttcttcttt ttggttgtga tggtgcagtt tgtcactggg
       61 gtcttggcaa atggcctcat tgtggttgtc catgctattg acttgatcat gtggaagaaa
      121 atggccccgt tggatctgct tctattttgc ctggcgactt ctcggatcat tctgcagtta
      181 tgtatattgt ttgcacaatt gtgtctattc tctttggtga gacacacttt atttgaggac
      241 aatattacct ttgtcttcat cataaatgaa ctgagtcttt ggtttgctac atggctcggt
      301 gttttctact gtgccaagat tgctaccatt cctcacccac tctttctgtg gctgaagatg
      361 aggatatcca ggttggtacc atggctgatc ctgggatctg tgctctatgt aattattact
      421 actttcatcc atagcagaga gacttcagca atccttaaac caatttttat aagccttttt
      481 cctaaaaatg caactcaagt cggaacaggg catgccacac tactctcagt cctggtcctt
      541 gggctcacac tgccgttgtt catctttact gttgctgttc tgctcttgat atactccctg
      601 tggaattata gcaggcagat gaggactatg gtaggcacca gggagtatag cggacatgct
      661 cacatcagtg caatgctgtc cattctatca ttcctcatcc tctatctctc ccactacatg
      721 gtggctgttc tgatctctac tcaagtcctc taccttggaa gcagaacctt tgtattctgc
      781 ttactggtta ttggtatgta cccctcaata cactcgattg tcttaatttt aggaaatcct
      841 aagctgaaac gaaatgcaaa aatgttcatt gtccattgta agtgttgtca ttgtacaaga
      901 gcttgggtca cctcaaggag cccaagactc agtgacttgc cagtgcctcc tactcatccc
      961 tcagccaaca agacatcctg ctcagaagcc tgtataatgc catcctaa
//
