LOCUS       NM_023999                930 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus taste receptor, type 2, member 105 (Tas2r105),
            mRNA.
ACCESSION   NM_023999
VERSION     NM_023999.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 930)
  AUTHORS   Zhang,Y., Hoon,M.A., Chandrashekar,J., Mueller,K.L., Cook,B.,
            Wu,D., Zuker,C.S. and Ryba,N.J.
  TITLE     Coding of sweet, bitter, and umami tastes: different receptor cells
            sharing similar signaling pathways
  JOURNAL   Cell 112 (3), 293-301 (2003)
   PUBMED   12581520
REFERENCE   2  (bases 1 to 930)
  AUTHORS   Bufe,B., Hofmann,T., Krautwurst,D., Raguse,J.D. and Meyerhof,W.
  TITLE     The human TAS2R16 receptor mediates bitter taste in response to
            beta-glucopyranosides
  JOURNAL   Nat Genet 32 (3), 397-401 (2002)
   PUBMED   12379855
REFERENCE   3  (bases 1 to 930)
  AUTHORS   Montmayeur,J.P. and Matsunami,H.
  TITLE     Receptors for bitter and sweet taste
  JOURNAL   Curr Opin Neurobiol 12 (4), 366-371 (2002)
   PUBMED   12139982
  REMARK    Review article
REFERENCE   4  (bases 1 to 930)
  AUTHORS   Wu,S.V., Rozengurt,N., Yang,M., Young,S.H., Sinnett-Smith,J. and
            Rozengurt,E.
  TITLE     Expression of bitter taste receptors of the T2R family in the
            gastrointestinal tract and enteroendocrine STC-1 cells
  JOURNAL   Proc Natl Acad Sci U S A 99 (4), 2392-2397 (2002)
   PUBMED   11854532
REFERENCE   5  (bases 1 to 930)
  AUTHORS   Margolskee,R.F.
  TITLE     Molecular mechanisms of bitter and sweet taste transduction
  JOURNAL   J Biol Chem 277 (1), 1-4 (2002)
   PUBMED   11696554
  REMARK    Review article
REFERENCE   6  (bases 1 to 930)
  AUTHORS   Chandrashekar,J., Mueller,K.L., Hoon,M.A., Adler,E., Feng,L.,
            Guo,W., Zuker,C.S. and Ryba,N.J.
  TITLE     T2Rs function as bitter taste receptors
  JOURNAL   Cell 100 (6), 703-711 (2000)
   PUBMED   10761935
REFERENCE   7  (bases 1 to 930)
  AUTHORS   Adler,E., Hoon,M.A., Mueller,K.L., Chandrashekar,J., Ryba,N.J. and
            Zuker,C.S.
  TITLE     A novel family of mammalian taste receptors
  JOURNAL   Cell 100 (6), 693-702 (2000)
   PUBMED   10761934
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF227146.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AF227146.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..930
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..930
                     /gene="Tas2r105"
                     /gene_synonym="T2R9"
                     /note="taste receptor, type 2, member 105"
                     /db_xref="GeneID:78985"
                     /db_xref="RGD:620741"
     CDS             1..930
                     /gene="Tas2r105"
                     /gene_synonym="T2R9"
                     /note="T2R105; taste receptor type 2 member 9; taste
                     receptor T2R9"
                     /codon_start=1
                     /product="taste receptor type 2 member 105"
                     /protein_id="NP_076489.1"
                     /db_xref="GeneID:78985"
                     /db_xref="RGD:620741"
                     /translation="MLSAAEGILLSIATVEAGLGVLGNTFIALVNCMDWAKNKKLSKI
                     GFLLFGLATSRIFIVWILILDAYAKLFFPGKYLSKSLTEIISCIWMTVNHMTVWFATS
                     LSIFYFLKIANFSHYIFLWLKRRTDKVFAFLLWCLLISWAISFSFTVKVMKSNPKNHG
                     NRTSGTHWEKREFTSNYVLINIGVISLLIMTLTACFLLIISLWKHSRQMQSNVSGFRD
                     LNTEAHVKAIKFLISFIILFILYFIGVAVEIICMFIPENKLLFIFGLTTASVYPCCHS
                     VILILTNSQLKQAFVKVLEGLKFSENGKDLRAT"
     exon            1..930
                     /gene="Tas2r105"
                     /gene_synonym="T2R9"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgctcagtg cagcagaagg catccttctt tccattgcaa ctgttgaagc tgggctggga
       61 gttttaggga acacatttat cgccctggtt aactgcatgg attgggccaa gaacaagaag
      121 ctctctaaga ttggtttcct tctctttggc ttagcaactt ccagaatttt tattgtatgg
      181 atattaattt tagacgcata tgcaaagcta ttctttccgg ggaagtattt gtctaagagt
      241 ctgactgaaa tcatctcttg tatatggatg actgtgaatc acatgactgt ctggtttgcc
      301 accagcctca gcatcttcta tttcctaaaa atagcaaatt tttcccacta tatatttctc
      361 tggttaaaga ggagaactga taaagtattt gcctttctct tgtggtgttt attaatttca
      421 tgggcaatct ccttctcatt cactgtgaaa gtgatgaaga gcaatccaaa gaatcatgga
      481 aacaggacca gtgggacaca ttgggagaag agagaattca caagtaacta tgttttaatc
      541 aatattggag tcatttctct cttgatcatg accttaactg catgtttctt gttaattatt
      601 tcactttgga aacacagcag gcagatgcag tctaatgttt caggattcag agatctcaac
      661 actgaagctc atgtgaaagc cataaaattt ttaatttcat ttatcatcct tttcatcttg
      721 tactttatag gtgttgcagt agaaatcatc tgcatgttta tcccagaaaa caaactgcta
      781 tttatttttg gtttgacaac tgcatccgtc tatccctgct gtcactcagt cattctaatt
      841 ctaacaaaca gccagctgaa gcaagccttt gtaaaggtac tggagggatt aaagttctct
      901 gagaacggaa aagatctcag ggccacatga
//
