LOCUS       NM_053305               2679 bp    mRNA    linear   ROD 29-JUL-2024
DEFINITION  Rattus norvegicus taste 1 receptor member 1 (Tas1r1), mRNA.
ACCESSION   NM_053305 XM_001076331 XM_342986
VERSION     NM_053305.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2679)
  AUTHORS   Li,X., Staszewski,L., Xu,H., Durick,K., Zoller,M. and Adler,E.
  TITLE     Human receptors for sweet and umami taste
  JOURNAL   Proc Natl Acad Sci U S A 99 (7), 4692-4696 (2002)
   PUBMED   11917125
REFERENCE   2  (bases 1 to 2679)
  AUTHORS   Hoon,M.A., Adler,E., Lindemeier,J., Battey,J.F., Ryba,N.J. and
            Zuker,C.S.
  TITLE     Putative mammalian taste receptors: a class of taste-specific GPCRs
            with distinct topographic selectivity
  JOURNAL   Cell 96 (4), 541-551 (1999)
   PUBMED   10052456
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AF127389.1 and CR460546.1.
            
            On or before Oct 28, 2007 this sequence version replaced
            XM_342986.2, XM_001076331.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF127389.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760494 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2520              AF127389.1         1-2520
            2521-2679           CR460546.1         7-165               c
FEATURES             Location/Qualifiers
     source          1..2679
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="W"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..2679
                     /gene="Tas1r1"
                     /gene_synonym="Gpr70"
                     /note="taste 1 receptor member 1"
                     /db_xref="GeneID:29407"
                     /db_xref="RGD:61891"
     CDS             1..2523
                     /gene="Tas1r1"
                     /gene_synonym="Gpr70"
                     /note="G-protein coupled receptor 70; taste receptor, type
                     1, member 1"
                     /codon_start=1
                     /product="taste receptor type 1 member 1 precursor"
                     /protein_id="NP_445757.1"
                     /db_xref="GeneID:29407"
                     /db_xref="RGD:61891"
                     /translation="MLFWAAHLLLSLQLVYCWAFSCQRTESSPGFSLPGDFLLAGLFS
                     LHGDCLQVRHRPLVTSCDRPDSFNGHGYHLFQAMRFTVEEINNSSALLPNITLGYELY
                     DVCSESANVYATLRVLALQGPRHIEIQKDLRNHSSKVVAFIGPDNTDHAVTTAALLGP
                     FLMPLVSYEASSVVLSAKRKFPSFLRTVPSDRHQVEVMVQLLQSFGWVWISLIGSYGD
                     YGQLGVQALEELAVPRGICVAFKDIVPFSARVGDPRMQSMMQHLAQARTTVVVVFSNR
                     HLARVFFRSVVLANLTGKVWVASEDWAISTYITSVTGIQGIGTVLGVAVQQRQVPGLK
                     EFEESYVRAVTAAPSACPEGSWCSTNQLCRECHTFTTRNMPTLGAFSMSAAYRVYEAV
                     YAVAHGLHQLLGCTSEICSRGPVYPWQLLQQIYKVNFLLHENTVAFDDNGDTLGYYDI
                     IAWDWNGPEWTFEIIGSASLSPVHLDINKTKIQWHGKNNQVPVSVCTTDCLAGHHRVV
                     VGSHHCCFECVPCEAGTFLNMSELHICQPCGTEEWAPKESTTCFPRTVEFLAWHEPIS
                     LVLIAANTLLLLLLVGTAGLFAWHFHTPVVRSAGGRLCFLMLGSLVAGSCSFYSFFGE
                     PTVPACLLRQPLFSLGFAIFLSCLTIRSFQLVIIFKFSTKVPTFYRTWAQNHGAGLFV
                     IVSSTVHLLICLTWLVMWTPRPTREYQRFPHLVILECTEVNSVGFLLAFTHNILLSIS
                     TFVCSYLGKELPENYNEAKCVTFSLLLNFVSWIAFFTMASIYQGSYLPAVNVLAGLTT
                     LSGGFSGYFLPKCYVILCRPELNNTEHFQASIQDYTRRCGTT"
     exon            1..188
                     /gene="Tas1r1"
                     /gene_synonym="Gpr70"
                     /inference="alignment:Splign:2.1.0"
     exon            189..495
                     /gene="Tas1r1"
                     /gene_synonym="Gpr70"
                     /inference="alignment:Splign:2.1.0"
     exon            496..1257
                     /gene="Tas1r1"
                     /gene_synonym="Gpr70"
                     /inference="alignment:Splign:2.1.0"
     exon            1258..1470
                     /gene="Tas1r1"
                     /gene_synonym="Gpr70"
                     /inference="alignment:Splign:2.1.0"
     exon            1471..1591
                     /gene="Tas1r1"
                     /gene_synonym="Gpr70"
                     /inference="alignment:Splign:2.1.0"
     exon            1592..2679
                     /gene="Tas1r1"
                     /gene_synonym="Gpr70"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgctcttct gggctgctca cctgctgctc agcctgcagt tggtctactg ctgggctttc
       61 agctgccaaa ggacagagtc ctctccaggc ttcagccttc ctggggactt cctccttgca
      121 ggtctgttct ccctccatgg tgactgtctg caggtgagac acagacctct ggtgacaagt
      181 tgtgacaggc ccgacagctt caacggccat ggctaccacc tcttccaagc catgcggttc
      241 actgttgagg agataaacaa ctcctcggcc ctgcttccca acatcaccct ggggtatgag
      301 ctgtacgacg tgtgctcaga atctgccaat gtgtatgcca ccctgagggt gcttgccctg
      361 caagggcccc gccacataga gatacagaaa gaccttcgca accactcctc caaggtggtg
      421 gccttcatcg ggcctgacaa cactgaccac gctgtcacta ccgctgcctt gctgggtcct
      481 ttcctgatgc ccctggtcag ctatgaggca agcagcgtgg tactcagtgc caagcgcaag
      541 ttcccgtctt tccttcgtac cgtccccagt gaccggcacc aggtggaggt catggtgcag
      601 ctgctgcaga gttttgggtg ggtgtggatc tcgctcattg gcagctacgg tgattacggg
      661 cagctgggtg tgcaggcgct ggaggagctg gccgtgcccc ggggcatctg cgtcgccttc
      721 aaggacatcg tgcctttctc tgcccgggtg ggtgacccga ggatgcagag catgatgcag
      781 catctggctc aggccaggac caccgtggtt gtggtcttct ctaaccggca cctggctaga
      841 gtgttcttca ggtccgtggt gctggccaac ctgactggca aagtgtgggt cgcctcagaa
      901 gactgggcca tctccacgta catcaccagc gtgactggga tccaaggcat tgggacggtg
      961 ctcggtgtgg ccgtccagca gagacaagtc cctgggctga aggagtttga ggagtcttat
     1021 gtcagggctg taacagctgc tcccagcgct tgcccggagg ggtcctggtg cagcactaac
     1081 cagctgtgcc gggagtgcca cacgttcacg actcgtaaca tgcccacgct tggagccttc
     1141 tccatgagtg ccgcctacag agtgtatgag gctgtgtacg ctgtggccca cggcctccac
     1201 cagctcctgg gatgtacttc tgagatctgt tccagaggcc cagtctaccc ctggcagctt
     1261 cttcagcaga tctacaaggt gaattttctt ctacatgaga atactgtggc atttgatgac
     1321 aacggggaca ctctaggtta ctacgacatc atcgcctggg actggaatgg acctgaatgg
     1381 acctttgaga tcattggctc tgcctcactg tctccagttc atctggacat aaataagaca
     1441 aaaatccagt ggcacgggaa gaacaatcag gtgcctgtgt cagtgtgtac cacggactgt
     1501 ctggcagggc accacagggt ggttgtgggt tcccaccact gctgctttga gtgtgtgccc
     1561 tgcgaagctg ggacctttct caacatgagt gagcttcaca tctgccagcc ttgtggaaca
     1621 gaagaatggg cacccaagga gagcactact tgcttcccac gcacggtgga gttcttggct
     1681 tggcatgaac ccatctcttt ggtgctaata gcagctaaca cgctattgct gctgctgctg
     1741 gttgggactg ctggcctgtt tgcctggcat tttcacacac ctgtagtgag gtcagctggg
     1801 ggtaggctgt gcttcctcat gctgggttcc ctggtggccg gaagttgcag cttctatagc
     1861 ttcttcgggg agcccacggt gcccgcgtgc ttgctgcgtc agcccctctt ttctctcggg
     1921 tttgccatct tcctctcctg cctgacaatc cgctccttcc aactggtcat catcttcaag
     1981 ttttctacca aggtgcccac attctaccgt acctgggccc aaaaccatgg tgcaggtcta
     2041 ttcgtcattg tcagctccac ggtccatttg ctcatctgtc tcacatggct tgtaatgtgg
     2101 accccacgac ccaccaggga ataccagcgc ttcccccatc tggtgattct cgagtgcaca
     2161 gaggtcaact ctgtaggctt cctgttggct ttcacccaca acattctcct ctccatcagt
     2221 accttcgtct gcagctacct gggtaaggaa ctgccagaga actataatga agccaaatgt
     2281 gtcaccttca gcctgctcct caacttcgta tcctggatcg ccttcttcac catggccagc
     2341 atttaccagg gcagctacct gcctgcggtc aatgtgctgg cagggctgac cacactgagc
     2401 ggcggcttca gcggttactt cctccccaag tgctatgtga ttctctgccg tccagaactc
     2461 aacaatacag aacactttca ggcctccatc caggactaca cgaggcgctg cggcactacc
     2521 tgatccactg gaaaggtgca gacgggaagg aagcctctct tcttgtgctg aaggtggcgg
     2581 gtccagtggg gccgagagct tgaggtgtct gggagagctc cggcacagct tacgatgtat
     2641 aagcacgcgg aagaatccag tgcaataaag acgggaagt
//
