LOCUS       NM_001401535            3185 bp    mRNA    linear   ROD 08-APR-2024
DEFINITION  Rattus norvegicus threonyl-tRNA synthetase 3 (Tars3), mRNA.
ACCESSION   NM_001401535 XM_039112659
VERSION     NM_001401535.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3185)
  AUTHORS   Chen,Y., Ruan,Z.R., Wang,Y., Huang,Q., Xue,M.Q., Zhou,X.L. and
            Wang,E.D.
  TITLE     A threonyl-tRNA synthetase-like protein has tRNA aminoacylation and
            editing activities
  JOURNAL   Nucleic Acids Res 46 (7), 3643-3656 (2018)
   PUBMED   29579307
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Feb 15, 2022 this sequence version replaced XM_039112659.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ224737.1, SRR26643297.1927.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-314               JAXUCZ010000001.1  128623701-128624014
            315-383             JAXUCZ010000001.1  128624985-128625053
            384-574             JAXUCZ010000001.1  128626284-128626474
            575-698             JAXUCZ010000001.1  128631830-128631953
            699-820             JAXUCZ010000001.1  128635168-128635289
            821-938             JAXUCZ010000001.1  128638380-128638497
            939-1003            JAXUCZ010000001.1  128641017-128641081
            1004-1082           JAXUCZ010000001.1  128642013-128642091
            1083-1229           JAXUCZ010000001.1  128644386-128644532
            1230-1328           JAXUCZ010000001.1  128645361-128645459
            1329-1495           JAXUCZ010000001.1  128657602-128657768
            1496-1658           JAXUCZ010000001.1  128659649-128659811
            1659-1796           JAXUCZ010000001.1  128664117-128664254
            1797-1874           JAXUCZ010000001.1  128667280-128667357
            1875-1975           JAXUCZ010000001.1  128667528-128667628
            1976-2080           JAXUCZ010000001.1  128670600-128670704
            2081-2153           JAXUCZ010000001.1  128672604-128672676
            2154-2268           JAXUCZ010000001.1  128673649-128673763
            2269-3185           JAXUCZ010000001.1  128675062-128675978
FEATURES             Location/Qualifiers
     source          1..3185
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..3185
                     /gene="Tars3"
                     /gene_synonym="RGD1311308; Tarsl2"
                     /note="threonyl-tRNA synthetase 3"
                     /db_xref="GeneID:308701"
                     /db_xref="RGD:1311308"
     exon            1..314
                     /gene="Tars3"
                     /gene_synonym="RGD1311308; Tarsl2"
                     /inference="alignment:Splign:2.1.0"
     CDS             45..2417
                     /gene="Tars3"
                     /gene_synonym="RGD1311308; Tarsl2"
                     /EC_number="6.1.1.3"
                     /note="probable threonyl-tRNA synthetase 2, cytoplasmic;
                     probable threonine--tRNA ligase 2, cytoplasmic;
                     threonyl-tRNA synthetase-like 2"
                     /codon_start=1
                     /product="threonine--tRNA ligase 2, cytoplasmic"
                     /protein_id="NP_001388464.1"
                     /db_xref="GeneID:308701"
                     /db_xref="RGD:1311308"
                     /translation="MAAQALAAQAVASRLQRQEEDIRWLCAEVQRLRDEQLRGPERGQ
                     AEGPRLTREVAQLQAENRDLHQRLCDLRLRLAEQGGPGARRAAAHEPPTQNQEKDTKR
                     KRLKDSEPNREVKQPNFIKERLQLFETLKTDHQLLPATQEKKNTNNVISVRVAGGKTV
                     QGEEWKTTPYQVAAGISKELAENTVIAKVNGVLWDLDRPLEGDSTVELLMFDNEEAQA
                     VYWHSSAHVLGEAMELYYGGHLCYGPPIENGFYYDMFIGDRVVSSTELSALENICKTI
                     IKEKQPFERLEVSKDSLLEMFKYNKFKCRILKEKVDTPTTTVYRCGPLIDLCKGPHVR
                     HTGKIKAIKIFKNSSTYWEGNPEMETLQRVYGISFPDSKMMRDWEKFQEEARSRDHRK
                     IGKEQELFFFHDLSPGSCFFLPRGAFIYNTLMDFIREEYHKRNFTEVLSPNMYNSKLW
                     ETSGHWQHYSNNMFTFDIEKDTFALKPMNCPGHCLMFAHRPRSWREMPVRFADFGVLH
                     RNELSGTLTGLTRVRRFQQDDAHIFCMVEQIEEEIKGCLHFLQSVYSTFGFSFQLNLS
                     TRPEHFLGETEIWDEAERQLQNSLTGFGKPWKINPGDGAFYGPKIDIKIKDAIGRYHQ
                     CATIQLDFQLPIRFNLTYVSKDGDDKNRPVIIHRAILGSVERMIAILSENYGGKWPLW
                     LSPRQVMIIPVGPACENYALQVSKECFEEGFMADVDLDDSCTLNKKIRNAQLAQYNFI
                     LVVGEKEKLNNSVNVRTRDNKIHGEISITSVIEKLKNLKKSRTLNAEEEF"
     exon            315..383
                     /gene="Tars3"
                     /gene_synonym="RGD1311308; Tarsl2"
                     /inference="alignment:Splign:2.1.0"
     exon            384..574
                     /gene="Tars3"
                     /gene_synonym="RGD1311308; Tarsl2"
                     /inference="alignment:Splign:2.1.0"
     exon            575..698
                     /gene="Tars3"
                     /gene_synonym="RGD1311308; Tarsl2"
                     /inference="alignment:Splign:2.1.0"
     exon            699..820
                     /gene="Tars3"
                     /gene_synonym="RGD1311308; Tarsl2"
                     /inference="alignment:Splign:2.1.0"
     exon            821..938
                     /gene="Tars3"
                     /gene_synonym="RGD1311308; Tarsl2"
                     /inference="alignment:Splign:2.1.0"
     exon            939..1003
                     /gene="Tars3"
                     /gene_synonym="RGD1311308; Tarsl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1004..1082
                     /gene="Tars3"
                     /gene_synonym="RGD1311308; Tarsl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1083..1229
                     /gene="Tars3"
                     /gene_synonym="RGD1311308; Tarsl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1230..1328
                     /gene="Tars3"
                     /gene_synonym="RGD1311308; Tarsl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1329..1495
                     /gene="Tars3"
                     /gene_synonym="RGD1311308; Tarsl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1496..1658
                     /gene="Tars3"
                     /gene_synonym="RGD1311308; Tarsl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1659..1796
                     /gene="Tars3"
                     /gene_synonym="RGD1311308; Tarsl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1797..1874
                     /gene="Tars3"
                     /gene_synonym="RGD1311308; Tarsl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1875..1975
                     /gene="Tars3"
                     /gene_synonym="RGD1311308; Tarsl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1976..2080
                     /gene="Tars3"
                     /gene_synonym="RGD1311308; Tarsl2"
                     /inference="alignment:Splign:2.1.0"
     exon            2081..2153
                     /gene="Tars3"
                     /gene_synonym="RGD1311308; Tarsl2"
                     /inference="alignment:Splign:2.1.0"
     exon            2154..2268
                     /gene="Tars3"
                     /gene_synonym="RGD1311308; Tarsl2"
                     /inference="alignment:Splign:2.1.0"
     exon            2269..3185
                     /gene="Tars3"
                     /gene_synonym="RGD1311308; Tarsl2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actctgactg ggccggcggg ctcaggtggc acaaggaggc tgccatggcg gcccaggccc
       61 tggccgctca ggcggtggcc tcgcgcctgc agcggcagga ggaggacatt cgctggctgt
      121 gcgcggaggt gcagcgcctg agggacgagc agctgcgcgg gccggagcgg ggccaagccg
      181 agggcccgcg cctgacgcgc gaggtggcac agctccaggc ggagaaccgc gacctgcacc
      241 agcgcctgtg tgacctgcgg ctgcgcctgg cggagcaggg aggccccggg gcccggcgag
      301 cggcggcgca cgagcctcct actcaaaacc aagagaagga cacgaagagg aagaggttga
      361 aggattctga gcccaacagg gaggtgaagc aaccgaattt tataaaagag agattgcagc
      421 tttttgaaac gttgaagaca gatcatcagc tgttacctgc tactcaggaa aagaagaaca
      481 caaacaatgt gatttcagtg agggtggctg gtgggaagac tgtgcaagga gaagaatgga
      541 aaacaacacc ttatcaagtg gctgctggga ttagtaaaga actggctgaa aatacagtaa
      601 ttgccaaggt gaatggtgtt ttatgggacc tggaccgccc gttggaaggg gactccactg
      661 tagagcttct gatgtttgac aatgaggaag cccaggctgt gtactggcac tccagcgctc
      721 acgtcctggg ggaggccatg gagctgtact atggaggcca cctgtgctac ggcccaccca
      781 ttgaaaatgg attctattat gatatgttca ttggagacag agtggtgtcc agcacggagc
      841 tgtctgccct ggagaacata tgtaaaacta tcatcaaaga aaagcaaccg tttgaaagac
      901 tggaagtcag caaggacagt ctcctggaaa tgtttaagta caataaattt aagtgccgga
      961 ttctgaagga gaaagttgac actccgacaa ccactgttta caggtgtggt ccactgattg
     1021 acctttgtaa aggcccccat gtaagacaca ctggaaaaat taaagccata aaaatattca
     1081 agaactcctc aacatattgg gaagggaacc ctgagatgga aacattgcag agggtctacg
     1141 gcatatcctt tcctgacagc aaaatgatga gagactggga aaaattccaa gaggaggcca
     1201 ggagccggga ccacaggaaa atcgggaagg aacaagagct tttcttcttc catgatctga
     1261 gcccaggaag ctgttttttc ctcccaagag gagcgttcat ttacaataca cttatggatt
     1321 tcatacgaga ggaatatcac aaacgtaact tcacagaagt gctctctcct aacatgtaca
     1381 acagtaagct ctgggaaact tcaggccatt ggcagcatta cagtaacaac atgttcacct
     1441 ttgacattga aaaggacact ttcgccctca aacccatgaa ctgtccaggg cactgtttaa
     1501 tgtttgcaca ccgcccacga tcctggaggg aaatgcctgt tagatttgcc gactttggcg
     1561 ttcttcacag aaacgaactg tcggggactt taaccggctt aacccgagtg aggcgcttcc
     1621 agcaggatga cgcccacatc ttctgcatgg tggagcagat tgaagaagaa ataaaggggt
     1681 gcttgcactt tttacagtct gtttactcaa cattcggctt ctcctttcaa ttaaacctgt
     1741 cgacaaggcc tgagcacttc ctaggagaga ctgagatatg ggacgaagct gaaaggcaac
     1801 tgcagaatag cttgacggga tttggaaaac cttggaaaat aaacccagga gatggagcat
     1861 tctatggccc taaaattgat ataaaaatta aggatgctat cggcagatac catcagtgtg
     1921 cgacaatcca gctggacttc caactgccta ttaggtttaa cctcacatat gttagtaagg
     1981 atggggatga caagaacagg cctgtgatca ttcaccgagc catcctggga tctgtggaaa
     2041 ggatgatagc cattctctca gagaactacg gggggaaatg gcctctctgg ctgtctcctc
     2101 gccaggtaat gatcatccct gtaggcccag cttgtgaaaa ctacgctcta caggtgtcaa
     2161 aggaatgctt cgaagaaggc ttcatggccg acgtggactt agatgacagt tgtacactaa
     2221 ataagaaaat acggaatgca cagctggctc agtataattt tattttggtg gttggtgaaa
     2281 aggaaaagct aaacaattca gtaaatgtgc gaacaagaga caacaaaatt catggagaaa
     2341 tatcaataac ttcagtcatt gaaaaattga agaacctcaa aaaatcacgt acgctaaatg
     2401 ccgaggaaga attctgaagt cttccccttg tgcttctcta taactttgtt ttgacctctg
     2461 aaaatgcact ttccctgtca cttaagatac tagttctttt aagaacccta gggccacttg
     2521 tagggctcca atgagttcaa ccttagaagc aaaagtgatt atttgatata aacaaaattt
     2581 taattcactg tgttctgaga ctaaataaaa gatggagaaa tttgcaagat aagaagactc
     2641 cagagaccta agtggtaaaa tggtgttcat tcaaaggaag gaacaccagt gagaattatc
     2701 agaaattaag ctttgtttct ttctcagaag atgtgcttcc agcctgtggg ctgtagcttc
     2761 ctgactagag catccacgtt gcatgtgtga gtcctgaact ccgtccccaa cggccactgc
     2821 ccctcaccca acaacgacag aaacgacttt caataaaagc ccatggtcct ttctgaacat
     2881 ggaagggagg tgtcttattt tctaatacac acatctcagg tgtttttatg gctgttttac
     2941 taaagttcac atggaaatgt catgcccaaa gttggaattg atacttcatt tagtcagcaa
     3001 tcataagaga agtactaata ttgtgctagc ggcaaaggac tatgaaactt caaagaaaat
     3061 ttgtggaatc ggttatttgc gctgtgggtt gagagtggca gttttaatgc ttataattaa
     3121 taattcctta tttatcttta aacactaaat tcttaaataa aatgcatcac ttgctgtttc
     3181 tagaa
//
