LOCUS       XM_039109697            2993 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus TAR DNA binding protein (Tardbp),
            transcript variant X3, mRNA.
ACCESSION   XM_039109697
VERSION     XM_039109697.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051340.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039109697.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2993
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..2993
                     /gene="Tardbp"
                     /gene_synonym="Tdp-43"
                     /note="TAR DNA binding protein; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 144
                     ESTs, 11 long SRA reads, 9 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 49 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:298648"
                     /db_xref="RGD:1310906"
     CDS             347..1591
                     /gene="Tardbp"
                     /gene_synonym="Tdp-43"
                     /codon_start=1
                     /product="TAR DNA-binding protein 43 isoform X1"
                     /protein_id="XP_038965625.1"
                     /db_xref="GeneID:298648"
                     /db_xref="RGD:1310906"
                     /translation="MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYR
                     NPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDNKRKMDEADASSAVKVKRAVQK
                     TSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVK
                     VMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVV
                     DVFIPKPFRAFAFVTFADDKVAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRF
                     GGNPGGFGNQGGFGNSRGGGAGLGNNQGGNMGGGMNFGAFSINPAMMAAAQAALQSSW
                     GMMGMLASQQNQSGPSGNNQSQGSMQREPNQAFGSGNNSYSGSNSGAPLGWGSASNAG
                     SGSGFNGGFGSSMDSKSSGWGM"
ORIGIN      
        1 gggcgggggt gggggagaaa tcaacgttgt ctgtcgcgca tggccttctg ggaagtggcg
       61 gcctacctca aggagtatca gtcgttgctc ccttgacgcc caagtttagc cagacctttc
      121 cgaaaatgag gaatagaact gcggggtctc tgttctgaac gtcggttttc gtgctccacc
      181 ggcacggtca agatttagcc aattgaatgc attgctaatt tcttacactt aaagcacgtg
      241 ctaagcccga tttaggctct caggctttag aattaatgaa atgagttcag aatagtcgaa
      301 aaatactgta gactgtaatc tgtgcactcc agagatttaa gcaaagatgt ctgaatatat
      361 tcgggtaaca gaagatgaga atgatgagcc cattgaaata ccatcagaag acgatgggac
      421 agtgttgctg tccacagtta cagcccagtt tccaggggcg tgtggcctgc gctaccggaa
      481 tccagtgtct cagtgtatga gaggtgtccg actggtggaa ggaattctgc atgccccaga
      541 tgctggctgg ggcaatctgg tctatgttgt caactatccc aaagataaca aaaggaaaat
      601 ggatgaggcg gatgcttcct ctgcagtgaa agtgaaaaga gcagtccaga agacatctga
      661 cctcatagtg ttgggtctcc cctggaaaac aacagagcag gacctaaaag actacttcag
      721 tacttttgga gaggttctta tggttcaggt caagaaagat cttaaaactg gtcactcaaa
      781 agggtttggc tttgttcgat ttacggaata tgaaactcaa gtgaaagtaa tgtcacagcg
      841 acatatgata gatgggcgat ggtgtgactg taaacttcca aattctaagc aaagcccaga
      901 cgagcctttg agaagcagaa aggtgtttgt tggacgttgt acagaggaca tgactgctga
      961 agagcttcag cagttcttct gtcagtatgg agaagtggta gatgtcttca ttcccaaacc
     1021 attcagagct tttgcctttg ttacctttgc agatgataag gttgcccagt ctctttgtgg
     1081 agaggacttg atcattaaag gaatcagcgt gcatatatcc aatgctgaac ctaagcataa
     1141 tagcaataga cagttagaaa gaagtggaag atttggtggt aatccaggtg gctttgggaa
     1201 tcagggtggg tttggtaaca gtagaggggg tggagctggc ttgggaaata accagggtgg
     1261 taatatgggt ggagggatga attttggtgc ttttagcatt aatccagcga tgatggctgc
     1321 agctcaggca gcgttacaga gcagttgggg tatgatgggc atgttagcca gccagcagaa
     1381 ccagtcaggc ccatctggga ataaccaaag ccagggcagc atgcagaggg aaccaaatca
     1441 ggcttttggt tctggaaata actcttacag tggttctaat tctggtgccc cccttggttg
     1501 ggggtcagca tcaaatgcag gatcaggcag tggttttaat ggaggctttg gctcaagcat
     1561 ggattctaaa tcctctggct ggggaatgta ggtgggtggg ggtggttagt aggttggttg
     1621 gtaggttagg taggtttaga atggtgggat tcaaattttt ctaaactcat ggtaagtata
     1681 ttgtaaaata catatgtact aaaattttca gattggtttg ttcagtgtgg agtatattca
     1741 gcagtatttt tgacattttt ctttagaaaa aagagggaaa aactaaatga attttataag
     1801 ttttgttata taaagggtta aaatactgag tgggtgaaag tgaactgctg tttgcctaat
     1861 tggtaaacca acactacaat tgatctcaga aggtttctct gtaatattct atcattggaa
     1921 ttgttaatga attctttgca tgttcagagt agaaaccatt ggttagaact acattctttt
     1981 ctccttattt taatttgaat cccaccctat gaatttcttc cttaggaaaa tctccatttg
     2041 ggagatcatg atgtcatggt gtttggttct tttggttttg tttttaacac ttgtcttcct
     2101 tcatatacga aagtacaata tgaagccttc atttaatctc tgcagttcat ctcatttcaa
     2161 atgtttatgg aagaagcact tcattgaaag tagtgctgta aatattctgc cataggaata
     2221 cttctgtcta catgctttct catccaagaa ttcgtcatca cgctgcacag gctgcgtctt
     2281 tgacggtggg tgttccattt ttatccgcta ctctttattt catggaatcg tatcaacgct
     2341 atgaacgcaa ggctgtgata tggaaccaga aggctgtttg aacttttgaa accttgtgtg
     2401 ggattgatgg tggtgccgag gcatgaaagg ctagtatgag cgagaaaagg agagagcgcg
     2461 tgcagagact tggtggtgga aaatggatat tttttaactt ggagagatgt gtccctcaat
     2521 cctgtggctt tggtgcgaga gtgtgcagag agcaatgata gcagataact aacgtacgag
     2581 tgtttctgca tcagaggaca tccacgtctg ttggaagact ttgagttttg ttcttaggaa
     2641 acccacagta gctgaatgtg ttaagtgaaa tacttgtact tccctcccct ctgtcaactg
     2701 ctgtgaatgc tgtatggtgt gtgttctcct ctgttactga tctggaagtg tgggaacgtg
     2761 aactgaagct gatgggctgc gaacatggac tgagcttgtg gtgtgctttg caggagaact
     2821 tggaagcaga gttcaccagt gagctcaggt gtctcaaaga agggtggaag ttctcatgtc
     2881 tgttagctat tcataagaat gctgtttgct gcagttctgt gtcctgtgct tggatgcttt
     2941 ttataagagt tgtcattgtt ggaaattctt aaataaaact gatttaaata ata
//
