LOCUS       XM_008764235            2080 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus TAR DNA binding protein (Tardbp),
            transcript variant X10, mRNA.
ACCESSION   XM_008764235
VERSION     XM_008764235.3
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051340.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_008764235.4.
            
            On Jan 21, 2021 this sequence version replaced XM_008764235.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2080
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..2080
                     /gene="Tardbp"
                     /gene_synonym="Tdp-43"
                     /note="TAR DNA binding protein; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 122
                     ESTs, 7 long SRA reads, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 40 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:298648"
                     /db_xref="RGD:1310906"
     CDS             254..1138
                     /gene="Tardbp"
                     /gene_synonym="Tdp-43"
                     /codon_start=1
                     /product="TAR DNA-binding protein 43 isoform X5"
                     /protein_id="XP_008762457.1"
                     /db_xref="GeneID:298648"
                     /db_xref="RGD:1310906"
                     /translation="MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYR
                     NPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDNKRKMDEADASSAVKVKRAVQK
                     TSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVK
                     VMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVV
                     DVFIPKPFRAFAFVTFADDKVAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRF
                     GGNPGGFGNQGKSPFGRS"
ORIGIN      
        1 tcctctgttc tgcacgccga agggcctgct agtatccgag ccgcgtcgag gatagagcgt
       61 ctctggcgac tctcggagag ctcccctcct gacaggaagc aattgggaga ggccgaaggc
      121 gggcgagggc gggaggcggc cctagcgcca ttttgtgggc acgaagcggt agctcggctg
      181 ttgttgggtt cctttccgtc ttcgatcctt cgttgtgctt cctagcagcg gcccagtgga
      241 gatttaagca aagatgtctg aatatattcg ggtaacagaa gatgagaatg atgagcccat
      301 tgaaatacca tcagaagacg atgggacagt gttgctgtcc acagttacag cccagtttcc
      361 aggggcgtgt ggcctgcgct accggaatcc agtgtctcag tgtatgagag gtgtccgact
      421 ggtggaagga attctgcatg ccccagatgc tggctggggc aatctggtct atgttgtcaa
      481 ctatcccaaa gataacaaaa ggaaaatgga tgaggcggat gcttcctctg cagtgaaagt
      541 gaaaagagca gtccagaaga catctgacct catagtgttg ggtctcccct ggaaaacaac
      601 agagcaggac ctaaaagact acttcagtac ttttggagag gttcttatgg ttcaggtcaa
      661 gaaagatctt aaaactggtc actcaaaagg gtttggcttt gttcgattta cggaatatga
      721 aactcaagtg aaagtaatgt cacagcgaca tatgatagat gggcgatggt gtgactgtaa
      781 acttccaaat tctaagcaaa gcccagacga gcctttgaga agcagaaagg tgtttgttgg
      841 acgttgtaca gaggacatga ctgctgaaga gcttcagcag ttcttctgtc agtatggaga
      901 agtggtagat gtcttcattc ccaaaccatt cagagctttt gcctttgtta cctttgcaga
      961 tgataaggtt gcccagtctc tttgtggaga ggacttgatc attaaaggaa tcagcgtgca
     1021 tatatccaat gctgaaccta agcataatag caatagacag ttagaaagaa gtggaagatt
     1081 tggtggtaat ccaggtggct ttgggaatca gggaaaatct ccatttggga gatcatgatg
     1141 tcatggtgtt tggttctttt ggttttgttt ttaacacttg tcttccttca tatacgaaag
     1201 tacaatatga agccttcatt taatctctgc agttcatctc atttcaaatg tttatggaag
     1261 aagcacttca ttgaaagtag tgctgtaaat attctgccat aggaatactt ctgtctacat
     1321 gctttctcat ccaagaattc gtcatcacgc tgcacaggct gcgtctttga cggtgggtgt
     1381 tccattttta tccgctactc tttatttcat ggaatcgtat caacgctatg aacgcaaggc
     1441 tgtgatatgg aaccagaagg ctgtttgaac ttttgaaacc ttgtgtggga ttgatggtgg
     1501 tgccgaggca tgaaaggcta gtatgagcga gaaaaggaga gagcgcgtgc agagacttgg
     1561 tggtggaaaa tggatatttt ttaacttgga gagatgtgtc cctcaatcct gtggctttgg
     1621 tgcgagagtg tgcagagagc aatgatagca gataactaac gtacgagtgt ttctgcatca
     1681 gaggacatcc acgtctgttg gaagactttg agttttgttc ttaggaaacc cacagtagct
     1741 gaatgtgtta agtgaaatac ttgtacttcc ctcccctctg tcaactgctg tgaatgctgt
     1801 atggtgtgtg ttctcctctg ttactgatct ggaagtgtgg gaacgtgaac tgaagctgat
     1861 gggctgcgaa catggactga gcttgtggtg tgctttgcag gagaacttgg aagcagagtt
     1921 caccagtgag ctcaggtgtc tcaaagaagg gtggaagttc tcatgtctgt tagctattca
     1981 taagaatgct gtttgctgca gttctgtgtc ctgtgcttgg atgcttttta taagagttgt
     2041 cattgttgga aattcttaaa taaaactgat ttaaataata
//
