LOCUS       NM_001108323            1571 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus transport and golgi organization 2 homolog
            (Tango2), mRNA.
ACCESSION   NM_001108323 XM_001063969 XM_341010
VERSION     NM_001108323.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1571)
  AUTHORS   Lalani SR, Liu P, Rosenfeld JA, Watkin LB, Chiang T, Leduc MS, Zhu
            W, Ding Y, Pan S, Vetrini F, Miyake CY, Shinawi M, Gambin T,
            Eldomery MK, Akdemir ZH, Emrick L, Wilnai Y, Schelley S, Koenig MK,
            Memon N, Farach LS, Coe BP, Azamian M, Hernandez P, Zapata G,
            Jhangiani SN, Muzny DM, Lotze T, Clark G, Wilfong A, Northrup H,
            Adesina A, Bacino CA, Scaglia F, Bonnen PE, Crosson J, Duis J,
            Maegawa GH, Coman D, Inwood A, McGill J, Boerwinkle E, Graham B,
            Beaudet A, Eng CM, Hanchard NA, Xia F, Orange JS, Gibbs RA, Lupski
            JR and Yang Y.
  TITLE     Recurrent Muscle Weakness with Rhabdomyolysis, Metabolic Crises,
            and Cardiac Arrhythmia Due to Bi-allelic TANGO2 Mutations
  JOURNAL   Am J Hum Genet 98 (2), 347-357 (2016)
   PUBMED   26805781
REFERENCE   2  (bases 1 to 1571)
  AUTHORS   Maynard TM, Meechan DW, Dudevoir ML, Gopalakrishna D, Peters AZ,
            Heindel CC, Sugimoto TJ, Wu Y, Lieberman JA and Lamantia AS.
  TITLE     Mitochondrial localization and function of a subset of 22q11
            deletion syndrome candidate genes
  JOURNAL   Mol Cell Neurosci 39 (3), 439-451 (2008)
   PUBMED   18775783
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473999.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_341010.3, XM_001063969.1.
            
            ##Evidence-Data-START##
            CDS exon combination :: FQ214161.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMD00132261, SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1571
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q23"
     gene            1..1571
                     /gene="Tango2"
                     /gene_synonym="RGD1310348"
                     /note="transport and golgi organization 2 homolog"
                     /db_xref="GeneID:360738"
                     /db_xref="RGD:1310348"
     exon            1..93
                     /gene="Tango2"
                     /gene_synonym="RGD1310348"
                     /inference="alignment:Splign:2.1.0"
     exon            94..187
                     /gene="Tango2"
                     /gene_synonym="RGD1310348"
                     /inference="alignment:Splign:2.1.0"
     CDS             132..962
                     /gene="Tango2"
                     /gene_synonym="RGD1310348"
                     /codon_start=1
                     /product="transport and Golgi organization protein 2
                     homolog"
                     /protein_id="NP_001101793.1"
                     /db_xref="GeneID:360738"
                     /db_xref="RGD:1310348"
                     /translation="MCIIFFKFDPRPVSKNAYRLILAANRDESYHRPSKLADFWENNS
                     EILSGLDMEEGKAGGTWLGISTRGKLGALTNYLQPRQEPDARGRGELVSHFLTSDMDS
                     LSYLKKVSTEGHLYNGFNLIAADLSTAKGDVVCYYGNRGEPEPIVLTPGTYGLSNALL
                     ETPWKKLCFGKQLFTEAVERSESLPKDILVTQLLEVLNNEEAQLPDPAIEDQGQEYIQ
                     PILSKYAAVCVRSATYGTRTNTIILVDADGHVTFTERSMLDKDTSCWETNTYEFTLQS
                     "
     exon            188..276
                     /gene="Tango2"
                     /gene_synonym="RGD1310348"
                     /inference="alignment:Splign:2.1.0"
     exon            277..396
                     /gene="Tango2"
                     /gene_synonym="RGD1310348"
                     /inference="alignment:Splign:2.1.0"
     exon            397..511
                     /gene="Tango2"
                     /gene_synonym="RGD1310348"
                     /inference="alignment:Splign:2.1.0"
     exon            512..582
                     /gene="Tango2"
                     /gene_synonym="RGD1310348"
                     /inference="alignment:Splign:2.1.0"
     exon            583..736
                     /gene="Tango2"
                     /gene_synonym="RGD1310348"
                     /inference="alignment:Splign:2.1.0"
     exon            737..841
                     /gene="Tango2"
                     /gene_synonym="RGD1310348"
                     /inference="alignment:Splign:2.1.0"
     exon            842..1571
                     /gene="Tango2"
                     /gene_synonym="RGD1310348"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgagcggcg ggtggctggg gctagcagtc tgcgctcctg gcggggctga cccacggtcg
       61 ggctccgggc tcttggaacg cggtctggac cagacctcgt gaccgtgcga gcaaagccac
      121 ccctgcaacc catgtgcatc atcttcttta agttcgatcc tcgtcccgtt tccaaaaatg
      181 cgtacaggct catcctggca gccaacagag atgaatccta ccacaggccg tccaagttgg
      241 cagacttctg ggagaacaac agcgagatcc tcagtgggct cgacatggaa gaaggcaagg
      301 caggaggaac atggctgggc atcagcacac gcgggaagct gggggcactc accaactacc
      361 tacagccccg gcaagagcca gacgcccgcg gcagaggtga acttgtgtct cactttctga
      421 ccagtgacat ggacagcctg tcctacctga agaaggtctc tacagagggg cacctataca
      481 acggctttaa cctcatagca gctgacctaa gcacagcaaa aggagatgtt gtttgctact
      541 atggaaaccg gggggagcct gagcctattg tcttgacacc aggaacctat gggctaagca
      601 atgccctgct ggagacgccc tggaagaagc tgtgctttgg caagcaactc ttcacggaag
      661 cagtggagcg gagcgagtca ctccctaagg acattcttgt cacccagctc ctagaagtcc
      721 tcaacaatga ggaggcacag ctgccagacc cagccattga ggaccagggc caggagtata
      781 ttcagccaat actgagcaag tatgcagctg tgtgtgtccg ctctgccacc tatggcacca
      841 gaaccaacac catcatcctt gtggatgcag atggccatgt gaccttcaca gaacgaagca
      901 tgctggacaa agacacctcc tgctgggaga ccaacaccta tgagttcaca ctacagagtt
      961 agtcactgcc aggctcctaa gggccagcat ggacaggaac ctttggtggc caccctgcat
     1021 gtctggctca gccagcatcc ctaggaccag gtccttctga tctgtgtcct cgtattcagc
     1081 tcagggtttg tctttgtacc aatggagaat ggcagagtca aatactaggt ctgagttggg
     1141 cctaggtgta tcctatgtga acacacgtac cttggtcagc cccaccacta ctgtgtacac
     1201 agacacgtgc accttactga tgagcagggt tatgcctctc acctcacatg tttggcaagt
     1261 gggtctcttc ttccctggac aggtaacaaa agcagacttt tttttttttt ttagaaactg
     1321 gagaccctgt atttgtttgc gttcagtagt tccgtatgca caaggactct gtgtgcattt
     1381 gctcaatgct gaggtgtgga acctgggatc tcttaggccc ctgcttgccc aggactgtgg
     1441 gttctgagca agaccatttc accaaatggc tcacgcagcc cctgccgtct ctcactgtcc
     1501 gtgttataag ctgtacacca tgggatgtga actcgaatgt gcacagttga taataaaact
     1561 ttgaggctgg a
//
