LOCUS       NM_001108642            1190 bp    mRNA    linear   ROD 19-SEP-2024
DEFINITION  Rattus norvegicus TAM41 mitochondrial translocator assembly and
            maintenance homolog (Tamm41), mRNA; nuclear gene for mitochondrial
            product.
ACCESSION   NM_001108642 XM_001053478 XM_001056640
VERSION     NM_001108642.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1190)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 1190)
  AUTHORS   Blunsom,N.J., Gomez-Espinosa,E., Ashlin,T.G. and Cockcroft,S.
  TITLE     Mitochondrial CDP-diacylglycerol synthase activity is due to the
            peripheral protein, TAMM41 and not due to the integral membrane
            protein, CDP-diacylglycerol synthase 1
  JOURNAL   Biochim Biophys Acta Mol Cell Biol Lipids 1863 (3), 284-298 (2018)
   PUBMED   29253589
  REMARK    GeneRIF: CDS activity present in mitochondria is mainly due to
            TAMM41, which is required for normal mitochondrial function.
REFERENCE   3  (bases 1 to 1190)
  AUTHORS   Ren,M., Phoon,C.K. and Schlame,M.
  TITLE     Metabolism and function of mitochondrial cardiolipin
  JOURNAL   Prog Lipid Res 55, 1-16 (2014)
   PUBMED   24769127
  REMARK    Review article
REFERENCE   4  (bases 1 to 1190)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473964.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001053478.1, XM_001056640.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ213922.1, SRR8487230.134430.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1190
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..1190
                     /gene="Tamm41"
                     /gene_synonym="TAM41"
                     /note="TAM41 mitochondrial translocator assembly and
                     maintenance homolog"
                     /db_xref="GeneID:362419"
                     /db_xref="RGD:1586150"
     exon            1..226
                     /gene="Tamm41"
                     /gene_synonym="TAM41"
                     /inference="alignment:Splign:2.1.0"
     CDS             92..1105
                     /gene="Tamm41"
                     /gene_synonym="TAM41"
                     /EC_number="2.7.7.41"
                     /note="MMP37-like protein, mitochondrial; mitochondrial
                     translocator assembly and maintenance protein 41 homolog;
                     TAM41, mitochondrial translocator assembly and maintenance
                     protein, homolog; CDP-DAG synthase; CDP-diacylglycerol
                     synthase"
                     /codon_start=1
                     /product="phosphatidate cytidylyltransferase,
                     mitochondrial"
                     /protein_id="NP_001102112.1"
                     /db_xref="GeneID:362419"
                     /db_xref="RGD:1586150"
                     /translation="MALQALHSSGVGLRRILAHFPEDLSLAFAYGSAVYRQAGPSAHQ
                     ENPMLDLVFTVDDPVAWHAMNLKKNWSHYSLLKLLGPRIISSVQNNYGAGVYFNPLIM
                     CDGKLIKYGVISTGTLIEDLLNWNNLYIAGRLQKPVKIVSMNESTVLRAALDKNLKSA
                     VTTACLMLPESFSEEDLFIEIAGLSYSGDFRMVIGEEKAKVLNIVKPNVVHFRELYES
                     ILQKDPQMVYKMHQGQLEIDKSPEGQFTQLMTLPRTLQQHINHIMDPPGRNRDVEETL
                     LQVAQDPDCGDVVRLAVSSIVRPSSIRQSTKGLFTAGVKKSVIYSSRKLNKMWKGWVR
                     KTS"
     exon            227..409
                     /gene="Tamm41"
                     /gene_synonym="TAM41"
                     /inference="alignment:Splign:2.1.0"
     exon            410..502
                     /gene="Tamm41"
                     /gene_synonym="TAM41"
                     /inference="alignment:Splign:2.1.0"
     exon            503..653
                     /gene="Tamm41"
                     /gene_synonym="TAM41"
                     /inference="alignment:Splign:2.1.0"
     exon            654..799
                     /gene="Tamm41"
                     /gene_synonym="TAM41"
                     /inference="alignment:Splign:2.1.0"
     exon            800..965
                     /gene="Tamm41"
                     /gene_synonym="TAM41"
                     /inference="alignment:Splign:2.1.0"
     exon            966..1028
                     /gene="Tamm41"
                     /gene_synonym="TAM41"
                     /inference="alignment:Splign:2.1.0"
     exon            1029..1190
                     /gene="Tamm41"
                     /gene_synonym="TAM41"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggccgggcg gaagcgcggt ccgcacgacc gagaattgcg agcacagggt ccgcacagca
       61 ccctctgtcc tactggcggg ccagcccgcc catggcgctg caggcgctgc acagctcggg
      121 cgtgggcctg cgcaggattc tggctcactt cccggaggac ctgagtttgg ccttcgccta
      181 cggctctgcg gtgtatcgcc aggcaggacc cagtgcacac caggagaatc ccatgttaga
      241 tctagtgttc acagtagatg accctgttgc ctggcatgca atgaacctga agaagaactg
      301 gagccactac tctctcctca aactcttggg gcccaggatc atctcatccg tccagaataa
      361 ttatggtgcc ggcgtctact tcaacccact gatcatgtgt gacgggaagc ttatcaaata
      421 tggggtcatt agcactggca ctctgattga ggacctcctg aactggaata acctatatat
      481 cgccggacgt ctccaaaagc cggtgaagat tgtatcgatg aatgagagca cagttcttag
      541 agctgccctg gataaaaacc tgaagagtgc ggtgaccacc gcctgcctca tgctacccga
      601 aagcttctct gaggaagacc tattcataga gattgctggg ctctcctact caggtgactt
      661 ccgaatggtg attggagaag agaaagccaa agtgttgaac atcgtgaagc ccaacgtagt
      721 ccatttccga gagctctatg agagcatatt acagaaggac cctcagatgg tgtataagat
      781 gcatcagggc caactggaga tagataaaag cccagaagga cagttcactc agctaatgac
      841 attgcctaga acgttacagc agcatatcaa tcacatcatg gaccctcctg ggagaaacag
      901 ggatgtggaa gagactttac tgcaagtggc tcaggacccc gactgtggtg acgtggtacg
      961 actagcggtc tcttcaatcg tcagaccttc cagcatcagg cagagcacca aaggcctttt
     1021 tactgctggt gtgaagaagt ctgtgattta tagttcacgg aaactgaaca aaatgtggaa
     1081 agggtgggtg agaaaaacat cctgacttga ctgatgtgtt acgggtagat tatgaataaa
     1141 tggctccatg ctttttgaca agagttgctt gtcactctgg ctgactgctt
//
