LOCUS       NM_031676               1047 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus transgelin 3 (Tagln3), transcript variant 2,
            mRNA.
ACCESSION   NM_031676
VERSION     NM_031676.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1047)
  AUTHORS   Feng,J., Lawson,M.A. and Melamed,P.
  TITLE     A proteomic comparison of immature and mature mouse gonadotrophs
            reveals novel differentially expressed nuclear proteins that
            regulate gonadotropin gene transcription and RNA splicing
  JOURNAL   Biol Reprod 79 (3), 546-561 (2008)
   PUBMED   18480465
REFERENCE   2  (bases 1 to 1047)
  AUTHORS   Werner,H.B., Kuhlmann,K., Shen,S., Uecker,M., Schardt,A.,
            Dimova,K., Orfaniotou,F., Dhaunchak,A., Brinkmann,B.G., Mobius,W.,
            Guarente,L., Casaccia-Bonnefil,P., Jahn,O. and Nave,K.A.
  TITLE     Proteolipid protein is required for transport of sirtuin 2 into CNS
            myelin
  JOURNAL   J Neurosci 27 (29), 7717-7730 (2007)
   PUBMED   17634366
REFERENCE   3  (bases 1 to 1047)
  AUTHORS   Depaz,I.M. and Wilce,P.A.
  TITLE     The novel cytoskeleton-associated protein Neuronal protein 22:
            elevated expression in the developing rat brain
  JOURNAL   Brain Res 1081 (1), 59-64 (2006)
   PUBMED   16542643
  REMARK    GeneRIF: NP22 may play a role in mediating the molecular events
            governing development of the neuronal architecture. Furthermore,
            its sustained expression in postnatal brain implies a function in
            the maintenance of neuronal morphology.
REFERENCE   4  (bases 1 to 1047)
  AUTHORS   Fan,L., Jaquet,V., Dodd,P.R., Chen,W. and Wilce,P.A.
  TITLE     Molecular cloning and characterization of hNP22: a gene
            up-regulated in human alcoholic brain
  JOURNAL   J Neurochem 76 (5), 1275-1281 (2001)
   PUBMED   11238712
REFERENCE   5  (bases 1 to 1047)
  AUTHORS   Ren,W.Z., Ng,G.Y., Wang,R.X., Wu,P.H., O'Dowd,B.F., Osmond,D.H.,
            George,S.R. and Liew,C.C.
  TITLE     The identification of NP25: a novel protein that is differentially
            expressed by neuronal subpopulations
  JOURNAL   Brain Res Mol Brain Res 22 (1-4), 173-185 (1994)
   PUBMED   8015377
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB795348.1, AF459788.1 and M84725.1.
            
            On Oct 28, 2005 this sequence version replaced NM_031676.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ212759.1, FQ212858.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-339               CB795348.1         42-380
            340-724             AF459788.1         536-920
            725-1047            M84725.1           698-1020
FEATURES             Location/Qualifiers
     source          1..1047
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q21"
     gene            1..1047
                     /gene="Tagln3"
                     /gene_synonym="Np22; Np25"
                     /note="transgelin 3"
                     /db_xref="GeneID:63837"
                     /db_xref="RGD:69301"
     exon            1..274
                     /gene="Tagln3"
                     /gene_synonym="Np22; Np25"
                     /inference="alignment:Splign:2.1.0"
     CDS             95..694
                     /gene="Tagln3"
                     /gene_synonym="Np22; Np25"
                     /note="neuronal protein 22; neuronal protein Np25"
                     /codon_start=1
                     /product="transgelin-3"
                     /protein_id="NP_113864.2"
                     /db_xref="GeneID:63837"
                     /db_xref="RGD:69301"
                     /translation="MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEH
                     PPPGRTHFQKWLMDGTVLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAEV
                     YGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRR
                     GFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPRQIM"
     exon            275..449
                     /gene="Tagln3"
                     /gene_synonym="Np22; Np25"
                     /inference="alignment:Splign:2.1.0"
     exon            450..552
                     /gene="Tagln3"
                     /gene_synonym="Np22; Np25"
                     /inference="alignment:Splign:2.1.0"
     exon            553..1033
                     /gene="Tagln3"
                     /gene_synonym="Np22; Np25"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1034
                     /gene="Tagln3"
                     /gene_synonym="Np22; Np25"
ORIGIN      
        1 cctgccacat cccagccggg ttctcaggaa acccgggggc tcctgtggct gctattgtgt
       61 ggatgccgcg cgtgtcctct cttctcttcc agagatggct aacaggggtc cgagctacgg
      121 cttaagccga gaggtgcagg agaagattga gcagaaatat gacgcggacc tggagaacaa
      181 gctggtggac tggatcatcc tgcagtgtgc tgaggatata gagcacccgc ccccgggcag
      241 gacccatttt cagaaatggt tgatggacgg gacggtcctg tgcaagctga taaacagttt
      301 atatccacca ggacaagaac ccatccccaa gatctcagag tcaaagatgg cttttaagca
      361 gatggagcaa atctctcagt tcctgaaggc tgccgaggtc tatggcgtca ggaccactga
      421 catttttcaa acagtggatc tatgggaagg gaaggacatg gcagctgtgc agaggactct
      481 gatggctctg ggaagcgttg cagttaccaa ggatgatggc tgctaccggg gagagccgtc
      541 ctggtttcac aggaaagccc agcagaatcg gagaggattt tcagaggagc aacttcgcca
      601 gggacagaat gtcataggcc tgcagatggg cagcaacaag ggtgcctccc aggcaggcat
      661 gacggggtac gggatgccca ggcagatcat gtaagatgtt gtatagtgag tgccccctgg
      721 tagagaggac ggatgttccg caccacagtc tgtgacaaag aattaggtag tcaccttctc
      781 accttctctt tctcaaagcc ttctgtcccc tgttcttgca aagtgctgca cttctgctga
      841 gaatccacgc tgcctactgc tgcctactgc tgccaccttc tgttccttta gaactatgca
      901 aagactgccc ttcctctcgc tgacctcctg tgccctaaga tctcagtttg tttgattatt
      961 tatttattta tttgccaaaa aaaatttctc tccttgactt acagaacgta cctaataaac
     1021 aaattagtct gtgaaaaaaa aaaaaaa
//
