LOCUS       NM_001044225            2127 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Rattus norvegicus TATA-box binding protein associated factor 6
            (Taf6), mRNA.
ACCESSION   NM_001044225 XM_001056390 XM_001066592 XM_001066806 XM_213729
VERSION     NM_001044225.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2127)
  AUTHORS   Louder,R.K., He,Y., Lopez-Blanco,J.R., Fang,J., Chacon,P. and
            Nogales,E.
  TITLE     Structure of promoter-bound TFIID and model of human pre-initiation
            complex assembly
  JOURNAL   Nature 531 (7596), 604-609 (2016)
   PUBMED   27007846
  REMARK    Erratum:[Nature. 2016 Aug 4;536(7614):112. doi:
            10.1038/nature17984.. PMID: 27096372]
REFERENCE   2  (bases 1 to 2127)
  AUTHORS   Malkowska,M., Kokoszynska,K., Rychlewski,L. and Wyrwicz,L.
  TITLE     Structural bioinformatics of the general transcription factor TFIID
  JOURNAL   Biochimie 95 (4), 680-691 (2013)
   PUBMED   23146842
  REMARK    Review article
REFERENCE   3  (bases 1 to 2127)
  AUTHORS   Kamileri,I., Karakasilioti,I., Sideri,A., Kosteas,T., Tatarakis,A.,
            Talianidis,I. and Garinis,G.A.
  TITLE     Defective transcription initiation causes postnatal growth failure
            in a mouse model of nucleotide excision repair (NER) progeria
  JOURNAL   Proc Natl Acad Sci U S A 109 (8), 2995-3000 (2012)
   PUBMED   22323595
REFERENCE   4  (bases 1 to 2127)
  AUTHORS   Wilhelm,E., Kornete,M., Targat,B., Vigneault-Edwards,J.,
            Frontini,M., Tora,L., Benecke,A. and Bell,B.
  TITLE     TAF6delta orchestrates an apoptotic transcriptome profile and
            interacts functionally with p53
  JOURNAL   BMC Mol Biol 11, 10 (2010)
   PUBMED   20096117
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2127)
  AUTHORS   Tatarakis,A., Margaritis,T., Martinez-Jimenez,C.P., Kouskouti,A.,
            Mohan,W.S. 2nd, Haroniti,A., Kafetzopoulos,D., Tora,L. and
            Talianidis,I.
  TITLE     Dominant and redundant functions of TFIID involved in the
            regulation of hepatic genes
  JOURNAL   Mol Cell 31 (4), 531-543 (2008)
   PUBMED   18722179
REFERENCE   6  (bases 1 to 2127)
  AUTHORS   Pointud,J.C., Mengus,G., Brancorsini,S., Monaco,L., Parvinen,M.,
            Sassone-Corsi,P. and Davidson,I.
  TITLE     The intracellular localisation of TAF7L, a paralogue of
            transcription factor TFIID subunit TAF7, is developmentally
            regulated during male germ-cell differentiation
  JOURNAL   J Cell Sci 116 (Pt 9), 1847-1858 (2003)
   PUBMED   12665565
REFERENCE   7  (bases 1 to 2127)
  AUTHORS   Bell,B., Scheer,E. and Tora,L.
  TITLE     Identification of hTAF(II)80 delta links apoptotic signaling
            pathways to transcription factor TFIID function
  JOURNAL   Mol Cell 8 (3), 591-600 (2001)
   PUBMED   11583621
REFERENCE   8  (bases 1 to 2127)
  AUTHORS   Wieczorek,E., Brand,M., Jacq,X. and Tora,L.
  TITLE     Function of TAF(II)-containing complex without TBP in transcription
            by RNA polymerase II
  JOURNAL   Nature 393 (6681), 187-191 (1998)
   PUBMED   9603525
REFERENCE   9  (bases 1 to 2127)
  AUTHORS   Kida,S., Umehara,T. and Horikoshi,M.
  TITLE     Three distinct regions in a rat TFIID subunit containing histone H4
            homology
  JOURNAL   Gene 161 (2), 303-304 (1995)
   PUBMED   7665101
REFERENCE   10 (bases 1 to 2127)
  AUTHORS   Weinzierl,R.O., Ruppert,S., Dynlacht,B.D., Tanese,N. and Tjian,R.
  TITLE     Cloning and expression of Drosophila TAFII60 and human TAFII70
            reveal conserved interactions with other subunits of TFIID
  JOURNAL   EMBO J 12 (13), 5303-5309 (1993)
   PUBMED   8262073
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC100108.1.
            
            [WARNING] On Mar 13, 2025 this sequence was replaced by
            NM_001044225.2.
            
            On or before Aug 24, 2006 this sequence version replaced
            XM_213729.4, XM_001056390.1, XM_001066806.1, XM_001066592.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC100108.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760434
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2127
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q11"
     gene            1..2127
                     /gene="Taf6"
                     /gene_synonym="TAF(II)80; TAFII70"
                     /note="TATA-box binding protein associated factor 6"
                     /db_xref="GeneID:288533"
                     /db_xref="RGD:1311608"
     exon            1..36
                     /gene="Taf6"
                     /gene_synonym="TAF(II)80; TAFII70"
                     /inference="alignment:Splign:2.1.0"
     exon            37..252
                     /gene="Taf6"
                     /gene_synonym="TAF(II)80; TAFII70"
                     /inference="alignment:Splign:2.1.0"
     CDS             97..2040
                     /gene="Taf6"
                     /gene_synonym="TAF(II)80; TAFII70"
                     /note="TAF6 RNA polymerase II, TATA box binding protein
                     (TBP)-associated factor, 80 kDa; TFIID subunit p80;
                     TAFII80; TAFII-70; TAFII-80; TAF(II)70; transcription
                     initiation factor TFIID 70 kDa subunit; transcription
                     initiation factor TFIID 80 kDa subunit"
                     /codon_start=1
                     /product="transcription initiation factor TFIID subunit 6"
                     /protein_id="NP_001037690.1"
                     /db_xref="GeneID:288533"
                     /db_xref="RGD:1311608"
                     /translation="MAEEKKLKLSNTVLPSESMKVVAESMGIAQIQEETCQLLTDEVS
                     YRIKEIAQDALKFMHMGKRQKLTTSDIDYALKLKNVEPLYGFHAQEFIPFRFASGGGR
                     ELYFYEEKEVDLSDIINTPLPRVPLDVCLKAHWLSIEGCQPAIPENPPPAPKEQQKAE
                     ATEPLKSAKPGQEEDGPLKGKGQGAAAADGKGKEKKAPPLLEGAPFRLKPRSIHELSV
                     EQQLYYKEITEACVGSCEAKRAEALQSIATDPGLYQMLPRFSTFISEGVRVNVVQNNL
                     ALLIYLMRMVKALMDNPTLYLEKYVHELIPAVMTCIVSRQLCLRPDVDNHWALRDFAA
                     RLVAQICKHFSTTTNNIQSRITKTFTKSWVDEKTPWTTRYGSIAGLAELGHDVIKTLI
                     LPRLQQEGERIRSVLDGPVLSNIDRIGADHVQSLLLKHCAPVLAKLRPPPDNQDAYRG
                     EFGSLGPLLCSHVVKARAQAALQAQQVNRTTLTITQPRPTLTLSQAPQPGPRTPGLLK
                     VPGSIALPVQTLVSARAAAPPQPSPPPTKFIVMSSSSSASSTQQGKAKEALLLILLQS
                     HLHLLHHLHLGAVPSVGGSRKLGTAPLQLQGLQRLMAPSLLDLALPSLLCDIVTCADL
                     LSSADSYTHKQRVREEEERCFPQ"
     exon            253..339
                     /gene="Taf6"
                     /gene_synonym="TAF(II)80; TAFII70"
                     /inference="alignment:Splign:2.1.0"
     exon            340..493
                     /gene="Taf6"
                     /gene_synonym="TAF(II)80; TAFII70"
                     /inference="alignment:Splign:2.1.0"
     exon            494..550
                     /gene="Taf6"
                     /gene_synonym="TAF(II)80; TAFII70"
                     /inference="alignment:Splign:2.1.0"
     exon            551..670
                     /gene="Taf6"
                     /gene_synonym="TAF(II)80; TAFII70"
                     /inference="alignment:Splign:2.1.0"
     exon            671..816
                     /gene="Taf6"
                     /gene_synonym="TAF(II)80; TAFII70"
                     /inference="alignment:Splign:2.1.0"
     exon            817..894
                     /gene="Taf6"
                     /gene_synonym="TAF(II)80; TAFII70"
                     /inference="alignment:Splign:2.1.0"
     exon            895..996
                     /gene="Taf6"
                     /gene_synonym="TAF(II)80; TAFII70"
                     /inference="alignment:Splign:2.1.0"
     exon            997..1179
                     /gene="Taf6"
                     /gene_synonym="TAF(II)80; TAFII70"
                     /inference="alignment:Splign:2.1.0"
     exon            1180..1254
                     /gene="Taf6"
                     /gene_synonym="TAF(II)80; TAFII70"
                     /inference="alignment:Splign:2.1.0"
     exon            1255..1380
                     /gene="Taf6"
                     /gene_synonym="TAF(II)80; TAFII70"
                     /inference="alignment:Splign:2.1.0"
     exon            1381..1554
                     /gene="Taf6"
                     /gene_synonym="TAF(II)80; TAFII70"
                     /inference="alignment:Splign:2.1.0"
     exon            1555..1752
                     /gene="Taf6"
                     /gene_synonym="TAF(II)80; TAFII70"
                     /inference="alignment:Splign:2.1.0"
     exon            1753..2095
                     /gene="Taf6"
                     /gene_synonym="TAF(II)80; TAFII70"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcgccgagc gccgggtgag cggcgccttg gcagcggatc tccatctctc caccctgggg
       61 tgacatcctt ccagggacag gagctggaac tccagcatgg ctgaggagaa gaaactgaaa
      121 ctcagcaata ccgtgttgcc ctccgagtct atgaaggtgg tggcagaatc catgggcatt
      181 gctcagattc aggaggagac ttgccagcta ctgacagatg aggtcagcta ccgcatcaag
      241 gagattgccc aggatgcttt gaagttcatg cacatgggga aacgacagaa gctcactacc
      301 agtgacattg actatgcatt gaaattaaag aatgtggagc cactatatgg cttccatgct
      361 caggagttca tccctttccg gtttgcctct ggtgggggcc gggagctgta cttctatgaa
      421 gagaaggaag tggacctgag tgatatcatc aacacccctc tgcctcgggt gcctctggat
      481 gtctgcctca aagctcattg gctgagcatt gaaggctgcc agccagctat accagagaat
      541 ccacccccag ctcccaaaga gcagcagaag gccgaggcca cagaacccct gaagtcagca
      601 aagccaggcc aagaagaaga tggacccttg aaaggcaaag gtcaaggggc agctgcagct
      661 gatggcaaag gaaaagagaa gaaggcacct cccttgctgg aaggggcccc tttccgcctg
      721 aagccccgca gcatccatga gctgtccgtg gagcagcagc tgtactacaa ggagatcaca
      781 gaagcctgtg tgggatcctg tgaggccaag agagcggaag ctctgcagag cattgccaca
      841 gatcctggac tctatcagat gttaccacgg tttagtacct tcatctcaga gggggtccgt
      901 gtgaatgtgg ttcagaataa cctggccttg ctcatctact tgatgcgaat ggttaaggcc
      961 ctgatggaca accccacact gtatcttgag aaatatgtgc acgagctgat tcctgcagta
     1021 atgacctgca ttgtgagcag acagctgtgc ctgcggccag atgtggacaa tcactgggca
     1081 ctccgggatt ttgctgcccg tctagtggcc cagatctgta agcatttcag cacaaccacc
     1141 aacaacatcc aatcccgaat caccaagacc tttaccaaga gctgggtgga tgagaagact
     1201 ccatggacaa ctcgatatgg ctccattgca ggcctggcag agctggggca tgatgtgatt
     1261 aagaccctaa ttctgccaag gctgcagcag gaaggggagc ggatccgaag tgtcttggac
     1321 ggacctgttc tgagcaacat cgaccgtatc ggagcagacc atgttcagag ccttctcctg
     1381 aaacactgtg ccccagtatt ggcgaagctg cgccctccac ctgacaatca ggatgcctac
     1441 cggggagaat ttgggtccct tgggcccctt ctctgctccc atgtggtgaa ggccagggcc
     1501 caggccgctc ttcaagctca gcaggtcaac aggaccacac tcaccatcac acagcctcgg
     1561 cccacactga ccctctcaca ggcccctcag ccaggccctc gtacccctgg cttattgaag
     1621 gtccctggct ctattgcctt gcctgtccag acactggtgt ctgcaagagc tgctgcccct
     1681 cctcagcctt ctcctcctcc aacgaagttt attgtaatgt cctcatcttc cagtgcctca
     1741 tcaacccagc aggggaaggc aaaggaggcc ctccttctca tccttctcca gtcccacctt
     1801 catcttcttc accatctcca cttgggggca gtgccctctg tggggggaag caggaaactg
     1861 gggacagccc ccctccagct ccagggactc caaaggctaa tggctcccag cctactggac
     1921 ctagctctcc ccagcctgct ctgtgatatt gtcacatgtg ctgacctcct ctcttctgca
     1981 gattcctaca cacacaaaca acgtgtgagg gaggaagaag aaagatgttt tccccagtga
     2041 ctttcttttt agattctgta cagtaagttc ctcagaataa aagttggatt tgtaaaaaaa
     2101 aaaaaaaaaa aaaaaaaaaa aaaaaaa
//
