LOCUS       NM_001106365            3240 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus TATA-box binding protein associated factor 5
            (Taf5), mRNA.
ACCESSION   NM_001106365 XM_001069140 XM_219965
VERSION     NM_001106365.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3240)
  AUTHORS   Wu Y, Lin JC, Piluso LG, Dhahbi JM, Bobadilla S, Spindler SR and
            Liu X.
  TITLE     Phosphorylation of p53 by TAF1 inactivates p53-dependent
            transcription in the DNA damage response
  JOURNAL   Mol Cell 53 (1), 63-74 (2014)
   PUBMED   24289924
REFERENCE   2  (bases 1 to 3240)
  AUTHORS   Malkowska M, Kokoszynska K, Rychlewski L and Wyrwicz L.
  TITLE     Structural bioinformatics of the general transcription factor TFIID
  JOURNAL   Biochimie 95 (4), 680-691 (2013)
   PUBMED   23146842
  REMARK    Review article
REFERENCE   3  (bases 1 to 3240)
  AUTHORS   Kamileri I, Karakasilioti I, Sideri A, Kosteas T, Tatarakis A,
            Talianidis I and Garinis GA.
  TITLE     Defective transcription initiation causes postnatal growth failure
            in a mouse model of nucleotide excision repair (NER) progeria
  JOURNAL   Proc Natl Acad Sci U S A 109 (8), 2995-3000 (2012)
   PUBMED   22323595
REFERENCE   4  (bases 1 to 3240)
  AUTHORS   Tatarakis A, Margaritis T, Martinez-Jimenez CP, Kouskouti A, Mohan
            WS 2nd, Haroniti A, Kafetzopoulos D, Tora L and Talianidis I.
  TITLE     Dominant and redundant functions of TFIID involved in the
            regulation of hepatic genes
  JOURNAL   Mol Cell 31 (4), 531-543 (2008)
   PUBMED   18722179
REFERENCE   5  (bases 1 to 3240)
  AUTHORS   Li AG, Piluso LG, Cai X, Gadd BJ, Ladurner AG and Liu X.
  TITLE     An acetylation switch in p53 mediates holo-TFIID recruitment
  JOURNAL   Mol Cell 28 (3), 408-421 (2007)
   PUBMED   17996705
REFERENCE   6  (bases 1 to 3240)
  AUTHORS   Boyer-Guittaut M, Birsoy K, Potel C, Elliott G, Jaffray E, Desterro
            JM, Hay RT and Oelgeschlager T.
  TITLE     SUMO-1 modification of human transcription factor (TF) IID complex
            subunits: inhibition of TFIID promoter-binding activity through
            SUMO-1 modification of hsTAF5
  JOURNAL   J Biol Chem 280 (11), 9937-9945 (2005)
   PUBMED   15637059
REFERENCE   7  (bases 1 to 3240)
  AUTHORS   Guermah M, Ge K, Chiang CM and Roeder RG.
  TITLE     The TBN protein, which is essential for early embryonic mouse
            development, is an inducible TAFII implicated in adipogenesis
  JOURNAL   Mol Cell 12 (4), 991-1001 (2003)
   PUBMED   14580349
REFERENCE   8  (bases 1 to 3240)
  AUTHORS   Brand M, Yamamoto K, Staub A and Tora L.
  TITLE     Identification of TATA-binding protein-free TAFII-containing
            complex subunits suggests a role in nucleosome acetylation and
            signal transduction
  JOURNAL   J Biol Chem 274 (26), 18285-18289 (1999)
   PUBMED   10373431
REFERENCE   9  (bases 1 to 3240)
  AUTHORS   Wieczorek E, Brand M, Jacq X and Tora L.
  TITLE     Function of TAF(II)-containing complex without TBP in transcription
            by RNA polymerase II
  JOURNAL   Nature 393 (6681), 187-191 (1998)
   PUBMED   9603525
REFERENCE   10 (bases 1 to 3240)
  AUTHORS   Tao Y, Guermah M, Martinez E, Oelgeschlager T, Hasegawa S, Takada
            R, Yamamoto T, Horikoshi M and Roeder RG.
  TITLE     Specific interactions and potential functions of human TAFII100
  JOURNAL   J Biol Chem 272 (10), 6714-6721 (1997)
   PUBMED   9045704
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473986.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001069140.1, XM_219965.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132262,
                              SAMD00132265 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3240
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q54"
     gene            1..3240
                     /gene="Taf5"
                     /note="TATA-box binding protein associated factor 5"
                     /db_xref="GeneID:294018"
                     /db_xref="RGD:1311332"
     exon            1..575
                     /gene="Taf5"
                     /inference="alignment:Splign:2.1.0"
     CDS             23..2419
                     /gene="Taf5"
                     /note="TAF5 RNA polymerase II, TATA box binding protein
                     (TBP)-associated factor"
                     /codon_start=1
                     /product="transcription initiation factor TFIID subunit 5"
                     /protein_id="NP_001099835.1"
                     /db_xref="GeneID:294018"
                     /db_xref="RGD:1311332"
                     /translation="MAALAEEQTEVAVKLESEGPPTLLPPQAGDGAGEGSGGTPNNGP
                     NGGGGNVAAAAGGDGGTPKPVVAVSAAAPAGAAPVPAAPAEAGAPHDRQTLLAVLQFL
                     RQSNLREAEEALRREARLLEEAVAGSGAPGELDGAGAEAASALLSRVTASVPGSAAPD
                     TPGAGASVTSVFSGSASGPAAPGKVASVAVEDQPDVSAVLSAYNQQGDPTMYEEYYSG
                     LKHFIECSLDCHRAELSQLFYPLFVHMYLELVYNQHESEAKSFFEKFHGDQECYYQDD
                     LRVLSSLTKKEHMKGNETMLDFRTSKFVLRISRDSYQLLKRHLQEKQNNQIWNIVQEH
                     LYIDIFDGMPRSKQQIDAMVGSLAGEAKREANKSKVFFGLLKEPEIEVPLDDEDEEGE
                     NEEGKPKKKKPKKDSIGSKSKKQDPNAPPQNRIPLPELKDSDKLDKIMNMKETTKRVR
                     LGPDCLPSICFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQA
                     SDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVR
                     LWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGH
                     LADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFL
                     ATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIK
                     AFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPVVHLHFTRRNLVLAAGAYSPQ
                     "
     exon            576..813
                     /gene="Taf5"
                     /inference="alignment:Splign:2.1.0"
     exon            814..1129
                     /gene="Taf5"
                     /inference="alignment:Splign:2.1.0"
     exon            1130..1293
                     /gene="Taf5"
                     /inference="alignment:Splign:2.1.0"
     exon            1294..1429
                     /gene="Taf5"
                     /inference="alignment:Splign:2.1.0"
     exon            1430..1550
                     /gene="Taf5"
                     /inference="alignment:Splign:2.1.0"
     exon            1551..1680
                     /gene="Taf5"
                     /inference="alignment:Splign:2.1.0"
     exon            1681..1845
                     /gene="Taf5"
                     /inference="alignment:Splign:2.1.0"
     exon            1846..2023
                     /gene="Taf5"
                     /inference="alignment:Splign:2.1.0"
     exon            2024..2201
                     /gene="Taf5"
                     /inference="alignment:Splign:2.1.0"
     exon            2202..3240
                     /gene="Taf5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcgaggtgg ctcagccgca agatggcggc gctggcggag gagcagacgg aggtggcggt
       61 caagctagag tctgagggac cgccaacgct gctacctccg caggctggcg acggcgcagg
      121 cgagggtagc ggtggcactc ctaacaacgg ccccaacggc ggcggcggga atgtggcggc
      181 ggcggccggt ggggacggcg ggacccccaa accagtggtg gctgtttctg ccgctgcccc
      241 ggcgggggcg gccccggtgc ccgccgctcc cgcggaggcc ggcgctcctc acgaccgaca
      301 gactcttctg gctgtgctgc agttcctacg gcagagcaac ctccgcgagg ccgaagaggc
      361 actgcgccgt gaggcccggc tgctggagga ggcggtggcg ggctccggag ctccgggaga
      421 gttggacggg gctggcgcgg aggcggctag tgcgcttctc agccgggtca ccgcttcagt
      481 tcccggctct gcggcccccg acactccggg agccggcgct tcggtgacct cagtgttctc
      541 aggttcagcc tcaggtcctg cggctccggg aaaggttgca agtgtagctg tggaagacca
      601 gccagatgtc agtgctgtct tgtcggccta caaccaacaa ggagacccta caatgtatga
      661 agaatactac agtggactga aacacttcat tgaatgttct ctggactgcc atcgagcaga
      721 attatcccaa ctcttttatc ctctgtttgt acatatgtac ttggagctag tttataatca
      781 acatgaaagt gaagcaaaat cattctttga gaagttccac ggagatcagg aatgttatta
      841 ccaggatgac ctacgagtat tatctagtct taccaaaaag gagcacatga aagggaatga
      901 gaccatgctg gactttcgga caagtaaatt tgttcttcgc atttcccgtg actcgtacca
      961 actcttgaag cggcatcttc aggagaaaca gaacaatcag atatggaaca tagttcagga
     1021 gcacctctac atcgacatct ttgacgggat gccccgcagt aagcagcaga tagacgccat
     1081 ggtgggaagc ctggcaggcg aggctaagcg agaagcaaac aaatcaaagg tattttttgg
     1141 tttattaaaa gaaccggaaa ttgaggtgcc tttggatgat gaggatgaag aaggagaaaa
     1201 cgaagagggg aaacctaaaa agaagaagcc taaaaaggat agtattggct ctaaaagcaa
     1261 gaaacaagat cccaatgctc caccccaaaa cagaatcccc cttcccgagt tgaaagattc
     1321 agacaaactg gacaaaataa tgaatatgaa ggaaactacc aaacgagtgc gccttgggcc
     1381 tgactgttta ccctccattt gtttctatac attccttaat gcgtaccagg gcctcactgc
     1441 agtggatgtc actgatgatt ctagcctgat tgctggaggt tttgctgatt caaccgtcag
     1501 agtgtggtct gtgaccccta aaaagcttcg tagtgtcaaa caagcatcag atcttagtct
     1561 tatagacaaa gaatcagatg atgtcttaga gagaatcatg gatgagaaaa ctgcaagtga
     1621 gttgaagatt ttgtatggtc acagtgggcc tgtctatgga gccagcttca gtccggatag
     1681 gaactaccta ctctcctctt cagaggatgg aaccgttaga ctctggagcc tgcagacttt
     1741 cacttgctta gttggatata aagggcacaa ctacccagtg tgggacacac agttttctcc
     1801 atatggatat tatttcgtgt caggaggcca tgaccgcgta gctcggcttt gggctacaga
     1861 tcactatcag cctttaagga tattcgctgg ccatcttgct gatgtgaatt gcactagatt
     1921 tcatccaaat tccaactatg ttgctacggg ctctgcagac agaaccgtgc ggctctggga
     1981 cgtcctcaat ggtaactgtg taaggatctt cactggacac aagggaccaa ttcattcctt
     2041 gacattttct cccaatggga gattcctggc tacaggagca acagatggca gagtacttct
     2101 ttgggatatc ggacatggct tgatggttgg agaattaaaa ggccacactg atacagtgtg
     2161 ttcacttagg tttagtagag atggtgagat tttggcatca ggttcgatgg ataacacagt
     2221 tcggttatgg gatgccatca aagcatttga agatttagaa actgatgact ttactacagc
     2281 cactgggcat ataaatctac ctgagaattc ccaggagtta ctgttgggta catacatgac
     2341 caaatcaaca ccagtcgtac acctacattt tacaagaaga aacttggttc tagctgcagg
     2401 agcttacagt ccgcaataaa ccaacggtat tagagacctt ttggaagcta ctgtttggaa
     2461 aagggagact aaaagcaaat acctcagtga ttagtattta agctacaaag aatgtttttg
     2521 tctacatgga tctggaagta tgctgcttgg aaaatctgaa caggacagtt ccacgtttct
     2581 atagcaacca catttaacta atttccgtta gttgaataag aggtattatg ttcgtggaga
     2641 ggacattatg gtgctttgga ttgtgtggaa actatgcatt tttttgttca aatgctattt
     2701 taatttatta tgtctagaaa aaaaatcaat ttgatttaaa caattcattc tgcttcaaga
     2761 ttcaagttaa gaaatatagt accatcttga gtagctgaag agttctatga gcatgtgtgt
     2821 gtctgctgta aatgacgtta ttgtacggca ctcaagcagt gtgttaaatg accactaaca
     2881 tgcttttctt cgcccgtgat tagcgggctg tatgtaactg ggtaggagat cacatttcct
     2941 aagacctaga tgtataacca cccacaacat ctcagctcct actgtgtaag tttggagtgc
     3001 aatcaaacac ttagaaaaca ggtgaagagg tttagattcc attctacttc agctaacgtg
     3061 gctacatatg acctagtaca cttgaagtca gacagacatt tcagttgctt acctccagta
     3121 ctgagccttg ctttggaaaa ctaagagatt tagaccaagt cactgccagt ttttgccttt
     3181 gttgcatttt gtacagtttt atatttttga tatcttgtaa ataaagacaa ccagcttttc
//
