LOCUS       NM_001402170            4438 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus TATA-box binding protein associated factor 4
            (Taf4), mRNA.
ACCESSION   NM_001402170 XR_591920
VERSION     NM_001402170.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4438)
  AUTHORS   Wu,Y., Lin,J.C., Piluso,L.G., Dhahbi,J.M., Bobadilla,S.,
            Spindler,S.R. and Liu,X.
  TITLE     Phosphorylation of p53 by TAF1 inactivates p53-dependent
            transcription in the DNA damage response
  JOURNAL   Mol Cell 53 (1), 63-74 (2014)
   PUBMED   24289924
REFERENCE   2  (bases 1 to 4438)
  AUTHORS   Malkowska,M., Kokoszynska,K., Rychlewski,L. and Wyrwicz,L.
  TITLE     Structural bioinformatics of the general transcription factor TFIID
  JOURNAL   Biochimie 95 (4), 680-691 (2013)
   PUBMED   23146842
  REMARK    Review article
REFERENCE   3  (bases 1 to 4438)
  AUTHORS   Kamileri,I., Karakasilioti,I., Sideri,A., Kosteas,T., Tatarakis,A.,
            Talianidis,I. and Garinis,G.A.
  TITLE     Defective transcription initiation causes postnatal growth failure
            in a mouse model of nucleotide excision repair (NER) progeria
  JOURNAL   Proc Natl Acad Sci U S A 109 (8), 2995-3000 (2012)
   PUBMED   22323595
REFERENCE   4  (bases 1 to 4438)
  AUTHORS   Tatarakis,A., Margaritis,T., Martinez-Jimenez,C.P., Kouskouti,A.,
            Mohan,W.S. 2nd, Haroniti,A., Kafetzopoulos,D., Tora,L. and
            Talianidis,I.
  TITLE     Dominant and redundant functions of TFIID involved in the
            regulation of hepatic genes
  JOURNAL   Mol Cell 31 (4), 531-543 (2008)
   PUBMED   18722179
REFERENCE   5  (bases 1 to 4438)
  AUTHORS   Dou,Y., Milne,T.A., Tackett,A.J., Smith,E.R., Fukuda,A.,
            Wysocka,J., Allis,C.D., Chait,B.T., Hess,J.L. and Roeder,R.G.
  TITLE     Physical association and coordinate function of the H3 K4
            methyltransferase MLL1 and the H4 K16 acetyltransferase MOF
  JOURNAL   Cell 121 (6), 873-885 (2005)
   PUBMED   15960975
REFERENCE   6  (bases 1 to 4438)
  AUTHORS   Pointud,J.C., Mengus,G., Brancorsini,S., Monaco,L., Parvinen,M.,
            Sassone-Corsi,P. and Davidson,I.
  TITLE     The intracellular localisation of TAF7L, a paralogue of
            transcription factor TFIID subunit TAF7, is developmentally
            regulated during male germ-cell differentiation
  JOURNAL   J Cell Sci 116 (Pt 9), 1847-1858 (2003)
   PUBMED   12665565
REFERENCE   7  (bases 1 to 4438)
  AUTHORS   Metsis,M., Brunkhorst,A. and Neuman,T.
  TITLE     Cell-type-specific expression of the TFIID component TAF(II)135 in
            the nervous system
  JOURNAL   Exp Cell Res 269 (2), 214-221 (2001)
   PUBMED   11570813
REFERENCE   8  (bases 1 to 4438)
  AUTHORS   Freiman,R.N., Albright,S.R., Zheng,S., Sha,W.C., Hammer,R.E. and
            Tjian,R.
  TITLE     Requirement of tissue-selective TBP-associated factor TAFII105 in
            ovarian development
  JOURNAL   Science 293 (5537), 2084-2087 (2001)
   PUBMED   11557891
REFERENCE   9  (bases 1 to 4438)
  AUTHORS   Brand,M., Yamamoto,K., Staub,A. and Tora,L.
  TITLE     Identification of TATA-binding protein-free TAFII-containing
            complex subunits suggests a role in nucleosome acetylation and
            signal transduction
  JOURNAL   J Biol Chem 274 (26), 18285-18289 (1999)
   PUBMED   10373431
REFERENCE   10 (bases 1 to 4438)
  AUTHORS   Wieczorek,E., Brand,M., Jacq,X. and Tora,L.
  TITLE     Function of TAF(II)-containing complex without TBP in transcription
            by RNA polymerase II
  JOURNAL   Nature 393 (6681), 187-191 (1998)
   PUBMED   9603525
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Mar 8, 2022 this sequence version replaced XR_591920.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643292.16006.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1036              JAXUCZ010000003.1  187460007-187461042 c
            1037-1285           JAXUCZ010000003.1  187459758-187460006 c
            1286-1446           JAXUCZ010000003.1  187422826-187422986 c
            1447-1566           JAXUCZ010000003.1  187421646-187421765 c
            1567-1686           JAXUCZ010000003.1  187419163-187419282 c
            1687-1809           JAXUCZ010000003.1  187418321-187418443 c
            1810-1899           JAXUCZ010000003.1  187416192-187416281 c
            1900-2145           JAXUCZ010000003.1  187415543-187415788 c
            2146-2293           JAXUCZ010000003.1  187412879-187413026 c
            2294-2408           JAXUCZ010000003.1  187409083-187409197 c
            2409-2578           JAXUCZ010000003.1  187407078-187407247 c
            2579-2709           JAXUCZ010000003.1  187406643-187406773 c
            2710-2835           JAXUCZ010000003.1  187405667-187405792 c
            2836-2892           JAXUCZ010000003.1  187404763-187404819 c
            2893-3012           JAXUCZ010000003.1  187404099-187404218 c
            3013-4438           JAXUCZ010000003.1  187395632-187397057 c
FEATURES             Location/Qualifiers
     source          1..4438
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q43"
     gene            1..4438
                     /gene="Taf4"
                     /gene_synonym="Taf4a"
                     /note="TATA-box binding protein associated factor 4"
                     /db_xref="GeneID:682097"
                     /db_xref="RGD:1588072"
     exon            1..1285
                     /gene="Taf4"
                     /gene_synonym="Taf4a"
                     /inference="alignment:Splign:2.1.0"
     CDS             58..3180
                     /gene="Taf4"
                     /gene_synonym="Taf4a"
                     /note="TAF4 RNA polymerase II, TATA box binding protein
                     (TBP)-associated factor, 135kDa"
                     /codon_start=1
                     /product="transcription initiation factor TFIID subunit 4"
                     /protein_id="NP_001389099.1"
                     /db_xref="GeneID:682097"
                     /db_xref="RGD:1588072"
                     /translation="MAAGSDLLDEVFFNSEVDEKVVSDLVGSLESQLAASAAHHHHLA
                     PRTPELRAAAAGALGNHVVSGSPAGAAGAGPAASAEGAPAAAPEPPPAGRARPAGGGP
                     RRPGSSSPRRLLVPAGPAPAPAKLRPPPEASAGPCPVAAAAATAAAAAGPDPAAAAPP
                     AGPGASKPGPPGPPGPGAAQTLNGSAAPPTAPHAAPAVSPVNNGPAPPPAAGSVIQAA
                     PAPAAPSPPAAPAPAAPPPPAPPAPVAPARPPGHPAAPAPPVSPAAAAAAAAAAAQNG
                     AAPAPAAASGGAAGLGQPGAGAQGAKAEAPKPGPGPGPGPAAAAAAAAGGVAGGGAAG
                     GVLLGPAMPGALPGPAPGTPAGLAKGAAAATPSLPRTPAATTGAIRATLTPTVLAPRL
                     PQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAHAQAQPQSTMAPRPAT
                     PTGAAPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPTTTLQRSPGVQPQLVL
                     GGSAQPASLGTATAVQTGTPQRTVTGASTTSTAATETMENVKKCKSFLSTLIKLASSG
                     KQSTETAANVKDLVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLT
                     PDSAAFIQQSQQQQPPASQATTALTAVVLSSSVQRTAGKTAASVTSALQPPVISLTQP
                     TQVGVGKQAPPTPLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTPQQIQL
                     NQLQPVPVVKPTVLPGTKALSTVSAQAAAAQKNKLKEPGGGSFRDDDDINDVASMAGV
                     NLSEESARILATNSELVGTLTRSCKDDTFLLPAPLQRRILEIGKKHGITELHPDVVSY
                     VSHATQQRLQNLVEKISETAQQKNFSYKDDDRYEQASDVRAQLKFFEQLDQIEKQRKD
                     EQEREILMRAAKSRSRQEDPEQLRLKQKAKEMQQQELAQMRQRDANLTALAAIGPRKK
                     RKVDCAGPGSGAEGSGPGAAVPGGSGVGTPRQFTRQRITRVNLRDLIFCLENERETSH
                     SLLLYKAFLK"
     exon            1286..1446
                     /gene="Taf4"
                     /gene_synonym="Taf4a"
                     /inference="alignment:Splign:2.1.0"
     exon            1447..1566
                     /gene="Taf4"
                     /gene_synonym="Taf4a"
                     /inference="alignment:Splign:2.1.0"
     exon            1567..1686
                     /gene="Taf4"
                     /gene_synonym="Taf4a"
                     /inference="alignment:Splign:2.1.0"
     exon            1687..1809
                     /gene="Taf4"
                     /gene_synonym="Taf4a"
                     /inference="alignment:Splign:2.1.0"
     exon            1810..1899
                     /gene="Taf4"
                     /gene_synonym="Taf4a"
                     /inference="alignment:Splign:2.1.0"
     exon            1900..2145
                     /gene="Taf4"
                     /gene_synonym="Taf4a"
                     /inference="alignment:Splign:2.1.0"
     exon            2146..2293
                     /gene="Taf4"
                     /gene_synonym="Taf4a"
                     /inference="alignment:Splign:2.1.0"
     exon            2294..2408
                     /gene="Taf4"
                     /gene_synonym="Taf4a"
                     /inference="alignment:Splign:2.1.0"
     exon            2409..2578
                     /gene="Taf4"
                     /gene_synonym="Taf4a"
                     /inference="alignment:Splign:2.1.0"
     exon            2579..2709
                     /gene="Taf4"
                     /gene_synonym="Taf4a"
                     /inference="alignment:Splign:2.1.0"
     exon            2710..2835
                     /gene="Taf4"
                     /gene_synonym="Taf4a"
                     /inference="alignment:Splign:2.1.0"
     exon            2836..2892
                     /gene="Taf4"
                     /gene_synonym="Taf4a"
                     /inference="alignment:Splign:2.1.0"
     exon            2893..3012
                     /gene="Taf4"
                     /gene_synonym="Taf4a"
                     /inference="alignment:Splign:2.1.0"
     exon            3013..4438
                     /gene="Taf4"
                     /gene_synonym="Taf4a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctcctgccc aggcgcgctc ggccgagcgg cggcggcggc ggcggcgagg aggaaagatg
       61 gcggcgggct cggatctgct ggacgaggtc ttcttcaaca gcgaggtgga cgagaaagtg
      121 gtgagcgatc tggtgggctc gctcgagtcg cagctggcgg ccagcgcggc ccaccaccac
      181 cacctcgcgc cgcgcacgcc cgagctgcgg gccgcggccg ccggcgcgct cgggaaccat
      241 gttgtgagcg gcagcccggc cggagccgcg ggcgcagggc cggccgcctc cgccgagggc
      301 gcgcccgcag cggcgccgga gccgcccccc gcaggtagag cgcggccggc gggtgggggc
      361 ccgcggcgcc cgggctccag ctcaccgcgc cgcttgcttg tccccgcagg gcccgcgccg
      421 gcgcccgcca agctgaggcc gccgcccgag gccagcgcgg ggccctgccc cgtcgccgcc
      481 gccgccgcca ccgctgccgc cgccgcgggg ccggatcccg ccgccgccgc cccgcccgcc
      541 ggccccggcg cctccaagcc cggcccgcct ggcccgcccg gccccggcgc cgcgcaaact
      601 ttgaatggga gcgccgcgcc gcccaccgcg ccgcacgccg cacctgctgt cagcccggtc
      661 aacaacgggc ccgcgccgcc gcccgccgcc ggctctgtca tccaggcggc ccccgcgccc
      721 gccgcgccct cgccgcccgc cgcgcccgcg cccgccgcgc ccccgcctcc cgcgcctcca
      781 gcgcccgtcg cgccagcccg gccgcccggg caccccgccg cgcccgcgcc ccccgtgtca
      841 cccgctgccg ccgccgccgc cgccgccgcc gccgcgcaga acggggccgc tcctgccccc
      901 gccgcggcct ccgggggcgc cgcggggttg ggccagccgg gcgcgggcgc gcagggggct
      961 aaggccgagg cgcccaagcc cggaccgggg cccgggccgg ggccggcggc ggcggcggcg
     1021 gcggcggcgg ggggggtcgc gggcgggggc gcggcgggcg gtgtgctgct cgggcccgcc
     1081 atgccgggcg cgctgccggg gcctgctccc gggacccccg cggggctggc gaagggcgcg
     1141 gccgcagcga cccccagcct gcctcggacg ccggcggcca ccaccggcgc tatccgggcc
     1201 acgctgacgc ccaccgtgtt ggccccgcgc ctgccgcagc cgccgcagaa cccgaccaac
     1261 atccagaact tccagctgcc cccaggaatg gtcctcgtgc ggagtgagaa tgggcagttg
     1321 ttaatgatcc ctcagcaggc cctggcccag atgcaggccc atgcccaggc ccagcctcag
     1381 agtaccatgg caccccgtcc tgcaaccccc acaggtgctg cacctgtcca gatctccacc
     1441 gtgcaggctc caggaacacc tattattgca cggcaggtga ccccaactac cataattaag
     1501 caagtgtctc aggcccagac gacggtacag cccactacaa ccctacagcg ctctcccggg
     1561 gtacagcctc agctggttct gggtggctcc gcacagccag cctcacttgg aacagccaca
     1621 gctgttcaga cagggacacc tcaacgtaca gtcaccgggg ccagcaccac ctccacagct
     1681 gccacggaaa ctatggaaaa tgtgaaaaag tgcaaaagtt ttctatctac attaataaag
     1741 ctggcttcct ctgggaaaca gtctacagag acagcggcta atgtgaaaga cctagtacaa
     1801 aacttactgg atgggaaaat cgaagcagaa gatttcacta gcaggttata tcgagaactg
     1861 aactcttcac ctcagcctta ccttgtgcct ttcctgaaga ggagcttacc tgccttgaga
     1921 cagctgaccc cagactccgc ggccttcatc cagcagagcc agcagcagca gccgcctgcc
     1981 tcgcaggcca cgactgcact gacggctgtg gtgctgagca gctcagtgca gcgcacagct
     2041 gggaagacag ctgcctcggt gaccagcgcc ctccagcccc cggtcatcag cctcacgcag
     2101 cccacacagg ttggcgttgg caagcaggca ccgcccacac cactggtgat ccagcagccc
     2161 ccgaagcctg gagccttgat ccggcccccg caggtgacct tgacgcagac acccatggtc
     2221 gcattgcggc agcctcacaa ccggatcatg ctcaccacac cacagcagat ccaactgaac
     2281 cagctgcagc cagtccctgt ggtgaaaccc accgtgttac ctggaaccaa agccctttct
     2341 actgtatctg cacaagcagc cgctgcacag aaaaacaagc tcaaggagcc agggggaggc
     2401 tcctttcggg atgatgacga catcaatgat gttgcgtcaa tggctggagt gaacctgtct
     2461 gaagaaagtg caagaatatt ggccacaaac tctgagttgg tggggacatt gacccgatcc
     2521 tgtaaagatg acaccttcct cctccccgcg cctttgcaga ggaggatact agaaataggt
     2581 aaaaagcacg gcatcacgga actgcatcca gatgtagtga gttacgtgtc tcatgccaca
     2641 cagcaaaggc tgcagaatct tgtagaaaag atatctgaaa cggctcagca gaaaaacttc
     2701 tcttataagg atgacgacag atatgagcaa gcgagtgatg tccgggcgca gctcaagttc
     2761 tttgaacagt tggatcagat tgaaaagcag aggaaagatg agcaggagag ggagatcttg
     2821 atgcgggcag caaagtctcg atccagacaa gaagacccag agcaattaag gttgaagcag
     2881 aaagcaaagg agatgcagca gcaggagctg gcacagatgc gacagcgaga tgccaacctc
     2941 actgcactgg cagccatcgg gcccaggaag aagaggaagg tggactgcgc tgggccagga
     3001 tcgggagcag agggctcagg cccaggcgca gcagtcccag gcggctccgg cgtgggaacc
     3061 cccagacagt tcacacggca aagaatcacg cgggtcaacc tcagggacct catattttgt
     3121 ttagaaaatg agcgtgagac aagccattca ctgttgctct acaaagcatt ccttaagtaa
     3181 caggatgagc cggcgtttct gatgggacgc ttgcggacgt ttttatatat ttgcagatta
     3241 cgcctttttg taacaagcaa atgggatatt gtttaaaaac agccacctct ttacaatgga
     3301 gcagttttat actcctgttt ataaatcagc tcttcagtgc ggcagaaacc gtgtctgcag
     3361 cagagagaac acaaaggcct gtggatgctc tcacaggaca gctgacccga gctcatcctc
     3421 ggctgagtgg ccttcttgcc aaacaagcca tatttaaaga ctgatggaag cgcttagcaa
     3481 ataattagca gttgctcatc ctgtgtgcgt tttggttccg ctcaccctga ctcacccgct
     3541 aggtgtccgt ctacagccga tgacctcatc tcttatttta cgttgtagca gtcagttggc
     3601 gaagcaaact gattttttag actatttatc acccctcccc gccctgtccc ttacctccct
     3661 tctatatgaa actccccagg atcataacct ccaagcaggg tcccatttct gctaatggag
     3721 gccggggtgc agcacctgta caaatatgtt ttatttgctg cagtttggaa gctgtaaagt
     3781 ggaaggaaat gagaaccttt tcagcataaa tatattttac ttgcactgtg tttttagctc
     3841 agagtgaaga cttagatgaa ataaaatcag agttgagaag aatcaacagc agactgtttc
     3901 tcagtgtgga tcaagtgttg gaaatggttg gtgtattttg tcagtaattg tacataattt
     3961 ttggcacata acataagatg gctatgtaaa ctataattat tttgctaaga gactgtatgc
     4021 aagctgtggc caaccttaca ggcgtccaga gcaaagcccc ttctttgtac ctattttttt
     4081 attacaaata tactaattgg ttctttatat tttcagaggt tattgtatta aattgtctat
     4141 gatagtactt ttatgactgt aaatacttgg ctttctccgt gtggattctc atgttagact
     4201 tcaattcgca cgtgtgaact gaacgctgat cagtattttt tatgacaccc aagaactgtt
     4261 acacctttca ttttatcttt taggaaatcc ccgtctttcc attttttcat gtaaattttg
     4321 cacagttact tgttaatatg taaatatttt actttcagaa atgaagtttt taattgctat
     4381 tgttttatat aggattgaaa gaaaattaac tcctttatta aaaacaaatt tatctgta
//
