LOCUS       NM_133319               5042 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus TATA-box binding protein associated factor 2
            (Taf2), mRNA.
ACCESSION   NM_133319 XM_001066741 XM_343241
VERSION     NM_133319.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5042)
  AUTHORS   Louder,R.K., He,Y., Lopez-Blanco,J.R., Fang,J., Chacon,P. and
            Nogales,E.
  TITLE     Structure of promoter-bound TFIID and model of human pre-initiation
            complex assembly
  JOURNAL   Nature 531 (7596), 604-609 (2016)
   PUBMED   27007846
  REMARK    Erratum:[Nature. 2016 Aug 4;536(7614):112. PMID: 27096372]
REFERENCE   2  (bases 1 to 5042)
  AUTHORS   Malkowska,M., Kokoszynska,K., Rychlewski,L. and Wyrwicz,L.
  TITLE     Structural bioinformatics of the general transcription factor TFIID
  JOURNAL   Biochimie 95 (4), 680-691 (2013)
   PUBMED   23146842
  REMARK    Review article
REFERENCE   3  (bases 1 to 5042)
  AUTHORS   Guermah,M., Ge,K., Chiang,C.M. and Roeder,R.G.
  TITLE     The TBN protein, which is essential for early embryonic mouse
            development, is an inducible TAFII implicated in adipogenesis
  JOURNAL   Mol Cell 12 (4), 991-1001 (2003)
   PUBMED   14580349
REFERENCE   4  (bases 1 to 5042)
  AUTHORS   Tomita,M., Nohno,T., Okuyama,T., Nishimatsu,S. and Adachi,J.
  TITLE     Paraquat-induced gene expression in rat lung tissues using a
            differential display reverse transcription-polymerase chain
            reaction
  JOURNAL   Arch Toxicol 76 (9), 530-537 (2002)
   PUBMED   12242611
REFERENCE   5  (bases 1 to 5042)
  AUTHORS   Martin,J., Halenbeck,R. and Kaufmann,J.
  TITLE     Human transcription factor hTAF(II)150 (CIF150) is involved in
            transcriptional regulation of cell cycle progression
  JOURNAL   Mol Cell Biol 19 (8), 5548-5556 (1999)
   PUBMED   10409744
REFERENCE   6  (bases 1 to 5042)
  AUTHORS   Brand,M., Yamamoto,K., Staub,A. and Tora,L.
  TITLE     Identification of TATA-binding protein-free TAFII-containing
            complex subunits suggests a role in nucleosome acetylation and
            signal transduction
  JOURNAL   J Biol Chem 274 (26), 18285-18289 (1999)
   PUBMED   10373431
REFERENCE   7  (bases 1 to 5042)
  AUTHORS   Martinez,E., Ge,H., Tao,Y., Yuan,C.X., Palhan,V. and Roeder,R.G.
  TITLE     Novel cofactors and TFIIA mediate functional core promoter
            selectivity by the human TAFII150-containing TFIID complex
  JOURNAL   Mol Cell Biol 18 (11), 6571-6583 (1998)
   PUBMED   9774672
REFERENCE   8  (bases 1 to 5042)
  AUTHORS   Kaufmann,J., Ahrens,K., Koop,R., Smale,S.T. and Muller,R.
  TITLE     CIF150, a human cofactor for transcription factor IID-dependent
            initiator function
  JOURNAL   Mol Cell Biol 18 (1), 233-239 (1998)
   PUBMED   9418870
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On or before Oct 25, 2008 this sequence version replaced
            XM_343241.3, XM_001066741.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760383, SAMEA5760386
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-296               JAXUCZ010000007.1  88369082-88369377   c
            297-351             JAXUCZ010000007.1  88368635-88368689   c
            352-512             JAXUCZ010000007.1  88363757-88363917   c
            513-631             JAXUCZ010000007.1  88362393-88362511   c
            632-773             JAXUCZ010000007.1  88360829-88360970   c
            774-1005            JAXUCZ010000007.1  88359966-88360197   c
            1006-1190           JAXUCZ010000007.1  88358008-88358192   c
            1191-1304           JAXUCZ010000007.1  88356986-88357099   c
            1305-1404           JAXUCZ010000007.1  88354804-88354903   c
            1405-1490           JAXUCZ010000007.1  88353259-88353344   c
            1491-1626           JAXUCZ010000007.1  88350867-88351002   c
            1627-1781           JAXUCZ010000007.1  88348200-88348354   c
            1782-1896           JAXUCZ010000007.1  88347437-88347551   c
            1897-2006           JAXUCZ010000007.1  88347021-88347130   c
            2007-2072           JAXUCZ010000007.1  88346272-88346337   c
            2073-2325           JAXUCZ010000007.1  88344564-88344816   c
            2326-2466           JAXUCZ010000007.1  88340357-88340497   c
            2467-2577           JAXUCZ010000007.1  88337442-88337552   c
            2578-2771           JAXUCZ010000007.1  88335112-88335305   c
            2772-2911           JAXUCZ010000007.1  88333597-88333736   c
            2912-2981           JAXUCZ010000007.1  88330853-88330922   c
            2982-3091           JAXUCZ010000007.1  88328176-88328285   c
            3092-3321           JAXUCZ010000007.1  88325490-88325719   c
            3322-3427           JAXUCZ010000007.1  88324327-88324432   c
            3428-3550           JAXUCZ010000007.1  88318977-88319099   c
            3551-5042           JAXUCZ010000007.1  88312374-88313865   c
FEATURES             Location/Qualifiers
     source          1..5042
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q32"
     gene            1..5042
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /note="TATA-box binding protein associated factor 2"
                     /db_xref="GeneID:170844"
                     /db_xref="RGD:621487"
     exon            1..296
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
     CDS             214..3816
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /note="TAF2 RNA polymerase II, TATA box binding
                     protein-associated factor, 150 kD; TAF2 RNA polymerase II,
                     TATA box binding protein (TBP)-associated factor"
                     /codon_start=1
                     /product="transcription initiation factor TFIID subunit 2"
                     /protein_id="NP_579853.1"
                     /db_xref="GeneID:170844"
                     /db_xref="RGD:621487"
                     /translation="MPPTGLESSRMNRKKGDKGFESPRPYKLTHQVVCINNINFQRKS
                     VVGFVELTIFPTVANLNRIKLNSKQCRIYRVRINDLEAAFIYNDPTLEVCHSESKQRN
                     LNYFSNAYAAAVSAVDPDAGNGELCIKVPSELWKHVDELKVLKIHINFSLDQPKGGLH
                     FVVPSVEGSMAERGAHVFSCGYQNSTRFWFPCVDSYSELCTWKLEFTVDAAMVAVSNG
                     DLVETVYTHDMRKKTFHYVLAIPTAASNISLAIGPFEILVDPYMHEVTHFCLPQLLPL
                     LKHTTSYLHEVFEFYEEILTCRYPYSCFKTVFIDEAYVEVAAYASMSIFSTNLLHSAM
                     IIDETPLTRRCLAQSLAQQFFGCFISRMSWSDEWVLKGISGYIYGLWMKKTFGVNEYH
                     HWIKEELDKIVAYELKTGGVLLHPIFGGGKEKDNPASHLHFSIKHPHTLSWEYYTMFQ
                     CKAHLVMRLIENRISMEFMLQVFNKLLSLASTASSQKFQSHMWSQMLVSTYGFLKSIS
                     NVSGKDIQPLIKQWVDQSGVVKFYGSFAFNRKRNVLELEIKQDYTSPGTQKYVGPLKV
                     TVQELDGSFNHTLQIEENSLKHDIPCHSKSRRNKKKKIPLMNGEEVDMDLSAMDADSP
                     LLWIRIDPDMSVLRKVEFEQADFMWQYELRYERDVVAQQESILALEKFPTPASRLALT
                     DILEQEQCFYRVRMSACFCLAKIANSMVSTWTGPPAMKSLFTRMFCCKTCPNIVKTNN
                     FMSFQSYFLQKTMPVAMALLRDVHNLCPKEVLTFILDLIKYNDNRKNKFSDNYYRAEM
                     IDALANSVTPAVSVNNEVRTLDNLNPDVRLILEEITRFLNMEKLLPSYRHTITVSCLR
                     AIRVLQKNGHVPSDASLFKSYAEYGHFVDIRIAALEAVVDYTKVDRSYEELQWLLNMI
                     QTDPVPYVRHKILNMLTKNPPFTKNMESPLCNEALVDQLWKLMNSGTAHDWRLRCGAV
                     DLYFTLFGLSRPSCLPLPELGLVLNLKEKKAVLNPTIIPEAGVGNQETASNPGCHTQL
                     AGFQNPFSSSQDEEEVDMDTVHDSQAFISHHLNMLERPSTPGLSKYRPSSSRSSLMPQ
                     HALGCDITPTTKPQWSMELSRKGAGKEQPLEMGVHPVAAPLSVFAKEALSSARHSEHH
                     HHHHHEHKKKKKKHKHKHKHKHKHDGKDKDKDKEPFTFSSPASGRSVRSPSLSD"
     exon            297..351
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
     exon            352..512
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
     exon            513..631
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
     exon            632..773
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
     exon            774..1005
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
     exon            1006..1190
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
     exon            1191..1304
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
     exon            1305..1404
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
     exon            1405..1490
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
     exon            1491..1626
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
     exon            1627..1781
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
     exon            1782..1896
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
     exon            1897..2006
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
     exon            2007..2072
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
     exon            2073..2325
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
     exon            2326..2466
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
     exon            2467..2577
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
     exon            2578..2771
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
     exon            2772..2911
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
     exon            2912..2981
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
     exon            2982..3091
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
     exon            3092..3321
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
     exon            3322..3427
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
     exon            3428..3550
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
     exon            3551..5042
                     /gene="Taf2"
                     /gene_synonym="TAFIIB"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcaagatgtc ggcaggcggc gtctgtggct ttgagctcct gtaaagcggc tcatctgtgt
       61 gacagggtta gggcgtagga gactgagagt ggccagggga ggggacacga ggcggaggaa
      121 gggtggctgg gccctcagag tgcacaggcc gctaccggga atgcgctgca gcctccggag
      181 cagcctgaaa ggcgagcccc gcaggagctc ttcatgccgc ccaccggctt agagtcctcc
      241 aggatgaaca ggaagaaagg agacaagggc ttcgaaagcc cacggccgta caaattaacc
      301 catcaggtcg tctgcatcaa caacataaac ttccagagaa agtctgttgt ggggtttgtg
      361 gagctgacta tatttcctac ggttgcaaac ttgaatagaa tcaagctgaa cagtaaacag
      421 tgtagaatat accgagtcag gatcaatgac ttggaggctg cttttattta taatgatcca
      481 accttagaag tttgtcacag cgaatcaaaa cagagaaacc tcaattattt ttccaatgcg
      541 tatgcagctg cagtcagtgc tgtggaccct gatgcgggga acggagaact ctgcattaag
      601 gtcccctcag agctctggaa gcacgtcgat gagttaaagg tcctgaagat acatattaat
      661 ttttctttgg atcagccaaa aggaggtctt cattttgtgg tacccagtgt agaggggagt
      721 atggcagaga gaggtgctca tgtcttctct tgtgggtatc agaattctac aagattttgg
      781 ttcccttgtg ttgattcata ctctgagttg tgtacctgga aattagaatt tacagtcgat
      841 gctgcgatgg tggctgtgtc caatggagat ttggtggaga cagtgtatac tcacgacatg
      901 agaaagaaga ccttccatta tgtgcttgct attcctacag cagcgtccaa tatctccttg
      961 gccatcgggc catttgaaat acttgtagat ccatatatgc acgaggttac ccatttttgt
     1021 ttgcctcaac ttcttccatt acttaaacat actacatcat accttcacga agtttttgaa
     1081 ttttatgagg aaattttgac ttgtcgctat ccgtactcct gttttaagac ggtcttcatt
     1141 gatgaggctt acgtggaagt ggccgcttat gcgtctatga gcattttcag cacaaatctc
     1201 ctgcacagcg ccatgattat agatgagaca ccgctcacca ggcggtgcct cgcacagtct
     1261 ctagcacagc agttcttcgg atgtttcatc tccagaatgt cttggtctga tgagtgggtg
     1321 ctgaagggaa tttcaggtta tatttatgga ctgtggatga agaaaacgtt tggtgtcaat
     1381 gagtaccacc attggattaa agaggaactc gataaaatag tggcatatga actgaaaact
     1441 gggggagttt tactgcatcc catatttggt ggtggaaaag aaaaggataa ccccgcatct
     1501 cacctccact tttcaataaa gcatccacat acactgtctt gggaatacta cactatgttt
     1561 cagtgtaaag ctcacctcgt gatgagactg attgaaaaca gaatcagcat ggaatttatg
     1621 ctgcaagttt tcaataaact attaagtctg gccagtaccg cttcatccca gaagttccag
     1681 tcacatatgt ggagccagat gctggtctcc acctacgggt ttttgaagtc catttccaat
     1741 gtctctggca aagacatcca gcccttaata aagcagtggg tagaccagag tggagtggta
     1801 aagttttatg gaagttttgc atttaataga aaacgaaatg ttttagaact agaaataaaa
     1861 caagattaca catctcctgg cacccagaag tacgtgggac cacttaaagt gacagtgcaa
     1921 gagttagacg gctccttcaa ccataccttg caaattgaag aaaacagcct taaacatgac
     1981 ataccctgcc actccaaaag cagaaggaat aagaagaaga aaatcccact gatgaatggg
     2041 gaagaagtcg atatggatct ttctgcaatg gatgcggact cccctttgct gtggataagg
     2101 atagacccag atatgtctgt cctgaggaag gtggagtttg agcaggctga ctttatgtgg
     2161 cagtatgagc tccgctatga gagagatgtt gttgctcagc aggaatccat cttggccttg
     2221 gaaaagttcc ccacgcccgc atcgcgcctc gcgctcactg atatactaga gcaagagcag
     2281 tgtttctacc gagtgaggat gtcagcatgc ttctgccttg caaagattgc aaactcaatg
     2341 gtgagcacat ggacgggacc accagccatg aagtccctct ttactagaat gttttgttgt
     2401 aaaacttgtc ccaacatcgt gaaaacaaac aacttcatga gctttcagag ttattttcta
     2461 cagaagacta tgccagttgc aatggctttg ttaagagacg tacataatct ttgtcccaaa
     2521 gaagttttaa catttatttt agacttaatc aagtacaatg acaacagaaa aaataagttt
     2581 tcagataact attaccgtgc agaaatgatt gatgccttgg ctaactctgt cacacctgct
     2641 gtcagcgtga ataatgaagt cagaactttg gataacttaa atcctgatgt gcgactaata
     2701 cttgaagaaa ttacccggtt tttgaatatg gaaaaacttc tcccaagtta cagacatact
     2761 atcactgtca gttgtttgag agccataaga gtgcttcaga agaatggaca tgtgccaagt
     2821 gatgcatctc ttttcaaatc ctatgctgag tatggccact tcgtggacat caggatagcg
     2881 gctctggaag ccgtcgtcga ttacaccaaa gtggacagga gttatgaaga acttcaatgg
     2941 ctacttaata tgattcagac tgaccctgtc ccctatgtga ggcataagat tctaaacatg
     3001 ctgactaaaa atccgccatt tacaaagaac atggagtctc ctttatgcaa cgaggccttg
     3061 gtagatcagc tctggaagct gatgaattct ggtactgcac atgactggag gttacggtgt
     3121 ggagctgtgg acttgtactt cacgctcttt ggcctcagta gaccttcttg tttacccttg
     3181 ccagagctcg ggcttgttct taacctaaaa gagaagaaag ctgtcttgaa tccaaccata
     3241 attccagaag cgggagtagg caatcaggaa actgcaagta acccaggctg tcacactcag
     3301 ctagcaggat ttcagaaccc tttctcaagt tctcaggatg aggaggaggt cgatatggac
     3361 accgttcatg atagtcaggc cttcatttcc catcatctga acatgcttga aaggccgtcc
     3421 actccagggc tctctaagta ccgaccatcc agctccaggt cttccttaat gccccagcat
     3481 gcattaggct gtgacatcac accaaccaca aaaccccagt ggagtatgga actgtcccga
     3541 aagggagcag gtaaagagca gcctttggag atgggtgtgc atcccgtggc ggccccgctc
     3601 tccgtgtttg ctaaggaggc tctgtcctct gcccggcaca gcgagcacca ccaccaccat
     3661 caccatgagc acaagaagaa gaagaagaag cacaaacaca agcacaagca caagcacaag
     3721 catgacggca aggacaagga caaggacaag gagcccttca ccttctccag ccctgccagt
     3781 ggcaggtctg tgcgctcccc ttcactctca gactgaagcc tgctccacag tcctctgtgc
     3841 agagacacag cagggactat ggcgaggctg aagaggatgc ttgaagtccc catttgacgg
     3901 ctgtgtttgt ataactggga tttaaatagg aatgagtgtt ttggttttgg aggaactgtt
     3961 ccacccccag ttcttcctga aaacagagcg actgtttata aaagccttcg tatccactgc
     4021 aggcctcttt agatgttggt ctcctatgga ctgccaaagt caggtgtgct tgacagcctt
     4081 ggatggacag aaggacattg tcagcagaag caactgcccg atctgtggta gccagcgttt
     4141 ccatgaagtg ctaaacagca ccacttgcaa ttgctggaga gaggcttttc tgtagggccc
     4201 aatccctctc gactgctttt tgtgttagcc attgaaacta agcaccatca tttatgagcg
     4261 aagaatccta tagttctttt taccctaaaa tataaaaagt tttgaaagaa attatttttt
     4321 aaacaattta aagtaactat cttttgatag tacatttggt gattatgata ttgcaatgta
     4381 gcagatccaa cattattctc aaatcaagat gttaaattat gttttgtttt gtcttccatt
     4441 aaatgcaggt gaatgtgttc agatgtaaaa tatgttttgc tgaatgtgga cagtttatac
     4501 acataacaca tattctctct gaaatgactc tgtatataag gcaggtgtgg ttgtgcatgc
     4561 ctgtaattcc agcagttggg agatagaggt caggatcatt caaggcctgc ctgacacaca
     4621 tgaaaatctg tatcacaaaa gcaaaatgac aaagtcactc tacataacaa aacatgatac
     4681 tttgaaaaag tgtctttatt tattgtttcc tagcttggtc acagctgatt tggcccacac
     4741 tggagtagac cagcagcagt ttaaataaac acacgtgcca tgctttgggt tcatagttta
     4801 acagtttgtg tggttgtatg ttttggtttt gttttttggc ttttgatttt ctgaatttcc
     4861 caggttctgg tgttaaaaaa tattttcata ttattcagtt ttatcatttc ttttgttact
     4921 aaatgtttga ctcaattctt gatctcagaa taaatatttc aaaagggatt caacaatgct
     4981 ggacttttaa atgtactttt agttgtattt aacttgttta gtaaataact tttttaagtc
     5041 tg
//
