LOCUS       NM_001191107            1962 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus TATA-box binding protein associated factor, RNA
            polymerase I subunit B (Taf1b), mRNA.
ACCESSION   NM_001191107 XM_001074480
VERSION     NM_001191107.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1962)
  AUTHORS   Maletzki,C., Huehns,M., Bauer,I., Ripperger,T., Mork,M.M.,
            Vilar,E., Klocking,S., Zettl,H., Prall,F. and Linnebacher,M.
  TITLE     Frameshift mutational target gene analysis identifies similarities
            and differences in constitutional mismatch repair-deficiency and
            Lynch syndrome
  JOURNAL   Mol Carcinog 56 (7), 1753-1764 (2017)
   PUBMED   28218421
REFERENCE   2  (bases 1 to 1962)
  AUTHORS   Knutson,B.A. and Hahn,S.
  TITLE     TFIIB-related factors in RNA polymerase I transcription
  JOURNAL   Biochim Biophys Acta 1829 (3-4), 265-273 (2013)
   PUBMED   22960599
  REMARK    Review article
REFERENCE   3  (bases 1 to 1962)
  AUTHORS   Schneider,D.A.
  TITLE     RNA polymerase I activity is regulated at multiple steps in the
            transcription cycle: recent insights into factors that influence
            transcription elongation
  JOURNAL   Gene 493 (2), 176-184 (2012)
   PUBMED   21893173
  REMARK    Review article
REFERENCE   4  (bases 1 to 1962)
  AUTHORS   Naidu,S., Friedrich,J.K., Russell,J. and Zomerdijk,J.C.
  TITLE     TAF1B is a TFIIB-like component of the basal transcription
            machinery for RNA polymerase I
  JOURNAL   Science 333 (6049), 1640-1642 (2011)
   PUBMED   21921199
REFERENCE   5  (bases 1 to 1962)
  AUTHORS   Knutson,B.A. and Hahn,S.
  TITLE     Yeast Rrn7 and human TAF1B are TFIIB-related RNA polymerase I
            general transcription factors
  JOURNAL   Science 333 (6049), 1637-1640 (2011)
   PUBMED   21921198
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Jul 17, 2010 this sequence version replaced XM_001074480.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360176.484205.1,
                                           SRR26360190.19550.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-18                JAXUCZ010000006.1  46846052-46846069
            19-117              JAXUCZ010000006.1  46847660-46847758
            118-205             JAXUCZ010000006.1  46861020-46861107
            206-303             JAXUCZ010000006.1  46865353-46865450
            304-399             JAXUCZ010000006.1  46865733-46865828
            400-550             JAXUCZ010000006.1  46872843-46872993
            551-701             JAXUCZ010000006.1  46875336-46875486
            702-801             JAXUCZ010000006.1  46883208-46883307
            802-949             JAXUCZ010000006.1  46909037-46909184
            950-1127            JAXUCZ010000006.1  46911649-46911826
            1128-1174           JAXUCZ010000006.1  46912516-46912562
            1175-1265           JAXUCZ010000006.1  46914426-46914516
            1266-1336           JAXUCZ010000006.1  46920635-46920705
            1337-1559           JAXUCZ010000006.1  46921218-46921440
            1560-1962           JAXUCZ010000006.1  46922807-46923209
FEATURES             Location/Qualifiers
     source          1..1962
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q16"
     gene            1..1962
                     /gene="Taf1b"
                     /gene_synonym="TAFI63"
                     /note="TATA-box binding protein associated factor, RNA
                     polymerase I subunit B"
                     /db_xref="GeneID:690450"
                     /db_xref="RGD:1596058"
     CDS             1..1761
                     /gene="Taf1b"
                     /gene_synonym="TAFI63"
                     /note="TBP-associated factor 1B; TATA box-binding
                     protein-associated factor 1B; TATA box binding protein
                     (Tbp)-associated factor, RNA polymerase I, B;
                     transcription initiation factor SL1/TIF-IB subunit B; RNA
                     polymerase I-specific TBP-associated factor 63 kDa"
                     /codon_start=1
                     /product="TATA box-binding protein-associated factor RNA
                     polymerase I subunit B"
                     /protein_id="NP_001178036.1"
                     /db_xref="GeneID:690450"
                     /db_xref="RGD:1596058"
                     /translation="MDVEQMKAFTDRCSQCAAVSWGLTDEGKYYCTSCHNVTDRSEEV
                     VSTAVIPNTKINSISRGLRQRSKHEKGWDWYVCEGFQCILYHQAEALETLGVSPELKN
                     EVLHSFWKRYLQKSKQAYCKNPVRTSGRKAKVLEDNLQSSDWGSDFELLSDTTCPPES
                     GAEFQSDSQTPKPFPATKRSSKSASVCSGSVDGVEYSERKEKGLLKMTVPRTLALCYL
                     SLLWQRETITLSDLLRFVEEDRIPYINAFKVFPEEMKVYGRDKGIFAVESWPDYEDIY
                     KNMIEVAVFLDLPRFPDITEDCYLHPNTLCMKYLLEVNLPEEMYTLTCQVVKLTGIGE
                     VDFLTFDPIAKMTRTVKHDVQAVAVIVLVLKLLFLLDDKLEWSYSDLAEAYNEGHKEE
                     TPQFDFRKWYQVMKKTFDEKRRKWEEARAKYVWKTKRPLYRSHIDKSVAYKRREMVEN
                     LQKQFSALIGSAPEVERQAPSSFQLNWTGEDTGSPCFHGHSLQGLLISKGQALITKNS
                     LYWLSTHKFCKSYCKHVTTYEESNFSLSYQFILNIFSFLLRIKTSALHEEVSLLEKKL
                     FEKKYNESKRSSRSKKVRRH"
     exon            1..18
                     /gene="Taf1b"
                     /gene_synonym="TAFI63"
                     /inference="alignment:Splign:2.1.0"
     exon            19..117
                     /gene="Taf1b"
                     /gene_synonym="TAFI63"
                     /inference="alignment:Splign:2.1.0"
     exon            118..205
                     /gene="Taf1b"
                     /gene_synonym="TAFI63"
                     /inference="alignment:Splign:2.1.0"
     exon            206..303
                     /gene="Taf1b"
                     /gene_synonym="TAFI63"
                     /inference="alignment:Splign:2.1.0"
     exon            304..399
                     /gene="Taf1b"
                     /gene_synonym="TAFI63"
                     /inference="alignment:Splign:2.1.0"
     exon            400..550
                     /gene="Taf1b"
                     /gene_synonym="TAFI63"
                     /inference="alignment:Splign:2.1.0"
     exon            551..701
                     /gene="Taf1b"
                     /gene_synonym="TAFI63"
                     /inference="alignment:Splign:2.1.0"
     exon            702..801
                     /gene="Taf1b"
                     /gene_synonym="TAFI63"
                     /inference="alignment:Splign:2.1.0"
     exon            802..949
                     /gene="Taf1b"
                     /gene_synonym="TAFI63"
                     /inference="alignment:Splign:2.1.0"
     exon            950..1127
                     /gene="Taf1b"
                     /gene_synonym="TAFI63"
                     /inference="alignment:Splign:2.1.0"
     exon            1128..1174
                     /gene="Taf1b"
                     /gene_synonym="TAFI63"
                     /inference="alignment:Splign:2.1.0"
     exon            1175..1265
                     /gene="Taf1b"
                     /gene_synonym="TAFI63"
                     /inference="alignment:Splign:2.1.0"
     exon            1266..1336
                     /gene="Taf1b"
                     /gene_synonym="TAFI63"
                     /inference="alignment:Splign:2.1.0"
     exon            1337..1559
                     /gene="Taf1b"
                     /gene_synonym="TAFI63"
                     /inference="alignment:Splign:2.1.0"
     exon            1560..1962
                     /gene="Taf1b"
                     /gene_synonym="TAFI63"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggacgtgg agcagatgaa agcattcaca gaccgctgtt ctcagtgcgc cgctgtctcc
       61 tggggcctta ctgatgaagg caaatactat tgtacctcct gccacaatgt cacagatcga
      121 tccgaggaag tcgtgagcac tgcagttatc cctaacacca agatcaactc cattagcagg
      181 ggcctgagac agagaagcaa gcatgagaaa ggctgggatt ggtacgtgtg tgaaggcttc
      241 cagtgcatac tttatcacca agcagaagcc ctggagaccc tcggagtaag cccagaacta
      301 aagaatgaag tcttgcacag tttttggaag cgctaccttc agaagagcaa gcaggcctat
      361 tgtaaaaacc cagttcgcac aagtggaagg aaagccaagg tattagaaga caatctgcag
      421 tcctctgact ggggcagtga ttttgagttg ctcagtgaca ccacatgtcc tcctgaaagt
      481 ggagcagagt tccagtctga ctcccagact ccaaagcctt tccctgccac caaacgatca
      541 tcaaagtcag catccgtctg ttctggatct gttgatggag tggagtactc agagcggaag
      601 gagaaggggc tcctgaagat gactgtgccc aggacacttg ccctctgcta tctgtccttg
      661 ctctggcaga gagaaacaat tacactttca gaccttttga ggtttgttga agaggaccgt
      721 attccataca taaatgcttt taaggttttt ccagaggaga tgaaagtata tggtcgtgac
      781 aaaggcatct ttgctgtcga gtcttggcct gactatgaag acatctataa aaacatgatt
      841 gaagtcgccg tgtttttaga tttgcctcgt ttcccagaca taactgaaga ctgctacctc
      901 catcccaaca ccttgtgtat gaaatactta ctggaggtca atctccctga ggaaatgtac
      961 actttaacct gccaagtagt aaagctgact ggaattggag aagtagattt tctgacgttt
     1021 gaccctatag ctaaaatgac aaggacagtc aaacatgatg tgcaggctgt ggctgtcatc
     1081 gtgcttgtgt tgaagctgct gtttctgctg gatgacaagc tggaatggtc ttactcagat
     1141 cttgctgaag catataacga aggacacaaa gaagaaactc cgcagtttga tttcagaaaa
     1201 tggtaccaag ttatgaagaa aacttttgat gagaaaagac gaaaatggga agaagcaagg
     1261 gccaagtatg tttggaaaac caaaaggcca ctctaccgtt cacacattga taagtcagtc
     1321 gcatataaga gaagagaaat ggtggagaat cttcagaaac agtttagtgc cctgattggt
     1381 tcagcacccg aggtggaaag gcaggcccct tcaagttttc agctcaactg gactggagaa
     1441 gacaccggta gcccttgttt ccatggacac agcctccagg ggctcctgat atcgaaaggc
     1501 caggccttga taaccaagaa ctccctgtac tggctcagta cccacaagtt ctgtaaaagc
     1561 tattgtaaac atgtgacaac ttacgaagaa tcaaattttt ctttgagtta ccagtttata
     1621 ctaaacattt tctccttctt actgagaata aagacctctg ctctccatga agaagtgagc
     1681 ctacttgaaa agaaactttt tgaaaaaaag tacaatgaat caaaaaggag ctcaagatcc
     1741 aagaaagtga gaagacattg agaagccaga ggggcttgct ctgaatggtg cgctattgga
     1801 taatgatgtc ttagcactat gttccaggga actatgtaaa gtctattgtt ggacaggcat
     1861 acattttgac aggtgtcttt atatgcattg taaaataggt gaactttgaa ttattttcat
     1921 gaacactttt tttcagaaaa ttaaaatatt atataaatga ta
//
