LOCUS       NP_001108508             161 aa            linear   ROD 24-JUN-2024
DEFINITION  transcription initiation factor TFIID subunit 12 [Rattus
            norvegicus].
ACCESSION   NP_001108508 XP_001065010
VERSION     NP_001108508.1
DBSOURCE    REFSEQ: accession NM_001115036.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 161)
  AUTHORS   Malkowska,M., Kokoszynska,K., Rychlewski,L. and Wyrwicz,L.
  TITLE     Structural bioinformatics of the general transcription factor TFIID
  JOURNAL   Biochimie 95 (4), 680-691 (2013)
   PUBMED   23146842
  REMARK    Review article
REFERENCE   2  (residues 1 to 161)
  AUTHORS   Knutson,B.A. and Hahn,S.
  TITLE     TFIIB-related factors in RNA polymerase I transcription
  JOURNAL   Biochim Biophys Acta 1829 (3-4), 265-273 (2013)
   PUBMED   22960599
  REMARK    Review article
REFERENCE   3  (residues 1 to 161)
  AUTHORS   Spedale,G., Timmers,H.T. and Pijnappel,W.W.
  TITLE     ATAC-king the complexity of SAGA during evolution
  JOURNAL   Genes Dev 26 (6), 527-541 (2012)
   PUBMED   22426530
  REMARK    Review article
REFERENCE   4  (residues 1 to 161)
  AUTHORS   Kamileri,I., Karakasilioti,I., Sideri,A., Kosteas,T., Tatarakis,A.,
            Talianidis,I. and Garinis,G.A.
  TITLE     Defective transcription initiation causes postnatal growth failure
            in a mouse model of nucleotide excision repair (NER) progeria
  JOURNAL   Proc Natl Acad Sci U S A 109 (8), 2995-3000 (2012)
   PUBMED   22323595
REFERENCE   5  (residues 1 to 161)
  AUTHORS   Schneider,D.A.
  TITLE     RNA polymerase I activity is regulated at multiple steps in the
            transcription cycle: recent insights into factors that influence
            transcription elongation
  JOURNAL   Gene 493 (2), 176-184 (2012)
   PUBMED   21893173
  REMARK    Review article
REFERENCE   6  (residues 1 to 161)
  AUTHORS   Shao,H., Revach,M., Moshonov,S., Tzuman,Y., Gazit,K., Albeck,S.,
            Unger,T. and Dikstein,R.
  TITLE     Core promoter binding by histone-like TAF complexes
  JOURNAL   Mol Cell Biol 25 (1), 206-219 (2005)
   PUBMED   15601843
REFERENCE   7  (residues 1 to 161)
  AUTHORS   Guermah,M., Ge,K., Chiang,C.M. and Roeder,R.G.
  TITLE     The TBN protein, which is essential for early embryonic mouse
            development, is an inducible TAFII implicated in adipogenesis
  JOURNAL   Mol Cell 12 (4), 991-1001 (2003)
   PUBMED   14580349
REFERENCE   8  (residues 1 to 161)
  AUTHORS   Martinez,E., Palhan,V.B., Tjernberg,A., Lymar,E.S., Gamper,A.M.,
            Kundu,T.K., Chait,B.T. and Roeder,R.G.
  TITLE     Human STAGA complex is a chromatin-acetylating transcription
            coactivator that interacts with pre-mRNA splicing and DNA
            damage-binding factors in vivo
  JOURNAL   Mol Cell Biol 21 (20), 6782-6795 (2001)
   PUBMED   11564863
REFERENCE   9  (residues 1 to 161)
  AUTHORS   Ogryzko,V.V., Kotani,T., Zhang,X., Schiltz,R.L., Howard,T.,
            Yang,X.J., Howard,B.H., Qin,J. and Nakatani,Y.
  TITLE     Histone-like TAFs within the PCAF histone acetylase complex
  JOURNAL   Cell 94 (1), 35-44 (1998)
   PUBMED   9674425
REFERENCE   10 (residues 1 to 161)
  AUTHORS   Wieczorek,E., Brand,M., Jacq,X. and Tora,L.
  TITLE     Function of TAF(II)-containing complex without TBP in transcription
            by RNA polymerase II
  JOURNAL   Nature 393 (6681), 187-191 (1998)
   PUBMED   9603525
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473968.1.
            
            On Mar 2, 2008 this sequence version replaced XP_001065010.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC158610.1, FQ225384.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132263
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..161
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     Protein         1..161
                     /product="transcription initiation factor TFIID subunit
                     12"
                     /note="TAF12 RNA polymerase II, TATA box binding protein
                     (TBP)-associated factor"
                     /calculated_mol_wt=17802
     Region          55..128
                     /region_name="HFD_TAF12"
                     /note="histone-fold domain found in transcription
                     initiation factor TFIID subunit 12 (TAF12) and similar
                     proteins; cd07981"
                     /db_xref="CDD:467025"
     Site            order(55..58,62,66,69..70,84,87..89,91..93,96..97,100,103,
                     111..113,116..117,120,124,126,128)
                     /site_type="other"
                     /note="heterodimer interface [polypeptide binding]"
                     /db_xref="CDD:467025"
     Site            order(76,80,84,105..107,118,122)
                     /site_type="other"
                     /note="oligomer interface [polypeptide binding]"
                     /db_xref="CDD:467025"
     CDS             1..161
                     /gene="Taf12"
                     /coded_by="NM_001115036.1:161..646"
                     /db_xref="GeneID:682902"
                     /db_xref="RGD:1592841"
ORIGIN      
        1 mnqfgpsali nlssfssikp epastppqgs mansttvgkm pgtpgtggrl spennqvltk
       61 kklqdlvrev dpneqldedv eemllqiadd fiesvvtaac qlarhrksst levkdvqlhl
      121 erqwnmwipg fgseeirpyk kactteahkq rmalirkttk k
//
