LOCUS       NM_001004107            7632 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus transforming, acidic coiled-coil containing
            protein 1 (Tacc1), mRNA.
ACCESSION   NM_001004107 XM_224961
VERSION     NM_001004107.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 7632)
  AUTHORS   Guyot,R., Vincent,S., Bertin,J., Samarut,J. and Ravel-Chapuis,P.
  TITLE     The transforming acidic coiled coil (TACC1) protein modulates the
            transcriptional activity of the nuclear receptors TR and RAR
  JOURNAL   BMC Mol Biol 11, 3 (2010)
   PUBMED   20078863
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7632)
  AUTHORS   Xie,Z., Moy,L.Y., Sanada,K., Zhou,Y., Buchman,J.J. and Tsai,L.H.
  TITLE     Cep120 and TACCs control interkinetic nuclear migration and the
            neural progenitor pool
  JOURNAL   Neuron 56 (1), 79-93 (2007)
   PUBMED   17920017
REFERENCE   3  (bases 1 to 7632)
  AUTHORS   Lau,N.C., Seto,A.G., Kim,J., Kuramochi-Miyagawa,S., Nakano,T.,
            Bartel,D.P. and Kingston,R.E.
  TITLE     Characterization of the piRNA complex from rat testes
  JOURNAL   Science 313 (5785), 363-367 (2006)
   PUBMED   16778019
REFERENCE   4  (bases 1 to 7632)
  AUTHORS   Still,I.H., Vettaikkorumakankauv,A.K., DiMatteo,A. and Liang,P.
  TITLE     Structure-function evolution of the transforming acidic coiled coil
            genes revealed by analysis of phylogenetically diverse organisms
  JOURNAL   BMC Evol Biol 4, 16 (2004)
   PUBMED   15207008
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7632)
  AUTHORS   Delaval,B., Ferrand,A., Conte,N., Larroque,C., Hernandez-Verdun,D.,
            Prigent,C. and Birnbaum,D.
  TITLE     Aurora B -TACC1 protein complex in cytokinesis
  JOURNAL   Oncogene 23 (26), 4516-4522 (2004)
   PUBMED   15064709
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. This record has been curated by NCBI staff in
            collaboration with Ivan Still. The reference sequence was derived
            from JAXUCZ010000016.1.
            
            On Feb 10, 2021 this sequence version replaced NM_001004107.3.
            
            Summary: This gene encodes a member of the transforming, acidic
            coiled-coil (TACC) family of proteins. Members of this family are
            centrosomal proteins that interact with microtubules and tubulin.
            TACC proteins are thought to be involved in centrosome/mitotic
            spindle dynamics and gene regulation. [provided by RefSeq, Jul
            2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360172.1705308.1,
                                           SRR21887622.546382.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-407               JAXUCZ010000016.1  73547704-73548110
            408-523             JAXUCZ010000016.1  73549026-73549141
            524-1622            JAXUCZ010000016.1  73570939-73572037
            1623-1683           JAXUCZ010000016.1  73575815-73575875
            1684-1804           JAXUCZ010000016.1  73578402-73578522
            1805-1857           JAXUCZ010000016.1  73582214-73582266
            1858-1983           JAXUCZ010000016.1  73584521-73584646
            1984-2060           JAXUCZ010000016.1  73586229-73586305
            2061-2104           JAXUCZ010000016.1  73586711-73586754
            2105-2265           JAXUCZ010000016.1  73587943-73588103
            2266-2372           JAXUCZ010000016.1  73588928-73589034
            2373-2493           JAXUCZ010000016.1  73591879-73591999
            2494-7632           JAXUCZ010000016.1  73593254-73598392
FEATURES             Location/Qualifiers
     source          1..7632
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16q12.4"
     gene            1..7632
                     /gene="Tacc1"
                     /gene_synonym="Tacc1a"
                     /note="transforming, acidic coiled-coil containing protein
                     1"
                     /db_xref="GeneID:306562"
                     /db_xref="RGD:1303120"
     exon            1..407
                     /gene="Tacc1"
                     /gene_synonym="Tacc1a"
                     /inference="alignment:Splign:2.1.0"
     CDS             244..2562
                     /gene="Tacc1"
                     /gene_synonym="Tacc1a"
                     /note="transforming, acidic coiled-coil containing protein
                     1a"
                     /codon_start=1
                     /product="transforming acidic coiled-coil-containing
                     protein 1"
                     /protein_id="NP_001004107.1"
                     /db_xref="GeneID:306562"
                     /db_xref="RGD:1303120"
                     /translation="MAFSPWQILSPVQWAKWTWSAVRGSGAGEDEAGGPEGDPEEEED
                     SQAETKSLSFSSDSEGNFETPEAETPIRSSLKESCDSSLGLSEPEAKPQESREADEQP
                     VAELIEKCSPDACSRSSGNEAPQATIDSYSVKDVRGKAEHDVSKISVVRPFSIETRDC
                     TDDPAAHGCVPVLPGKALPSTTPEATQDQPMMDRGMGVTLEAFTEVNLKTGGPCPEPV
                     PSRSRLRKPKPVSLRKKTAGDNTFEPEMLMEGSLLPKASSPWIPEESDKNSNPSLLRG
                     LRAHKSPLNLKEAASIHCNSAGDSGVDLQEGSRASPLKLDDFTEDGRSVETRSALPKQ
                     PGRKPSHKLAPNIRKDGSSKPVGVEQLTDPTIEDASLAQTSPKLDPSKWGRPNFNSFG
                     SCPILQSSPPVSSKGSYHLDPDNVNADESGDPCKPATALTGSGFCSATGNHVNEILDS
                     PKKAQSRLITSGCKVKKYETQSLDLDACSQDEGAVISQIADIPNRDGHATDEEKLAST
                     SCSQKSAGAEVKGVEKEAYQKMEEEELTVHGLLETSSEKAPVSVACGGESPLDGICLS
                     EADKTAVLTLIREEIITKEIEANEWKKKYEETREEVLEMRKIVAEYEKTIAQMIEDEQ
                     RTNMSSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKC
                     AQDYLARVKQEEQRYQALKVHAEEKLDRANEEIAQVRSKAKAESAALHAGLRREQMKV
                     ESLERALQQKNQEIEELTKICDELIAKLGKAD"
     exon            408..523
                     /gene="Tacc1"
                     /gene_synonym="Tacc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            524..1622
                     /gene="Tacc1"
                     /gene_synonym="Tacc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            1623..1683
                     /gene="Tacc1"
                     /gene_synonym="Tacc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            1684..1804
                     /gene="Tacc1"
                     /gene_synonym="Tacc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            1805..1857
                     /gene="Tacc1"
                     /gene_synonym="Tacc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            1858..1983
                     /gene="Tacc1"
                     /gene_synonym="Tacc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            1984..2060
                     /gene="Tacc1"
                     /gene_synonym="Tacc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            2061..2104
                     /gene="Tacc1"
                     /gene_synonym="Tacc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            2105..2265
                     /gene="Tacc1"
                     /gene_synonym="Tacc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            2266..2372
                     /gene="Tacc1"
                     /gene_synonym="Tacc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            2373..2493
                     /gene="Tacc1"
                     /gene_synonym="Tacc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            2494..7632
                     /gene="Tacc1"
                     /gene_synonym="Tacc1a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagcaggact gggggacagg caggcgggcg ggcgcgcgcg ggggcgagct tcggcgcggc
       61 ggccccgagg agcgggggcg agcggcgctg cggggccgtg ggaggaagcg ctgcgcccgg
      121 cccgacggcg ctcgttgagc cacatccgcg ggtcgccggc gacgttgccg gcgcctgtca
      181 aggcccctcc attttgaagg aagaggccgc cgtttcccca ccgcaggggc ggtagccgcg
      241 ctcatggcgt tcagtccctg gcagatcctg tcgcccgtgc agtgggccaa gtggacgtgg
      301 tccgcggtgc gcggttcggg cgcgggagag gacgaagctg gaggtcccga aggcgacccc
      361 gaggaggaag aggactcgca agccgagacc aaatccctga gtttcagctc ggattctgaa
      421 ggtaattttg agactcctga agctgaaact ccaatcagat cgtctctcaa ggagtcttgt
      481 gattcatcac taggattgtc agaacccgag gccaaacccc aagaatcacg agaagccgat
      541 gaacagccgg tagcagaatt aattgaaaaa tgctcgcctg atgcgtgttc tagatcttca
      601 ggaaatgaag cgccacaggc cactatcgat tcttactcag tcaaggatgt cagagggaag
      661 gcggaacatg atgttagcaa gatctcagta gtgaggccgt tttccataga aaccagggac
      721 tgcacagatg accctgctgc tcatggctgt gtccctgtgc tcccaggcaa ggccttgcct
      781 tccaccacac ccgaagccac tcaggaccag ccaatgatgg acagaggcat gggggttaca
      841 ttggaggctt ttacagaagt caatctgaag actggaggcc cctgcccaga gcctgtgccc
      901 agcagaagca ggctaagaaa gcccaagcct gtctccctga ggaagaagac agctggggac
      961 aacacctttg aacccgaaat gttgatggag ggttcacttc tccctaaggc ttcctccccg
     1021 tggattcctg aggagtctga taagaactcg aatcctagtt tgctgagagg cttgagggcc
     1081 cacaaatctc cccttaacct taaagaagct gctagcattc actgtaacag cgccggtgac
     1141 tcgggggttg atctgcagga ggggtccagg gcctcacctc tcaaacttga tgattttaca
     1201 gaagacgggc ggagtgtcga gaccaggagt gcccttccga agcagcctgg caggaaaccc
     1261 agccacaaac tggcacccaa tatacgaaaa gatggctcca gtaagccagt aggtgttgag
     1321 cagctcacag acccaaccat tgaagatgcc tccctcgccc agacgtctcc caagttagac
     1381 ccaagtaaat ggggtcgtcc taactttaat tccttcggga gctgccccat tttgcagagc
     1441 tccccgcccg tctcctccaa aggttcctac caccttgacc cagataacgt taacgccgat
     1501 gaatccgggg acccctgtaa gccggcgaca gctttgacag gcagcggctt ttgctctgcc
     1561 actggtaatc atgttaatga aatcttagac tcacccaaga aggcacagtc gcgtttaata
     1621 acgagtggct gcaaggtgaa gaaatacgaa actcagtctc ttgatttgga cgcttgttct
     1681 caggatgaag gagccgtgat ctcacagatt gcagacattc ctaatcggga cgggcacgcc
     1741 accgatgagg agaagctggc gtccacgtcg tgtagtcaga agtcagccgg ggctgaagtg
     1801 aaaggcgtag aaaaggaggc ataccagaag atggaggagg aggagctgac tgtgcatgga
     1861 ctgctggaga cctcttcaga aaaggccccc gtgtctgtgg cctgtggagg tgagagccct
     1921 ctggatggga tctgcctcag tgaagcagac aagactgctg tgcttacatt gatcagagaa
     1981 gagatcatca cgaaagagat tgaagcaaat gaatggaaga agaaatacga agagacccga
     2041 gaagaagtcc tggagatgag gaaaattgtg gcagaatatg aaaagaccat tgcccaaatg
     2101 atcgaagacg agcagaggac aaacatgagc tctcagaaga gtttccagca gctgactatg
     2161 gagaaggagc aggctctggc tgacctgaac tctgtggaaa ggtccctttc tgatctcttc
     2221 agaagatatg aaaacctgaa aggcgtgcta gaagggttca agaagaatga agaagccttg
     2281 aaaaagtgtg ctcaggatta cttagccaga gtgaagcagg aagagcagcg ctaccaggcc
     2341 ctgaaggtcc acgctgagga aaagctggac agagccaacg aggaaatcgc tcaggttcgg
     2401 tccaaggcga aggctgagag tgcggctctc catgctggac tccggaggga gcagatgaag
     2461 gtggagtccc tggagagggc ccttcagcag aagaatcaag agattgaaga actgacaaaa
     2521 atctgtgacg agttgatcgc aaagcttgga aaggccgact gagagtcgtc ccgtgagctg
     2581 tgcagatccg agtctggctg cttctgtcgt gaccacatta tcttgcctta tccagaaata
     2641 tctcccccct ttgcagagaa aaataactgt ttcaaaagca catgcctgct gctgcccgcc
     2701 tgtccgtccc gcttcgccgc gcgcagctgt ggccaggctg gtggagatgg agtcacgtga
     2761 ccgcagagcc ccgcgaccag gctgccagct tcccttaggc acgctgctgc tgggtccggc
     2821 ttatgcttct ccaacttgag ttcatctcgc tgtcgtcctt gcttttccca agtttgtgac
     2881 atttctaatt ttgtggcaac tgtgtgggtt tatcttccca gctcctgata tttctatggc
     2941 ctagttaacc tttaaaattt tcaggatcgt cagttttatc gaagcggggg acggtctggc
     3001 ccatcattac gaacactttg tctaggaggc tccaagctcc cttttattta cagactgtac
     3061 attctgctgc tccccacccc accccctcga tgcagataag agcctctagg gaggagtttg
     3121 gctacataaa taaatataga ctcttatttt gaaacagagc cgtaggtcta aaagccagct
     3181 tcagacttca caggggctgg gaatgtagct ccgttagtag acagcttcct gtacacagag
     3241 ccctgggttt ggcccccaga atgttggagg gcgtgcctgt aacccaaccc tccagaggtg
     3301 gagacaggct gatgagaaat ttgaggtcat cctcaactac atagccactc ggaggccagc
     3361 ctggactaac tacatggggc cttgctttac acaaggagtg agtggaagca tggggtatcc
     3421 tagctagtgg gagatgggac aggacgatca cttgagccca gaatttaagg acagcagtgc
     3481 accaggcaaa tagtcctttt ctcaaaaatc ctactaaacc ttgagtcagg gtggagaggt
     3541 tgagcgtgtg aaggccaggg gacataggtt tcacgtctag ggaagatttg ctgtgccgtc
     3601 tcttgccccg gtatttggac acctcagaag ctcagcgtgg ccccacgcgc tcatgctgaa
     3661 agcagcatca cgtgaccagc agcataaacc tccctcagag ttggcctagg ctgcatgtgt
     3721 ccacttgggg ccggttagtc tccgaaacaa agtcaacttt tgtcatctat ttgaaacaca
     3781 cacaaatggg acttgggaaa ggtttagttg atcttgttaa aagatggtgg acgcttacaa
     3841 accagttaga gtgaagatcc ttaatcttct atgtttacta gcagacagca cccttttaga
     3901 gacttaaaaa caacagccac aacaaattct tccttcctta ctcaagctgg gttttaaaac
     3961 aaaacaggca gtaaagagtc cagtagctcc cctgggcata ttttaagcaa agactgcttg
     4021 aatgctgggg aggggaatag ggagaagttc cacatagaca aaacaaaagt ctgtgaactc
     4081 atactggact tacactgggg gacattaacc cccaaataag aataccccac attggcactg
     4141 gtgacttcct ttccatgata ggcaaagcca aacccattta ggttttattg cttttatttt
     4201 gccttaatct taacaccctg agtcttcata gtaagtgtac actatttagt acacatatat
     4261 tttcctcctt gtaacaccgt tgcatgagcc aagtccagca atgaattgtg cctcgtagag
     4321 agcctccata gatcttataa acagtgtcct tagcagcgcg ttaccatgtg gtgtaacctt
     4381 tagccccagg gaagcaatgt cttttcaagc tagaaatcac atcttgtcaa tatgcattta
     4441 ttataacagg tgcttaagtt aggctgtatc ctgaggccta ctgtctttta accttttgta
     4501 caaaaaaaca caagcagaca gaagttatct gtggttggag aaatggcttg acaatcattt
     4561 gggctctgaa tttagtcaca gtggcttaac gtgaagccca tagcagtaca tgtagtgtcg
     4621 tgttcaagtg tcttcaaggg atagacccag tgccagcttg gccatcttcc tcaagggaag
     4681 ctaattttgc attttaagaa cccccctccc caaccccgcg gaaatttctg ctacagtgtt
     4741 acagcggcat cagtgtgtgt gctcatttta tattgactta ttttcagtat gcaagccttc
     4801 agagtggtct ctattataaa cctcttattt cctatttttt ttttcttttt ggtagtactg
     4861 agattgtacc cagggtcttg aacatgccag gcaagtgctt ggccgtggga ctacatcttc
     4921 cccggtcatc tttttaagca tgcatgtttt taaagcatct tgtgctgtgc tgtgtgtaac
     4981 caaggcacag gagaggagtg gtgaccgtcc ctccttgcct cactggcaga caggccttga
     5041 aaaacaggcc ttgataaatg tccccatgtg cagagggcat aaactagccc tctaagcaat
     5101 gtttgccagt ggcctcttag tcacccccat caccaggaaa tgtcacagct tctagcttct
     5161 ggagattctc caacaggaat aagaatgtag cccgcgcagc tggcaaatta agaagatata
     5221 ctagtctatt tattttcttt taattaaata agccctaaaa agctttttag cactctggag
     5281 agtaaaaata taaagttttc ttcaccacat gctgggggcc aaatgctttt tttgttaagt
     5341 gattaaaagg gggttggggt gggggaccag gcctggtggc acatgcagat aatcctaagt
     5401 aaatcccagc accctggagg caggcaggga ccagaagttc aggctttgac tgggctatac
     5461 tgtgaggccc ttgtcttctc gagagctgga gctgtgactc agtggtagtg ttgccaatcc
     5521 ccggcactgt aaaaataaat aacaaaagat ttaaaataca agagaaatgc tccgagtggc
     5581 ttaggaatat taggtgatct tgttgacact ctcagcatag aactgttcct tcagttccgc
     5641 actgccaaag tccagacgac tcttgcctgt cagtcagtac cacagacgga cgggtttact
     5701 gtgtgctgga aggcggcgct tactctgttt ggagaccggg agtcccccca gacttggtat
     5761 tctctgaagc tctagtgcgg actcaagcgt cttcagaaac agaccaaact aacaagtgcg
     5821 gaacggagca cgcggttggg aggccgggag cgagcgcgta ggatgaaatc cctgacttca
     5881 gggttagagc ttaagctaaa ctttgtttcc aaccctgttc tccctgcaga cttggcactg
     5941 cctgcgcaca catgtctgca cactcgctcg gcagcctggg ttgagcctgg ccggccgaag
     6001 tcctcgcttt cagcaaagat cgcacaggct agaaagggca ctcggcggcc cacgggcttt
     6061 caggatctgt ggcctaagct caaggcatac tgaattgaag gtggtgtgga ccttctgaag
     6121 cccctcccga attccctgag gctcatttca gctggtgatc tcacgcctca gctgcccctg
     6181 ctgtctctgt gggactgtgg ccctctaagc tcgctctcag gttttttgtt tttttaaatc
     6241 ttcttgggaa gagagaatat agatgttgaa agagtacaaa atagatttag gcaaggagtt
     6301 tagagatgtc tatattatga agcattttaa gggtaacaga ttattattta cttaccaatg
     6361 aacaggtaag gtctggggat cccagaccgc caagccaaag gtggaagaaa tcgcctttca
     6421 aaaagtttta acaatgaagt tatttcaaag gagactaatg tccaagaaag gtttgactgg
     6481 cctccagatt ccgattattt tttaaaaagc aatttaccag ggctggggat gtagttcagt
     6541 tggtgacaca cttgctcagc acaagtccct gaatgtcatt ccccagtgct gggggaaaat
     6601 cagaaaaaaa gaaatattta ctactaagtc cttcctgata tggagagaaa agggagacgc
     6661 gtgtagaacc aggtcttctc cataggcgtt tctagaacag ttcaggcgag cacttggccc
     6721 ctcggagagc gaagctcgca cttctagtcc ttcccaccca gatgcagcgc cccctgtctg
     6781 tgcctctcag catgcagtta gatttggaca aataagattc ccgaggaatg actttctcca
     6841 tgacaccacg gtttcagctt tatgtaaaca cacacacatc cccttatagt tctagtctgg
     6901 agatgctgct gccatgctgg cctcaggtag actgtgtgat gtttttacca ctcagaggag
     6961 gccaagcgtg gggctgaggt gtggcctgaa ccttccctgt atggagtctt caataccaac
     7021 tctcaggatg ccacgctacc ccctgccttc tcgtggcatc tgagtacact cagcaaaagc
     7081 acttccccac atcacgaaag aaactgattc ggtatttgtg aatcactttg caaatggaca
     7141 cacagaaatc tgagctctga aactccatcc agaccagata cagggcagtg tgaagatcac
     7201 accctcagcc tcagtgctgt ccctcaaagt ccttgggaga ggactcagac actcggatga
     7261 gtctccaagg cacctgtcaa ctttctagta ttgccgttag cgagtctgtg tttgccaata
     7321 gatacccact gtactaacgt gccaagtgtt tatttgcaca tctgcttcca ctgtgtccag
     7381 cacccacccc ccaaccccac ctcctggtgc cccggagtgg caggggggca cacactgcat
     7441 tgactcctgc tgtcaggacg gtgttgtgca gaataatcat cctcatagat tttatacaca
     7501 tagtaattcc cctttttata tgtcaggtaa atatttgtaa aagttatact cacacaaaag
     7561 aaattattat gataattact aatatatttt ttccatgttt cattgcctga ataaaaactg
     7621 tttaccactg tt
//
