LOCUS       NP_783190                344 aa            linear   ROD 20-AUG-2024
DEFINITION  trace amine-associated receptor 8c [Rattus norvegicus].
ACCESSION   NP_783190
VERSION     NP_783190.2
DBSOURCE    REFSEQ: accession NM_175600.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 344)
  AUTHORS   Ferrero,D.M., Wacker,D., Roque,M.A., Baldwin,M.W., Stevens,R.C. and
            Liberles,S.D.
  TITLE     Agonists for 13 trace amine-associated receptors provide insight
            into the molecular basis of odor selectivity
  JOURNAL   ACS Chem Biol 7 (7), 1184-1189 (2012)
   PUBMED   22545963
REFERENCE   2  (residues 1 to 344)
  AUTHORS   Lindemann,L., Ebeling,M., Kratochwil,N.A., Bunzow,J.R., Grandy,D.K.
            and Hoener,M.C.
  TITLE     Trace amine-associated receptors form structurally and functionally
            distinct subfamilies of novel G protein-coupled receptors
  JOURNAL   Genomics 85 (3), 372-385 (2005)
   PUBMED   15718104
REFERENCE   3  (residues 1 to 344)
  AUTHORS   Borowsky,B., Adham,N., Jones,K.A., Raddatz,R., Artymyshyn,R.,
            Ogozalek,K.L., Durkin,M.M., Lakhlani,P.P., Bonini,J.A.,
            Pathirana,S., Boyle,N., Pu,X., Kouranova,E., Lichtblau,H.,
            Ochoa,F.Y., Branchek,T.A. and Gerald,C.
  TITLE     Trace amines: identification of a family of mammalian G
            protein-coupled receptors
  JOURNAL   Proc Natl Acad Sci U S A 98 (16), 8966-8971 (2001)
   PUBMED   11459929
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Jul 7, 2022 this sequence version replaced NP_783190.1.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on computational evidence
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1p12"
     Protein         1..344
                     /product="trace amine-associated receptor 8c"
                     /note="taR-10; taR-8c; trace amine receptor 8c; trace
                     amine receptor 10"
                     /calculated_mol_wt=37915
     Site            4
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q923Y0.1)"
     Site            18
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q923Y0.1)"
     Region          32..323
                     /region_name="7tm_GPCRs"
                     /note="seven-transmembrane G protein-coupled receptor
                     superfamily; cl28897"
                     /db_xref="CDD:475119"
     Region          34..58
                     /region_name="TM helix 1"
                     /note="TM helix 1 [structural motif]"
                     /db_xref="CDD:410628"
     Site            37..57
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q923Y0.1)"
     Region          67..89
                     /region_name="TM helix 2"
                     /note="TM helix 2 [structural motif]"
                     /db_xref="CDD:410628"
     Site            68..88
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q923Y0.1)"
     Site            103..127
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q923Y0.1)"
     Region          105..127
                     /region_name="TM helix 3"
                     /note="TM helix 3 [structural motif]"
                     /db_xref="CDD:410628"
     Site            147..167
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q923Y0.1)"
     Region          150..166
                     /region_name="TM helix 4"
                     /note="TM helix 4 [structural motif]"
                     /db_xref="CDD:410628"
     Region          194..217
                     /region_name="TM helix 5"
                     /note="TM helix 5 [structural motif]"
                     /db_xref="CDD:410628"
     Site            197..217
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q923Y0.1)"
     Region          258..280
                     /region_name="TM helix 6"
                     /note="TM helix 6 [structural motif]"
                     /db_xref="CDD:410628"
     Site            261..281
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q923Y0.1)"
     Region          291..316
                     /region_name="TM helix 7"
                     /note="TM helix 7 [structural motif]"
                     /db_xref="CDD:410628"
     Site            296..319
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q923Y0.1)"
     CDS             1..344
                     /gene="Taar8c"
                     /gene_synonym="Ta10"
                     /coded_by="NM_175600.2:1..1035"
                     /db_xref="GeneID:319105"
                     /db_xref="RGD:631390"
ORIGIN      
        1 mtsnfsqatl qlcyenvnas ciktpyspgl rvllymvfgf gtvlavcgnl lvvisvlhfk
       61 qlhspanfli aslasadflv gisvmpfsmv rsiescwyfg dtfcslhscc dvafcyssal
      121 hlcfisvdry iavtdplvyp tkftvsvsgi cisiswilpl vyssavfytg isamgienlv
      181 salncvggcq vvvnqdwvli sfllffiptl vmiilyskif lvakqqavki etsvsgskge
      241 ssleshkarv akrerkaakt lgvtvlafiv swlpytidtl idafmgfitp ayvyefccws
      301 ayynsamnpl iyaffypwfr kamklilsgk ilkghsstts lfse
//
