LOCUS       NM_001398614            7286 bp    mRNA    linear   ROD 12-AUG-2024
DEFINITION  Rattus norvegicus synaptotagmin 7 (Syt7), transcript variant 1,
            mRNA.
ACCESSION   NM_001398614 XM_006231065
VERSION     NM_001398614.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 7286)
  AUTHORS   Tsotsokou,G., Miliou,A., Trompoukis,G., Leontiadis,L.J. and
            Papatheodoropoulos,C.
  TITLE     Region-Related Differences in Short-Term Synaptic Plasticity and
            Synaptotagmin-7 in the Male and Female Hippocampus of a Rat Model
            of Fragile X Syndrome
  JOURNAL   Int J Mol Sci 25 (13), 6975 (2024)
   PUBMED   39000085
  REMARK    GeneRIF: Region-Related Differences in Short-Term Synaptic
            Plasticity and Synaptotagmin-7 in the Male and Female Hippocampus
            of a Rat Model of Fragile X Syndrome.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7286)
  AUTHORS   Bendahmane,M., Morales,A., Kreutzberger,A.J.B., Schenk,N.A.,
            Mohan,R., Bakshi,S., Philippe,J.M., Zhang,S., Kiessling,V.,
            Tamm,L.K., Giovannucci,D.R., Jenkins,P.M. and Anantharam,A.
  TITLE     Synaptotagmin-7 enhances calcium-sensing of chromaffin cell
            granules and slows discharge of granule cargos
  JOURNAL   J Neurochem 154 (6), 598-617 (2020)
   PUBMED   32058590
  REMARK    GeneRIF: Synaptotagmin-7 enhances calcium-sensing of chromaffin
            cell granules and slows discharge of granule cargos.
REFERENCE   3  (bases 1 to 7286)
  AUTHORS   Li,Y.C., Chanaday,N.L., Xu,W. and Kavalali,E.T.
  TITLE     Synaptotagmin-1- and Synaptotagmin-7-Dependent Fusion Mechanisms
            Target Synaptic Vesicles to Kinetically Distinct Endocytic Pathways
  JOURNAL   Neuron 93 (3), 616-631 (2017)
   PUBMED   28111077
  REMARK    GeneRIF: The slowed endocytosis phenotype previously reported after
            syt1 loss of function can also be triggered by other manipulations
            that promote asynchronous release such as Sr(2+) substitution and
            complexin loss of function. The link between asynchronous release
            and slowed endocytosis was due to selective targeting of fused
            synaptic vesicles toward slow retrieval by the asynchronous release
            Ca(2+) sensor synaptotagmin-7.
REFERENCE   4  (bases 1 to 7286)
  AUTHORS   Tratnjek,L., Zivin,M. and Glavan,G.
  TITLE     Synaptotagmin 7 and SYNCRIP proteins are ubiquitously expressed in
            the rat brain and co-localize in Purkinje neurons
  JOURNAL   J Chem Neuroanat 79, 12-21 (2017)
   PUBMED   27771350
  REMARK    GeneRIF: In somata of Purkinje neurons in the cerebellar cortex,
            both SYT7 (and SYNCRIP) were expressed and co-localized.
REFERENCE   5  (bases 1 to 7286)
  AUTHORS   Jackman,S.L., Turecek,J., Belinsky,J.E. and Regehr,W.G.
  TITLE     The calcium sensor synaptotagmin 7 is required for synaptic
            facilitation
  JOURNAL   Nature 529 (7584), 88-91 (2016)
   PUBMED   26738595
REFERENCE   6  (bases 1 to 7286)
  AUTHORS   Reddy,A., Caler,E.V. and Andrews,N.W.
  TITLE     Plasma membrane repair is mediated by Ca(2+)-regulated exocytosis
            of lysosomes
  JOURNAL   Cell 106 (2), 157-169 (2001)
   PUBMED   11511344
REFERENCE   7  (bases 1 to 7286)
  AUTHORS   Sugita,S., Han,W., Butz,S., Liu,X., Fernandez-Chacon,R., Lao,Y. and
            Sudhof,T.C.
  TITLE     Synaptotagmin VII as a plasma membrane Ca(2+) sensor in exocytosis
  JOURNAL   Neuron 30 (2), 459-473 (2001)
   PUBMED   11395007
REFERENCE   8  (bases 1 to 7286)
  AUTHORS   Martinez,I., Chakrabarti,S., Hellevik,T., Morehead,J., Fowler,K.
            and Andrews,N.W.
  TITLE     Synaptotagmin VII regulates Ca(2+)-dependent exocytosis of
            lysosomes in fibroblasts
  JOURNAL   J Cell Biol 148 (6), 1141-1149 (2000)
   PUBMED   10725327
REFERENCE   9  (bases 1 to 7286)
  AUTHORS   Craxton,M. and Goedert,M.
  TITLE     Alternative splicing of synaptotagmins involving transmembrane exon
            skipping
  JOURNAL   FEBS Lett 460 (3), 417-422 (1999)
   PUBMED   10556508
REFERENCE   10 (bases 1 to 7286)
  AUTHORS   Li,C., Ullrich,B., Zhang,J.Z., Anderson,R.G., Brose,N. and
            Sudhof,T.C.
  TITLE     Ca(2+)-dependent and -independent activities of neural and
            non-neural synaptotagmins
  JOURNAL   Nature 375 (6532), 594-599 (1995)
   PUBMED   7791877
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Dec 20, 2021 this sequence version replaced XM_006231065.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF336855.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760433
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-424               JAXUCZ010000001.1  216456259-216456682
            425-528             JAXUCZ010000001.1  216479746-216479849
            529-608             JAXUCZ010000001.1  216484006-216484085
            609-740             JAXUCZ010000001.1  216487708-216487839
            741-968             JAXUCZ010000001.1  216488739-216488966
            969-1337            JAXUCZ010000001.1  216492146-216492514
            1338-1460           JAXUCZ010000001.1  216496294-216496416
            1461-1596           JAXUCZ010000001.1  216501531-216501666
            1597-1867           JAXUCZ010000001.1  216505168-216505438
            1868-2037           JAXUCZ010000001.1  216508900-216509069
            2038-2152           JAXUCZ010000001.1  216509506-216509620
            2153-2352           JAXUCZ010000001.1  216510141-216510340
            2353-7286           JAXUCZ010000001.1  216513785-216518718
FEATURES             Location/Qualifiers
     source          1..7286
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..7286
                     /gene="Syt7"
                     /gene_synonym="SytVII"
                     /note="synaptotagmin 7"
                     /db_xref="GeneID:59267"
                     /db_xref="RGD:62013"
     exon            1..424
                     /gene="Syt7"
                     /gene_synonym="SytVII"
                     /inference="alignment:Splign:2.1.0"
     CDS             394..2457
                     /gene="Syt7"
                     /gene_synonym="SytVII"
                     /note="isoform 1 is encoded by transcript variant 1;
                     synaptotagmin VII; protein Syt7"
                     /codon_start=1
                     /product="synaptotagmin-7 isoform 1"
                     /protein_id="NP_001385543.1"
                     /db_xref="GeneID:59267"
                     /db_xref="RGD:62013"
                     /translation="MYRDPEAASPGAPTRDVLLVSAIITVSLSVTIVLCGLCHWCQRK
                     LGKRYKNSLETVGTPDSGRGRGEKKAINDLDRDFWNNNESTVQQKWSSYPPKEFILNI
                     SPYAPYGDPRLSLNGTLLSGAKVATAAAGLAVEREGRLGEKPAPVPPPGEDALRSGGA
                     APSEPGSSGKAGRGRWRMVQSHLAAGKLNLSNFEDSTLSTATTLESIPSSAGEPKCQR
                     PRTLMRQQSLQQPLSQNQRGRQPSQPTTSQSLGQLQAHAASAPGSNPRAYGRGQARQG
                     TSAGSKYRAAGGRSRSNPGSWDHVVGQIRNRGLDMKSFLEGRMVVLSLVLGLSEQDDF
                     ANIPDLQNPGTQQNQNAQGDKRLPAGGKAVNTAPVPGQTPHDESDRRTEPRSSVSDLV
                     NSLTSEMLMLSPGSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTVKVMKAQELPAKD
                     FSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVL
                     DYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDLKPCSDGSGSRGELLLSLCYNPSANS
                     IIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTKKRNLNPIFNESFAFD
                     IPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQPVAQW
                     HQLKA"
     exon            425..528
                     /gene="Syt7"
                     /gene_synonym="SytVII"
                     /inference="alignment:Splign:2.1.0"
     exon            529..608
                     /gene="Syt7"
                     /gene_synonym="SytVII"
                     /inference="alignment:Splign:2.1.0"
     exon            609..740
                     /gene="Syt7"
                     /gene_synonym="SytVII"
                     /inference="alignment:Splign:2.1.0"
     exon            741..968
                     /gene="Syt7"
                     /gene_synonym="SytVII"
                     /inference="alignment:Splign:2.1.0"
     exon            969..1337
                     /gene="Syt7"
                     /gene_synonym="SytVII"
                     /inference="alignment:Splign:2.1.0"
     exon            1338..1460
                     /gene="Syt7"
                     /gene_synonym="SytVII"
                     /inference="alignment:Splign:2.1.0"
     exon            1461..1596
                     /gene="Syt7"
                     /gene_synonym="SytVII"
                     /inference="alignment:Splign:2.1.0"
     exon            1597..1867
                     /gene="Syt7"
                     /gene_synonym="SytVII"
                     /inference="alignment:Splign:2.1.0"
     exon            1868..2037
                     /gene="Syt7"
                     /gene_synonym="SytVII"
                     /inference="alignment:Splign:2.1.0"
     exon            2038..2152
                     /gene="Syt7"
                     /gene_synonym="SytVII"
                     /inference="alignment:Splign:2.1.0"
     exon            2153..2352
                     /gene="Syt7"
                     /gene_synonym="SytVII"
                     /inference="alignment:Splign:2.1.0"
     exon            2353..7286
                     /gene="Syt7"
                     /gene_synonym="SytVII"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcacacacac atacacacac acacatacac acattcactc acacacacac acgcacacac
       61 atacacacac acacatacac atacacacac acacacacac acaccgcctc gtacacactc
      121 acacacgctc cggcgcgcac acgcggcgcg caggccagag ggaggaggct ccgcgcggct
      181 cggcggcggc ggcagcgtgc tccgcgggcg gcccggaggg ctggcgggcg gcccccgctc
      241 cccggctccg cggctccgtg caacccgcgc ggcccccgcc ctcggacccg cccccggggg
      301 tcgcccggcc ccatgccctg cagcggcggc agagaagcgc gcggccgcag gcggctctga
      361 ggagcccgga gagagccggc gacgaagggg accatgtacc gggacccgga ggcggccagc
      421 ccaggggcac ccacccgcga tgtcctgctg gtctctgcaa tcatcaccgt cagccttagc
      481 gtcactatcg tcctctgcgg cctgtgccac tggtgtcagc gcaaactggg caaacgctac
      541 aagaactcct tggagacggt gggcacgcca gactcggggc gtgggcgcgg tgagaagaaa
      601 gccatcaacg acctagacag agacttttgg aataacaatg aaagcacagt gcagcagaaa
      661 tggagttcct atcctcccaa ggagtttatt ctaaacattt caccctacgc cccttatggc
      721 gaccctcgac tgtccctcaa tggcacactc ctgtcaggcg ccaaagtggc cactgcggcg
      781 gcggggctgg cggtggagcg ggaaggccgg ctcggggaga agccggcgcc ggtgccacca
      841 cccggagagg acgccttgag aagcggcggg gctgccccca gcgagccggg cagcagtggc
      901 aaggcgggga gaggccgctg gcggatggtg cagagccacc tggccgcagg gaagctcaac
      961 ttgtccaatt tcgaggactc caccctgtcc acggccacta cccttgagtc tatccccagc
     1021 tccgcgggag agccgaaatg ccagcgaccc cgcacactga tgcggcagca gagcctgcaa
     1081 cagccgctga gccagaacca gcggggccga cagcccagtc agcccaccac cagccagagc
     1141 ctgggccagc tgcaggccca cgcggcctcg gcaccgggct ccaacccccg ggcctatggt
     1201 cgaggtcagg ctcggcaggg cacctcggcc ggctccaagt accgggcagc tgggggccgc
     1261 agccgctcca acccaggcag ctgggaccac gtggtggggc agattcgaaa ccgaggcttg
     1321 gacatgaaat ccttcctgga aggccggatg gtggtgctat ccctggtatt agggctttcg
     1381 gaacaggatg actttgccaa tatccctgac ctgcaaaacc caggaaccca gcagaaccag
     1441 aacgctcagg gggacaagag gttgcctgca ggagggaagg ctgtgaatac agccccagtg
     1501 cccggccaga cgccacatga tgagtctgac cgcagaacgg agccccgttc ctctgtctcg
     1561 gacctcgtca actcccttac cagcgagatg ctcatgctct ccccaggctc cgaggaggat
     1621 gaggcccatg agggctgcag ccgagagaac ctgggccgaa tccagttcag tgttggctac
     1681 aacttccagg agtccacact caccgtgaaa gtcatgaagg cccaggagct gccggccaag
     1741 gacttcagtg gcactagtga cccctttgtc aagatctacc tactacccga caagaagcac
     1801 aaactggaga ccaaggtgaa acggaagaat ctaaacccgc actggaacga gacctttcta
     1861 tttgaagggt ttccctatga gaaagtggta cagaggatcc tctacctcca ggtcctggat
     1921 tatgaccgtt tcagccgcaa tgaccccatt ggggaggtgt ccatccctct caacaaggtg
     1981 gacctgaccc agatgcagac cttctggaag gatctgaagc catgcagcga tgggagtggg
     2041 agccgagggg agctgctctt gtctctctgc tacaacccct ctgccaactc catcatcgtg
     2101 aacatcatca aagctcgcaa cctcaaagcc atggacatcg ggggcacatc agacccctat
     2161 gtgaaggtgt ggctgatgta taaagacaag cgggtagaga aaaagaagac ggtgacaaag
     2221 aagaggaacc tgaatcccat cttcaatgag tctttcgcct ttgacatacc cacggagaag
     2281 ctgagggaga ccaccatcat catcactgtc atggacaaag acaagctcag ccgcaatgac
     2341 gtcattggca agatctacct gtcctggaag agcggaccag gcgaggtgaa gcactggaaa
     2401 gacatgatcg ctcgtccccg gcagcctgtg gcccagtggc accagctgaa agcctgagag
     2461 gggccgaggg aggccccgag ggccaaggcc tggctcccca tcacgcccta ccactttatg
     2521 cacaatgccc agcccggccc cctgccatgg gtgaggggag aaccccgagc gctcagccag
     2581 ggaagggtac cagaactcta ctgggcccca tttctaggaa gtaccagccc cacctccgtg
     2641 agtccagctc gggagtggga gctctgggag ccatttccct gctttgcctc tttctttcct
     2701 gatttgctga tactaaagac gtgggggaca gctcaagagc cagatgggca gatccctcca
     2761 gaggcccgcc aggtgggcgt agcccccgtt ttctttaagg cagtgcctgg agtggagaga
     2821 agccacccct tccctagccc ccctttttgg ggcccagaag aggaaggccg aggcgtttgg
     2881 cctcggcctg gtcatcaggc ccatccccag cttcaggtgc cgactgggcc ctggacactg
     2941 agggtagtat atagcctgtg ctccagattc ctggaggcgt ggccctgtgt atttgtgttg
     3001 tgtctactgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgcccac atgcgtgtac
     3061 acatgtgcac ctggaagctc atgcgcacat gtgtgaaagg gggtgctccc tccctgtccc
     3121 cctggggcca gccagcagtg ctgattggct atggagaata gcagagtttc ttgaggagga
     3181 agtggggctg ggtcaggcag aggtcaaggc cacagggaag gtaggagaag aagggtatgg
     3241 acagctgaga agtggggacc agggcaggtg gctgtttcag ctgcctcctg gcgcccactt
     3301 tgcctgtctc tgtagccccc acccccacag ctccccggta gaactcccca ctgcagtgtc
     3361 attccttggg cctgggctca cactttgtag gcacctactc accgtgtgca tggccttcca
     3421 acagggcacc actcccatcc ttctcaggca tccctacccc tcacctgggg accccaccct
     3481 cccagatctc atattgcagc caaattggcg tctgctccac actctctggc ttggatacag
     3541 cccctgaccc ccacccctta ccccgacacc tctgcctttt ctttacataa tctgatcaac
     3601 ccctgggctt ctccaggctg tcttgacaca taccccaccc caatcccaga gtagtagctc
     3661 tttttgcccc tcccacccac cgtgtaagca aaggaaacag gggacattcc aggagtctga
     3721 ggttgctata cccaaagaag ctgccgtttc ttctcccagc ctctgctgag actagaactg
     3781 gcttcccctt ggaaacagca gactccagaa tgatccctct taagtcccgt cacctctgtg
     3841 ctgtattgaa aaaaagaccc aactgggcaa agagtctcaa aaccaattca gtgacttgag
     3901 cccaacattc ccagattcga ccaccaggtg gcaccagagc actacatcta tggtggcagt
     3961 tggggaccac agttacggtt ctaccctggc tggcaacttg gcaccccaag gatggaaggg
     4021 gtctggactg gatctgcatg tctagagcac agtgggagca gaggcatttg ggcattttta
     4081 aattccttca gcgggcttcc ccttaccgct caactttctg gctggggtga gatctccttt
     4141 tgttcatatg aaaatgttct tatcagattt tacaccctgt ccccaggagg agtctcttaa
     4201 gtagtaggtg aatcatttgt agagtgaata attccattgt gaaacaaata gttacccaca
     4261 ttacttgtaa atctaaatgt ttgtagactg cagctttcgc tttaggtagg atctccccca
     4321 actcccctgc ccagctgggt gtagcccctg gcaagggctc ctcccaaccc cctgcagagg
     4381 ctgtgtggaa atagaagagg gtgatgtagg aagtctggga gtttggagag aagttgctgc
     4441 catccttccc tccatctgcc tcggtctcct gagtacttcc acagagccat ctgagggacc
     4501 cgggcaactt gcaccagtag gtgtaaggct ggcatcagat ttatgcaggg ctcgctcatg
     4561 cacctcctag ccagtcagct cagagagcat cccctacaga gctgtcctcc cctcaagcta
     4621 ctaggaatag tagtgaccca acctgggatt cttcagcccc cacgtgtagg tggagtgggg
     4681 gggggtgcca gcaagaggct tcaaactgtg ggctgagagc agagtggggt tgcacaagtc
     4741 gcagctggat gatggagtct gggcctacga tggttaaggg agggcaactg gaggaacatg
     4801 gaaacggggg agggggggaa gacttgaggg tgaggagagc accagggctc tgccactaat
     4861 gtcctaggat gttgggcaag tcacccacac tccctgggcc tcagtttctc catctgtaaa
     4921 atgatggtaa taatacttca cctacctcat gggggaggtt gtgaggccac catcacctga
     4981 ccaaggggat caaggcagga ggggctctga aggtgctacc cagagcaaag ttgttgctga
     5041 cgcctgaaag caaggccacc tgcccgtcca ccctacccca cagagcctct agggaccgcc
     5101 agagccaatc tgtctcttca ctgtgtccca acccccttta agagcatcat ctgacatctt
     5161 gtgggcaccc tagactagtt gttatgttgt ttaggtagcc tttcctgtga ccatcttctt
     5221 tgtgtaactg ctatacaatt ccacctgccc cagcacaccc ctccacctgc cctccagcac
     5281 cagaggccag ggaagggaca aaggaaaaca gccacaaaag aaaaaaaaaa aaaaaagcca
     5341 aggggactcc cagctcagct ggaaccccca ggggtgggaa ctggtggcgc tgtttgtatt
     5401 gtgtttgagt ccttgagcgc aagtgtttta taaaaaataa aacaaaaatc cactatcaca
     5461 aaaaaaaaaa agaaaaaaat acagcaaaga gaactgaaga caaaagggaa aaagaaccat
     5521 acgatttttc caccatatgc accctctaag ccagcaaaat tttcctcttt gcaaaatcat
     5581 atttttgtgg gaatgggccc tgctttttgt ggcaaggcct gttctgatta ataaaggatc
     5641 gtgaaaaagt agggccttgg ctgtttcctc tgagggtccc agccctctct ctcttcttcc
     5701 aagggaagca acagctggga ttggagggaa tggggggtct tggggttctc cactcagctt
     5761 gtcacctctg atttttcatc agtgactggg gcctgcctga gctcactctc agatctagac
     5821 taatccccac tacattcacc agctgcccca aagcagagag cattgcatgt cccaggtcag
     5881 acctaaagtc atcttagaag tagtgggaac tccctaagat ctccaagacc tcccttggaa
     5941 tccacttagt tgggcacaca ctctctctct tgccagggaa cccttattac actcccaggt
     6001 cggttgaaaa agcaaagatg ggaccccagc caccatctta ccatcacctc tgctcagctg
     6061 ctatgacttg gggccaatgt ctccttctag gacttggcag gggaaagaaa gaacaggctg
     6121 agctctaggt cagcctgctg gacccatggc ctttctccaa cctattgtct aggctgattt
     6181 tctatggttg gaaaaaaaaa tctctcccat ctaaagagcc ccattggcca gttccaggcc
     6241 gaggacctga gagactccag tgccctcctg tctgtgggtc tggcaagcca tgtctttcgc
     6301 tgtgctctca gtgtcctcga ctcacaaaga agcaataatt tcccagccac tccctgcttg
     6361 gtccagggca gctggcctgc cagttctcag ggtactgcag aaggccaact atatctgctt
     6421 cagataggca ctaagggaac cccataattc catgggccct gccccactct gaagtgaaga
     6481 gggtcacata ccctctgtcc cccacatctg ggggccagca gctgcctcct caacctgtac
     6541 taagtacccc cattctgaag ctgcctaccc tctcctcttc tgccccttta acgtcctaca
     6601 atgtgggtta aaatcccttt ttaaaggtgt acgcaggcta gggtatagct cagaggtaca
     6661 gctcttgccc tactgtgcac aagcatctga cagggggcag aacagtttca gttggcttct
     6721 cttccagaag ttcgagggag tcctgggtca ggtaagtagc ttcagggtca cgctggatat
     6781 ggtttagctt ttctttggga aaataaaccc aagaaacagt tttagcaaag ttggttcagc
     6841 acagcagagg tgccagaccc tggccactgg cacaggacct ctaccctgga cttctgaggc
     6901 tcagtccctc tgcctgctct gagctactca cacatccctt catgtgcctg agaccactct
     6961 ctctcttgca agtccctccc agatgcacta cttctaaagg tctctctgac ctttctggat
     7021 tctgggctct cctctccttc tctgagaaag acagctgagg gataatctga acatgcttca
     7081 tgcccccatc ctgagctgcc cccatctgtt tctcatgaag tcatccactt cccatgtctg
     7141 ggtcctgtgt gtgtctatgt gtctgtggat gcacatgaat gcgagtgtgg tgtctcttag
     7201 attgtgagcc cttgggcagg gttccctgtc tgaatagacg ttctgtgtgg cacgcctggc
     7261 tgtgttaata aatgtccatc ttcaga
//
