LOCUS       NM_001108563            3403 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus synaptophysin-like 2 (Sypl2), mRNA.
ACCESSION   NM_001108563 XM_001071432 XM_342316
VERSION     NM_001108563.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3403)
  AUTHORS   Correll RN, Lynch JM, Schips TG, Prasad V, York AJ, Sargent MA,
            Brochet DXP, Ma J and Molkentin JD.
  TITLE     Mitsugumin 29 regulates t-tubule architecture in the failing heart
  JOURNAL   Sci Rep 7 (1), 5328 (2017)
   PUBMED   28706255
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3403)
  AUTHORS   Chen S, Lu FF, Seeman P and Liu F.
  TITLE     Quantitative proteomic analysis of human substantia nigra in
            Alzheimer's disease, Huntington's disease and Multiple sclerosis
  JOURNAL   Neurochem Res 37 (12), 2805-2813 (2012)
   PUBMED   22926577
REFERENCE   3  (bases 1 to 3403)
  AUTHORS   Satoh K, Akatsu H, Yamamoto T, Kosaka K, Yokota H and Yamada T.
  TITLE     Mitsugumin 29 is transcriptionally induced in senile
            plaque-associated astrocytes
  JOURNAL   Brain Res 1441, 9-16 (2012)
   PUBMED   22290180
REFERENCE   4  (bases 1 to 3403)
  AUTHORS   Kurebayashi N, Takeshima H, Nishi M, Murayama T, Suzuki E and Ogawa
            Y.
  TITLE     Changes in Ca2+ handling in adult MG29-deficient skeletal muscle
  JOURNAL   Biochem Biophys Res Commun 310 (4), 1266-1272 (2003)
   PUBMED   14559251
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473952.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001071432.1, XM_342316.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB158471.1, FQ125367.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06621351 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3403
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..3403
                     /gene="Sypl2"
                     /gene_synonym="Mg29"
                     /note="synaptophysin-like 2"
                     /db_xref="GeneID:362018"
                     /db_xref="RGD:1309907"
     exon            1..236
                     /gene="Sypl2"
                     /gene_synonym="Mg29"
                     /inference="alignment:Splign:2.1.0"
     CDS             183..977
                     /gene="Sypl2"
                     /gene_synonym="Mg29"
                     /note="mitsugumin29"
                     /codon_start=1
                     /product="synaptophysin-like protein 2"
                     /protein_id="NP_001102033.1"
                     /db_xref="GeneID:362018"
                     /db_xref="RGD:1309907"
                     /translation="MSSTESPGRTSDKSPRQQVDRLLLGLRWQRLEEPLGFIKVLQWL
                     FAIFAFGSCGSYSGETGALVRCNNDPKDVSSIIVLFGYPFRLYQVQYEMPLCDEESTS
                     KTMNLMGDFSAPAEFFVTLGIFSFFYTMAALVIYLRFHKVYTENKRFPLVDFCVTVSF
                     TFFWLVAAAAWGKGLTDVKGATRPSSLTAAMSVCHGEEAVCSAGATPSMGLANISVLF
                     GFINFFLWAGNCWFVFKETPWHGQGQDQGQGPSQESAAEQGAVEKQ"
     exon            237..311
                     /gene="Sypl2"
                     /gene_synonym="Mg29"
                     /inference="alignment:Splign:2.1.0"
     exon            312..436
                     /gene="Sypl2"
                     /gene_synonym="Mg29"
                     /inference="alignment:Splign:2.1.0"
     exon            437..638
                     /gene="Sypl2"
                     /gene_synonym="Mg29"
                     /inference="alignment:Splign:2.1.0"
     exon            639..830
                     /gene="Sypl2"
                     /gene_synonym="Mg29"
                     /inference="alignment:Splign:2.1.0"
     exon            831..3403
                     /gene="Sypl2"
                     /gene_synonym="Mg29"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggggcagc gcggcggaca gagcctccga gagcgcgagc agcagcgccc ccacgaccca
       61 gcccgccagc ctggagcccg gcctgcccac ggccgcgagc ccgccgcccc cagcgccccc
      121 gcgcgccccg cagcctcccg gccagggagt cgaacccccg cactgcgccc cgacgcgcca
      181 gcatgtcctc gacggagagc cccggccgca cctcggacaa gtctccgcgc cagcaggtgg
      241 accgcctgct cctggggctg cgctggcagc gcctggagga gccgctgggc ttcatcaaag
      301 ttctccagtg gctctttgct attttcgcct tcgggtcctg cggctcttac agcggggaga
      361 cgggagcctt ggttcgctgc aacaacgacc ccaaggacgt gagctccatc attgttttgt
      421 tcggctatcc cttcaggttg taccaggtcc agtatgagat gcctctctgt gatgaggaat
      481 ccacatccaa aaccatgaac ctcatgggag acttctctgc ccccgccgag ttctttgtga
      541 cccttggcat cttttccttc ttctatacaa tggctgccct ggtcatctac ctgcgcttcc
      601 acaaagtcta cacggagaac aaacgcttcc cattggtgga tttctgtgtg accgtctctt
      661 tcaccttctt ttggctggtt gctgccgctg cctggggcaa gggcttgact gatgtcaaag
      721 gggccacacg gccatccagc ctgactgcag ccatgtctgt gtgccatgga gaggaggcag
      781 tgtgcagtgc tggggccacg ccctctatgg ggctggctaa catctctgtg ctctttggct
      841 ttatcaactt cttcctgtgg gctggaaact gttggtttgt gttcaaagag accccatggc
      901 acggacaagg ccaggaccag ggccagggcc ccagccagga gagtgcagca gaacagggag
      961 cggtggagaa gcagtaagca gccctcatct gcctactccc caactggaca tggacagcac
     1021 cttctcatct cctccagctt ctacaggacc ttcttcctcc tcctcctccc ttaccccatc
     1081 actctggact ttgagatttg agagaatgga tgggtaggca tcagctgttg gtaacctggg
     1141 cagaccccca ctggctatcc ctcatcctgc tggggcagcc aatggcagga tctccgtgct
     1201 tcttgtccgc tgcctggagt tgggcatctt gctcgggcaa gtcagctggc aaccttgccc
     1261 tgattcccgt gtggagggcc caccagtgac tttgtgacat ccctcggtag ctgtcatcta
     1321 atctgtatcc tatctctagc cctcccagag ctcactgtgc tccccaatct cctctctggc
     1381 ctctgtccat agctctcacc acgtgtgaag cagggagacc cattacctta ccgaaggtcc
     1441 ctctaggggt ccacgtgaga cccggaccca gtgggagagg atagagttgc ctattgcagc
     1501 accaaggaag aaagtcagga aagttgctgg cagaatacgt tttctgtccc ctcagccctc
     1561 cctctccctc agctggaaca ctttcagtag tgccctacac tccacttatt catgaaaccc
     1621 cttacaccct tctccttctc agccttggtt ttgtctcaca cttcggaaac aagatggaat
     1681 ggcttggaac atttcccctt cattttccca tccccaccac acctgtgggc ccttctccct
     1741 tccccaacct tttggagatg aggcatttaa gatcttttca aaagcctgcc caggccttcc
     1801 tttcattcct gtgggctttg ggagggcctg aaggaccacc ataaggctga tgtgcccagg
     1861 aatcccagga catgaataca cgggcccagt tgtcccttac tgtctgttca ttttctcaag
     1921 ccagctcctt ttctagttct ttcaaacctg tccttcccat cttaacaaag agggttctct
     1981 ctcctcatct ctcacctcca cacggtagcc aggccccatc ccttccccag tcctgggcag
     2041 cccgatgcta ttggtgcttc ttcacttcgg gacccagttc catatttgtc tttggtgtgt
     2101 ctcctcttcc tgataccccc ttcatcccct ttttgtcccc aaggccttag ggtaccaact
     2161 gggtaaatgc catccgcctc ctacctagat caaaacccct tgatctaccc tggcagggtt
     2221 gctcagggaa agtgaagaag gaagaaacca gccatttccc aatatagtgg caacgggccc
     2281 acctaaatcc caaagatgaa tgtaccttgt gccaacctgt ccttaagaca cgatcaaccc
     2341 tctccagccc ccttgcctct ctcaatgcta cccacatcaa gatgtattac ttgggtgccc
     2401 agggctcaga atccttaact ctgggccatt catttcttct ttgggttaca atttccccac
     2461 ccaacagaga agtatgatat ttacagacat tacagatgct cccaagccct tcagtaaaag
     2521 aatttggaat ttttgttttc tgtttcagat tttagagaaa agatttgaga aggggaaaat
     2581 ttgatgagga tgagaatgtt cctaaatctg aaactctcta tcctaagttg tcctcatggt
     2641 tacttaagga caagggggag agttttgcct acaactttag atatacaaag aacaaagggg
     2701 tgaccatttt tcttcaagca agtccctgtg gggatctggg agcagcttct actcgaactg
     2761 tgtttggatt ctgcgtccat atttataatt tatttgaact gtgatggata cagtgttctc
     2821 atttagggcc taaggtagca actggcccat caactacttt agaaagggag ctgtccactc
     2881 ccagtgagca ctcttactcc agagctctct ctagggttga gaaggctttt cttcagcaag
     2941 agtctggcta tggccaaaag agccttaatt taggctatgg cctttctctc catggctgcc
     3001 ctcagaggaa agaccagttc acctcattac ctccaggggg ctgggcagcc tgcgtgccaa
     3061 gggcagctct gtcctcataa gactcatgtc ctctccaacc agggctggca ccagtacttt
     3121 gtctagtcag gcctggacta ggagaaggtg tctggtttct ctagctatcg caggaggcca
     3181 acaagcgggg aacttgccct ttgccctggt agactctgac catgtggaga tgaccatcta
     3241 ggacctttct tagacatgag ttcccatcaa catcctgatg gtgggtctcc tacttctggg
     3301 attgcagatt gagggcatgg ggagaatgtt gcatgttgtt ttgtggtgct tgttattaca
     3361 cgtttgaata aacagtgctg cgaacagttg tcaagaagaa gcc
//
