LOCUS       NM_053419               4696 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus synergin, gamma (Synrg), mRNA.
ACCESSION   NM_053419 XM_001081085 XM_573165
VERSION     NM_053419.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4696)
  AUTHORS   Saad,Y., Garrett,M.R., Manickavasagam,E., Yerga-Woolwine,S.,
            Farms,P., Radecki,T. and Joe,B.
  TITLE     Fine-mapping and comprehensive transcript analysis reveals
            nonsynonymous variants within a novel 1.17 Mb blood pressure QTL
            region on rat chromosome 10
  JOURNAL   Genomics 89 (3), 343-353 (2007)
   PUBMED   17218081
REFERENCE   2  (bases 1 to 4696)
  AUTHORS   Fernandez-Chacon,R., Achiriloaie,M., Janz,R., Albanesi,J.P. and
            Sudhof,T.C.
  TITLE     SCAMP1 function in endocytosis
  JOURNAL   J Biol Chem 275 (17), 12752-12756 (2000)
   PUBMED   10777571
REFERENCE   3  (bases 1 to 4696)
  AUTHORS   Page,L.J., Sowerby,P.J., Lui,W.W. and Robinson,M.S.
  TITLE     Gamma-synergin: an EH domain-containing protein that interacts with
            gamma-adaptin
  JOURNAL   J Cell Biol 146 (5), 993-1004 (1999)
   PUBMED   10477754
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Oct 25, 2022 this sequence version replaced NM_053419.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EF121981.1, SRR26643296.28010.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-115               JAXUCZ010000010.1  69347113-69347227
            116-156             JAXUCZ010000010.1  69356349-69356389
            157-275             JAXUCZ010000010.1  69361258-69361376
            276-406             JAXUCZ010000010.1  69362843-69362973
            407-512             JAXUCZ010000010.1  69365770-69365875
            513-624             JAXUCZ010000010.1  69366548-69366659
            625-927             JAXUCZ010000010.1  69369695-69369997
            928-1161            JAXUCZ010000010.1  69371264-69371497
            1162-1239           JAXUCZ010000010.1  69372379-69372456
            1240-1436           JAXUCZ010000010.1  69374373-69374569
            1437-1685           JAXUCZ010000010.1  69375428-69375676
            1686-1819           JAXUCZ010000010.1  69379460-69379593
            1820-1932           JAXUCZ010000010.1  69387077-69387189
            1933-1995           JAXUCZ010000010.1  69387424-69387486
            1996-2928           JAXUCZ010000010.1  69392408-69393340
            2929-3291           JAXUCZ010000010.1  69403083-69403445
            3292-3455           JAXUCZ010000010.1  69406272-69406435
            3456-3509           JAXUCZ010000010.1  69407099-69407152
            3510-3606           JAXUCZ010000010.1  69407782-69407878
            3607-3755           JAXUCZ010000010.1  69408968-69409116
            3756-3866           JAXUCZ010000010.1  69426307-69426417
            3867-3902           JAXUCZ010000010.1  69426782-69426817
            3903-4696           JAXUCZ010000010.1  69427921-69428714
FEATURES             Location/Qualifiers
     source          1..4696
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q26"
     gene            1..4696
                     /gene="Synrg"
                     /gene_synonym="Ap1gbp1; Syng"
                     /note="synergin, gamma"
                     /db_xref="GeneID:84479"
                     /db_xref="RGD:620684"
     exon            1..115
                     /gene="Synrg"
                     /gene_synonym="Ap1gbp1; Syng"
                     /inference="alignment:Splign:2.1.0"
     CDS             45..4034
                     /gene="Synrg"
                     /gene_synonym="Ap1gbp1; Syng"
                     /note="AP1 subunit gamma-binding protein 1;
                     gamma-synergin"
                     /codon_start=1
                     /product="synergin gamma"
                     /protein_id="NP_445871.2"
                     /db_xref="GeneID:84479"
                     /db_xref="RGD:620684"
                     /translation="MALRPGAGASGAAGAGTGPGGAGSFMFPVAGGMRPPQGLIPMQQ
                     QGFPMVSVMQPNMQGMMGMNYSSQMSQGPIAMQAGIPMGPMPAAGVPFLGQPPFLGMR
                     PAAPQYTPDMQKQFAEEQQKRFEQQQKLLEEERKRRQFEEQKQKLRLLSSVKPKTGEK
                     NRDDALEAIKGNLDGFSRDAKMHPTPASHPKKPDCPTSSHSTKTVSPSSAFLGEDEFS
                     GFMQGPVELPTCGPSSTAQPFQSFLPSTPLGQLHTQKAGAQPLPPGQAPVSFAVHGVH
                     GQIPCLSAASASHSVQKAGPSLEEKLLVSCDISASGQEHIKLSSPEAGHRAVVPGSSK
                     NSPGLMAHNGGAVDGCVSGPTTAVAEKTSDQNLSKEESGVGVFPSQDPVQPRMPPWIY
                     NESLVPDAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTK
                     EELYTVLAMVAVTQRGVPAMSPDTLNQFPAAPIPTLSGFPMTLPTPVSQPTAMTSGPA
                     GSIPLSLGQPIMGINLVGPVGGAAAPTSSGFMPAYPSNQVGKTEEDDFQDFQDASKSG
                     SIDDSFTDFQEVPASSKTSNSQHGNSAPSLLIPLPGTKASTDKYAVFKGISAEKPSEN
                     PASFGESGDKYSAFRELEPTADSKPLGESFAEFRSTGTDDGFTDFKTADSVSPLEPPT
                     KDSFPSAFASGAAQQTQTQVKTPLNLADLDMFSSVDCSGEKPVPFSAAFSTSKSVSSR
                     PQPAGSAAAPASLASTKASSLADDFGEFNLFGEYSNPASVGEQDDFADFMAFGNSSIP
                     SEPKADDKYEALREEGSPGALSTSTVEGAHNPPVSSSKYDVFKQLSLEGAGLAIEEFK
                     ENTPSTKSDGDFADFHSSKFSSTSSDKSLGEKAVAFRHAKEDSASVKSLDLPSIGGSS
                     VGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVSGQHPPAAGSALASEDALP
                     ETPFPAFASFKDMMPQTTEQKEYETGDFQDFTRQDMPMVDRSQENTCPSPASSVASHE
                     TPKEGADDFGEFQSEKPKISKFDFLVANSQSKMKSSEEMIKSELATFDLSVQGSHKRS
                     LSLGDKEISRSSPSPALEQPFRDRSNTLSERAALPVIRDKYKDLTGEVEENERYAYEW
                     QRCLGSALDVIKKANDTLNGISSSAVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIK
                     ATAVCSEKLQQLLKDIDKVWNNLIGFMSLTTLTPDENSLDFSSCMLRPGIKNAQELAC
                     GVCLLNVDSRSRKEETPAEEQPKKAFNSETDSFKLAYGGHQYHASCANFWINCVEPKP
                     PGLLLPDLL"
     exon            116..156
                     /gene="Synrg"
                     /gene_synonym="Ap1gbp1; Syng"
                     /inference="alignment:Splign:2.1.0"
     exon            157..275
                     /gene="Synrg"
                     /gene_synonym="Ap1gbp1; Syng"
                     /inference="alignment:Splign:2.1.0"
     exon            276..406
                     /gene="Synrg"
                     /gene_synonym="Ap1gbp1; Syng"
                     /inference="alignment:Splign:2.1.0"
     exon            407..512
                     /gene="Synrg"
                     /gene_synonym="Ap1gbp1; Syng"
                     /inference="alignment:Splign:2.1.0"
     exon            513..624
                     /gene="Synrg"
                     /gene_synonym="Ap1gbp1; Syng"
                     /inference="alignment:Splign:2.1.0"
     exon            625..927
                     /gene="Synrg"
                     /gene_synonym="Ap1gbp1; Syng"
                     /inference="alignment:Splign:2.1.0"
     exon            928..1161
                     /gene="Synrg"
                     /gene_synonym="Ap1gbp1; Syng"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1239
                     /gene="Synrg"
                     /gene_synonym="Ap1gbp1; Syng"
                     /inference="alignment:Splign:2.1.0"
     exon            1240..1436
                     /gene="Synrg"
                     /gene_synonym="Ap1gbp1; Syng"
                     /inference="alignment:Splign:2.1.0"
     exon            1437..1685
                     /gene="Synrg"
                     /gene_synonym="Ap1gbp1; Syng"
                     /inference="alignment:Splign:2.1.0"
     exon            1686..1819
                     /gene="Synrg"
                     /gene_synonym="Ap1gbp1; Syng"
                     /inference="alignment:Splign:2.1.0"
     exon            1820..1932
                     /gene="Synrg"
                     /gene_synonym="Ap1gbp1; Syng"
                     /inference="alignment:Splign:2.1.0"
     exon            1933..1995
                     /gene="Synrg"
                     /gene_synonym="Ap1gbp1; Syng"
                     /inference="alignment:Splign:2.1.0"
     exon            1996..2928
                     /gene="Synrg"
                     /gene_synonym="Ap1gbp1; Syng"
                     /inference="alignment:Splign:2.1.0"
     exon            2929..3291
                     /gene="Synrg"
                     /gene_synonym="Ap1gbp1; Syng"
                     /inference="alignment:Splign:2.1.0"
     exon            3292..3455
                     /gene="Synrg"
                     /gene_synonym="Ap1gbp1; Syng"
                     /inference="alignment:Splign:2.1.0"
     exon            3456..3509
                     /gene="Synrg"
                     /gene_synonym="Ap1gbp1; Syng"
                     /inference="alignment:Splign:2.1.0"
     exon            3510..3606
                     /gene="Synrg"
                     /gene_synonym="Ap1gbp1; Syng"
                     /inference="alignment:Splign:2.1.0"
     exon            3607..3755
                     /gene="Synrg"
                     /gene_synonym="Ap1gbp1; Syng"
                     /inference="alignment:Splign:2.1.0"
     exon            3756..3866
                     /gene="Synrg"
                     /gene_synonym="Ap1gbp1; Syng"
                     /inference="alignment:Splign:2.1.0"
     exon            3867..3902
                     /gene="Synrg"
                     /gene_synonym="Ap1gbp1; Syng"
                     /inference="alignment:Splign:2.1.0"
     exon            3903..4696
                     /gene="Synrg"
                     /gene_synonym="Ap1gbp1; Syng"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcttcggct gacagctgct ggcgcggtgg cggccccgag caagatggcg ctgcggccgg
       61 gagccggagc cagcggcgcg gcgggggcgg gcacagggcc cggcggggca ggcagcttca
      121 tgtttcctgt cgcaggtggc atgagacccc ctcaaggcct gattccaatg cagcagcaag
      181 gatttcctat ggtctctgtc atgcagccca atatgcaagg catgatggga atgaattaca
      241 gctctcagat gtcccaggga cccattgcaa tgcaggcagg aataccaatg gggccaatgc
      301 cagcagcggg tgtacctttc ctgggtcagc caccttttct gggcatgcgt cctgcagccc
      361 cacagtacac tccagacatg cagaagcagt ttgcggaaga gcaacaaaaa cgatttgaac
      421 aacaacaaaa gctcttagaa gaagaaagaa aacgacgtca gtttgaagag caaaaacaaa
      481 agctcagact tctgagtagc gtgaaaccca agacaggaga gaagaacaga gacgacgctt
      541 tggaagccat caaaggaaac ttggatgggt tttccagaga tgctaagatg caccccactc
      601 ccgcatctca cccaaagaaa ccagactgcc ccacatcatc tcattctact aaaactgtct
      661 ccccgtcatc tgcctttctt ggtgaagatg aattcagtgg ctttatgcag gggcctgttg
      721 agcttcccac ttgtgggcct tcttccacag cccagccctt tcagtctttc ctccccagca
      781 ccccactcgg ccagttacac acacagaagg ctggggcaca gcctctacct ccaggtcagg
      841 ctccagtgtc ttttgccgta catggtgtcc atgggcaaat tccttgttta tctgctgctt
      901 cagcttccca cagtgtgcag aaagcaggcc cttccttgga agagaagctc ctagtatctt
      961 gtgatataag tgcatctggg caggaacaca ttaaattaag ctctcctgaa gctgggcaca
     1021 gagccgtagt cccaggttcc agtaagaact ctcccggttt aatggcccat aacgggggtg
     1081 ctgtagatgg atgtgtgagt ggtcccacca ctgcagtcgc agaaaagact tcagatcaaa
     1141 acctgtcaaa ggaagagagt ggtgtgggcg tgtttccctc tcaggatcct gttcagccca
     1201 gaatgcctcc ttggatttac aatgagagtt tggttccaga tgcttataag aaaattttag
     1261 aaaccacaat gactccaacc ggaatagaca ctgctaaact ttatcccatt ctgatgtcat
     1321 ctggacttcc cagggaaact cttggacaga tatgggcctt agctaatcga actacgcctg
     1381 gcaagctcac taaggaggag ctttacaccg ttctcgccat ggtagcagta acacagagag
     1441 gtgttcctgc catgagccct gatactttga accagttccc tgcggctccc attcctacct
     1501 taagcggctt tcctatgact ctgcctaccc cagtgagcca gccaacagcg atgacctctg
     1561 gccccgcagg ctccataccc ctcagccttg gacagcccat catgggcatt aaccttgttg
     1621 gaccagtggg tggagctgca gcgccaactt ccagtggctt catgccagcc tacccctcaa
     1681 accaggtggg aaagacagaa gaagatgact tccaggattt tcaagatgct tcgaagtcag
     1741 gatccatcga tgattctttc actgacttcc aagaggtgcc tgcgtcctca aaaaccagta
     1801 attcccagca tggaaacagt gctccctcac tcttgatccc acttcctgga actaaagcct
     1861 ccacagacaa atatgcagtg tttaaaggga tttctgctga gaagccctct gaaaaccctg
     1921 cttcatttgg agagtccggt gataaataca gtgctttcag ggaactcgag ccaacagcag
     1981 acagtaagcc tttaggagag agctttgcgg agttcagatc cacaggaacc gatgacggct
     2041 tcactgactt caagactgct gatagtgtgt cacccctaga gccaccaaca aaagactctt
     2101 ttccatcggc ctttgcctca ggagctgcac agcagacaca gacacaggtg aaaactcctc
     2161 tgaacttagc agacctagat atgttctcct cagtggattg cagtggggag aaaccagtgc
     2221 ccttttcagc tgcatttagc acctcaaagt cagtttcctc aagacctcag ccggcgggtt
     2281 ctgcagcagc cccagcatca ctggcatcca ctaaagcgtc cagtttggca gatgattttg
     2341 gagagttcaa cctctttggg gaatattcga accctgcgtc tgttggggag caggacgact
     2401 ttgcagattt catggctttc ggtaacagct ccatcccctc tgagccaaaa gcagatgaca
     2461 agtatgaagc cctcagagaa gaagggagcc ccggcgcctt gtccaccagc actgtggagg
     2521 gtgcacacaa cccacctgtt tcgtcatcca agtacgacgt cttcaaacag ctttccctag
     2581 agggagctgg actggccatc gaggagttca aagagaacac tccttccaca aagagtgacg
     2641 gtgactttgc tgacttccac tccagtaaat tctcatccac gagctcagac aaatccctgg
     2701 gagagaaagc agtggctttc agacatgcca aagaagactc cgcctcggtg aagtctttag
     2761 acctcccctc catcggtggc agcagtgttg gcaaggagga ctctgaagat gcgctttctg
     2821 ttcagtttga catgaagttg gctgatgtag gaggagatct taagcatgtc atgtctgata
     2881 gctctttgga tttaccaaca gttagtggcc aacatcctcc tgccgcagga tcagccttgg
     2941 ccagtgagga cgctcttcca gagactccct tcccagcttt tgccagcttt aaagacatga
     3001 tgccccagac cactgagcag aaagagtatg aaactgggga cttccaggat ttcacaaggc
     3061 aggacatgcc catggtggac cggagccaag agaacacatg tcccagccca gcttccagtg
     3121 tggcctcgca cgaaaccccc aaggagggtg cagacgactt tggagaattt caaagtgaaa
     3181 agcccaaaat cagcaagttt gactttttag tagctaattc acagagcaaa atgaagtcta
     3241 gtgaagaaat gatcaaaagt gagctggcaa cctttgacct ttctgttcaa ggatcacaca
     3301 agaggagctt gagccttggg gataaagaaa taagcaggtc ctctccttcc ccggccctgg
     3361 agcagccctt cagagaccgg tccaacactc tgagtgagag agctgcactg cccgtcatcc
     3421 gagacaagta caaggatctg actggcgaag tggaggaaaa tgagagatac gcgtatgagt
     3481 ggcagagatg cctggggagc gccctggatg tcattaagaa ggcaaacgac accttaaacg
     3541 gcattagcag cagtgctgtc tgcacagaag ttatccagtc agcccaaggc atggagtatc
     3601 tcctaggcgt ggtggaagtg taccgagtaa ccaagcgcgt ggagctgggg atcaaagcca
     3661 ctgctgtgtg tagtgagaaa ctccagcagt tgctgaagga catcgataaa gtgtggaaca
     3721 acttaatcgg cttcatgtca cttaccacac tcacgccaga tgagaattca ctggattttt
     3781 cctcctgtat gttacggcct gggatcaaaa acgcccagga gctggcttgt ggagtgtgtc
     3841 tcctaaatgt ggactccaga agccggaaag aagagacacc tgcagaagaa cagcctaaaa
     3901 aagcattcaa ctcagaaaca gacagtttca agctggccta tgggggacat cagtaccacg
     3961 ccagctgtgc caacttctgg atcaactgtg ttgaacccaa gcctcccggc ctcctcttgc
     4021 cagatctgct ctgaaaagct gctcagtgaa gctgattttg ggttgattct gtcacaggac
     4081 ttagggtgac agggatcaat aaatagaatg cagtactgca gagcccctcc caccggtctc
     4141 tttgccgcat tccccaggag gcaggctgca aagctgcagt ggagggcccc accacaaaac
     4201 cttccatcac tacttcagcc tgccgctctt tgagacttga ggtaaactat tggacccgaa
     4261 ctgcacgtgg cactggacac ttgcttgctt atctcctctg gcgttgttgt tgttgatggt
     4321 gatgttggtt tgatttccct ttttaaaacc agggccttgg tgcacccccc tggctgacct
     4381 tgaatctgca ttgatttccc atgtttgcct cctaagtgct ggcccacagg catgggccac
     4441 cataccgttt ctcttgtcct ctcaagttaa tttaaaatga agatcagagt tttctgtgag
     4501 gggtaatctg ctgctgaatt gtatgtgaaa cgttaacaag agaagaaaag taagttctgc
     4561 caggaccaga atccacaagt ttgtctccag ccggcactcg ctcatgtccg gcaatgtggc
     4621 cccaggaagc aggacacatt ttttctgcat ttagcttttt aatacttgaa gtgaataaaa
     4681 aaggcttgtg attaaa
//
