LOCUS       NM_001305138            4462 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus synaptopodin 2-like (Synpo2l), transcript variant
            1, mRNA.
ACCESSION   NM_001305138 XM_223791
VERSION     NM_001305138.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4462)
  AUTHORS   van Eldik W, den Adel B, Monshouwer-Kloots J, Salvatori D, Maas S,
            van der Made I, Creemers EE, Frank D, Frey N, Boontje N, van der
            Velden J, Steendijk P, Mummery C, Passier R and Beqqali A.
  TITLE     Z-disc protein CHAPb induces cardiomyopathy and contractile
            dysfunction in the postnatal heart
  JOURNAL   PLoS One 12 (12), e0189139 (2017)
   PUBMED   29206857
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4462)
  AUTHORS   Beqqali A, Monshouwer-Kloots J, Monteiro R, Welling M, Bakkers J,
            Ehler E, Verkleij A, Mummery C and Passier R.
  TITLE     CHAP is a newly identified Z-disc protein essential for heart and
            skeletal muscle function
  JOURNAL   J Cell Sci 123 (Pt 7), 1141-1150 (2010)
   PUBMED   20215401
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000255.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001305138.3.
            
            On Feb 10, 2021 this sequence version replaced NM_001305138.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments and orthologous data.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760384,
                              SAMEA5760386 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-105               JACYVU010000255.1  3631974-3632078
            106-257             JACYVU010000255.1  3633281-3633432
            258-772             JACYVU010000255.1  3633790-3634304
            773-4462            JACYVU010000255.1  3637740-3641429
FEATURES             Location/Qualifiers
     source          1..4462
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p16"
     gene            1..4462
                     /gene="Synpo2l"
                     /gene_synonym="RGD1565434"
                     /note="synaptopodin 2-like"
                     /db_xref="GeneID:305675"
                     /db_xref="RGD:1565434"
     CDS             1..2937
                     /gene="Synpo2l"
                     /gene_synonym="RGD1565434"
                     /note="isoform 1 is encoded by transcript variant 1;
                     synaptopodin 2-like protein"
                     /codon_start=1
                     /product="synaptopodin 2-like protein isoform 1"
                     /protein_id="NP_001292067.1"
                     /db_xref="GeneID:305675"
                     /db_xref="RGD:1565434"
                     /translation="MGAEEEVQVTLAGGAPWGFRLQGGAEQRKPLQVSKIRRRSQAGR
                     SGLRERDQLLSINGVSCTDFSHASAMTLIDASGHQLVLTVRRVAEEGSVRSPSPGELQ
                     MLSPLSPLSPEPPGAPVTQAPQPGSLRSPPDSEAYYGETDSDVDGPATHEKPRRTRRR
                     GPPRPSLPGAPPDEVYLSDSPAEPAPVKTGSPSQGDSRVSSPSWEEGSALQPPPAEAL
                     LLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQAKLQRAESLQEKSVKEAKTK
                     CRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGTEEEEDGIPPTSES
                     ELDEEAFSDARSLTNQSDWDSPYLDMELARAGSGIAESQSSGLGGQLSEVSGRGVQLF
                     EQQRQRVASSSQELAQVGPAAMLNGQSLQSPPRAQSAPPEAAVLPLSPLSAPAASPSP
                     FQDGGAPSPAPSIFNRSARPFTPGLPGQRSGTTSVIFRPVAPKKVNEALGGTSPAPSP
                     FAASLQGPTPLPSFTTVVPNRTPVSGTSSSTQRSSGPVTATSSLYIPAPSRPVTPGGA
                     PEPPTPPSAAAMTSTASIFLSTPLRNSARPEAPGTAAPEPASAREQRISVPAARTGIL
                     QEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAE
                     ACNFMQPLGGRSYKTLSQVSPKTPPPMAPKTPPPMTPKTPPPVAPKPGSRGLPDGLVN
                     GSTSMVGIPELPRLQGRGGELFAKRQSRADRYVVEATPGSSLNPGLRPRSPSPTPSLP
                     PSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPNKAQSQGPRATPKQGIKALDFMRHQ
                     PYQLKTAMFCFDEGPSTPASTSGPPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAA
                     TTLDEPIWRAELASSPVPNPDHLESLRSFAATPTSCGFQVARPRFSATRTGLQAHVWR
                     PGAGHH"
     exon            1..105
                     /gene="Synpo2l"
                     /gene_synonym="RGD1565434"
                     /inference="alignment:Splign:2.1.0"
     exon            106..257
                     /gene="Synpo2l"
                     /gene_synonym="RGD1565434"
                     /inference="alignment:Splign:2.1.0"
     exon            258..772
                     /gene="Synpo2l"
                     /gene_synonym="RGD1565434"
                     /inference="alignment:Splign:2.1.0"
     exon            773..4462
                     /gene="Synpo2l"
                     /gene_synonym="RGD1565434"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgggtgctg aggaggaggt gcaggtcaca ttagcagggg gagcaccctg gggcttccgg
       61 cttcaagggg gggccgaaca gaggaaacct ttacaggtat ctaagatccg aagacgcagc
      121 caggccggca gatcaggact ccgggagagg gaccagctct tatcgatcaa cggggtttct
      181 tgcaccgact tctcccatgc cagtgccatg accctcatcg atgcctcagg gcatcagctt
      241 gtccttactg tgaggagggt agcagaggaa gggtctgtga gatctccgtc tccaggagag
      301 cttcagatgc tgtcaccctt atctccattg agtcctgagc ccccgggtgc tcctgtcacc
      361 caagctcctc agccagggag ccttcgatca ccccctgaca gtgaggctta ctatggagag
      421 acagacagtg atgtggatgg ccctgccaca catgagaagc cacgcagaac ccgccgccga
      481 ggtcctccaa ggccttccct tccaggagct ccacctgatg aggtgtacct gtctgacagc
      541 cccgcagaac cagcgcctgt taaaactggc tctcccagcc agggtgacag ccgtgtaagc
      601 tccccatctt gggaggaagg gtcagccctt cagccaccac cagcagaggc ccttctgtta
      661 ccccatggtc cactccggcc tggtcctcat ctcatcccta tggtgggccc tgtcccccac
      721 ccagtggcag aagatctcac taccacctat acccagaagg ccaagcaagc caaactgcaa
      781 cgcgcggaaa gcctccaaga gaagagtgtg aaggaggcca agaccaaatg ccggaccatt
      841 gcatccctac tgacggcagc ccccaaccct cactccaagg gggtgcttat gtttaagaag
      901 cggcggcaga gagccaagaa gtacacccta gtgagtttcg gggctgcagc tgggacagga
      961 acagaggagg aggaggacgg catcccccca acgagtgagt cggagctgga cgaggaggcc
     1021 ttctcagatg cccgcagcct tactaatcaa tccgactggg acagccctta tctagacatg
     1081 gagctggcta gggctggctc aggcatagca gagagtcaga gctctggact gggaggacag
     1141 ctaagtgagg tctctggccg aggggtacag ctctttgaac agcagcgcca aagggtagcc
     1201 tccagctccc aggagctggc tcaggtgggc ccagcagcca tgcttaatgg gcagagtctg
     1261 cagtccccac ctcgagctca gagtgctccc ccagaggcag cggtgcttcc actcagccct
     1321 ttgtcagccc ctgcagccag ccctagcccc tttcaggatg gtggagcccc cagccctgcg
     1381 ccaagtatct ttaacaggtc agcgagacct tttaccccag gtttaccagg gcaacggtca
     1441 ggcaccacct cagtgatttt ccgacccgta gcccctaaga aggttaatga ggccttgggg
     1501 ggcactagcc ccgccccgtc ccccttcgca gcttctctac aggggcccac ccctctgccc
     1561 agcttcacca ctgtggtgcc caaccgcacg ccggtctctg gaacctccag cagcacccaa
     1621 cgctcctccg gtcctgtgac cgctaccagc tccttgtaca tcccagcccc gagccggccc
     1681 gttacaccag gaggtgcccc agagcctccc actcctccta gcgctgctgc catgacctcc
     1741 actgcttcca tattcttgtc cactcctctg agaaactctg cgcgcccgga ggcacccggc
     1801 acggcggccc ccgagcctgc cagcgctcgg gagcagcgca tctctgtgcc ggctgcccgc
     1861 accggcatcc tgcaggaggc tcggcgccgg ggaacccgca aacagatgtt ccggcctgga
     1921 aaggaagaga cgaagaactc gcccaacccc gagctgctat cgctggtaca gaacctggat
     1981 gaaaaacctc gggcgggcgg tgcggaatct ggtccggagg aggacgcttt aagcctcgga
     2041 gcagaagcct gtaacttcat gcagccacta gggggcagga gttacaagac cctgtctcaa
     2101 gtgtcaccga aaaccccacc tccaatggct cccaaaaccc caccccctat gacgcctaag
     2161 actccacccc ctgtggctcc taaacccggg tctcgagggc tccctgacgg gctagtgaat
     2221 ggatcgacct ctatggttgg gattcctgag ctcccaaggc tgcaggggag gggtggggag
     2281 ctatttgcca aacggcagag ccgtgccgac cggtacgtgg tggaagctac acctggctct
     2341 agccttaatc caggccttcg ccctagaagt ccttctccca caccctcact gcccccatcc
     2401 tggaaatact cacccaacat ccgtgcccca cctcctattg cttacaaccc acttctctca
     2461 ccctttttcc ctcaggctgc ccgaactctc cccaataagg ctcaatccca gggacctcgg
     2521 gcgaccccta agcagggtat caaggccctg gatttcatgc ggcatcagcc ataccaactt
     2581 aaaactgcca tgttttgttt tgacgagggt ccttcaactc ctgcctccac ttcagggcct
     2641 cccaaaactg cccgagtcca ggagatccgc agattttcca ctccggcgcc ccaacccact
     2701 gcagaaccct tggctcccac tgtgcttgcc cccagagcgg ctaccacctt ggacgagccc
     2761 atttggaggg cagagttggc ctcatcccct gtccctaacc cggaccatct agagtctctc
     2821 aggagctttg cggccactcc cacttcctgc ggcttccaag tagccaggcc gcggttctca
     2881 gccaccagaa cagggttgca ggctcatgtc tggagacctg gggcagggca ccactgagca
     2941 gggaataggt cccaggacca agtaatggaa cttagagtcc ccaaagtctc tctcttctgc
     3001 tttgtcctac cggcctcccg tcccccgtcc cccccccctc ccccccgcat ctgagtctga
     3061 ctgcccctag ccagagtgcg ttcccctcag cttcctccct gctggtgctt ttaagcccct
     3121 catctctgct ttggaatctt ctctagatgt ccttgcctgt caggcttctc tacccagaag
     3181 cctcagcaga tttctgcttt tgttttgcat ttgtgtttct ctctgtgggc agcactttag
     3241 tgttaggtaa aaagcacact gtaaagtgac cactgagagc tcaggcaaaa tgctcactcg
     3301 ctctcaggca agcaactaag ggtctgcact gtggcttgat cccctctacc ctccatactc
     3361 ctcactccgc tttccctagg ttagttgcca tacgcctaag ggtgcgtgcg tgcgtgcgtg
     3421 cgtgcgtgtg tgtgtgtgtg tgtgtgtgtg tgtatgtgtg tgtgtgtgtg tgtgtgtatg
     3481 cgcgcgtgct ttcacaaatg tgtgtgatta ggctctgctc tagaaaggca tcaaatacat
     3541 atacatgtgt gcttctcttg aggcaaagga caagacaaga ggagtgtttt cacctactgg
     3601 aagggtcaga tggcttcata aagaatcctg tggggaacaa gagctactgc agaaaagctc
     3661 ctgagagagg agtatctgta gcatggagag agagagagag agagagagag agagagagag
     3721 agagagagag agagagagag agagagagag agagagagag agaggtgcac agcatcttgt
     3781 gaaattaaca agtctgacaa gactgggagg caaggacact tttcatgggt ttgagttata
     3841 caaggtagac ccagaataag actaagaatt ctatttcctt ggattaaagg aagttagcaa
     3901 ccagggccct gtgctgggca catcagaatc cagaaagtaa aaaagaacat ttcttctgaa
     3961 ctgcttaatg agtgtaagat agaaaggatg gtgaatagag ccagagtgga tggggagaac
     4021 gaggcaaaag ccaggaacga ggctggaatg agtgaaagtg aacaaggggg agagtaaagt
     4081 tggccaacat gtgtgagggg gtctgggaac ttctgagctg gggagaacac atttgttaga
     4141 gcaaaggcgt gagcacatgc agtggctgtg ttacctcctg tgaatctgac cttccttcca
     4201 cccttctgga gcttatcccg atgacctggg aaaccaggga gacactgagc ccaaacctct
     4261 tgttgtccca ccctacctgt agaagcccag ctctttgcag cttcaggccc tgtgtctgat
     4321 cccagaagga taaggactat cctcccatga agaccaccat cagttatggt tgttgtttgg
     4381 cctggaaacc aatcttttcc tttgcaatat tgggtgtcac aattctttgg tttgtgcaca
     4441 agaataaacg tatgctcaca ac
//
